메뉴 건너뛰기




Volumn 167, Issue 3, 2004, Pages 555-562

Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 43; PHOSPHOSERINE; PROTEIN KINASE C; SERINE;

EID: 8444252937     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200404142     Document Type: Article
Times cited : (101)

References (47)
  • 1
    • 0026527868 scopus 로고
    • Connexin43 in MDCK cells: Regulation by a tumor-promoting phorbol ester and calcium
    • Berthoud, V.M., M.L.S. Ledbetter, E.L. Hertzberg, and J.C. Saez. 1992. Connexin43 in MDCK cells: Regulation by a tumor-promoting phorbol ester and calcium. Eur. J. Cell Biol. 57:40-50.
    • (1992) Eur. J. Cell Biol. , vol.57 , pp. 40-50
    • Berthoud, V.M.1    Ledbetter, M.L.S.2    Hertzberg, E.L.3    Saez, J.C.4
  • 2
    • 0027722257 scopus 로고
    • On the mechanism of cell uncoupling induced by a tumor promoter phorbol ester inclone 9 cells, a rat liver epithelial cell line
    • Berthoud, V.M., M. Rook, E.L. Hertzberg, and J.C. Saez. 1993. On the mechanism of cell uncoupling induced by a tumor promoter phorbol ester inclone 9 cells, a rat liver epithelial cell line. Eur. J. Cell Biol. 62:384-396.
    • (1993) Eur. J. Cell Biol. , vol.62 , pp. 384-396
    • Berthoud, V.M.1    Rook, M.2    Hertzberg, E.L.3    Saez, J.C.4
  • 3
    • 0020513440 scopus 로고
    • Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture
    • Boyce, S.T., and R.G. Ham. 1983. Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture. J. Invest. Dermatol. 81:335-405.
    • (1983) J. Invest. Dermatol. , vol.81 , pp. 335-405
    • Boyce, S.T.1    Ham, R.G.2
  • 4
    • 0026045904 scopus 로고
    • The tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the ras oncogene modulate expression and phosphorylation of gap junction proteins
    • Brissette, J.L., N.M. Kumar, N.B. Gilula, and G.P. Dotto. 1991. The tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the ras oncogene modulate expression and phosphorylation of gap junction proteins. Mol. Cell. Biol. 11:5364-5371.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5364-5371
    • Brissette, J.L.1    Kumar, N.M.2    Gilula, N.B.3    Dotto, G.P.4
  • 5
    • 2442446451 scopus 로고    scopus 로고
    • Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia
    • Brown, T.A., T.M. Yang, T. Zaitsevskaia, Y. Xia, C.A. Dunn, R.O. Sigle, B. Knudsen, and W.G. Carter. 2004. Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia. J. Biol. Chem. 279:14772-14783.
    • (2004) J. Biol. Chem. , vol.279 , pp. 14772-14783
    • Brown, T.A.1    Yang, T.M.2    Zaitsevskaia, T.3    Xia, Y.4    Dunn, C.A.5    Sigle, R.O.6    Knudsen, B.7    Carter, W.G.8
  • 6
    • 0022359409 scopus 로고
    • Cutaneous tissue repair: Basic biological considerations
    • Clark, R.A. 1985. Cutaneous tissue repair: basic biological considerations. J. Am. Acad. Dermatol. 13:701-725.
    • (1985) J. Am. Acad. Dermatol. , vol.13 , pp. 701-725
    • Clark, R.A.1
  • 7
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark, E.A., and J.S. Brugge. 1995. Integrins and signal transduction pathways: the road taken. Science. 268:233-239.
    • (1995) Science , vol.268 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 8
    • 0037160066 scopus 로고    scopus 로고
    • Casein kinase I regulates connexin43 gap junction assembly
    • Cooper, C.D., and P.D. Lampe. 2002, Casein kinase I regulates connexin43 gap junction assembly. J. Biol. Chem. 277:44962-44968.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44962-44968
    • Cooper, C.D.1    Lampe, P.D.2
  • 9
    • 0025261843 scopus 로고
    • Phosphorylation of connexin43 gap junction protein in uninfected and Rous sarcoma virus-transformed mammalian fibroblasts
    • Crow, D.S., E.C. Beyer, D.L. Paul, S.S. Kobe, and A.F. Lau. 1990. Phosphorylation of connexin43 gap junction protein in uninfected and Rous sarcoma virus-transformed mammalian fibroblasts. Mol. Cell. Biol. 10: 1754-1763.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1754-1763
    • Crow, D.S.1    Beyer, E.C.2    Paul, D.L.3    Kobe, S.S.4    Lau, A.F.5
  • 10
    • 0034773461 scopus 로고    scopus 로고
    • Multiple epidermal connexins are expressed in different keratinocyte subpopulations including connexin 31
    • Di, W.L., E.L. Rugg, I.M. Leigh, and D.P. Kelsell. 2001. Multiple epidermal connexins are expressed in different keratinocyte subpopulations including connexin 31. J. Invest. Dermatol. 117:958-964.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 958-964
    • Di, W.L.1    Rugg, E.L.2    Leigh, I.M.3    Kelsell, D.P.4
  • 11
    • 0028016024 scopus 로고
    • Expression and function of connexin in normal and transformed human keratinocytes in culture
    • Fitzgerald, D.J., N.E. Fusenig, P. Boukamp, C. Piccoli, M. Mesnil, and H. Yamasaki. 1994. Expression and function of connexin in normal and transformed human keratinocytes in culture. Carcinogenesis. 15:1859-1865.
    • (1994) Carcinogenesis , vol.15 , pp. 1859-1865
    • Fitzgerald, D.J.1    Fusenig, N.E.2    Boukamp, P.3    Piccoli, C.4    Mesnil, M.5    Yamasaki, H.6
  • 12
    • 0027990415 scopus 로고
    • Wound repair in the context of extracellular matrix
    • Gailit, J., and R.A. Clark. 1994. Wound repair in the context of extracellular matrix. Curr. Opin. Cell Biol. 6:717-725.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 717-725
    • Gailit, J.1    Clark, R.A.2
  • 13
    • 0037184068 scopus 로고    scopus 로고
    • Heterotypic and homotypic gap junction channels mediate the selective transfer of endogenous molecules between cells
    • Goldberg, G.S., A.P. Moreno, and P.D. Lampe. 2002. Heterotypic and homotypic gap junction channels mediate the selective transfer of endogenous molecules between cells. J. Biol. Chem. 277:36725-36730.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36725-36730
    • Goldberg, G.S.1    Moreno, A.P.2    Lampe, P.D.3
  • 14
    • 0028361088 scopus 로고
    • Expression of gap junction proteins Cx26, Cx31.1, Cx37, and Cx43 in developing and mature rat epidermis
    • Goliger, J.A., and D.L. Paul. 1994. Expression of gap junction proteins Cx26, Cx31.1, Cx37, and Cx43 in developing and mature rat epidermis. Dev. Dyn. 200:1-13.
    • (1994) Dev. Dyn. , vol.200 , pp. 1-13
    • Goliger, J.A.1    Paul, D.L.2
  • 15
    • 0028838703 scopus 로고
    • Wounding alters epidermal connexin expression and gap junction-mediated intercellular communication
    • Goliger, J.A., and D.L. Paul. 1995. Wounding alters epidermal connexin expression and gap junction-mediated intercellular communication. Mol. Biol. Cell. 6:1491-1501.
    • (1995) Mol. Biol. Cell. , vol.6 , pp. 1491-1501
    • Goliger, J.A.1    Paul, D.L.2
  • 16
    • 0026601915 scopus 로고
    • Wound repair, keratinocyte activation and integrin modulation
    • Grinnell, F. 1992. Wound repair, keratinocyte activation and integrin modulation. J. Cell Sci. 101:1-5.
    • (1992) J. Cell Sci. , vol.101 , pp. 1-5
    • Grinnell, F.1
  • 17
    • 0025959178 scopus 로고
    • Tissue-specific distribution of differentially phosphorylated forms of Cx43
    • Kadle, R., J.T. Zhang, and B.J. Nicholson. 1991. Tissue-specific distribution of differentially phosphorylated forms of Cx43. Mol. Cell. Biol. 11:363-369.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 363-369
    • Kadle, R.1    Zhang, J.T.2    Nicholson, B.J.3
  • 19
    • 0035168133 scopus 로고    scopus 로고
    • Inhibition of endothelial wound repair by dominant negative connexin inhibitors
    • Kwak, B.R., M.S. Pepper, D.B. Gros, and P. Meda. 2001. Inhibition of endothelial wound repair by dominant negative connexin inhibitors. Mol. Biol. Cell. 12:831-845.
    • (2001) Mol. Biol. Cell. , vol.12 , pp. 831-845
    • Kwak, B.R.1    Pepper, M.S.2    Gros, D.B.3    Meda, P.4
  • 20
    • 0026025267 scopus 로고
    • Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes
    • Laird, D.W., K.L. Puranam, and J.P. Revel. 1991. Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes. Biochem. J. 273:67-72.
    • (1991) Biochem. J. , vol.273 , pp. 67-72
    • Laird, D.W.1    Puranam, K.L.2    Revel, J.P.3
  • 21
    • 0028584195 scopus 로고
    • Analyzing phorbol ester effects on gap junction communication: A dramatic inhibition of assembly
    • Lampe, P.D. 1994. Analyzing phorbol ester effects on gap junction communication: a dramatic inhibition of assembly. J. Cell Biol. 127:1895-1905.
    • (1994) J. Cell Biol. , vol.127 , pp. 1895-1905
    • Lampe, P.D.1
  • 22
    • 0032517773 scopus 로고    scopus 로고
    • Cellular interaction of integrin α3β1 with laminin 5 promotes gap junctional communication
    • Lampe, P.D., B.P. Nguyen, S. Gil, M. Usui, J. Olerud, Y. Takada, and W.G. Carter. 1998. Cellular interaction of integrin α3β1 with laminin 5 promotes gap junctional communication. J. Cell Biol. 143:1735-1747.
    • (1998) J. Cell Biol. , vol.143 , pp. 1735-1747
    • Lampe, P.D.1    Nguyen, B.P.2    Gil, S.3    Usui, M.4    Olerud, J.5    Takada, Y.6    Carter, W.G.7
  • 23
    • 0034717680 scopus 로고    scopus 로고
    • Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication
    • Lampe, P.D., E.M. TenBroek, J.M. Burt, W.E. Kurata, R.G. Johnson, and A.F. Lau. 2000. Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication. J. Cell Biol. 126:1503-1512.
    • (2000) J. Cell Biol. , vol.126 , pp. 1503-1512
    • Lampe, P.D.1    TenBroek, E.M.2    Burt, J.M.3    Kurata, W.E.4    Johnson, R.G.5    Lau, A.F.6
  • 24
    • 0036417884 scopus 로고    scopus 로고
    • Calcium: A potential central regulator in wound healing in the skin
    • Lansdown, A.B. 2002. Calcium: a potential central regulator in wound healing in the skin. Wound Repair Regen. 10:271-285.
    • (2002) Wound Repair Regen. , vol.10 , pp. 271-285
    • Lansdown, A.B.1
  • 25
    • 0030934532 scopus 로고    scopus 로고
    • Wound healing-aiming for perfect skin regeneration
    • Martin, P. 1997. Wound healing-aiming for perfect skin regeneration. Science. 276:75-81.
    • (1997) Science , vol.276 , pp. 75-81
    • Martin, P.1
  • 26
    • 0025155347 scopus 로고
    • Differential phosphorylation of gap junction protein connexin43 in junctional communication-competent and -deficient cell lines
    • Musil, L.S., B.A. Cunningham, G.M. Edelman, and D.A. Goodenough. 1990. Differential phosphorylation of gap junction protein connexin43 in junctional communication-competent and -deficient cell lines. J. Cell Biol. 111:2077-2088.
    • (1990) J. Cell Biol. , vol.111 , pp. 2077-2088
    • Musil, L.S.1    Cunningham, B.A.2    Edelman, G.M.3    Goodenough, D.A.4
  • 27
    • 0041844989 scopus 로고    scopus 로고
    • Co-expression of p16(INK4A) and laminin 5 gamma2 by microinvasive and superficial squamous cell carcinomas in vivo and by migrating wound and senescent keratinocytes in culture
    • Natarajan, E., M. Saeb, C.P. Crum, S.B. Woo, P.H. McKee, and J.G. Rheinwald. 2003. Co-expression of p16(INK4A) and laminin 5 gamma2 by microinvasive and superficial squamous cell carcinomas in vivo and by migrating wound and senescent keratinocytes in culture. Am. J. Pathol. 163:477-491.
    • (2003) Am. J. Pathol. , vol.163 , pp. 477-491
    • Natarajan, E.1    Saeb, M.2    Crum, C.P.3    Woo, S.B.4    McKee, P.H.5    Rheinwald, J.G.6
  • 28
    • 0034791675 scopus 로고    scopus 로고
    • p63 expression during normal cutaneous wound healing in humans
    • Noszczyk, B.H., and S.T. Majewski. 2001. p63 expression during normal cutaneous wound healing in humans. Plast. Reconstr. Surg. 108:1242-1247.
    • (2001) Plast. Reconstr. Surg. , vol.108 , pp. 1242-1247
    • Noszczyk, B.H.1    Majewski, S.T.2
  • 29
    • 0029098881 scopus 로고
    • A model for the study of wounds in normal elderly adults and patients with peripheral vascular disease or diabetes mellitus
    • Olerud, J.E., G.F. Odland, E.M. Burgess, C.R. Wyss, L.D. Fisher, and F.A. Matsen III. 1995. A model for the study of wounds in normal elderly adults and patients with peripheral vascular disease or diabetes mellitus. J. Surg. Res. 59:349-360.
    • (1995) J. Surg. Res. , vol.59 , pp. 349-360
    • Olerud, J.E.1    Odland, G.F.2    Burgess, E.M.3    Wyss, C.R.4    Fisher, L.D.5    Matsen III, F.A.6
  • 30
    • 0035082755 scopus 로고    scopus 로고
    • Quantitative analysis of the proliferation of epidermal cells using a human skin organ culture system and the effect of DbcAMP using markers of proliferation (BrdU, Ki-67, PCNA)
    • Onuma, H., C. Mastui, and M. Morohashi. 2001. Quantitative analysis of the proliferation of epidermal cells using a human skin organ culture system and the effect of DbcAMP using markers of proliferation (BrdU, Ki-67, PCNA). Arch. Dermatol. Res. 293:133-138.
    • (2001) Arch. Dermatol. Res. , vol.293 , pp. 133-138
    • Onuma, H.1    Mastui, C.2    Morohashi, M.3
  • 32
    • 0026526984 scopus 로고
    • An activator of protein kinase C inhibits gap junction communication between cultured bovine lens cells
    • Reynhout, J.K., P.D. Lampe, and R.G. Johnson. 1992. An activator of protein kinase C inhibits gap junction communication between cultured bovine lens cells. Exp. Cell Res. 198:337-342.
    • (1992) Exp. Cell Res. , vol.198 , pp. 337-342
    • Reynhout, J.K.1    Lampe, P.D.2    Johnson, R.G.3
  • 33
    • 0034068362 scopus 로고    scopus 로고
    • Connexins: A connection with the skin
    • Richard, G. 2000. Connexins: a connection with the skin. Exp. Dermatol. 9:77-96.
    • (2000) Exp. Dermatol. , vol.9 , pp. 77-96
    • Richard, G.1
  • 34
    • 0026481014 scopus 로고
    • Multiple gap junction genes are utilized during rat skin and hair development
    • Risek, B., F.G. Klier, and N.B. Gilula. 1992. Multiple gap junction genes are utilized during rat skin and hair development. Development. 116:639-651.
    • (1992) Development , vol.116 , pp. 639-651
    • Risek, B.1    Klier, F.G.2    Gilula, N.B.3
  • 35
    • 0035234296 scopus 로고    scopus 로고
    • How to close a gap junction channel. Efficacies and potencies of uncoupling agents
    • Rozental, R., M. Srinivas, and D.C. Spray. 2001. How to close a gap junction channel. Efficacies and potencies of uncoupling agents. Methods Mol. Biol. 154:447-476.
    • (2001) Methods Mol. Biol. , vol.154 , pp. 447-476
    • Rozental, R.1    Srinivas, M.2    Spray, D.C.3
  • 36
    • 17344390158 scopus 로고    scopus 로고
    • Plasma membrane channels formed by connexins: Their regulation and functions
    • Saez, J.C., V.M. Berthoud, M.C. Branes, A.D. Martinez, and E.C. Beyer. 2003. Plasma membrane channels formed by connexins: their regulation and functions. Physiol. Rev. 83:1359-1400.
    • (2003) Physiol. Rev. , vol.83 , pp. 1359-1400
    • Saez, J.C.1    Berthoud, V.M.2    Branes, M.C.3    Martinez, A.D.4    Beyer, E.C.5
  • 37
    • 0031409112 scopus 로고    scopus 로고
    • Changes in the expression of gap junction proteins (connexins) in hamster tongue epithelium during would healing and carcinogenesis
    • Saitoh, M., M. Oyamada, Y. Oyamada, T. Kaku, and M. Mori. 1997. Changes in the expression of gap junction proteins (connexins) in hamster tongue epithelium during would healing and carcinogenesis. Carcinogenesis. 18:1319-1328.
    • (1997) Carcinogenesis , vol.18 , pp. 1319-1328
    • Saitoh, M.1    Oyamada, M.2    Oyamada, Y.3    Kaku, T.4    Mori, M.5
  • 39
    • 0037821639 scopus 로고    scopus 로고
    • p38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing: Evidence of cross-talk activation between MAP kinase cascades
    • Sharma, G.D., J. He, and H.E. Bazan. 2003. p38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing: evidence of cross-talk activation between MAP kinase cascades. J. Biol. Chem. 278: 21989-21997.
    • (2003) J. Biol. Chem. , vol.278 , pp. 21989-21997
    • Sharma, G.D.1    He, J.2    Bazan, H.E.3
  • 40
    • 0032567887 scopus 로고    scopus 로고
    • Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block
    • Simon, A.M., D.A. Goodenough, and D.L. Paul. 1998. Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block. Curr. Biol. 8:295-298.
    • (1998) Curr. Biol. , vol.8 , pp. 295-298
    • Simon, A.M.1    Goodenough, D.A.2    Paul, D.L.3
  • 41
    • 0037672632 scopus 로고    scopus 로고
    • Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation
    • Solan, J.L., M.D. Fry, E.M. TenBroek, and P.D. Lampe. 2003. Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation. J. Cell Sci. 116:2203-2211.
    • (2003) J. Cell Sci. , vol.116 , pp. 2203-2211
    • Solan, J.L.1    Fry, M.D.2    TenBroek, E.M.3    Lampe, P.D.4
  • 42
    • 0029739492 scopus 로고    scopus 로고
    • Changes in beta 4 integrin expression and localization in vivo in response to corneal epithelial injury
    • Stepp, M.A., L. Zhu, and R. Cranfill. 1996. Changes in beta 4 integrin expression and localization in vivo in response to corneal epithelial injury. Invest. Ophthatmol. Vis. Sci. 37:1593-1601.
    • (1996) Invest. Ophthatmol. Vis. Sci. , vol.37 , pp. 1593-1601
    • Stepp, M.A.1    Zhu, L.2    Cranfill, R.3
  • 43
    • 0034020357 scopus 로고    scopus 로고
    • The alpha isoform of protein kinase C is involved in signaling the response of desmosomes to wounding in cultured epithelial cells
    • Wallis, S., S. Lloyd, I. Wise, G. Ireland, T.P. Fleming, and D. Garrod. 2000. The alpha isoform of protein kinase C is involved in signaling the response of desmosomes to wounding in cultured epithelial cells. Mol. Biol. Cell. 11:1077-1092.
    • (2000) Mol. Biol. Cell. , vol.11 , pp. 1077-1092
    • Wallis, S.1    Lloyd, S.2    Wise, I.3    Ireland, G.4    Fleming, T.P.5    Garrod, D.6
  • 44
    • 0037059499 scopus 로고    scopus 로고
    • Unique and redundant connexin contributions to lens development
    • White, T.W. 2002. Unique and redundant connexin contributions to lens development. Science. 295:319-320.
    • (2002) Science , vol.295 , pp. 319-320
    • White, T.W.1
  • 47
    • 0034458415 scopus 로고    scopus 로고
    • Scraped-wounding causes activation and association of C-Src tyrosine kinase with microtubules in cultured keratinocytes
    • Yamada, T., Y. Aoyama, M.K. Owada, H. Kawakatsu, and Y. Kitajima. 2000. Scraped-wounding causes activation and association of C-Src tyrosine kinase with microtubules in cultured keratinocytes. Cell Struct. Funct. 25:351-359.
    • (2000) Cell Struct. Funct. , vol.25 , pp. 351-359
    • Yamada, T.1    Aoyama, Y.2    Owada, M.K.3    Kawakatsu, H.4    Kitajima, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.