Connexin43 pseudogene is expressed in tumor cells and inhibits growth

Oncogene

Volumn 23, Issue 27, 2004, Pages 4763-4770

  Kandouz, Mustapha ^a   Bier, Andrew ^a   Carystinos, George D ^a   Alaoui Jamali, Moulay A ^a   Batist, Gerald ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Cancer; Connexin43; Pseudogene; Transcription; Translation

Indexed keywords

CONNEXIN 43; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; MESSENGER RNA;

ANIMAL CELL; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL CULTURE; CANCER INHIBITION; CELL COMMUNICATION; CELL STRAIN MCF 7; COLONY FORMING UNIT; CONTROLLED STUDY; GAP JUNCTION; GENE EXPRESSION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENETIC CODE; GENETIC TRANSCRIPTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PSEUDOGENE; RNA TRANSLATION; TUMOR CELL; TUMOR GROWTH; AMINO ACID SEQUENCE; ANIMAL; BREAST TUMOR; CELL DIVISION; CELL FREE SYSTEM; CELL STRAIN 3T3; CELL SURVIVAL; CHEMICAL MODEL; CHEMISTRY; CLONOGENIC ASSAY; FLUORESCENCE MICROSCOPY; GENETIC VARIABILITY; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MUTATION; PATHOLOGY; PROMOTER REGION; SEQUENCE HOMOLOGY; TUMOR CELL LINE;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

AMINO ACID SEQUENCE; ANIMALS; BREAST NEOPLASMS; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; CELL-FREE SYSTEM; CLONING, MOLECULAR; COLONY-FORMING UNITS ASSAY; CONNEXIN 43; GENE EXPRESSION; HUMANS; MICE; MICROSCOPY, FLUORESCENCE; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTATION; NIH 3T3 CELLS; PROMOTER REGIONS (GENETICS); PSEUDOGENES; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION, GENETIC; VARIATION (GENETICS);

EID: 2942702193     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207506     Document Type: Article

References (43)

1. Altschul SF, Gish W, Miller W, Myers EW and Lipman DJ. (1990). J. Mol. Biol., 215, 403-410.
2. Andrea JE and Walsh MP. (1995). Biochem. J., 310 (Part 3), 835-843.
3. Bergoffen J, Scherer SS, Wang S, Oronzi Scott M, Bone LJ, Paul DL, Chen K, Lensch M W, Chance PF and Fishbeck KH. (1993). Science, 262, 2039-2042.
4. Boschan C, Borchert A, Ufer C, Thiele BJ and Kuhn H. (2002). Genomics, 79, 387-394.
5. Britz-Cunningham SH, Shah MM, Zuppan CW and Fletcher WH. (1995). N. Engl. J. Med., 332, 1323-1329.
6. Cai J, Jiang WG and Mansel RE. (1998). Int. J. Mol. Med., 1, 273-278.
7. Carystinos GD, Bier A and Batist G. (2001). J. Mamm. Gland Biol. Neoplasia, 6, 431-440.
8. Carystinos GD, Kandouz M, Alaoui-Jamali MA and Batist G. (2003). Mol. Pharmacol., 63, 821-831.
9. Chakrabarti R, McCracken JB, Chakrabarti D and Souba WW. (1995). Gene, 153, 163-199.
10. Elfgang C, Eckert R, Lichtenberg-Frate H, Butterweck A, Traub O, Klein RA, Hulser DF and Willecke K. (1995). J. Cell Biol., 129, 805-817.
11. El-Fouly MH, Trosko JE and Chang CC. (1987). Exp. Cell Res., 168, 422-430.
12. Fishman GI, Eddy RL, Shows TB, Rosenthal L and Leinwand LA. (1991). Genomics, 10, 250-256.
13. Flagg-Newton J and Loewenstein WR. (1979). J. Membr. Biol., 50, 65-100.
14. Foote CI, Zhou L, Zhu X and Nicholson BJ. (1998). J. Cell Biol., 140, 1187-1197.
15. Harrison P, Kumar A, Lan N, Echols N, Snyder M and Gerstein M. (2002). J. Mol. Biol., 316, 409-419.
16. Harrison PM and Gerstein M. (2002). J. Mol. Biol., 318, 1155-1174.
17. Hirotsune S, Yoshida N, Chen A, Garrett L, Sugiyama F, Takahashi S, Yagami K, Wynshaw-Boris A and Yoshiki A. (2003). Nature, 423, 91-96.
18. Hirschi KK, Xu CE, Tsukamoto T and Sager R. (1996). Cell Growth Differ., 7, 861-870.
19. Jordan K, Solan JL, Dominguez M, Sia M, Hand A, Lampe PD and Laird DW. (1999). Mol. Biol. Cell, 10, 2033-2050.
20. Kelsell DP, Dunlop J, Stevens HP, Lench NJ, Laing JN, Parry G, Mueller RF and Leigh IM. (1997). Nature, 387, 80-83.
21. Kleene KC and Mastrangelo MA. (1999). Genomics, 61, 194-200.
22. Korneev SA, Park JH and O'Shea M. (1999). J. Neurosci., 19, 7711-7720.
23. Laird DW, Fistouris P, Batist G, Alpert L, Huynh HT, Carystinos GD and Alaoui-Jamali MA. (1999). Cancer Res., 59, 4104-4110.
24. Laird DW, Jordan K and Shao Q. (2001). Methods Mol. Biol., 154, 135-142.
25. McCarrey JR. (1990). Nucleic Acids Res., 18, 949-955.
26. Mighell AJ, Smith NR, Robinson PA and Markham AF. (2000). FEBS Lett., 468, 109-114.
27. Moorby C and Patel M. (2001). Exp. Cell Res., 271, 238-248.
28. Moran JV, DeBerardinis RJ and Kazazian Jr HH. (1999). Science, 283, 1530-1534.
29. Paznekas WA, Boyadjiev SA, Shapiro RE, Daniels O, Wollnik B, Keegan CE, Innis JW, Dinulos MB, Christian C, Hannibal MC and Jabs EW. (2003). Am. J. Hum. Genet., 72, 408-418.
30. Puget N, Gad S, Perrin-Vidoz L, Sinilnikova OM, Stoppa-Lyonnet D, Lenoir GM and Mazoyer S. (2002). Am. J. Hum. Genet., 70, 858-865.
31. Renaudie F, Yachou AK, Grandchamp B, Jones R and Beaumont C. (1992). Mamm. Genome, 2, 143-149.
32. Sorge J, Gross E, West C and Beutler E. (1990). J. Clin. Invest., 86, 1137-1141.
33. Sun R, Elsea SH, Patel PI and Funk CD. (1998). Cytogenet. Cell Genet., 81, 79-82.
34. Tanooka H, Ootsuyama A and Sasaki H. (1998). Cancer Res., 58, 5649-5651.
35. Thiele H, Berger M, Skalweit A and Thiele BJ. (2000). Eur. J. Biochem., 267, 5473-5481.
36. Torrents D, Suyama M, Zdobnov E and Bork P. (2003). Genome Res., 13, 2559-2567.
37. Uechi T, Maeda N, Tanaka T and Kenmochi N. (2002). Nucleic Acids Res., 30, 5369-5375.
38. Venance L, Piomelli D, Glowinski J and Giaume C. (1995). Nature, 376, 590-594.
39. Vine AL and Bertram JS. (2002). Cancer Metastasis Rev., 21, 199-216.
40. Willecke K, Jungbluth S, Dahl E, Hennemann H, Heynkes R and Grzeschik KH. (1990). Eur. J. Cell Biol., 53, 275-280.
41. Yamasaki H and Naus CC. (1996). Carcinogenesis, 17, 1199-1213.
42. Zhang CL, Tada M, Kobayashi H, Nozaki M, Moriuchi T and Abe H. (2000). Oncogene, 19, 4346-4353.
43. Zhang Z, Harrison PM, Liu Y and Gerstein M. (2003). Genome Res., 13, 2541-2558.