Persistent induction of cytochrome P4501A1 in human hepatoma cells by 3-methylcholanthrene: Evidence for sustained transcriptional activation of the CYP1A1 promoter

Journal of Pharmacology and Experimental Therapeutics

Volumn 333, Issue 1, 2010, Pages 99-109

  Fazili, Inayat S ^a   Jiang, Weiwu ^a   Wang, Lihua ^a   Felix, Edward A ^b   Khatlani, Tanvir ^a   Coumoul, Xavier ^c   Barouki, Robert ^c   Moorthy, Bhagavatula ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLCHOLANTHRENE; APOPROTEIN; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; ETHOXYRESORUFIN DEETHYLASE; MESSENGER RNA;

ARTICLE; CARCINOGENESIS; CELL STRAIN HEPG2; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENETIC TRANSFECTION; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIQUID CHROMATOGRAPHY; METABOLITE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TANDEM MASS SPECTROMETRY; TRANSCRIPTION INITIATION;

CARCINOGENS; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; HUMANS; METHYLCHOLANTHRENE; PROMOTER REGIONS, GENETIC; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; TRANSCRIPTIONAL ACTIVATION;

EID: 77949672491     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.162222     Document Type: Article

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