Evaluation of mammary gland development and function in mouse models

Journal of Visualized Experiments

Volumn , Issue 53, 2011, Pages

  Plante, Isabelle ^a   Stewart, Michael K G ^a   Laird, Dale W ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Developmental Biology; Issue 53; Mammary gland; Mammary gland development; Milk ejection; Mouse model; Whole mount

Indexed keywords

EID: 80355131580     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/2828     Document Type: Article

References (19)

1. Geddes, D.T. Inside the lactating breast: the latest anatomy research. J Midwifery Womens Health. 52 (6), 556 (2007).
2. Sternlicht, M.D. Key stages in mammary gland development: the cues that regulate ductal branching morphogenesis. Breast Cancer Res. 8 (1), 201 (2006).
3. Silberstein, G.B., Flanders, K.C., Roberts, A.B., & Daniel, C.W. Regulation of mammary morphogenesis: evidence for extracellular matrix-mediated inhibition of ductal budding by transforming growth factor-beta 1. Dev Biol. 152 (2), 354 (1992).
4. Daniel, C.W., Robinson, S., & Silberstein, G.B. The role of TGF-beta in patterning and growth of the mammary ductal tree. J Mammary Gland Biol Neoplasia. 1 (4), 331 (1996).
5. Neville, M.C., & Daniel, C.W. The Mammary gland: development, regulation, and function. (Plenum Press, New York, 1987).
6. Oakes, S.R., Hilton, H.N. and Ormandy, C.J. The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium. Breast Cancer Res. 8 (2), 207 (2006).
7. Anderson, S.M., Rudolph, M.C., McManaman, J.L., & Neville, M.C. Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis! Breast Cancer Res. 9 (1), 204 (2007).
8. Reversi, A., Cassoni, P., & Chini, B. Oxytocin receptor signaling in myoepithelial and cancer cells. J Mammary Gland Biol Neoplasia. 10 (3), 221 (2005).
9. Haslam, S.Z. Cell to cell interactions and normal mammary gland function. J Dairy Sci. 71 (10), 2843 (1988).
10. Plante, I., & Laird, D.W. Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia. Dev Biol. 318 (2), 312 (2008).
11. Talhouk, R.S., et al. Heterocellular interaction enhances recruitment of alpha and beta-catenins and ZO-2 into functional gap-junction complexes and induces gap junction-dependant differentiation of mammary epithelial cells. Exp Cell Res. 314 (18), 3275 (2008).
12. Palmer, C.A., Neville, M.C., Anderson, S.M., & McManaman, J.L. Analysis of lactation defects in transgenic mice. J Mammary Gland Biol Neoplasia. 11 (3-4), 269 (2006).
13. Howlin, J., McBryan, J., & Martin, F. Pubertal mammary gland development: insights from mouse models. J Mammary Gland Biol Neoplasia. 11 (3-4), 283 (2006).
14. You, L., et al. Modulation of mammary gland development in prepubertal male rats exposed to genistein and methoxychlor. Toxicol Sci. 66 (2), 216 (2002).
15. Grill, C.J., Cohick, W.S., & Sherman, A.R. Postpubertal development of the rat mammary gland is preserved during iron deficiency. J Nutr. 131 (5), 1444 (2001).
16. Hennighausen, L., & Robinson, G.W. Think globally, act locally: the making of a mouse mammary gland. Genes Dev. 12 (4), 449 (1998).
17. Aupperlee, M.D., et al. Strain-specific differences in the mechanisms of progesterone regulation of murine mammary gland development. Endocrinology. 150 (3), 1485 (2009).
18. Montero Girard, G., et al. Association of estrogen receptor-alpha and progesterone receptor A expression with hormonal mammary carcinogenesis: role of the host microenvironment. Breast Cancer Res. 9 (2), R22 (2007).
19. Moore, D.M., Vogl, A.W., Baimbridge, K., & Emerman, J.T. Effect of calcium on oxytocin-induced contraction of mammary gland myoepithelium as visualized by NBD-phallacidin. J Cell Sci. 88 (5), 563 (1987).