Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug efflux protein TolC

Journal of Molecular Biology

Volumn 342, Issue 3, 2004, Pages 697-702

  Higgins, Matthew K ^a   Eswaran, Jeyanthy ^a   Edwards, Patricia ^b   Schertler, Gebhard F X ^b   Hughes, Colin ^a   Koronakis, Vassilis ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

antibacterial drugs; ligand binding; multidrug resistance; TolC entrance

Indexed keywords

ALANINE; ASPARTIC ACID; COBALT DERIVATIVE; LIGAND; MULTIDRUG RESISTANCE PROTEIN; TOLC PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CALORIMETRY; CIRCLING BEHAVIOR; COMPARATIVE STUDY; CONDUCTANCE; CRYSTAL STRUCTURE; CYTOPLASM; DENSITY; ELECTRON; ESCHERICHIA COLI; HYDROGEN BOND; INTRACELLULAR TRANSPORT; ISOTHERM; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; PROTEIN TRANSPORT;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 4444252811     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.07.088     Document Type: Article

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