Polycyclic aromatic hydrocarbons: From metabolism to lung cancer

Toxicological Sciences

Volumn 145, Issue 1, 2015, Pages 5-15

  Moorthy, Bhagavatula ^a   Chu, Chun ^a   Carlin, Danielle J ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Ah receptor; Carcinogenesis; Genetic susceptibility; Lung cancer; Metabolism; Mixtures; PAH; Polycyclic aromatic hydrocarbons

Indexed keywords

ALDO KETO REDUCTASE; AROMATIC HYDROCARBON RECEPTOR; CARCINOGEN; CATION; CHARCOAL; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; DIOL EPOXIDE; DNA; EPOXIDE; EPOXIDE HYDROLASE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; OXIDOREDUCTASE; PEROXIDASE; POLYCYCLIC AROMATIC HYDROCARBON; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; XENOBIOTIC AGENT;

CANCER MORTALITY; CARCINOGENESIS; DETOXIFICATION; DIET; DNA ADDUCT; ETHNICITY; GENE; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; HUMAN; LUNG CANCER; LUNG CARCINOGENESIS; METABOLIC ACTIVATION; METABOLISM; METABOLITE; MUTATION; REVIEW; TUMOR SUPPRESSOR GENE; UNITED STATES; CHEMICALLY INDUCED; LUNG TUMOR;

ACTIVATION, METABOLIC; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; LUNG NEOPLASMS; POLYCYCLIC AROMATIC HYDROCARBONS;

EID: 84929666826     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv040     Document Type: Review

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