메뉴 건너뛰기




Volumn 449, Issue 2, 2013, Pages 401-413

The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice

Author keywords

Connexin 43; Development; Gap junctional intercellular communication; Mammary gland; Milk ejection; Oculodentodigital dysplasia

Indexed keywords

CONNEXIN 43;

EID: 84871417958     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121070     Document Type: Article
Times cited : (40)

References (43)
  • 2
    • 33645002735 scopus 로고    scopus 로고
    • Life cycle of connexins in health and disease
    • Laird, D. W. (2006) Life cycle of connexins in health and disease. Biochem. J. 394, 527-543
    • (2006) Biochem. J. , vol.394 , pp. 527-543
    • Laird, D.W.1
  • 5
    • 1842789885 scopus 로고    scopus 로고
    • Sex steroids and growth factors in the regulation of mammary gland proliferation, differentiation, and involution
    • DOI 10.1016/j.steroids.2003.12.008, PII S0039128X04000091
    • Lamote, I., Meyer, E., Massart-Leen, A. M. and Burvenich, C. (2004) Sex steroids and growth factors in the regulation of mammary gland proliferation, differentiation, and involution. Steroids 69, 145-159 (Pubitemid 38479388)
    • (2004) Steroids , vol.69 , Issue.3 , pp. 145-159
    • Lamote, I.1    Meyer, E.2    Massart-Leen, A.M.3    Burvenich, C.4
  • 6
    • 33845293447 scopus 로고    scopus 로고
    • Pubertal mammary gland development: Insights from mouse models
    • DOI 10.1007/s10911-006-9024-2
    • Howlin, J., McBryan, J. and Martin, F. (2006) Pubertal mammary gland development: insights from mouse models. J. Mammary Gland Biol. Neoplasia 11, 283-297 (Pubitemid 44869922)
    • (2006) Journal of Mammary Gland Biology and Neoplasia , vol.11 , Issue.3-4 , pp. 283-297
    • Howlin, J.1    McBryan, J.2    Martin, F.3
  • 7
    • 36249001676 scopus 로고    scopus 로고
    • Connexins and gap junctions in mammary gland development and breast cancer progression
    • DOI 10.1007/s00232-007-9052-x
    • McLachlan, E., Shao, Q. and Laird, D. W. (2007) Connexins and gap junctions in mammary gland development and breast cancer progression. J. Membr. Biol. 218, 107-121 (Pubitemid 350132123)
    • (2007) Journal of Membrane Biology , vol.218 , Issue.1-3 , pp. 107-121
    • McLachlan, E.1    Shao, Q.2    Laird, D.W.3
  • 9
    • 0027318152 scopus 로고
    • Specificity of gap junction communication among human mammary cells and connexin transfectants in culture
    • Tomasetto, C., Neveu, M. J., Daley, J., Horan, P. K. and Sager, R. (1993) Specificity of gap junction communication among human mammary cells and connexin transfectants in culture. J. Cell Biol. 122, 157-167 (Pubitemid 23188807)
    • (1993) Journal of Cell Biology , vol.122 , Issue.1 , pp. 157-167
    • Tomasetto, C.1    Neveu, M.J.2    Daley, J.3    Horan, P.K.4    Sager, R.5
  • 10
    • 3242729342 scopus 로고    scopus 로고
    • Altered permeability and modulatory character of connexin channels during mammary gland development
    • DOI 10.1016/j.yexcr.2004.05.003, PII S0014482704002824
    • Locke, D., Stein, T., Davies, C., Morris, J., Harris, A. L., Evans, W. H., Monaghan, P. and Gusterson, B. (2004) Altered permeability and modulatory character of connexin channels during mammary gland development. Exp. Cell Res. 298, 643-660 (Pubitemid 38950879)
    • (2004) Experimental Cell Research , vol.298 , Issue.2 , pp. 643-660
    • Locke, D.1    Stein, T.2    Davies, C.3    Morris, J.4    Harris, A.L.5    Evans, W.H.6    Monaghan, P.7    Gusterson, B.8
  • 12
    • 4344565895 scopus 로고    scopus 로고
    • Developmental regulation of gap junctions and their role in mammary epithelial cell differentiation
    • DOI 10.1023/B:JOMG.0000017432.04930.76, Cell Adhesion in Mammary Gland Biology and Neoplasia
    • El-Sabban, M. E., Abi-Mosleh, L. F. and Talhouk, R. S. (2003) Developmental regulation of gap junctions and their role in mammary epithelial cell differentiation. J. Mammary Gland Biol. Neoplasia 8, 463-473 (Pubitemid 39137507)
    • (2003) Journal of Mammary Gland Biology and Neoplasia , vol.8 , Issue.4 , pp. 463-473
    • El-Sabban, M.E.1    Abi-Mosleh, L.F.2    Talhouk, R.S.3
  • 13
    • 19944427043 scopus 로고    scopus 로고
    • Developmental expression patterns and regulation of connexins in the mouse mammary gland: Expression of connexin30 in lactogenesis
    • DOI 10.1007/s00441-004-0915-5
    • Talhouk, R. S., Elble, R. C., Bassam, R., Daher, M., Sfeir, A., Mosleh, L. A., El-Khoury, H., Hamoui, S., Pauli, B. U. and El-Sabban, M. E. (2005) Developmental expression patterns and regulation of connexins in the mouse mammary gland: Expression of connexin30 in lactogenesis. Cell Tissue Res. 319, 49-59 (Pubitemid 40104638)
    • (2005) Cell and Tissue Research , vol.319 , Issue.1 , pp. 49-59
    • Talhouk, R.S.1    Elble, R.C.2    Bassam, R.3    Daher, M.4    Sfeir, A.5    Mosleh, L.A.6    El-Khoury, H.7    Hamoui, S.8    Pauli, B.U.9    El-Sabban, M.E.10
  • 14
    • 0031059839 scopus 로고    scopus 로고
    • Changes in the phosphorylation states of connexin43 in myoepithelial cells of lactating rat mammary glands
    • Yamanaka, I., Kuraoka, A., Inai, T., Ishibashi, T. and Shibata, Y. (1997) Changes in the phosphorylation states of connexin43 in myoepithelial cells of lactating rat mammary glands. Eur. J. Cell Biol. 72, 166-173 (Pubitemid 27096000)
    • (1997) European Journal of Cell Biology , vol.72 , Issue.2 , pp. 166-173
    • Yamanaka, I.1    Kuraoka, A.2    Inai, T.3    Ishibashi, T.4    Shibata, Y.5
  • 15
    • 0036153330 scopus 로고    scopus 로고
    • Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition
    • Gudjonsson, T., Ronnov-Jessen, L., Villadsen, R., Rank, F., Bissell, M. J. and Petersen, O. W. (2002) Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. J. Cell Sci. 115, 39-50 (Pubitemid 34105527)
    • (2002) Journal of Cell Science , vol.115 , Issue.1 , pp. 39-50
    • Gudjonsson, T.1    Ronnov-Jessen, L.2    Villadsen, R.3    Rank, F.4    Bissell, M.J.5    Petersen, O.W.6
  • 16
    • 25844496162 scopus 로고    scopus 로고
    • Myoepithelial cells: Good fences make good neighbors
    • DOI 10.1186/bcr1286, 190
    • Adriance, M. C., Inman, J. L., Petersen, O. W. and Bissell, M. J. (2005) Myoepithelial cells: good fences make good neighbors. Breast Cancer Res. 7, 190-197 (Pubitemid 41387430)
    • (2005) Breast Cancer Research , vol.7 , Issue.5 , pp. 190-197
    • Adriance, M.C.1    Inman, J.L.2    Petersen, O.W.3    Bissell, M.J.4
  • 20
    • 44349184836 scopus 로고    scopus 로고
    • Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia
    • Plante, I. and Laird, D. W. (2008) Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia. Dev. Biol. 318, 312-322
    • (2008) Dev. Biol. , vol.318 , pp. 312-322
    • Plante, I.1    Laird, D.W.2
  • 21
    • 77953818935 scopus 로고    scopus 로고
    • Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged
    • Plante, I., Wallis, A., Shao, Q. and Laird, D. W. (2010) Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged. Biol. Reprod. 82, 837-847
    • (2010) Biol. Reprod. , vol.82 , pp. 837-847
    • Plante, I.1    Wallis, A.2    Shao, Q.3    Laird, D.W.4
  • 23
    • 3042777256 scopus 로고    scopus 로고
    • Loss of electrical communication, but not plaque formation, after mutations in the cytoplasmic loop of connexin43
    • DOI 10.1016/j.hrthm.2004.03.066, PII S1547527104000967
    • Seki, A., Coombs, W., Taffet, S. M. and Delmar, M. (2004) Loss of electrical communication, but not plaque formation, after mutations in the cytoplasmic loop of connexin43. Heart Rhythm. 1, 227-233 (Pubitemid 38878243)
    • (2004) Heart Rhythm , vol.1 , Issue.2 , pp. 227-233
    • Seki, A.1    Coombs, W.2    Taffet, S.M.3    Delmar, M.4
  • 24
    • 84857033434 scopus 로고    scopus 로고
    • A dominant connexin43 mutant does not have dominant effects on gap junction coupling in astrocytes
    • Wasseff, S., Abrams, C. K. and Scherer, S. S. (2010) A dominant connexin43 mutant does not have dominant effects on gap junction coupling in astrocytes. Neuron Glia Biol. 6, 213-223
    • (2010) Neuron Glia Biol. , vol.6 , pp. 213-223
    • Wasseff, S.1    Abrams, C.K.2    Scherer, S.S.3
  • 26
    • 34547131839 scopus 로고    scopus 로고
    • Differential potency of dominant negative connexin43 mutants in oculodentodigital dysplasia
    • DOI 10.1074/jbc.M609653200
    • Gong, X. Q., Shao, Q., Langlois, S., Bai, D. and Laird, D. W. (2007) Differential potency of dominant negative connexin43 mutants in oculodentodigital dysplasia. J. Biol. Chem. 282, 19190-19202 (Pubitemid 47100175)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.26 , pp. 19190-19202
    • Gong, X.-Q.1    Shao, Q.2    Langlois, S.3    Bai, D.4    Laird, D.W.5
  • 27
    • 44349184836 scopus 로고    scopus 로고
    • Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia
    • Plante, I. and Laird, D. W. (2008) Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia. Dev. Biol. 318, 312-322
    • (2008) Dev. Biol. , vol.318 , pp. 312-322
    • Plante, I.1    Laird, D.W.2
  • 28
    • 80355131580 scopus 로고    scopus 로고
    • Evaluation of mammary gland development and function in mouse models
    • Plante, I., Stewart, M. K. and Laird, D. W. (2011) Evaluation of mammary gland development and function in mouse models. J. Vis. Exp. 53, 2828
    • (2011) J. Vis. Exp. , vol.53 , pp. 2828
    • Plante, I.1    Stewart, M.K.2    Laird, D.W.3
  • 29
    • 23744507557 scopus 로고    scopus 로고
    • Functional characterization of connexin43 mutations found in patients with oculodentodigital dysplasia
    • Shibayama, J., Paznekas, W., Seki, A., Taffet, S., Jabs, E. W., Delmar, M. and Musa, H. (2005) Functional characterization of connexin43 mutations found in patients with oculodentodigital dysplasia. Circ. Res. 96, e83-e91
    • (2005) Circ. Res. , vol.96
    • Shibayama, J.1    Paznekas, W.2    Seki, A.3    Taffet, S.4    Jabs, E.W.5    Delmar, M.6    Musa, H.7
  • 30
    • 0036253066 scopus 로고    scopus 로고
    • Gap junctions and ovarian folliculogenesis
    • Kidder, G. M. and Mhawi, A. A. (2002) Gap junctions and ovarian folliculogenesis. Reproduction 123, 613-620 (Pubitemid 34498335)
    • (2002) Reproduction , vol.123 , Issue.5 , pp. 613-620
    • Kidder, G.M.1    Mhawi, A.A.2
  • 31
    • 64249170988 scopus 로고    scopus 로고
    • Connexin43 phosphorylation: Structural changes and biological effects
    • Solan, J. L. and Lampe, P. D. (2009) Connexin43 phosphorylation: structural changes and biological effects. Biochem. J. 419, 261-272
    • (2009) Biochem. J. , vol.419 , pp. 261-272
    • Solan, J.L.1    Lampe, P.D.2
  • 32
    • 0027532158 scopus 로고
    • The influence of tissue microenvironment (Stroma and extracellular matrix) on the development and function of mammary epithelium
    • Howlett, A. R. and Bissell, M. J. (1993) The influence of tissue microenvironment (stroma and extracellular matrix) on the development and function of mammary epithelium. Epithelial Cell Biol. 2, 79-89 (Pubitemid 23107155)
    • (1993) Epithelial Cell Biology , vol.2 , Issue.2 , pp. 79-89
    • Howlett, A.R.1    Bissell, M.J.2
  • 33
    • 0026661308 scopus 로고
    • Regulation of mammary morphogenesis: Evidence for extracellular matrix-mediated inhibition of ductal budding by transforming growth factor-β1
    • Silberstein, G. B., Flanders, K. C., Roberts, A. B. and Daniel, C. W. (1992) Regulation of mammary morphogenesis: evidence for extracellular matrix-mediated inhibition of ductal budding by transforming growth factor-β1. Dev. Biol. 152, 354-362
    • (1992) Dev. Biol. , vol.152 , pp. 354-362
    • Silberstein, G.B.1    Flanders, K.C.2    Roberts, A.B.3    Daniel, C.W.4
  • 34
    • 0031240327 scopus 로고    scopus 로고
    • Mammary gland development and tumorigenesis in estrogen receptor knockout mice
    • Bocchinfuso, W. P. and Korach, K. S. (1997) Mammary gland development and tumorigenesis in estrogen receptor knockout mice. J. Mammary Gland Biol. Neoplasia 2, 323-334
    • (1997) J. Mammary Gland Biol. Neoplasia , vol.2 , pp. 323-334
    • Bocchinfuso, W.P.1    Korach, K.S.2
  • 35
    • 81055126930 scopus 로고    scopus 로고
    • Misexpression of wingless-related MMTV integration site 5A in mouse mammary gland inhibits the milk ejection response and regulates connexin43 phosphorylation
    • Baxley, S. E., Jiang, W. and Serra, R. (2011) Misexpression of wingless-related MMTV integration site 5A in mouse mammary gland inhibits the milk ejection response and regulates connexin43 phosphorylation. Biol. Reprod. 85, 907-915
    • (2011) Biol. Reprod. , vol.85 , pp. 907-915
    • Baxley, S.E.1    Jiang, W.2    Serra, R.3
  • 36
    • 0029015909 scopus 로고
    • Connexin43 reverses the phenotype of transformed cells and alters their expression of cyclin/cyclin-dependent kinases
    • Chen, S. C., Pelletier, D. B., Ao, P. and Boynton, A. L. (1995) Connexin43 reverses the phenotype of transformed cells and alters their expression of cyclin/cyclin-dependent kinases. Cell Growth Differ. 6, 681-690
    • (1995) Cell Growth Differ. , vol.6 , pp. 681-690
    • Chen, S.C.1    Pelletier, D.B.2    Ao, P.3    Boynton, A.L.4
  • 37
    • 0028889751 scopus 로고
    • Mice lacking cyclin D1 are small and show defects in eye and mammary gland development
    • Fantl, V., Stamp, G., Andrews, A., Rosewell, I. and Dickson, C. (1995) Mice lacking cyclin D1 are small and show defects in eye and mammary gland development. Genes Dev. 9, 2364-2372
    • (1995) Genes Dev. , vol.9 , pp. 2364-2372
    • Fantl, V.1    Stamp, G.2    Andrews, A.3    Rosewell, I.4    Dickson, C.5
  • 38
    • 83755221075 scopus 로고    scopus 로고
    • Macrophages are crucial for epithelial cell death and adipocyte repopulation during mammary gland involution
    • O'Brien, J., Martinson, H., Durand-Rougely, C. and Schedin, P. (2012) Macrophages are crucial for epithelial cell death and adipocyte repopulation during mammary gland involution. Development 139, 269-275
    • (2012) Development , vol.139 , pp. 269-275
    • O'Brien, J.1    Martinson, H.2    Durand-Rougely, C.3    Schedin, P.4
  • 39
    • 34247368931 scopus 로고    scopus 로고
    • Gap-junctional communication is required for mitotic clonal expansion during adipogenesis
    • Yanagiya, T., Tanabe, A. and Hotta, K. (2007) Gap-junctional communication is required for mitotic clonal expansion during adipogenesis. Obesity 15, 572-582 (Pubitemid 46643309)
    • (2007) Obesity , vol.15 , Issue.3 , pp. 572-582
    • Yanagiya, T.1    Tanabe, A.2    Hotta, K.3
  • 41
    • 0035145529 scopus 로고    scopus 로고
    • Dynamics of connexin 43 levels and distribution in the mink (Mustela vison) anterior pituitary are associated with seasonal changes in anterior pituitary prolactin content
    • Vitale, M. L., Cardin, J., Gilula, N. B., Carbajal, M. E. and Pelletier, R. M. (2001) Dynamics of connexin 43 levels and distribution in the mink (Mustela vison) anterior pituitary are associated with seasonal changes in anterior pituitary prolactin content. Biol. Reprod. 64, 625-633 (Pubitemid 32109752)
    • (2001) Biology of Reproduction , vol.64 , Issue.2 , pp. 625-633
    • Vitale, M.L.1    Cardin, J.2    Gilula, N.B.3    Carbajal, M.E.4    Pelletier, R.-M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.