Design and antimicrobial action of purine analogues that bind guanine riboswitches

ACS Chemical Biology

Volumn 4, Issue 11, 2009, Pages 915-927

  Kim, Jane N ^a   Blount, Kenneth F ^a,c   Puskarz, Izabela ^a,c   Lim, Jinsoo ^a,d   Link, Kristian H ^a,b   Breaker, Ronald R ^a,b  

^a YALE UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c BioRelix Inc   (United States)

^d Idenix Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 N HYDROXYADENINE; ANTIINFECTIVE AGENT; APTAMER; GUANINE; GUANINE DERIVATIVE; PURINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL GROWTH; BACTERIAL STRAIN; BINDING AFFINITY; CONTROLLED STUDY; DRUG DESIGN; DRUG INHIBITION; DRUG MECHANISM; GENE EXPRESSION; GENE REPRESSION; GROWTH INHIBITION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RIBOSWITCH;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BASE SEQUENCE; DRUG DESIGN; GUANINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; REGULATORY SEQUENCES, RIBONUCLEIC ACID; RNA, BACTERIAL;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); POSIBACTERIA;

EID: 73449116019     PISSN: 15548929     EISSN: None     Source Type: Journal    
DOI: 10.1021/cb900146k     Document Type: Article

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