Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues

Organic and Biomolecular Chemistry

Volumn 10, Issue 30, 2012, Pages 5924-5931

  Chen, Liuhong ^a   Cressina, Elena ^a   Dixon, Neil ^b   Erixon, Karl ^a   Agyei Owusu, Kwasi ^a   Micklefield, Jason ^b   Smith, Alison G ^a   Abell, Chris ^a   Leeper, Finian J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPYRIMIDINES; BINDING AFFINITIES; DONOR AND ACCEPTOR; ELECTRON-WITHDRAWING EFFECTS; H-BONDING; IN-VIVO; LIGAND RECOGNITION; NANOMOLAR; NATURAL LIGANDS; PHOSPHATE ESTERS; PYRIMIDINE RING; RIBOSWITCHES; SMALL MOLECULES; SPECIFIC CONTACT; STACKING INTERACTION; THIAMINE DIPHOSPHATES;

AROMATIC COMPOUNDS; BINDING ENERGY; ESCHERICHIA COLI; GENE EXPRESSION;

LIGANDS;

APTAMER; BACTERIAL RNA; COCARBOXYLASE; LIGAND; PYRIMIDINE; PYRIMIDINE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; METABOLISM; RIBOSWITCH; STRUCTURE ACTIVITY RELATION;

APTAMERS, NUCLEOTIDE; ESCHERICHIA COLI; GENE EXPRESSION; LIGANDS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PYRIMIDINES; RIBOSWITCH; RNA, BACTERIAL; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THIAMINE PYROPHOSPHATE;

ESCHERICHIA COLI;

EID: 84863925231     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c2ob07116a     Document Type: Article

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