-
1
-
-
3943108216
-
Structure and function of TolC: The bacterial exit duct for proteins and drugs
-
Koronakis V, Eswaran J, Hughes C (2004) Structure and function of TolC: The bacterial exit duct for proteins and drugs. Annu Rev Biochem 73:467-489.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 467-489
-
-
Koronakis, V.1
Eswaran, J.2
Hughes, C.3
-
2
-
-
9944247705
-
Three's company: Component structures bring a closer view of tripartite drug efflux pumps
-
Eswaran J, Koronakis E, Higgins MK, Hughes C, Koronakis V (2004) Three's company: Component structures bring a closer view of tripartite drug efflux pumps. Curr Opin Struct Biol 14:741-747.
-
(2004)
Curr Opin Struct Biol
, vol.14
, pp. 741-747
-
-
Eswaran, J.1
Koronakis, E.2
Higgins, M.K.3
Hughes, C.4
Koronakis, V.5
-
3
-
-
0035084352
-
AcrAB and related multidrug efflux pumps of Esche-richia coli
-
Nikaido H, Zgurskaya HI (2001) AcrAB and related multidrug efflux pumps of Esche-richia coli. J Mol Microbiol Biotechnol 3:215-218.
-
(2001)
J Mol Microbiol Biotechnol
, vol.3
, pp. 215-218
-
-
Nikaido, H.1
Zgurskaya, H.I.2
-
4
-
-
0032538793
-
Substrate-induced assembly of a contiguous channel for protein export from Escherichia coli: Reversible bridging of an inner-membrane translocase to an outer membrane exit pore
-
Thanabalu T, Koronakis E, Hughes C, Koronakis V (1998) Substrate-induced assembly of a contiguous channel for protein export from Escherichia coli: Reversible bridging of an inner-membrane translocase to an outer membrane exit pore. EMBO J 17:6487-6496.
-
(1998)
EMBO J
, vol.17
, pp. 6487-6496
-
-
Thanabalu, T.1
Koronakis, E.2
Hughes, C.3
Koronakis, V.4
-
5
-
-
0034791408
-
Multidrug resistance in Gram-negative bacteria
-
Poole K (2001) Multidrug resistance in Gram-negative bacteria. Curr Opin Microbiol 4:500-508.
-
(2001)
Curr Opin Microbiol
, vol.4
, pp. 500-508
-
-
Poole, K.1
-
6
-
-
3542998054
-
AcrA, AcrB, and TolC of Escherichia coli form a stable intermembrane multidrug efflux complex
-
Tikhonova EB, Zgurskaya HI (2004) AcrA, AcrB, and TolC of Escherichia coli form a stable intermembrane multidrug efflux complex. J Biol Chem 279:32116-32124.
-
(2004)
J Biol Chem
, vol.279
, pp. 32116-32124
-
-
Tikhonova, E.B.1
Zgurskaya, H.I.2
-
7
-
-
64649087897
-
Structural and functional diversity of bacterial membrane fusion proteins
-
10.1061/j.bbapap.2008.010
-
Zgurskaya HI, Yamada Y, Tikhonova EB, Ge Q, Krishnamoorthy G (2009) Structural and functional diversity of bacterial membrane fusion proteins. Biochim Biophys Acta, 10.1061/j.bbapap.2008.010.
-
(2009)
Biochim Biophys Acta
-
-
Zgurskaya, H.I.1
Yamada, Y.2
Tikhonova, E.B.3
Ge, Q.4
Krishnamoorthy, G.5
-
8
-
-
0034702177
-
Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
-
Koronakis V, Sharff A, Koronakis E, Luisi B, Hughes C (2000) Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export. Nature 405:914-919.
-
(2000)
Nature
, vol.405
, pp. 914-919
-
-
Koronakis, V.1
Sharff, A.2
Koronakis, E.3
Luisi, B.4
Hughes, C.5
-
9
-
-
0037057652
-
Crystal structure of bacterial multidrug efflux transporter AcrB
-
Murakami S, Nakashima R, Yamashita E, Yamaguchi A (2002) Crystal structure of bacterial multidrug efflux transporter AcrB. Nature 419:587-593.
-
(2002)
Nature
, vol.419
, pp. 587-593
-
-
Murakami, S.1
Nakashima, R.2
Yamashita, E.3
Yamaguchi, A.4
-
10
-
-
0038670226
-
Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump
-
Yu EW, McDermott G, Zgurskaya HI, Nikaido H, Koshland DE (2003) Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science 300:976-980.
-
(2003)
Science
, vol.300
, pp. 976-980
-
-
Yu, E.W.1
McDermott, G.2
Zgurskaya, H.I.3
Nikaido, H.4
Koshland, D.E.5
-
11
-
-
0037143615
-
Transition to the open state of the TolC periplasmic tunnel entrance
-
Andersen C, et al. (2002) Transition to the open state of the TolC periplasmic tunnel entrance. Proc Natl Acad Sci USA 99:11103-11108.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11103-11108
-
-
Andersen, C.1
-
12
-
-
0037459244
-
Locking TolC entrance helices to prevent protein translocation by the bacterial type I export apparatus
-
Eswaran J, Hughes C, Koronakis V (2003) Locking TolC entrance helices to prevent protein translocation by the bacterial type I export apparatus. J Mol Biol 327:309-315.
-
(2003)
J Mol Biol
, vol.327
, pp. 309-315
-
-
Eswaran, J.1
Hughes, C.2
Koronakis, V.3
-
13
-
-
41549158741
-
Assembly and channel opening in a bacterial drug efflux machine
-
Bavro VN, et al. (2008) Assembly and channel opening in a bacterial drug efflux machine. Mol Cell 30:114-121.
-
(2008)
Mol Cell
, vol.30
, pp. 114-121
-
-
Bavro, V.N.1
-
14
-
-
33748670458
-
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
-
Murakami S, Nakashima R, Yamashita E, Matsumoto T, Yamaguchi A (2006) Crystal structures of a multidrug transporter reveal a functionally rotating mechanism. Nature 443:173-179.
-
(2006)
Nature
, vol.443
, pp. 173-179
-
-
Murakami, S.1
Nakashima, R.2
Yamashita, E.3
Matsumoto, T.4
Yamaguchi, A.5
-
15
-
-
33748310520
-
Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism
-
Seeger MA, et al. (2006) Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism. Science 313:1295-1298.
-
(2006)
Science
, vol.313
, pp. 1295-1298
-
-
Seeger, M.A.1
-
16
-
-
49549088341
-
Multidrug efflux transporter, AcrB: The pumping mechanism
-
Murakami S (2008) Multidrug efflux transporter, AcrB: The pumping mechanism. Curr Opin Struct Biol 18:459-465.
-
(2008)
Curr Opin Struct Biol
, vol.18
, pp. 459-465
-
-
Murakami, S.1
-
17
-
-
3242890387
-
Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system
-
Touzé T, et al. (2004) Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system. Mol Microbiol 53:697-706.
-
(2004)
Mol Microbiol
, vol.53
, pp. 697-706
-
-
Touzé, T.1
-
18
-
-
23944509010
-
Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking
-
Tamura N, Murakami S, Oyama Y, Ishiguro M, Yamaguchi A (2005) Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking. Biochemistry 44:11115-11121.
-
(2005)
Biochemistry
, vol.44
, pp. 11115-11121
-
-
Tamura, N.1
Murakami, S.2
Oyama, Y.3
Ishiguro, M.4
Yamaguchi, A.5
-
19
-
-
3042838743
-
Structure of the periplasmic component of a bacterial drug efflux pump
-
Higgins MK, Bokma E, Koronakis E, Hughes C, Koronakis V (2004) Structure of the periplasmic component of a bacterial drug efflux pump. Proc Natl Acad Sci USA 101:9994-9999.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9994-9999
-
-
Higgins, M.K.1
Bokma, E.2
Koronakis, E.3
Hughes, C.4
Koronakis, V.5
-
20
-
-
2942731519
-
Crystal structure of the membrane fusion protein MexA of the multidrug transporter in Pseudomonas aeruginosa
-
Akama H, et al. (2004) Crystal structure of the membrane fusion protein MexA of the multidrug transporter in Pseudomonas aeruginosa. J Biol Chem 279:25939-25942.
-
(2004)
J Biol Chem
, vol.279
, pp. 25939-25942
-
-
Akama, H.1
-
21
-
-
0033515434
-
Alignment and structure prediction of divergent protein families: Periplasmic and outer membrane proteins of bacterial efflux pumps
-
Johnson JM, Church GM (1999) Alignment and structure prediction of divergent protein families: Periplasmic and outer membrane proteins of bacterial efflux pumps. J Mol Biol 287:695-715.
-
(1999)
J Mol Biol
, vol.287
, pp. 695-715
-
-
Johnson, J.M.1
Church, G.M.2
-
23
-
-
34248359106
-
A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps
-
Lobedanz S, et al. (2007) A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps. Proc Natl Acad Sci USA 104:4612-4617.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 4612-4617
-
-
Lobedanz, S.1
-
24
-
-
0346749468
-
pH-induced conformational changes of AcrA the membrane fusion protein of Escherichia coli multidrug efflux system
-
Ip H, Stratton K, Zgurskaya H, Liu J (2003) pH-induced conformational changes of AcrA the membrane fusion protein of Escherichia coli multidrug efflux system. J Biol Chem 278:50474-50482.
-
(2003)
J Biol Chem
, vol.278
, pp. 50474-50482
-
-
Ip, H.1
Stratton, K.2
Zgurskaya, H.3
Liu, J.4
-
25
-
-
0034681390
-
Function of the membrane fusion protein MexA of the MexAB-OprM efflux pump in Pseudomonas aeruginosa without an anchoring membrane
-
Yoneyama H, Maseda H, Kamiguchi H, Nakae T (2000) Function of the membrane fusion protein MexA of the MexAB-OprM efflux pump in Pseudomonas aeruginosa without an anchoring membrane. J Biol Chem 275:4628-4634.
-
(2000)
J Biol Chem
, vol.275
, pp. 4628-4634
-
-
Yoneyama, H.1
Maseda, H.2
Kamiguchi, H.3
Nakae, T.4
-
26
-
-
0042838181
-
Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pump
-
Elkins CA, Nikaido H (2003) Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pump. J Bacteriol 185:5349-5356.
-
(2003)
J Bacteriol
, vol.185
, pp. 5349-5356
-
-
Elkins, C.A.1
Nikaido, H.2
-
27
-
-
0036889445
-
Chimeric analysis of the multicomponent multidrug efflux transporters from Gram-negative bacteria
-
Tikhonova EB, Wang Q, Zgurskaya HI (2002) Chimeric analysis of the multicomponent multidrug efflux transporters from Gram-negative bacteria. J Bacteriol 184:6499-6507.
-
(2002)
J Bacteriol
, vol.184
, pp. 6499-6507
-
-
Tikhonova, E.B.1
Wang, Q.2
Zgurskaya, H.I.3
-
28
-
-
38749137423
-
Fitting periplasmic membrane fusion proteins to inner membrane transporters: Mutations that enable Escherichia coli AcrA to function with Pseudomonas aeruginosa MexB
-
Krishnamoorthy G, Tikhonova EB, Zgurskaya HI (2008) Fitting periplasmic membrane fusion proteins to inner membrane transporters: mutations that enable Escherichia coli AcrA to function with Pseudomonas aeruginosa MexB. J Bacteriol 190:691-698.
-
(2008)
J Bacteriol
, vol.190
, pp. 691-698
-
-
Krishnamoorthy, G.1
Tikhonova, E.B.2
Zgurskaya, H.I.3
-
29
-
-
0034193510
-
Protein docking using spherical polar Fourier correlations
-
Ritchie DW, Kemp GJ (2000) Protein docking using spherical polar Fourier correlations. Proteins 39:178-194.
-
(2000)
Proteins
, vol.39
, pp. 178-194
-
-
Ritchie, D.W.1
Kemp, G.J.2
-
30
-
-
9644281653
-
A model of a transmembrane drug-efflux pump from Gram-negative bacteria
-
Fernandez-Recio J, et al. (2004) A model of a transmembrane drug-efflux pump from Gram-negative bacteria. FEBS Lett 578:5-9.
-
(2004)
FEBS Lett
, vol.578
, pp. 5-9
-
-
Fernandez-Recio, J.1
-
31
-
-
33745686037
-
Flexibility in a drug transport accessory protein: Molecular dynamics simulations of MexA
-
Vaccaro L, Koronakis V, Sansom MS (2006) Flexibility in a drug transport accessory protein: Molecular dynamics simulations of MexA. Biophys J 91:558-564.
-
(2006)
Biophys J
, vol.91
, pp. 558-564
-
-
Vaccaro, L.1
Koronakis, V.2
Sansom, M.S.3
-
32
-
-
33846363597
-
Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors
-
Sennhauser G, Amstutz P, Briand C, Storchenegger O, Grü tter MGG (2006) Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors. PLoS Biol 5:e7.
-
(2006)
PLoS Biol
, vol.5
-
-
Sennhauser, G.1
Amstutz, P.2
Briand, C.3
Storchenegger, O.4
Grü tter, M.G.G.5
-
33
-
-
57349135305
-
Site-directed mutagenesis reveals putative substrate binding residues in the Escherichia coli RND efflux pump AcrB
-
Bohnert JA, et al. (2008) Site-directed mutagenesis reveals putative substrate binding residues in the Escherichia coli RND efflux pump AcrB. J Bacteriol 190:8225-8229.
-
(2008)
J Bacteriol
, vol.190
, pp. 8225-8229
-
-
Bohnert, J.A.1
-
34
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
Emsley P, Cowtan K (2004) Coot: Model-building tools for molecular graphics. Acta Crystallogr D 60:2126-2132.
-
(2004)
Acta Crystallogr D
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
35
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography
-
4
-
CCP4 (1994) The CCP4 suite: Programs for protein crystallography. Acta Crystallogr D 50:760-763.
-
(1994)
Acta Crystallogr D
, vol.50
, pp. 760-763
-
-
CCP1
-
36
-
-
3543012707
-
Crystallography, NMR system: A new software suite for macromolecular structure determination
-
Brü nger AT, et al. (1998) Crystallography, NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D 54:905-921.
-
(1998)
Acta Crystallogr D
, vol.54
, pp. 905-921
-
-
Brü nger, A.T.1
-
37
-
-
14244272868
-
PHENIX: Building new software for automated crystallographic structure determination
-
Adams PD, et al. (2002) PHENIX: Building new software for automated crystallographic structure determination. Acta Crystallogr D 58:1948-1954.
-
(2002)
Acta Crystallogr D
, vol.58
, pp. 1948-1954
-
-
Adams, P.D.1
-
39
-
-
0017807890
-
Construction and characterization of amplifiable multi-copy DNA cloning vehicles derived from the P15A cryptic miniplasmid
-
Chang AC, Cohen SN (1978) Construction and characterization of amplifiable multi-copy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J Bacteriol 134:1141-1156.
-
(1978)
J Bacteriol
, vol.134
, pp. 1141-1156
-
-
Chang, A.C.1
Cohen, S.N.2
-
40
-
-
1942470540
-
Mapping the topology and determination of a low-resolution 3-dimensional structure of the calmodulin-melittin complex by chemical cross-linking
-
Schulz DM, Ihling C, Clore GM, Sinz A (2004) Mapping the topology and determination of a low-resolution 3-dimensional structure of the calmodulin-melittin complex by chemical cross-linking. Biochemistry 43:4703-4715.
-
(2004)
Biochemistry
, vol.43
, pp. 4703-4715
-
-
Schulz, D.M.1
Ihling, C.2
Clore, G.M.3
Sinz, A.4
|