-
2
-
-
70349895519
-
Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital: implications for antibiotic stewardship
-
Roberts, R. R.; Hota, B.; Ahmad, I.; Scott, R. D., 2nd; Foster, S. D.; Abbasi, F.; Schabowski, S.; Kampe, L. M.; Ciavarella, G. G.; Supino, M.; Naples, J.; Cordell, R.; Levy, S. B.; Weinstein, R. A. Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital: implications for antibiotic stewardship Clin. Infect. Dis. 2009, 49, 1175-1184
-
(2009)
Clin. Infect. Dis.
, vol.49
, pp. 1175-1184
-
-
Roberts, R.R.1
Hota, B.2
Ahmad, I.3
Scott, R.D.4
Foster, S.D.5
Abbasi, F.6
Schabowski, S.7
Kampe, L.M.8
Ciavarella, G.G.9
Supino, M.10
Naples, J.11
Cordell, R.12
Levy, S.B.13
Weinstein, R.A.14
-
6
-
-
33845700514
-
Riboswitches as antibacterial drug targets
-
Blount, K. F.; Breaker, R. R. Riboswitches as antibacterial drug targets Nat. Biotechnol. 2006, 24, 1558-1564
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1558-1564
-
-
Blount, K.F.1
Breaker, R.R.2
-
7
-
-
80053041142
-
Riboswitches: discovery of drugs that target bacterial gene-regulatory RNAs
-
Deigan, K. E.; Ferre-D'Amare, A. R. Riboswitches: discovery of drugs that target bacterial gene-regulatory RNAs Acc. Chem. Res. 2011, 44, 1329-1338
-
(2011)
Acc. Chem. Res.
, vol.44
, pp. 1329-1338
-
-
Deigan, K.E.1
Ferre-D'Amare, A.R.2
-
8
-
-
84871549196
-
Riboswitch-based antibacterial drug discovery using high-throughput screening methods
-
Penchovsky, R.; Stoilova, C. C. Riboswitch-based antibacterial drug discovery using high-throughput screening methods Expert Opin. Drug Discovery 2013, 8, 65-82
-
(2013)
Expert Opin. Drug Discovery
, vol.8
, pp. 65-82
-
-
Penchovsky, R.1
Stoilova, C.C.2
-
9
-
-
80052973462
-
Prospects for riboswitch discovery and analysis
-
Breaker, R. R. Prospects for riboswitch discovery and analysis Mol. Cell 2011, 43, 867-879
-
(2011)
Mol. Cell
, vol.43
, pp. 867-879
-
-
Breaker, R.R.1
-
10
-
-
84870954236
-
Dual-acting riboswitch control of translation initiation and mRNA decay
-
Caron, M. P.; Bastet, L.; Lussier, A.; Simoneau-Roy, M.; Masse, E.; Lafontaine, D. A. Dual-acting riboswitch control of translation initiation and mRNA decay Proc. Natl. Acad. Sci. U.S.A. 2012, 109, E3444-E3453
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. E3444-E3453
-
-
Caron, M.P.1
Bastet, L.2
Lussier, A.3
Simoneau-Roy, M.4
Masse, E.5
Lafontaine, D.A.6
-
11
-
-
84859475820
-
Riboswitch control of Rho-dependent transcription termination
-
Hollands, K.; Proshkin, S.; Sklyarova, S.; Epshtein, V.; Mironov, A.; Nudler, E.; Groisman, E. A. Riboswitch control of Rho-dependent transcription termination Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 5376-5381
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 5376-5381
-
-
Hollands, K.1
Proshkin, S.2
Sklyarova, S.3
Epshtein, V.4
Mironov, A.5
Nudler, E.6
Groisman, E.A.7
-
12
-
-
70350771280
-
A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes
-
Loh, E.; Dussurget, O.; Gripenland, J.; Vaitkevicius, K.; Tiensuu, T.; Mandin, P.; Repoila, F.; Buchrieser, C.; Cossart, P.; Johansson, J. A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes Cell 2009, 139, 770-779
-
(2009)
Cell
, vol.139
, pp. 770-779
-
-
Loh, E.1
Dussurget, O.2
Gripenland, J.3
Vaitkevicius, K.4
Tiensuu, T.5
Mandin, P.6
Repoila, F.7
Buchrieser, C.8
Cossart, P.9
Johansson, J.10
-
13
-
-
0037206833
-
Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression
-
Winkler, W.; Nahvi, A.; Breaker, R. R. Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression Nature 2002, 419, 952-956
-
(2002)
Nature
, vol.419
, pp. 952-956
-
-
Winkler, W.1
Nahvi, A.2
Breaker, R.R.3
-
14
-
-
0031735563
-
The S box regulon: a new global transcription termination control system for methionine and cysteine biosynthesis genes in Gram-positive bacteria
-
Grundy, F. J.; Henkin, T. M. The S box regulon: a new global transcription termination control system for methionine and cysteine biosynthesis genes in Gram-positive bacteria Mol. Microbiol. 1998, 30, 737-749
-
(1998)
Mol. Microbiol.
, vol.30
, pp. 737-749
-
-
Grundy, F.J.1
Henkin, T.M.2
-
15
-
-
0042320361
-
An mRNA structure that controls gene expression by binding S -adenosylmethionine
-
Winkler, W. C.; Nahvi, A.; Sudarsan, N.; Barrick, J. E.; Breaker, R. R. An mRNA structure that controls gene expression by binding S -adenosylmethionine Nat. Struct. Biol. 2003, 10, 701-707
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 701-707
-
-
Winkler, W.C.1
Nahvi, A.2
Sudarsan, N.3
Barrick, J.E.4
Breaker, R.R.5
-
16
-
-
32044442926
-
Evidence for a second class of S -adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria
-
Corbino, K. A.; Barrick, J. E.; Lim, J.; Welz, R.; Tucker, B. J.; Puskarz, I.; Mandal, M.; Rudnick, N. D.; Breaker, R. R. Evidence for a second class of S -adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria Genome Biol. 2005, 6, R70
-
(2005)
Genome Biol
, vol.6
, pp. R70
-
-
Corbino, K.A.1
Barrick, J.E.2
Lim, J.3
Welz, R.4
Tucker, B.J.5
Puskarz, I.6
Mandal, M.7
Rudnick, N.D.8
Breaker, R.R.9
-
17
-
-
53549089576
-
Crystal structures of the SAM-III/S(MK) riboswitch reveal the SAM-dependent translation inhibition mechanism
-
Lu, C.; Smith, A. M.; Fuchs, R. T.; Ding, F.; Rajashankar, K.; Henkin, T. M.; Ke, A. Crystal structures of the SAM-III/S(MK) riboswitch reveal the SAM-dependent translation inhibition mechanism Nat. Struct. Mol. Biol. 2008, 15, 1076-1083
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 1076-1083
-
-
Lu, C.1
Smith, A.M.2
Fuchs, R.T.3
Ding, F.4
Rajashankar, K.5
Henkin, T.M.6
Ke, A.7
-
18
-
-
70350111141
-
A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria
-
Poiata, E.; Meyer, M. M.; Ames, T. D.; Breaker, R. R. A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria RNA 2009, 15, 2046-2056
-
(2009)
RNA
, vol.15
, pp. 2046-2056
-
-
Poiata, E.1
Meyer, M.M.2
Ames, T.D.3
Breaker, R.R.4
-
19
-
-
0037058920
-
An mRNA structure that controls gene expression by binding FMN
-
Winkler, W. C.; Cohen-Chalamish, S.; Breaker, R. R. An mRNA structure that controls gene expression by binding FMN Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 15908-15913
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 15908-15913
-
-
Winkler, W.C.1
Cohen-Chalamish, S.2
Breaker, R.R.3
-
20
-
-
0242298623
-
An mRNA structure in bacteria that controls gene expression by binding lysine
-
Sudarsan, N.; Wickiser, J. K.; Nakamura, S.; Ebert, M. S.; Breaker, R. R. An mRNA structure in bacteria that controls gene expression by binding lysine Genes Dev. 2003, 17, 2688-2697
-
(2003)
Genes Dev
, vol.17
, pp. 2688-2697
-
-
Sudarsan, N.1
Wickiser, J.K.2
Nakamura, S.3
Ebert, M.S.4
Breaker, R.R.5
-
21
-
-
9244225713
-
Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine
-
Batey, R. T.; Gilbert, S. D.; Montange, R. K. Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine Nature 2004, 432, 411-415
-
(2004)
Nature
, vol.432
, pp. 411-415
-
-
Batey, R.T.1
Gilbert, S.D.2
Montange, R.K.3
-
23
-
-
0842334528
-
Adenine riboswitches and gene activation by disruption of a transcription terminator
-
Mandal, M.; Breaker, R. R. Adenine riboswitches and gene activation by disruption of a transcription terminator Nat. Struct. Mol. Biol. 2004, 11, 29-35
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 29-35
-
-
Mandal, M.1
Breaker, R.R.2
-
24
-
-
77955630859
-
An allosteric self-splicing ribozyme triggered by a bacterial second messenger
-
Lee, E. R.; Baker, J. L.; Weinberg, Z.; Sudarsan, N.; Breaker, R. R. An allosteric self-splicing ribozyme triggered by a bacterial second messenger Science 2010, 329, 845-848
-
(2010)
Science
, vol.329
, pp. 845-848
-
-
Lee, E.R.1
Baker, J.L.2
Weinberg, Z.3
Sudarsan, N.4
Breaker, R.R.5
-
25
-
-
47749152941
-
Riboswitches in eubacteria sense the second messenger cyclic di-GMP
-
Sudarsan, N.; Lee, E. R.; Weinberg, Z.; Moy, R. H.; Kim, J. N.; Link, K. H.; Breaker, R. R. Riboswitches in eubacteria sense the second messenger cyclic di-GMP Science 2008, 321, 411-413
-
(2008)
Science
, vol.321
, pp. 411-413
-
-
Sudarsan, N.1
Lee, E.R.2
Weinberg, Z.3
Moy, R.H.4
Kim, J.N.5
Link, K.H.6
Breaker, R.R.7
-
26
-
-
84887997976
-
Riboswitches in eubacteria sense the second messenger c-di-AMP
-
Nelson, J. W.; Sudarsan, N.; Furukawa, K.; Weinberg, Z.; Wang, J. X.; Breaker, R. R. Riboswitches in eubacteria sense the second messenger c-di-AMP Nat. Chem. Biol. 2013, 9, 834-839
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 834-839
-
-
Nelson, J.W.1
Sudarsan, N.2
Furukawa, K.3
Weinberg, Z.4
Wang, J.X.5
Breaker, R.R.6
-
27
-
-
1642586299
-
Control of gene expression by a natural metabolite-responsive ribozyme
-
Winkler, W. C.; Nahvi, A.; Roth, A.; Collins, J. A.; Breaker, R. R. Control of gene expression by a natural metabolite-responsive ribozyme Nature 2004, 428, 281-286
-
(2004)
Nature
, vol.428
, pp. 281-286
-
-
Winkler, W.C.1
Nahvi, A.2
Roth, A.3
Collins, J.A.4
Breaker, R.R.5
-
28
-
-
34547873145
-
Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline
-
Weinberg, Z.; Barrick, J. E.; Yao, Z.; Roth, A.; Kim, J. N.; Gore, J.; Wang, J. X.; Lee, E. R.; Block, K. F.; Sudarsan, N.; Neph, S.; Tompa, M.; Ruzzo, W. L.; Breaker, R. R. Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline Nucleic Acids Res. 2007, 35, 4809-4819
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 4809-4819
-
-
Weinberg, Z.1
Barrick, J.E.2
Yao, Z.3
Roth, A.4
Kim, J.N.5
Gore, J.6
Wang, J.X.7
Lee, E.R.8
Block, K.F.9
Sudarsan, N.10
Neph, S.11
Tompa, M.12
Ruzzo, W.L.13
Breaker, R.R.14
-
29
-
-
84872543206
-
A decade of riboswitches
-
Serganov, A.; Nudler, E. A decade of riboswitches Cell 2013, 152, 17-24
-
(2013)
Cell
, vol.152
, pp. 17-24
-
-
Serganov, A.1
Nudler, E.2
-
30
-
-
35648974802
-
Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution
-
Buck, J.; Furtig, B.; Noeske, J.; Wohnert, J.; Schwalbe, H. Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 15699-15704
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 15699-15704
-
-
Buck, J.1
Furtig, B.2
Noeske, J.3
Wohnert, J.4
Schwalbe, H.5
-
31
-
-
33748325570
-
Structural basis of glmS ribozyme activation by glucosamine-6-phosphate
-
Klein, D. J.; Ferre-D'Amare, A. R. Structural basis of glmS ribozyme activation by glucosamine-6-phosphate Science 2006, 313, 1752-1756
-
(2006)
Science
, vol.313
, pp. 1752-1756
-
-
Klein, D.J.1
Ferre-D'Amare, A.R.2
-
32
-
-
33846279049
-
Structural investigation of the GlmS ribozyme bound to its catalytic cofactor
-
Cochrane, J. C.; Lipchock, S. V.; Strobel, S. A. Structural investigation of the GlmS ribozyme bound to its catalytic cofactor Chem. Biol. 2007, 14, 97-105
-
(2007)
Chem. Biol.
, vol.14
, pp. 97-105
-
-
Cochrane, J.C.1
Lipchock, S.V.2
Strobel, S.A.3
-
33
-
-
10644250950
-
Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs
-
Serganov, A.; Yuan, Y. R.; Pikovskaya, O.; Polonskaia, A.; Malinina, L.; Phan, A. T.; Hobartner, C.; Micura, R.; Breaker, R. R.; Patel, D. J. Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs Chem. Biol. 2004, 11, 1729-1741
-
(2004)
Chem. Biol.
, vol.11
, pp. 1729-1741
-
-
Serganov, A.1
Yuan, Y.R.2
Pikovskaya, O.3
Polonskaia, A.4
Malinina, L.5
Phan, A.T.6
Hobartner, C.7
Micura, R.8
Breaker, R.R.9
Patel, D.J.10
-
34
-
-
53049094260
-
Crystal structure of the lysine riboswitch regulatory mRNA element
-
Garst, A. D.; Heroux, A.; Rambo, R. P.; Batey, R. T. Crystal structure of the lysine riboswitch regulatory mRNA element J. Biol. Chem. 2008, 283, 22347-22351
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22347-22351
-
-
Garst, A.D.1
Heroux, A.2
Rambo, R.P.3
Batey, R.T.4
-
35
-
-
55249114833
-
Structural insights into amino acid binding and gene control by a lysine riboswitch
-
Serganov, A.; Huang, L.; Patel, D. J. Structural insights into amino acid binding and gene control by a lysine riboswitch Nature 2008, 455, 1263-1267
-
(2008)
Nature
, vol.455
, pp. 1263-1267
-
-
Serganov, A.1
Huang, L.2
Patel, D.J.3
-
36
-
-
33745635350
-
Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch
-
Serganov, A.; Polonskaia, A.; Phan, A. T.; Breaker, R. R.; Patel, D. J. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch Nature 2006, 441, 1167-1171
-
(2006)
Nature
, vol.441
, pp. 1167-1171
-
-
Serganov, A.1
Polonskaia, A.2
Phan, A.T.3
Breaker, R.R.4
Patel, D.J.5
-
37
-
-
33744469562
-
Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand
-
Thore, S.; Leibundgut, M.; Ban, N. Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand Science 2006, 312, 1208-1211
-
(2006)
Science
, vol.312
, pp. 1208-1211
-
-
Thore, S.1
Leibundgut, M.2
Ban, N.3
-
38
-
-
62249156218
-
Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch
-
Serganov, A.; Huang, L. L.; Patel, D. J. Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch Nature 2009, 458, 233-237
-
(2009)
Nature
, vol.458
, pp. 233-237
-
-
Serganov, A.1
Huang, L.L.2
Patel, D.J.3
-
39
-
-
84908063090
-
Themes and variations in riboswitch structure and function
-
Peselis, A.; Serganov, A. Themes and variations in riboswitch structure and function Biochim. Biophys. Acta 2014, 1839, 908-918
-
(2014)
Biochim. Biophys. Acta
, vol.1839
, pp. 908-918
-
-
Peselis, A.1
Serganov, A.2
-
40
-
-
79960487609
-
Carba-sugars activate the glmS-riboswitch of Staphylococcus aureus
-
Lunse, C. E.; Schmidt, M. S.; Wittmann, V.; Mayer, G. Carba-sugars activate the glmS-riboswitch of Staphylococcus aureus ACS Chem. Biol. 2011, 6, 675-678
-
(2011)
ACS Chem. Biol.
, vol.6
, pp. 675-678
-
-
Lunse, C.E.1
Schmidt, M.S.2
Wittmann, V.3
Mayer, G.4
-
41
-
-
84877582071
-
Nucleotides adjacent to the ligand-binding pocket are linked to activity tuning in the purine riboswitch
-
Stoddard, C. D.; Widmann, J.; Trausch, J. J.; Marcano-Velazquez, J. G.; Knight, R.; Batey, R. T. Nucleotides adjacent to the ligand-binding pocket are linked to activity tuning in the purine riboswitch J. Mol. Biol. 2013, 425, 1596-1611
-
(2013)
J. Mol. Biol.
, vol.425
, pp. 1596-1611
-
-
Stoddard, C.D.1
Widmann, J.2
Trausch, J.J.3
Marcano-Velazquez, J.G.4
Knight, R.5
Batey, R.T.6
-
42
-
-
71449108155
-
Structural basis of ligand binding by a c-di-GMP riboswitch
-
Smith, K. D.; Lipchock, S. V.; Ames, T. D.; Wang, J.; Breaker, R. R.; Strobel, S. A. Structural basis of ligand binding by a c-di-GMP riboswitch Nat. Struct. Mol. Biol. 2009, 16, 1218-1223
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1218-1223
-
-
Smith, K.D.1
Lipchock, S.V.2
Ames, T.D.3
Wang, J.4
Breaker, R.R.5
Strobel, S.A.6
-
43
-
-
80053311154
-
Differential analogue binding by two classes of c-di-GMP riboswitches
-
Shanahan, C. A.; Gaffney, B. L.; Jones, R. A.; Strobel, S. A. Differential analogue binding by two classes of c-di-GMP riboswitches J. Am. Chem. Soc. 2011, 133, 15578-15592
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 15578-15592
-
-
Shanahan, C.A.1
Gaffney, B.L.2
Jones, R.A.3
Strobel, S.A.4
-
44
-
-
72149126118
-
A switch in time: detailing the life of a riboswitch
-
Garst, A. D.; Batey, R. T. A switch in time: detailing the life of a riboswitch Biochim. Biophys. Acta 2009, 1789, 584-591
-
(2009)
Biochim. Biophys. Acta
, vol.1789
, pp. 584-591
-
-
Garst, A.D.1
Batey, R.T.2
-
45
-
-
84908067664
-
The purine riboswitch as a model system for exploring RNA biology and chemistry
-
Porter, E. B.; Marcano-Velazquez, J. G.; Batey, R. T. The purine riboswitch as a model system for exploring RNA biology and chemistry Biochim. Biophys. Acta 2014, 1839, 919-930
-
(2014)
Biochim. Biophys. Acta
, vol.1839
, pp. 919-930
-
-
Porter, E.B.1
Marcano-Velazquez, J.G.2
Batey, R.T.3
-
46
-
-
33645752732
-
High-throughput-compatible assay for glmS riboswitch metabolite dependence
-
Mayer, G.; Famulok, M. High-throughput-compatible assay for glmS riboswitch metabolite dependence ChemBioChem 2006, 7, 602-604
-
(2006)
ChemBioChem
, vol.7
, pp. 602-604
-
-
Mayer, G.1
Famulok, M.2
-
47
-
-
33748923106
-
Development and application of a high-throughput assay for glmS riboswitch activators
-
Blount, K.; Puskarz, I.; Penchovsky, R.; Breaker, R. Development and application of a high-throughput assay for glmS riboswitch activators RNA Biol. 2006, 3, 77-81
-
(2006)
RNA Biol
, vol.3
, pp. 77-81
-
-
Blount, K.1
Puskarz, I.2
Penchovsky, R.3
Breaker, R.4
-
48
-
-
79953174439
-
Fragment screening against the thiamine pyrophosphate riboswitch thiM
-
Cressina, E.; Chen, L. H.; Abell, C.; Leeper, F. J.; Smith, A. G. Fragment screening against the thiamine pyrophosphate riboswitch thiM Chem. Sci. 2011, 2, 157-165
-
(2011)
Chem. Sci.
, vol.2
, pp. 157-165
-
-
Cressina, E.1
Chen, L.H.2
Abell, C.3
Leeper, F.J.4
Smith, A.G.5
-
49
-
-
84863925231
-
Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues
-
Chen, L.; Cressina, E.; Dixon, N.; Erixon, K.; Agyei-Owusu, K.; Micklefield, J.; Smith, A. G.; Abell, C.; Leeper, F. J. Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues Org. Biomol. Chem. 2012, 10, 5924-5931
-
(2012)
Org. Biomol. Chem.
, vol.10
, pp. 5924-5931
-
-
Chen, L.1
Cressina, E.2
Dixon, N.3
Erixon, K.4
Agyei-Owusu, K.5
Micklefield, J.6
Smith, A.G.7
Abell, C.8
Leeper, F.J.9
-
50
-
-
77149165421
-
Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis
-
Baird, N. J.; Ferre-D'Amare, A. R. Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis RNA 2010, 16, 598-609
-
(2010)
RNA
, vol.16
, pp. 598-609
-
-
Baird, N.J.1
Ferre-D'Amare, A.R.2
-
51
-
-
84860160810
-
Multiple conformations of SAM-II riboswitch detected with SAXS and NMR spectroscopy
-
Chen, B.; Zuo, X.; Wang, Y. X.; Dayie, T. K. Multiple conformations of SAM-II riboswitch detected with SAXS and NMR spectroscopy Nucleic Acids Res. 2012, 40, 3117-3130
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 3117-3130
-
-
Chen, B.1
Zuo, X.2
Wang, Y.X.3
Dayie, T.K.4
-
52
-
-
13444271576
-
An intermolecular base triple as the basis of ligand specificity and affinity in the guanine- and adenine-sensing riboswitch RNAs
-
Noeske, J.; Richter, C.; Grundl, M. A.; Nasiri, H. R.; Schwalbe, H.; Wohnert, J. An intermolecular base triple as the basis of ligand specificity and affinity in the guanine- and adenine-sensing riboswitch RNAs Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 1372-1377
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 1372-1377
-
-
Noeske, J.1
Richter, C.2
Grundl, M.A.3
Nasiri, H.R.4
Schwalbe, H.5
Wohnert, J.6
-
53
-
-
17144452674
-
NMR spectroscopy of RNA
-
Furtig, B.; Richter, C.; Wohnert, J.; Schwalbe, H. NMR spectroscopy of RNA ChemBioChem 2003, 4, 936-962
-
(2003)
ChemBioChem
, vol.4
, pp. 936-962
-
-
Furtig, B.1
Richter, C.2
Wohnert, J.3
Schwalbe, H.4
-
54
-
-
28844492215
-
Thiamine pyrophosphate riboswitches are targets for the antimicrobial compound pyrithiamine
-
Sudarsan, N.; Cohen-Chalamish, S.; Nakamura, S.; Emilsson, G. M.; Breaker, R. R. Thiamine pyrophosphate riboswitches are targets for the antimicrobial compound pyrithiamine Chem. Biol. 2005, 12, 1325-1335
-
(2005)
Chem. Biol.
, vol.12
, pp. 1325-1335
-
-
Sudarsan, N.1
Cohen-Chalamish, S.2
Nakamura, S.3
Emilsson, G.M.4
Breaker, R.R.5
-
55
-
-
33845710324
-
Antibacterial lysine analogs that target lysine riboswitches
-
Blount, K. F.; Wang, J. X.; Lim, J.; Sudarsan, N.; Breaker, R. R. Antibacterial lysine analogs that target lysine riboswitches Nat. Chem. Biol. 2007, 3, 44-49
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 44-49
-
-
Blount, K.F.1
Wang, J.X.2
Lim, J.3
Sudarsan, N.4
Breaker, R.R.5
-
56
-
-
77954079519
-
Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways
-
Mulhbacher, J.; Brouillette, E.; Allard, M.; Fortier, L. C.; Malouin, F.; Lafontaine, D. A. Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways PLoS Pathog. 2010, 6, e1000865
-
(2010)
PLoS Pathog
, vol.6
-
-
Mulhbacher, J.1
Brouillette, E.2
Allard, M.3
Fortier, L.C.4
Malouin, F.5
Lafontaine, D.A.6
-
57
-
-
84897060734
-
Structure-guided design of fluorescent S -adenosylmethionine analogs for a high-throughput screen to target SAM-I riboswitch RNAs
-
Hickey, S. F.; Hammond, M. C. Structure-guided design of fluorescent S -adenosylmethionine analogs for a high-throughput screen to target SAM-I riboswitch RNAs Chem. Biol. 2014, 21, 345-356
-
(2014)
Chem. Biol.
, vol.21
, pp. 345-356
-
-
Hickey, S.F.1
Hammond, M.C.2
-
58
-
-
84865275166
-
Identification of ligand analogues that control c-di-GMP riboswitches
-
Furukawa, R.; Gu, H. Z.; Sudarsan, N.; Hayakawa, Y.; Hyodo, M.; Breaker, R. R. Identification of ligand analogues that control c-di-GMP riboswitches ACS Chem. Biol. 2012, 7, 1436-1443
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 1436-1443
-
-
Furukawa, R.1
Gu, H.Z.2
Sudarsan, N.3
Hayakawa, Y.4
Hyodo, M.5
Breaker, R.R.6
-
59
-
-
0034708334
-
Structure and function of the hairpin ribozyme
-
Fedor, M. J. Structure and function of the hairpin ribozyme J. Mol. Biol. 2000, 297, 269-291
-
(2000)
J. Mol. Biol.
, vol.297
, pp. 269-291
-
-
Fedor, M.J.1
-
60
-
-
33847207834
-
Molecular similarity analysis in virtual screening: foundations, limitations and novel approaches
-
Eckert, H.; Bajorath, J. Molecular similarity analysis in virtual screening: foundations, limitations and novel approaches Drug Discovery Today 2007, 12, 225-233
-
(2007)
Drug Discovery Today
, vol.12
, pp. 225-233
-
-
Eckert, H.1
Bajorath, J.2
-
61
-
-
80052982281
-
The dynamic nature of RNA as key to understanding riboswitch mechanisms
-
Haller, A.; Souliere, M. F.; Micura, R. The dynamic nature of RNA as key to understanding riboswitch mechanisms Acc. Chem. Res. 2011, 44, 1339-1348
-
(2011)
Acc. Chem. Res.
, vol.44
, pp. 1339-1348
-
-
Haller, A.1
Souliere, M.F.2
Micura, R.3
-
62
-
-
78049276834
-
Ribozymes and riboswitches: modulation of RNA function by small molecules
-
Zhang, J.; Lau, M. W.; Ferre-D'Amare, A. R. Ribozymes and riboswitches: modulation of RNA function by small molecules Biochemistry 2010, 49, 9123-9131
-
(2010)
Biochemistry
, vol.49
, pp. 9123-9131
-
-
Zhang, J.1
Lau, M.W.2
Ferre-D'Amare, A.R.3
-
63
-
-
84878559511
-
Fluorescence monitoring of riboswitch transcription regulation using a dual molecular beacon assay
-
Chinnappan, R.; Dube, A.; Lemay, J. F.; Lafontaine, D. A. Fluorescence monitoring of riboswitch transcription regulation using a dual molecular beacon assay Nucleic Acids Res. 2013, 41, e106
-
(2013)
Nucleic Acids Res
, vol.41
, pp. e106
-
-
Chinnappan, R.1
Dube, A.2
Lemay, J.F.3
Lafontaine, D.A.4
-
64
-
-
46849089254
-
Recent developments in fragment-based drug discovery
-
Congreve, M.; Chessari, G.; Tisi, D.; Woodhead, A. J. Recent developments in fragment-based drug discovery J. Med. Chem. 2008, 51, 3661-3680
-
(2008)
J. Med. Chem.
, vol.51
, pp. 3661-3680
-
-
Congreve, M.1
Chessari, G.2
Tisi, D.3
Woodhead, A.J.4
-
65
-
-
0035324944
-
Molecular complexity and its impact on the probability of finding leads for drug discovery
-
Hann, M. M.; Leach, A. R.; Harper, G. Molecular complexity and its impact on the probability of finding leads for drug discovery J. Chem. Inf. Model. 2001, 41, 856-864
-
(2001)
J. Chem. Inf. Model.
, vol.41
, pp. 856-864
-
-
Hann, M.M.1
Leach, A.R.2
Harper, G.3
-
66
-
-
77951137401
-
A fragment-based approach to identifying ligands for riboswitches
-
Chen, L.; Cressina, E.; Leeper, F. J.; Smith, A. G.; Abell, C. A fragment-based approach to identifying ligands for riboswitches ACS Chem. Biol. 2010, 5, 355-358
-
(2010)
ACS Chem. Biol.
, vol.5
, pp. 355-358
-
-
Chen, L.1
Cressina, E.2
Leeper, F.J.3
Smith, A.G.4
Abell, C.5
-
67
-
-
23844497441
-
Biophysical tools to monitor enzyme-ligand interactions of enzymes involved in vitamin biosynthesis
-
Ciulli, A.; Abell, C. Biophysical tools to monitor enzyme-ligand interactions of enzymes involved in vitamin biosynthesis Biochem. Soc. Trans. 2005, 33, 767-771
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 767-771
-
-
Ciulli, A.1
Abell, C.2
-
68
-
-
84901406647
-
Validating fragment-based drug discovery for biological RNAs: lead fragments bind and remodel the TPP riboswitch specifically
-
Warner, K. D.; Homan, P.; Weeks, K. M.; Smith, A. G.; Abell, C.; Ferre-D'Amare, A. R. Validating fragment-based drug discovery for biological RNAs: lead fragments bind and remodel the TPP riboswitch specifically Chem. Biol. 2014, 21, 591-595
-
(2014)
Chem. Biol.
, vol.21
, pp. 591-595
-
-
Warner, K.D.1
Homan, P.2
Weeks, K.M.3
Smith, A.G.4
Abell, C.5
Ferre-D'Amare, A.R.6
-
69
-
-
79951676664
-
The glmS ribozyme: use of a small molecule coenzyme by a gene-regulatory RNA
-
Ferre-D'Amare, A. R. The glmS ribozyme: use of a small molecule coenzyme by a gene-regulatory RNA Q. Rev. Biophys. 2010, 43, 423-447
-
(2010)
Q. Rev. Biophys.
, vol.43
, pp. 423-447
-
-
Ferre-D'Amare, A.R.1
-
70
-
-
73449116019
-
Design and antimicrobial action of purine analogues that bind guanine riboswitches
-
Kim, J. N.; Blount, K. F.; Puskarz, I.; Lim, J.; Link, K. H.; Breaker, R. R. Design and antimicrobial action of purine analogues that bind guanine riboswitches ACS Chem. Biol. 2009, 4, 915-927
-
(2009)
ACS Chem. Biol.
, vol.4
, pp. 915-927
-
-
Kim, J.N.1
Blount, K.F.2
Puskarz, I.3
Lim, J.4
Link, K.H.5
Breaker, R.R.6
-
71
-
-
33750149294
-
Characteristics of ligand recognition by a glmS self-cleaving ribozyme
-
Lim, J.; Grove, B. C.; Roth, A.; Breaker, R. R. Characteristics of ligand recognition by a glmS self-cleaving ribozyme Angew. Chem., Int. Ed. 2006, 45, 6689-6693
-
(2006)
Angew. Chem., Int. Ed.
, vol.45
, pp. 6689-6693
-
-
Lim, J.1
Grove, B.C.2
Roth, A.3
Breaker, R.R.4
-
72
-
-
27744525243
-
Ligand requirements for glmS ribozyme self-cleavage
-
McCarthy, T. J.; Plog, M. A.; Floy, S. A.; Jansen, J. A.; Soukup, J. K.; Soukup, G. A. Ligand requirements for glmS ribozyme self-cleavage Chem. Biol. 2005, 12, 1221-1226
-
(2005)
Chem. Biol.
, vol.12
, pp. 1221-1226
-
-
McCarthy, T.J.1
Plog, M.A.2
Floy, S.A.3
Jansen, J.A.4
Soukup, J.K.5
Soukup, G.A.6
-
73
-
-
77951236405
-
Riboswitch structure: an internal residue mimicking the purine ligand
-
Delfosse, V.; Bouchard, P.; Bonneau, E.; Dagenais, P.; Lemay, J. F.; Lafontaine, D. A.; Legault, P. Riboswitch structure: an internal residue mimicking the purine ligand Nucleic Acids Res. 2010, 38, 2057-2068
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 2057-2068
-
-
Delfosse, V.1
Bouchard, P.2
Bonneau, E.3
Dagenais, P.4
Lemay, J.F.5
Lafontaine, D.A.6
Legault, P.7
-
74
-
-
80052967464
-
Structural principles of nucleoside selectivity in a 2′-deoxyguanosine riboswitch
-
Pikovskaya, O.; Polonskaia, A.; Patel, D. J.; Serganov, A. Structural principles of nucleoside selectivity in a 2′-deoxyguanosine riboswitch Nat. Chem. Biol. 2011, 7, 748-755
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 748-755
-
-
Pikovskaya, O.1
Polonskaia, A.2
Patel, D.J.3
Serganov, A.4
-
75
-
-
15944382675
-
The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch
-
Wickiser, J. K.; Winkler, W. C.; Breaker, R. R.; Crothers, D. M. The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch Mol. Cell 2005, 18, 49-60
-
(2005)
Mol. Cell
, vol.18
, pp. 49-60
-
-
Wickiser, J.K.1
Winkler, W.C.2
Breaker, R.R.3
Crothers, D.M.4
-
76
-
-
0038210214
-
Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria
-
Mandal, M.; Boese, B.; Barrick, J. E.; Winkler, W. C.; Breaker, R. R. Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria Cell 2003, 113, 577-586
-
(2003)
Cell
, vol.113
, pp. 577-586
-
-
Mandal, M.1
Boese, B.2
Barrick, J.E.3
Winkler, W.C.4
Breaker, R.R.5
-
77
-
-
0031882942
-
Regulation of riboflavin biosynthesis in Bacillus subtilis is affected by the activity of the flavokinase/flavin adenine dinucleotide synthetase encoded by ribC
-
Mack, M.; van Loon, A. P.; Hohmann, H. P. Regulation of riboflavin biosynthesis in Bacillus subtilis is affected by the activity of the flavokinase/flavin adenine dinucleotide synthetase encoded by ribC J. Bacteriol. 1998, 180, 950-955
-
(1998)
J. Bacteriol.
, vol.180
, pp. 950-955
-
-
Mack, M.1
Van Loon, A.P.2
Hohmann, H.P.3
-
78
-
-
85011936077
-
Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression
-
Lee, E. R.; Blount, K. F.; Breaker, R. R. Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression RNA Biol. 2009, 6, 187-194
-
(2009)
RNA Biol
, vol.6
, pp. 187-194
-
-
Lee, E.R.1
Blount, K.F.2
Breaker, R.R.3
-
79
-
-
84872678577
-
Experimental treatment of Staphylococcus aureus bovine intramammary infection using a guanine riboswitch ligand analog
-
Ster, C.; Allard, M.; Boulanger, S.; Lamontagne Boulet, M.; Mulhbacher, J.; Lafontaine, D. A.; Marsault, E.; Lacasse, P.; Malouin, F. Experimental treatment of Staphylococcus aureus bovine intramammary infection using a guanine riboswitch ligand analog J. Dairy Sci. 2013, 96, 1000-1008
-
(2013)
J. Dairy Sci.
, vol.96
, pp. 1000-1008
-
-
Ster, C.1
Allard, M.2
Boulanger, S.3
Lamontagne Boulet, M.4
Mulhbacher, J.5
Lafontaine, D.A.6
Marsault, E.7
Lacasse, P.8
Malouin, F.9
-
80
-
-
0000396592
-
Pyrimidopteridines by oxidative self-condensation of aminopyrimidines
-
Taylor, E. C.; Loux, H. M.; Falco, E. A.; Hitchings, G. H. Pyrimidopteridines by oxidative self-condensation of aminopyrimidines J. Am. Chem. Soc. 1955, 77, 2243-2248
-
(1955)
J. Am. Chem. Soc.
, vol.77
, pp. 2243-2248
-
-
Taylor, E.C.1
Loux, H.M.2
Falco, E.A.3
Hitchings, G.H.4
-
81
-
-
84866735022
-
Compound instability in dimethyl sulphoxide, case studies with 5-aminopyrimidines and the implications for compound storage and screening
-
Prochazkova, E.; Jansa, P.; Brezinova, A.; Cechova, L.; Mertlikova-Kaiserova, H.; Holy, A.; Dracinsky, M. Compound instability in dimethyl sulphoxide, case studies with 5-aminopyrimidines and the implications for compound storage and screening Bioorg. Med. Chem. Lett. 2012, 22, 6405-6409
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 6405-6409
-
-
Prochazkova, E.1
Jansa, P.2
Brezinova, A.3
Cechova, L.4
Mertlikova-Kaiserova, H.5
Holy, A.6
Dracinsky, M.7
-
82
-
-
78650512644
-
Synthesis and in vitro evaluation of 2-amino-4- N -piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agents
-
De Jonghe, S.; Marchand, A.; Gao, L. J.; Calleja, A.; Cuveliers, E.; Sienaert, I.; Herman, J.; Clydesdale, G.; Sefrioui, H.; Lin, Y. A.; Pfleiderer, W.; Waer, M.; Herdewijn, P. Synthesis and in vitro evaluation of 2-amino-4- N -piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agents Bioorg. Med. Chem. Lett. 2011, 21, 145-149
-
(2011)
Bioorg. Med. Chem. Lett.
, vol.21
, pp. 145-149
-
-
De Jonghe, S.1
Marchand, A.2
Gao, L.J.3
Calleja, A.4
Cuveliers, E.5
Sienaert, I.6
Herman, J.7
Clydesdale, G.8
Sefrioui, H.9
Lin, Y.A.10
Pfleiderer, W.11
Waer, M.12
Herdewijn, P.13
-
83
-
-
38649084104
-
Mechanisms of resistance to an amino acid antibiotic that targets translation
-
Ataide, S. F.; Wilson, S. N.; Dang, S.; Rogers, T. E.; Roy, B.; Banerjee, R.; Henkin, T. M.; Ibba, M. Mechanisms of resistance to an amino acid antibiotic that targets translation ACS Chem. Biol. 2007, 2, 819-827
-
(2007)
ACS Chem. Biol.
, vol.2
, pp. 819-827
-
-
Ataide, S.F.1
Wilson, S.N.2
Dang, S.3
Rogers, T.E.4
Roy, B.5
Banerjee, R.6
Henkin, T.M.7
Ibba, M.8
-
84
-
-
84892514964
-
The promise of riboswitches as potential antibacterial drug targets
-
Lunse, C. E.; Schuller, A.; Mayer, G. The promise of riboswitches as potential antibacterial drug targets Int. J. Med. Microbiol. 2014, 304, 79-92
-
(2014)
Int. J. Med. Microbiol.
, vol.304
, pp. 79-92
-
-
Lunse, C.E.1
Schuller, A.2
Mayer, G.3
-
85
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
Ellington, A. D.; Szostak, J. W. In vitro selection of RNA molecules that bind specific ligands Nature 1990, 346, 818-822
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
86
-
-
0028874701
-
Structural probing and damage selection of citrulline- and arginine-specific RNA aptamers identify base positions required for binding
-
Burgstaller, P.; Kochoyan, M.; Famulok, M. Structural probing and damage selection of citrulline- and arginine-specific RNA aptamers identify base positions required for binding Nucleic Acids Res. 1995, 23, 4769-4776
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 4769-4776
-
-
Burgstaller, P.1
Kochoyan, M.2
Famulok, M.3
-
87
-
-
38649141203
-
Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides
-
Rentmeister, A.; Mayer, G.; Kuhn, N.; Famulok, M. Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides Biol. Chem. 2008, 389, 127-134
-
(2008)
Biol. Chem.
, vol.389
, pp. 127-134
-
-
Rentmeister, A.1
Mayer, G.2
Kuhn, N.3
Famulok, M.4
-
88
-
-
33846526795
-
RNA ligands that distinguish metabolite-induced conformations in the TPP riboswitch
-
Mayer, G.; Raddatz, M. S. L.; Grunwald, J. D.; Famulok, M. RNA ligands that distinguish metabolite-induced conformations in the TPP riboswitch Angew. Chem., Int. Ed. 2007, 46, 557-560
-
(2007)
Angew. Chem., Int. Ed.
, vol.46
, pp. 557-560
-
-
Mayer, G.1
Raddatz, M.S.L.2
Grunwald, J.D.3
Famulok, M.4
-
89
-
-
34547116896
-
Conformational changes in the expression domain of the Escherichia coli thiM riboswitch
-
Rentmeister, A.; Mayer, G.; Kuhn, N.; Famulok, M. Conformational changes in the expression domain of the Escherichia coli thiM riboswitch Nucleic Acids Res. 2007, 35, 3713-3722
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 3713-3722
-
-
Rentmeister, A.1
Mayer, G.2
Kuhn, N.3
Famulok, M.4
-
90
-
-
70349556310
-
A RNA-based approach towards small-molecule inhibitors
-
Mayer, G.; Faulhammer, D.; Grattinger, M.; Fessele, S.; Blind, M. A RNA-based approach towards small-molecule inhibitors ChemBioChem 2009, 10, 1993-1996
-
(2009)
ChemBioChem
, vol.10
, pp. 1993-1996
-
-
Mayer, G.1
Faulhammer, D.2
Grattinger, M.3
Fessele, S.4
Blind, M.5
-
91
-
-
0027370433
-
Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production
-
Zapp, M. L.; Stern, S.; Green, M. R. Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production Cell 1993, 74, 969-978
-
(1993)
Cell
, vol.74
, pp. 969-978
-
-
Zapp, M.L.1
Stern, S.2
Green, M.R.3
-
92
-
-
0029294539
-
Specific binding of aminoglycoside antibiotics to RNA
-
Wang, Y.; Rando, R. R. Specific binding of aminoglycoside antibiotics to RNA Chem. Biol. 1995, 2, 281-290
-
(1995)
Chem. Biol.
, vol.2
, pp. 281-290
-
-
Wang, Y.1
Rando, R.R.2
-
93
-
-
0142106950
-
RNA as a drug target: the case of aminoglycosides
-
Vicens, Q.; Westhof, E. RNA as a drug target: the case of aminoglycosides ChemBioChem 2003, 4, 1018-1023
-
(2003)
ChemBioChem
, vol.4
, pp. 1018-1023
-
-
Vicens, Q.1
Westhof, E.2
-
94
-
-
0034602848
-
Modulation of RNA function by aminoglycoside antibiotics
-
Schroeder, R.; Waldsich, C.; Wank, H. Modulation of RNA function by aminoglycoside antibiotics EMBO J. 2000, 19, 1-9
-
(2000)
EMBO J.
, vol.19
, pp. 1-9
-
-
Schroeder, R.1
Waldsich, C.2
Wank, H.3
-
95
-
-
84878064545
-
Glucosamine and glucosamine-6-phosphate derivatives: catalytic cofactor analogues for the glmS ribozyme
-
Posakony, J. J.; Ferre-D'Amare, A. R. Glucosamine and glucosamine-6-phosphate derivatives: catalytic cofactor analogues for the glmS ribozyme J. Org. Chem. 2013, 78, 4730-4743
-
(2013)
J. Org. Chem.
, vol.78
, pp. 4730-4743
-
-
Posakony, J.J.1
Ferre-D'Amare, A.R.2
-
96
-
-
84864185753
-
Pseudoknot preorganization of the preQ1 class I riboswitch
-
Santner, T.; Rieder, U.; Kreutz, C.; Micura, R. Pseudoknot preorganization of the preQ1 class I riboswitch J. Am. Chem. Soc. 2012, 134, 11928-11931
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 11928-11931
-
-
Santner, T.1
Rieder, U.2
Kreutz, C.3
Micura, R.4
-
97
-
-
84892883074
-
Probing riboswitch binding sites with molecular docking, focused libraries, and in-line probing assays
-
Colizzi, F.; Lamontagne, A. M.; Lafontaine, D. A.; Bussi, G. Probing riboswitch binding sites with molecular docking, focused libraries, and in-line probing assays Methods Mol. Biol. 2014, 1103, 141-151
-
(2014)
Methods Mol. Biol.
, vol.1103
, pp. 141-151
-
-
Colizzi, F.1
Lamontagne, A.M.2
Lafontaine, D.A.3
Bussi, G.4
-
98
-
-
84987606101
-
Novel TPP-riboswitch activators bypass metabolic enzyme dependency
-
Lunse, C. E.; Scott, F. J.; Suckling, C. J.; Mayer, G. Novel TPP-riboswitch activators bypass metabolic enzyme dependency Front. Chem. (Lausanne, Switz.) 2014, 2, 53
-
(2014)
Front. Chem. (Lausanne, Switz.)
, vol.2
, pp. 53
-
-
Lunse, C.E.1
Scott, F.J.2
Suckling, C.J.3
Mayer, G.4
-
99
-
-
33847148935
-
Inhibition of pyruvate decarboxylase from Z. mobilis by novel analogues of thiamine pyrophosphate: investigating pyrophosphate mimics
-
Erixon, K. M.; Dabalos, C. L.; Leeper, F. J. Inhibition of pyruvate decarboxylase from Z. mobilis by novel analogues of thiamine pyrophosphate: investigating pyrophosphate mimics Chem. Commun. 2007, 960-962
-
(2007)
Chem. Commun.
, pp. 960-962
-
-
Erixon, K.M.1
Dabalos, C.L.2
Leeper, F.J.3
-
100
-
-
52149122744
-
Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold
-
Erixon, K. M.; Dabalos, C. L.; Leeper, F. J. Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold Org. Biomol. Chem. 2008, 6, 3561-3572
-
(2008)
Org. Biomol. Chem.
, vol.6
, pp. 3561-3572
-
-
Erixon, K.M.1
Dabalos, C.L.2
Leeper, F.J.3
-
101
-
-
84919615317
-
Phosphatase-inert glucosamine 6-phosphate mimics serve as actuators of the glmS riboswitch
-
Fei, X.; Holmes, T.; Diddle, J.; Hintz, L.; Delaney, D.; Stock, A.; Renner, D.; McDevitt, M.; Berkowitz, D. B.; Soukup, J. K. Phosphatase-inert glucosamine 6-phosphate mimics serve as actuators of the glmS riboswitch ACS Chem. Biol. 2014, 9, 2875-2882
-
(2014)
ACS Chem. Biol.
, vol.9
, pp. 2875-2882
-
-
Fei, X.1
Holmes, T.2
Diddle, J.3
Hintz, L.4
Delaney, D.5
Stock, A.6
Renner, D.7
McDevitt, M.8
Berkowitz, D.B.9
Soukup, J.K.10
-
102
-
-
67650474303
-
The RFN riboswitch of Bacillus subtilis is a target for the antibiotic roseoflavin produced by Streptomyces davawensis
-
Ott, E.; Stolz, J.; Lehmann, M.; Mack, M. The RFN riboswitch of Bacillus subtilis is a target for the antibiotic roseoflavin produced by Streptomyces davawensis RNA Biol. 2009, 6, 276-280
-
(2009)
RNA Biol
, vol.6
, pp. 276-280
-
-
Ott, E.1
Stolz, J.2
Lehmann, M.3
Mack, M.4
-
103
-
-
84866891749
-
A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis
-
Pedrolli, D. B.; Matern, A.; Wang, J.; Ester, M.; Siedler, K.; Breaker, R.; Mack, M. A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis Nucleic Acids Res. 2012, 40, 8662-8673
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 8662-8673
-
-
Pedrolli, D.B.1
Matern, A.2
Wang, J.3
Ester, M.4
Siedler, K.5
Breaker, R.6
Mack, M.7
|