Targeting connexin 43 with α-connexin carboxyl-terminal (ACT1) peptide enhances the activity of the targeted inhibitors, tamoxifen and lapatinib, in breast cancer: Clinical implication for ACT1

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Grek, Christina L ^a   Rhett, Joshua Matthew ^b   Bruce, Jaclynn S ^b   Abt, Melissa A ^b   Ghatnekar, Gautam S ^a   Yeh, Elizabeth S ^b  

^a FirstString Research Inc   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

ACT1 peptide; Breast cancer; Cancer therapeutic; Connexin43; Gap junction intercellular communication; Lapatinib; Tamoxifen

Indexed keywords

ALPHA CONNEXIN; CONNEXIN 43; GAP JUNCTION PROTEIN; LAPATINIB; PEPTIDE; TAMOXIFEN CITRATE; TYPE 1 CARBOXYL TERMINAL PEPTIDE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; GJA1 PROTEIN, HUMAN; QUINAZOLINE DERIVATIVE; TAMOXIFEN; TRAF3IP2 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR;

ARTICLE; BREAST CANCER CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; GAP JUNCTION; HUMAN; HUMAN CELL; PROTEIN TARGETING; BREAST TUMOR; DRUG DELIVERY SYSTEM; FEMALE; METABOLISM; PROCEDURES; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CONNEXIN 43; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; QUINAZOLINES; TAMOXIFEN; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS;

EID: 84928253795     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1229-6     Document Type: Article

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