Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 24, 2010, Pages 11038-11043

  De Angelis, Fabien ^a   Lee, John K ^b   O'Connell III, Joseph D ^b   Miercke, Larry J W ^b   Verschueren, Koen H ^c   Srinivasan, Vasundara ^c   Bauvois, Cédric ^d   Govaerts, Cédric ^a   Robbins, Rebecca A ^b   Ruysschaert, Jean Marie ^a   Stroud, Robert M ^b   Vandenbussche, Guy ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d Institut de Recherches Microbiologiques J M Wiame   (Belgium)

Author keywords

Cupriavidus metallidurans CH34; Heavy metal resistance; Periplasmic adaptor protein; Resistance nodulation cell division

Indexed keywords

ANTIPORTER; HEAVY METAL; MEMBRANE FUSION PROTEIN; MEMBRANE PROTEIN; METAL ION; RND PROTEIN; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; BACTERIAL MEMBRANE; CELL DIVISION; CHROMATOGRAPHY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CUPRIAVIDUS; CUPRIAVIDUS METALLIDURANS; ENZYME SUBSTRATE; MEMBRANE FUSION; MEMBRANE RESISTANCE; METAL BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TRANSPORT; SPECTROSCOPY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BINDING SITES; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; CRYSTALLOGRAPHY, X-RAY; CUPRIAVIDUS; DRUG RESISTANCE, BACTERIAL; MEMBRANE FUSION PROTEINS; METALS, HEAVY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PHYLOGENY; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; ZINC;

CUPRIAVIDUS METALLIDURANS; NEGIBACTERIA;

EID: 77954656149     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1003908107     Document Type: Article

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