Probing riboswitch binding sites with molecular docking, focused libraries, and in-line probing assays

Methods in Molecular Biology

Volumn 1103, Issue , 2014, Pages 141-151

  Colizzi, Francesco ^a   Lamontagne, Anne Marie ^b   Lafontaine, Daniel A ^b   Bussi, Giovanni ^a  

^a SISSA   (Italy)

^b UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Docking; Focused library; In line probing; Ligand design; Structure activity relationship (SAR); Structure based; Virtual screening

Indexed keywords

HYPOXANTHINE; LIGAND; RNA;

ARTICLE; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; GENETIC ALGORITHM; HYDROGEN BOND; MOLECULAR DOCKING; NONHUMAN; PH; PRIORITY JOURNAL; PROTON TRANSPORT; RIBOSWITCH; STRUCTURE ACTIVITY RELATION; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; GENETICS; METHODOLOGY; MOLECULAR BIOLOGY; BIOLOGICAL ACTIVITY;

BINDING SITES; COMPUTER SIMULATION; LIGANDS; MOLECULAR BIOLOGY; MOLECULAR DOCKING SIMULATION; NUCLEIC ACID CONFORMATION; RIBOSWITCH; RNA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84892883074     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-730-3_11     Document Type: Article

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