-
1
-
-
79960929526
-
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese
-
Hu, Z. et al. A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat. Genet. 43, 792-796 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 792-796
-
-
Hu, Z.1
-
2
-
-
56749182096
-
Lung cancer susceptibility locus at 5P15.33
-
McKay, J.D. et al. Lung cancer susceptibility locus at 5p15.33. Nat. Genet. 40, 1404-1406 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 1404-1406
-
-
McKay, J.D.1
-
3
-
-
56749163357
-
Common 5P15.33 and 6P21.33 variants influence lung cancer risk
-
Wang, Y. et al. Common 5p15.33 and 6p21.33 variants influence lung cancer risk. Nat. Genet. 40, 1407-1409 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 1407-1409
-
-
Wang, Y.1
-
4
-
-
41649103682
-
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
-
Hung, R.J. et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452, 633-637 (2008).
-
(2008)
Nature
, vol.452
, pp. 633-637
-
-
Hung, R.J.1
-
5
-
-
77957588624
-
Variation in tp63 is associated with lung adenocarcinoma susceptibility in japanese and korean populations
-
Miki, D. et al. Variation in tp63 is associated with lung adenocarcinoma susceptibility in japanese and korean populations. Nat. Genet. 42, 893-896 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 893-896
-
-
Miki, D.1
-
6
-
-
42649091460
-
Genome-wide association scan of tag snps identifies a susceptibility locus for lung cancer at 15q25.1
-
Amos, C.I. et al. Genome-wide association scan of tag snps identifies a susceptibility locus for lung cancer at 15q25.1. Nat. Genet. 40, 616-622 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 616-622
-
-
Amos, C.I.1
-
7
-
-
77950341944
-
Genetic variants and risk of lung cancer in never smokers: A genome-wide association study
-
Li, Y. et al. Genetic variants and risk of lung cancer in never smokers: a genome-wide association study. Lancet Oncol. 11, 321-330 (2010).
-
(2010)
Lancet Oncol
, vol.11
, pp. 321-330
-
-
Li, Y.1
-
8
-
-
84859497097
-
The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in korean populations
-
Ahn, M.J. et al. The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations. Hum. Genet. 131, 365-372 (2012).
-
(2012)
Hum. Genet.
, vol.131
, pp. 365-372
-
-
Ahn, M.J.1
-
9
-
-
78649456727
-
A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population
-
Yoon, K.A. et al. A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population. Hum. Mol. Genet. 19, 4948-4954 (2010).
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4948-4954
-
-
Yoon, K.A.1
-
10
-
-
41649103052
-
A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
-
Thorgeirsson, T.E. et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452, 638-642 (2008).
-
(2008)
Nature
, vol.452
, pp. 638-642
-
-
Thorgeirsson, T.E.1
-
11
-
-
77956637896
-
Genetics and beyond - The transcriptome of human monocytes and disease susceptibility
-
Zeller, T. et al. Genetics and beyond-the transcriptome of human monocytes and disease susceptibility. PLoS ONE 5, e10693 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Zeller, T.1
-
12
-
-
34547742562
-
C-myb regulates lineage choice in developing thymocytes via its target gene gata3
-
Maurice, D., Hooper, J., Lang, G. & Weston, K. c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3. EMBO J. 26, 3629-3640 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 3629-3640
-
-
Maurice, D.1
Hooper, J.2
Lang, G.3
Weston, K.4
-
13
-
-
78649471895
-
A genome-wide association study of hodgkin's lymphoma identifies new susceptibility loci at 2P16.1 (REL), 8Q24.21 and 10p14 (GATA3)
-
Enciso-Mora, V. et al. A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3). Nat. Genet. 42, 1126-1130 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 1126-1130
-
-
Enciso-Mora, V.1
-
14
-
-
79953329774
-
The notch ligand jagged2 promotes lung adenocarcinoma metastasis through a mir-200-dependent pathway in mice
-
Yang, Y. et al. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J. Clin. Invest. 121, 1373-1385 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1373-1385
-
-
Yang, Y.1
-
16
-
-
83255186736
-
Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14
-
Asselin-Labat, M.L. et al. Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14. Mol. Cell. Biol. 31, 4609-4622 (2011).
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 4609-4622
-
-
Asselin-Labat, M.L.1
-
17
-
-
0023062990
-
Protein serine/threonine kinases
-
Edelman, A.M., Blumenthal, D.K. & Krebs, E.G. Protein serine/threonine kinases. Annu. Rev. Biochem. 56, 567-613 (1987).
-
(1987)
Annu. Rev. Biochem.
, vol.56
, pp. 567-613
-
-
Edelman, A.M.1
Blumenthal, D.K.2
Krebs, E.G.3
-
18
-
-
78249287240
-
B55β-associated pp2a complex controls pdk1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer
-
Tan, J. et al. B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer. Cancer Cell 18, 459-471 (2010).
-
(2010)
Cancer Cell
, vol.18
, pp. 459-471
-
-
Tan, J.1
-
19
-
-
78049446499
-
A set of genes associated with the interferon-γ response of lung cancer patients undergoing α-galactosylceramide-pulsed dendritic cell therapy
-
Okita, K. et al. A set of genes associated with the interferon-γ response of lung cancer patients undergoing α-galactosylceramide-pulsed dendritic cell therapy. Cancer Sci. 101, 2333-2340 (2010).
-
(2010)
Cancer Sci
, vol.101
, pp. 2333-2340
-
-
Okita, K.1
-
20
-
-
77957551804
-
The 5P15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in asia
-
Hsiung, C.A. et al. The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet. 6, e1001051 (2010).
-
(2010)
PLoS Genet
, vol.6
-
-
Hsiung, C.A.1
-
21
-
-
0028047731
-
Antiproliferative effects of 1,25-dihydroxyvitamin D3 on primary cultures of human prostatic cells
-
Peehl, D.M. et al. Antiproliferative effects of 1,25-dihydroxyvitamin D3 on primary cultures of human prostatic cells. Cancer Res. 54, 805-810 (1994).
-
(1994)
Cancer Res
, vol.54
, pp. 805-810
-
-
Peehl, D.M.1
-
22
-
-
34547631980
-
Clinical validity of the lung cancer biomarkers identified by bioinformatics analysis of public expression data
-
Kim, B. et al. Clinical validity of the lung cancer biomarkers identified by bioinformatics analysis of public expression data. Cancer Res. 67, 7431-7438 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 7431-7438
-
-
Kim, B.1
-
23
-
-
28844507235
-
Expression of VDR and CYP24A1 mRNA in human tumors
-
Anderson, M.G., Nakane, M., Ruan, X., Kroeger, P.E. & Wu-Wong, J.R. Expression of VDR and CYP24A1 mRNA in human tumors. Cancer Chemother. Pharmacol. 57, 234-240 (2006).
-
(2006)
Cancer Chemother. Pharmacol.
, vol.57
, pp. 234-240
-
-
Anderson, M.G.1
Nakane, M.2
Ruan, X.3
Kroeger, P.E.4
Wu-Wong, J.R.5
-
24
-
-
79951837361
-
Cyp24a1 is an independent prognostic marker of survival in patients with lung adenocarcinoma
-
Chen, G. et al. CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma. Clin. Cancer Res. 17, 817-826 (2011).
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 817-826
-
-
Chen, G.1
-
25
-
-
65549157442
-
The aryl hydrocarbon receptor activator benzoapyrene enhances vitamin D3 catabolism in macrophages
-
Matsunawa, M. et al. The aryl hydrocarbon receptor activator benzoapyrene enhances vitamin D3 catabolism in macrophages. Toxicol. Sci. 109, 50-58 (2009).
-
(2009)
Toxicol. Sci.
, vol.109
, pp. 50-58
-
-
Matsunawa, M.1
-
26
-
-
0027474413
-
Local expression of antiinflammatory cytokines in cancer
-
Yamamura, M., Modlin, R.L., Ohmen, J.D. & Moy, R.L. Local expression of antiinflammatory cytokines in cancer. J. Clin. Invest. 91, 1005-1010 (1993).
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 1005-1010
-
-
Yamamura, M.1
Modlin, R.L.2
Ohmen, J.D.3
Moy, R.L.4
-
27
-
-
0029124129
-
Human non-small cell lung cancer cells express a type 2 cytokine pattern
-
Huang, M. et al. Human non-small cell lung cancer cells express a type 2 cytokine pattern. Cancer Res. 55, 3847-3853 (1995).
-
(1995)
Cancer Res
, vol.55
, pp. 3847-3853
-
-
Huang, M.1
-
28
-
-
77954045735
-
Plasmacytoid dendritic cells prevent cigarette smoke and Chlamydophila pneumoniae-induced Th2 inflammatory responses
-
Sorrentino, R. et al. Plasmacytoid dendritic cells prevent cigarette smoke and Chlamydophila pneumoniae-induced Th2 inflammatory responses. Am. J. Respir. Cell Mol. Biol. 43, 422-431 (2010).
-
(2010)
Am. J. Respir. Cell Mol. Biol.
, vol.43
, pp. 422-431
-
-
Sorrentino, R.1
-
29
-
-
23444459236
-
Cigarette smoke extract suppresses human dendritic cell function leading to preferential induction of th-2 priming
-
Vassallo, R., Tamada, K., Lau, J.S., Kroening, P.R. & Chen, L. Cigarette smoke extract suppresses human dendritic cell function leading to preferential induction of Th-2 priming. J. Immunol. 175, 2684-2691 (2005).
-
(2005)
J. Immunol.
, vol.175
, pp. 2684-2691
-
-
Vassallo, R.1
Tamada, K.2
Lau, J.S.3
Kroening, P.R.4
Chen, L.5
-
30
-
-
33747619857
-
P53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase
-
Teodoro, J.G., Parker, A.E., Zhu, X. & Green, M.R. p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase. Science 313, 968-971 (2006).
-
(2006)
Science
, vol.313
, pp. 968-971
-
-
Teodoro, J.G.1
Parker, A.E.2
Zhu, X.3
Green, M.R.4
-
31
-
-
79957884873
-
A dual role for the immune response in a mouse model of inflammation-associated lung cancer
-
Dougan, M. et al. A dual role for the immune response in a mouse model of inflammation-associated lung cancer. J. Clin. Invest. 121, 2436-2446 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2436-2446
-
-
Dougan, M.1
-
32
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt, M.F. et al. A large-scale, consortium-based genomewide association study of asthma. N. Engl. J. Med. 363, 1211-1221 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1211-1221
-
-
Moffatt, M.F.1
-
33
-
-
71849088563
-
Mouse octn2 is directly regulated by peroxisome proliferator-activated receptor α (PPARα) via a PPRE located in the first intron
-
Wen, G., Ringseis, R. & Eder, K. Mouse OCTN2 is directly regulated by peroxisome proliferator-activated receptor α (PPARα) via a PPRE located in the first intron. Biochem. Pharmacol. 79, 768-776 (2010).
-
(2010)
Biochem. Pharmacol.
, vol.79
, pp. 768-776
-
-
Wen, G.1
Ringseis, R.2
Eder, K.3
-
34
-
-
78649740044
-
Roles of peroxisome proliferator-activated receptor-α and-γ in the development of non-small cell lung cancer
-
Li, M.Y. et al. Roles of peroxisome proliferator-activated receptor-α and-γ in the development of non-small cell lung cancer. Am. J. Respir. Cell Mol. Biol. 43, 674-683 (2010).
-
(2010)
Am. J. Respir. Cell Mol. Biol.
, vol.43
, pp. 674-683
-
-
Li, M.Y.1
-
35
-
-
83755196447
-
Acsl6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure
-
Chen, J. et al. ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure. PLoS ONE 6, e28790 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Chen, J.1
-
36
-
-
33646419301
-
The shrew1 gene, frequently deleted in oligodendrogliomas, functions to inhibit cell adhesion and migration
-
McDonald, J.M. et al. The SHREW1 gene, frequently deleted in oligodendrogliomas, functions to inhibit cell adhesion and migration. Cancer Biol. Ther. 5, 300-304 (2006).
-
(2006)
Cancer Biol. Ther.
, vol.5
, pp. 300-304
-
-
McDonald, J.M.1
-
37
-
-
79958182034
-
Nphp4, a cilia-associated protein, negatively regulates the hippo pathway
-
Habbig, S. et al. NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway. J. Cell Biol. 193, 633-642 (2011).
-
(2011)
J. Cell Biol.
, vol.193
, pp. 633-642
-
-
Habbig, S.1
-
38
-
-
34548805282
-
A genome-wide association study of global gene expression
-
Dixon, A.L. et al. A genome-wide association study of global gene expression. Nat. Genet. 39, 1202-1207 (2007).
-
(2007)
Nat. Genet.
, vol.39
, pp. 1202-1207
-
-
Dixon, A.L.1
-
39
-
-
34548738566
-
Population genomics of human gene expression
-
Stranger, B.E. et al. Population genomics of human gene expression. Nat. Genet. 39, 1217-1224 (2007).
-
(2007)
Nat. Genet.
, vol.39
, pp. 1217-1224
-
-
Stranger, B.E.1
-
40
-
-
55449112450
-
High-resolution mapping of expression-qtls yields insight into human gene regulation
-
Veyrieras, J.B. et al. High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 4, e1000214 (2008).
-
(2008)
PLoS Genet
, vol.4
-
-
Veyrieras, J.B.1
-
41
-
-
77950460661
-
Understanding mechanisms underlying human gene expression variation with RNA sequencing
-
Pickrell, J.K. et al. Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature 464, 768-772 (2010).
-
(2010)
Nature
, vol.464
, pp. 768-772
-
-
Pickrell, J.K.1
-
42
-
-
77950458649
-
Transcriptome genetics using second generation sequencing in a Caucasian population
-
Montgomery, S.B. et al. Transcriptome genetics using second generation sequencing in a Caucasian population. Nature 464, 773-777 (2010).
-
(2010)
Nature
, vol.464
, pp. 773-777
-
-
Montgomery, S.B.1
-
43
-
-
69949176863
-
Common regulatory variation impacts gene expression in a cell type-dependent manner
-
Dimas, A.S. et al. Common regulatory variation impacts gene expression in a cell type-dependent manner. Science 325, 1246-1250 (2009).
-
(2009)
Science
, vol.325
, pp. 1246-1250
-
-
Dimas, A.S.1
-
44
-
-
45149108420
-
Mapping the genetic architecture of gene expression in human liver
-
Schadt, E.E. et al. Mapping the genetic architecture of gene expression in human liver. PLoS Biol. 6, e107 (2008).
-
(2008)
PLoS Biol
, vol.6
-
-
Schadt, E.E.1
-
45
-
-
36549053104
-
A survey of genetic human cortical gene expression
-
Myers, A.J. et al. A survey of genetic human cortical gene expression. Nat. Genet. 39, 1494-1499 (2007).
-
(2007)
Nat. Genet.
, vol.39
, pp. 1494-1499
-
-
Myers, A.J.1
|