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Volumn 2, Issue 1, 2013, Pages 1-15

Gap junctions and Bystander effects: Good Samaritans and executioners

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CHAPERONE; CONNEXIN 36; CONNEXIN 43; CYCLIC AMP; GAP JUNCTION PROTEIN; INOSITOL TRISPHOSPHATE;

EID: 84879192764     PISSN: 2190460X     EISSN: 21904618     Source Type: Journal    
DOI: 10.1002/wmts.72     Document Type: Review
Times cited : (62)

References (97)
  • 1
    • 0032408307 scopus 로고    scopus 로고
    • The discovery of metabolic co-operation.
    • Pitts JD. The discovery of metabolic co-operation. Bioessays 1998, 20:1047-1051.
    • (1998) Bioessays , vol.20 , pp. 1047-1051
    • Pitts, J.D.1
  • 2
    • 0015090124 scopus 로고
    • Hypox anthine-guanine phosphoribosyltransferase deficiency: chemical agents selective for mutant or normal cultured fibroblasts in mixed and heterozygote cultures.
    • Fujimoto WY, Subak-Sharpe JH, Seegmiller JE. Hypox anthine-guanine phosphoribosyltransferase deficiency: chemical agents selective for mutant or normal cultured fibroblasts in mixed and heterozygote cultures. Proc Natl Acad Sci U S A 1971, 68:1516-1519.
    • (1971) Proc Natl Acad Sci U S A , vol.68 , pp. 1516-1519
    • Fujimoto, W.Y.1    Subak-Sharpe, J.H.2    Seegmiller, J.E.3
  • 3
    • 0019393515 scopus 로고
    • Non-selective junctional communication between some different mammalian cell types in primary culture.
    • Hunter GK, Pitts JD. Non-selective junctional communication between some different mammalian cell types in primary culture. J Cell Sci 1981, 49:163-175.
    • (1981) J Cell Sci , vol.49 , pp. 163-175
    • Hunter, G.K.1    Pitts, J.D.2
  • 4
    • 84862841096 scopus 로고    scopus 로고
    • Tunneling nanotubes: emerging view of their molecular components and formation mechanisms.
    • Kimura S, Hase K, Ohno H. Tunneling nanotubes: emerging view of their molecular components and formation mechanisms. Exper Cell Res 2012, 318:1699-1706.
    • (2012) Exper Cell Res , vol.318 , pp. 1699-1706
    • Kimura, S.1    Hase, K.2    Ohno, H.3
  • 5
    • 79953802454 scopus 로고    scopus 로고
    • Signaling pathways underpinning the manifestations of ionizing radiation-induced bystander effects.
    • Hamada N, Maeda M, Otsuka K, Tomita M. Signaling pathways underpinning the manifestations of ionizing radiation-induced bystander effects. Curr Mol Pharmacol 2011, 4:79-95.
    • (2011) Curr Mol Pharmacol , vol.4 , pp. 79-95
    • Hamada, N.1    Maeda, M.2    Otsuka, K.3    Tomita, M.4
  • 6
    • 16644401532 scopus 로고    scopus 로고
    • Cellular injury induces activation of MAPK via P2Y receptors.
    • Yang L, Cranson D, Trinkaus-Randall V. Cellular injury induces activation of MAPK via P2Y receptors. J Cell Biochem 2004, 91:938-950.
    • (2004) J Cell Biochem , vol.91 , pp. 938-950
    • Yang, L.1    Cranson, D.2    Trinkaus-Randall, V.3
  • 7
    • 69149107146 scopus 로고    scopus 로고
    • DNA-triggered innate immune responses are propagated by gap junction communication.
    • Patel SJ, King KR, Casali M, Yarmush ML. DNA-triggered innate immune responses are propagated by gap junction communication. Proc Natl Acad Sci U S A 2009, 106:12867-12872.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12867-12872
    • Patel, S.J.1    King, K.R.2    Casali, M.3    Yarmush, M.L.4
  • 9
    • 18944394972 scopus 로고    scopus 로고
    • Evolution of gap junction proteins-the pannexin alternative.
    • Panchin YV. Evolution of gap junction proteins-the pannexin alternative. J Exp Biol 2005, 208: 1415-1419.
    • (2005) J Exp Biol , vol.208 , pp. 1415-1419
    • Panchin, Y.V.1
  • 10
    • 80053933421 scopus 로고    scopus 로고
    • Functional interactions between polydnavirus and host cellular innexins.
    • Marziano NK, Hasegawa DK, Phelan P, Turnbull MW. Functional interactions between polydnavirus and host cellular innexins. J Virol 2011, 85:10222-10229.
    • (2011) J Virol , vol.85 , pp. 10222-10229
    • Marziano, N.K.1    Hasegawa, D.K.2    Phelan, P.3    Turnbull, M.W.4
  • 11
    • 33750300467 scopus 로고    scopus 로고
    • Functional connexin 'hemichannels': a critical appraisal.
    • Spray DC, Ye ZC, Ransom BR. Functional connexin 'hemichannels': a critical appraisal. Glia 2006, 54: 758-773.
    • (2006) Glia , vol.54 , pp. 758-773
    • Spray, D.C.1    Ye, Z.C.2    Ransom, B.R.3
  • 12
    • 62549143109 scopus 로고    scopus 로고
    • Connexins, pannexins, innexins: novel roles of 'hemi-channels'.
    • Scemes E, Spray DC, Meda P. Connexins, pannexins, innexins: novel roles of 'hemi-channels'. Pflugers Arch 2009, 457:1207-1226.
    • (2009) Pflugers Arch , vol.457 , pp. 1207-1226
    • Scemes, E.1    Spray, D.C.2    Meda, P.3
  • 16
    • 0033529651 scopus 로고    scopus 로고
    • Propagation of cardiomyocyte hypercontracture by passage of Na(+) through gap junctions.
    • Ruiz-Meana M, Garcia-Dorado D, Hofstaetter B, Piper HM, Soler-Soler J. Propagation of cardiomyocyte hypercontracture by passage of Na(+) through gap junctions. Circ Res 1999, 85:280-287.
    • (1999) Circ Res , vol.85 , pp. 280-287
    • Ruiz-Meana, M.1    Garcia-Dorado, D.2    Hofstaetter, B.3    Piper, H.M.4    Soler-Soler, J.5
  • 17
    • 0015885283 scopus 로고
    • Transfer of cytoplasmic and nuclear proteins between cells in culture.
    • Kolodny GM. Transfer of cytoplasmic and nuclear proteins between cells in culture. J Mol Biol 1973, 78:197-210.
    • (1973) J Mol Biol , vol.78 , pp. 197-210
    • Kolodny, G.M.1
  • 18
    • 0017576177 scopus 로고
    • Permeability of junctions between animal cells. Intercellular transfer of nucleotides but not of macromolecules.
    • Pitts JD, Simms JW. Permeability of junctions between animal cells. Intercellular transfer of nucleotides but not of macromolecules. Exper Cell Res 1977, 104:153-163.
    • (1977) Exper Cell Res , vol.104 , pp. 153-163
    • Pitts, J.D.1    Simms, J.W.2
  • 19
    • 0018647726 scopus 로고
    • Permeability of the cell-to-cell membrane channels in mammalian cell juncton.
    • Flagg-Newton J, Simpson I, Loewenstein WR. Permeability of the cell-to-cell membrane channels in mammalian cell juncton. Science 1979, 205:404-407.
    • (1979) Science , vol.205 , pp. 404-407
    • Flagg-Newton, J.1    Simpson, I.2    Loewenstein, W.R.3
  • 20
    • 33645002735 scopus 로고    scopus 로고
    • Life cycle of connexins in health and disease.
    • Laird DW. Life cycle of connexins in health and disease. Biochem J 2006, 394:527-543.
    • (2006) Biochem J , vol.394 , pp. 527-543
    • Laird, D.W.1
  • 23
    • 0017850829 scopus 로고
    • Transmission of hormonal stimulation by cell-to-cell communication.
    • Lawrence TS, Beers WH, Gilula NB. Transmission of hormonal stimulation by cell-to-cell communication. Nature 1978, 272:501-506.
    • (1978) Nature , vol.272 , pp. 501-506
    • Lawrence, T.S.1    Beers, W.H.2    Gilula, N.B.3
  • 24
    • 0037154271 scopus 로고    scopus 로고
    • Function of the voltage gate of gap junction channels: selective exclusion of molecules.
    • Qu Y, Dahl G. Function of the voltage gate of gap junction channels: selective exclusion of molecules. Proc Natl Acad Sci U S A 2002, 99:697-702.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 697-702
    • Qu, Y.1    Dahl, G.2
  • 25
    • 0343058567 scopus 로고
    • Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.
    • Saez JC, Connor JA, Spray DC, Bennett MV. Hepatocyte gap junctions are permeable to the second messenger, inositol 1, 4, 5-trisphosphate, and to calcium ions. Proc Natl Acad Sci U S A 1989, 86:2708-2712.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 2708-2712
    • Saez, J.C.1    Connor, J.A.2    Spray, D.C.3    Bennett, M.V.4
  • 26
    • 33646158906 scopus 로고    scopus 로고
    • A stochastic two-dimensional model of intercellular Ca2+ wave spread in glia.
    • Iacobas DA, Suadicani SO, Spray DC, Scemes E. A stochastic two-dimensional model of intercellular Ca2+ wave spread in glia. Biophys J 2006, 90:24-41.
    • (2006) Biophys J , vol.90 , pp. 24-41
    • Iacobas, D.A.1    Suadicani, S.O.2    Spray, D.C.3    Scemes, E.4
  • 28
    • 66149173401 scopus 로고    scopus 로고
    • Pannexin 1: the molecular substrate of astrocyte 'hemichannels'.
    • Iglesias R, Dahl G, Qiu F, Spray DC, Scemes E. Pannexin 1: the molecular substrate of astrocyte 'hemichannels'. J Neurosci 2009, 29:7092-7097.
    • (2009) J Neurosci , vol.29 , pp. 7092-7097
    • Iglesias, R.1    Dahl, G.2    Qiu, F.3    Spray, D.C.4    Scemes, E.5
  • 29
    • 67650490234 scopus 로고    scopus 로고
    • Selective astrocytic gap junctional trafficking of molecules involved in the glycolytic pathway: impact on cellular brain imaging.
    • Gandhi GK, Cruz NF, Ball KK, Theus SA, Dienel GA. Selective astrocytic gap junctional trafficking of molecules involved in the glycolytic pathway: impact on cellular brain imaging. J Neurochem 2009, 110: 857-869.
    • (2009) J Neurochem , vol.110 , pp. 857-869
    • Gandhi, G.K.1    Cruz, N.F.2    Ball, K.K.3    Theus, S.A.4    Dienel, G.A.5
  • 30
    • 57349185900 scopus 로고    scopus 로고
    • Astroglial metabolic networks sustain hippocampal synaptic transmission.
    • Rouach N, Koulakoff A, Abudara V, Willecke K, Giaume C. Astroglial metabolic networks sustain hippocampal synaptic transmission. Science 2008, 322:1551-1555.
    • (2008) Science , vol.322 , pp. 1551-1555
    • Rouach, N.1    Koulakoff, A.2    Abudara, V.3    Willecke, K.4    Giaume, C.5
  • 31
    • 70349371373 scopus 로고    scopus 로고
    • Astrocytic 'power-grid': delivery upon neuronal demand.
    • Stout RF, Jr, Spray DC, Parpura V. Astrocytic 'power-grid': delivery upon neuronal demand. Cellscience 2009, 5:34-43.
    • (2009) Cellscience , vol.5 , pp. 34-43
    • Stout, R.F.1    Spray, D.C.2    Parpura, V.3
  • 32
    • 78649700963 scopus 로고    scopus 로고
    • Astrocytes are 'good scouts': being prepared also helps neighboring neurons.
    • Dienel GA. Astrocytes are 'good scouts': being prepared also helps neighboring neurons. J Cereb Blood Flow Metab 2010, 30:1893-1894.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1893-1894
    • Dienel, G.A.1
  • 33
    • 0028071271 scopus 로고
    • The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats.
    • Ram Z, Walbridge S, Shawker T, Culver KW, Blaese RM, Oldfield EH. The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats. J Neurosurg 1994, 81:256-260.
    • (1994) J Neurosurg , vol.81 , pp. 256-260
    • Ram, Z.1    Walbridge, S.2    Shawker, T.3    Culver, K.W.4    Blaese, R.M.5    Oldfield, E.H.6
  • 34
    • 0021055765 scopus 로고
    • Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells.
    • Cheng YC, Grill SP, Dutschman GE, Nakayama K, Bastow KF. Metabolism of 9-(1, 3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells. J Biol Chem 1983, 258:12460-12464.
    • (1983) J Biol Chem , vol.258 , pp. 12460-12464
    • Cheng, Y.C.1    Grill, S.P.2    Dutschman, G.E.3    Nakayama, K.4    Bastow, K.F.5
  • 35
    • 0027787053 scopus 로고
    • In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy.
    • Bi WL, Parysek LM, Warnick R, Stambrook PJ. In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy. Hum Gene Ther 1993, 4:725-731.
    • (1993) Hum Gene Ther , vol.4 , pp. 725-731
    • Bi, W.L.1    Parysek, L.M.2    Warnick, R.3    Stambrook, P.J.4
  • 36
    • 0030757097 scopus 로고    scopus 로고
    • The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions.
    • Vrionis FD, Wu JK, Qi P, Waltzman M, Cherington V, Spray DC. The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions. Gene Ther 1997, 4:577-585.
    • (1997) Gene Ther , vol.4 , pp. 577-585
    • Vrionis, F.D.1    Wu, J.K.2    Qi, P.3    Waltzman, M.4    Cherington, V.5    Spray, D.C.6
  • 37
    • 0032929652 scopus 로고    scopus 로고
    • Connexins are expressed in primary brain tumors and enhance the bystander effect in gene therapy.
    • discussion
    • Estin D, Li M, Spray D, Wu JK. Connexins are expressed in primary brain tumors and enhance the bystander effect in gene therapy. Neurosurgery 1999, 44:361-368, discussion.
    • (1999) Neurosurgery , vol.44 , pp. 361-368
    • Estin, D.1    Li, M.2    Spray, D.3    Wu, J.K.4
  • 40
    • 0030724139 scopus 로고    scopus 로고
    • Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes.
    • Denning C, Pitts JD. Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes. Hum Gene Ther 1997, 8:1825-1835.
    • (1997) Hum Gene Ther , vol.8 , pp. 1825-1835
    • Denning, C.1    Pitts, J.D.2
  • 42
    • 80755132075 scopus 로고    scopus 로고
    • Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect.
    • Preuss E, Muik A, Weber K, Otte J, von Laer D, Fehse B. Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect. J Mol Med (Berl) 2011, 89:1113-1124.
    • (2011) J Mol Med (Berl) , vol.89 , pp. 1113-1124
    • Preuss, E.1    Muik, A.2    Weber, K.3    Otte, J.4    von Laer, D.5    Fehse, B.6
  • 43
    • 0037646985 scopus 로고    scopus 로고
    • Besides affecting intracellular calcium signaling, 2-APB reversibly blocks gap junctional coupling in confluent monolayers, thereby allowing measurement of single-cell membrane currents in undissociated cells.
    • Harks EG, Camina JP, Peters PH, Ypey DL, Scheenen WJ, van Zoelen EJ, Theuvenet AP. Besides affecting intracellular calcium signaling, 2-APB reversibly blocks gap junctional coupling in confluent monolayers, thereby allowing measurement of single-cell membrane currents in undissociated cells. FASEB J 2003, 17:941-943.
    • (2003) FASEB J , vol.17 , pp. 941-943
    • Harks, E.G.1    Camina, J.P.2    Peters, P.H.3    Ypey, D.L.4    Scheenen, W.J.5    van Zoelen, E.J.6    Theuvenet, A.P.7
  • 44
    • 33751173225 scopus 로고    scopus 로고
    • Block of specific gap junction channel subtypes by 2-aminoethoxydiphenyl borate (2-APB).
    • Bai D, del Corsso C, Srinivas M, Spray DC. Block of specific gap junction channel subtypes by 2-aminoethoxydiphenyl borate (2-APB). J Pharmacol Exp Ther 2006, 319:1452-1458.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 1452-1458
    • Bai, D.1    del Corsso, C.2    Srinivas, M.3    Spray, D.C.4
  • 46
    • 78649380201 scopus 로고    scopus 로고
    • Cell-cell propagation of NF-κB transcription factor and MAP kinase activation amplifies innate immunity against bacterial infection.
    • Kasper CA, Sorg I, Schmutz C, Tschon T, Wischnewski H, Kim ML, Arrieumerlou C. Cell-cell propagation of NF-κB transcription factor and MAP kinase activation amplifies innate immunity against bacterial infection. Immunity 2010, 33:804-816.
    • (2010) Immunity , vol.33 , pp. 804-816
    • Kasper, C.A.1    Sorg, I.2    Schmutz, C.3    Tschon, T.4    Wischnewski, H.5    Kim, M.L.6    Arrieumerlou, C.7
  • 47
    • 0043198046 scopus 로고    scopus 로고
    • Connexin-dependent inter-cellular communication increases invasion and dissemination of Shigella in epithelial cells.
    • Tran Van Nhieu G, Clair C, Bruzzone R, Mesnil M, Sansonetti P, Combettes L. Connexin-dependent inter-cellular communication increases invasion and dissemination of Shigella in epithelial cells. Nat Cell Biol 2003, 5:720-726.
    • (2003) Nat Cell Biol , vol.5 , pp. 720-726
    • Tran Van Nhieu, G.1    Clair, C.2    Bruzzone, R.3    Mesnil, M.4    Sansonetti, P.5    Combettes, L.6
  • 48
    • 63249111750 scopus 로고    scopus 로고
    • Reciprocal influence of connexins and apical junction proteins on their expressions and functions.
    • Derangeon M, Spray DC, Bourmeyster N, Sarrouilhe D, Herve JC. Reciprocal influence of connexins and apical junction proteins on their expressions and functions. Biochim Biophys Acta 2009, 1788:768-778.
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 768-778
    • Derangeon, M.1    Spray, D.C.2    Bourmeyster, N.3    Sarrouilhe, D.4    Herve, J.C.5
  • 49
    • 36348983398 scopus 로고    scopus 로고
    • Gap junctions mediate human immunodeficiency virus-bystander killing in astrocytes.
    • Eugenin EA, Berman JW. Gap junctions mediate human immunodeficiency virus-bystander killing in astrocytes. J Neurosci Off J Soc Neurosci 2007, 27:12844-12850.
    • (2007) J Neurosci Off J Soc Neurosci , vol.27 , pp. 12844-12850
    • Eugenin, E.A.1    Berman, J.W.2
  • 50
    • 79960003831 scopus 로고    scopus 로고
    • Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanism.
    • Eugenin EA, Clements JE, Zink MC, Berman JW. Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanism. J Neurosci Off J Soc Neurosci 2011, 31:9456-9465.
    • (2011) J Neurosci Off J Soc Neurosci , vol.31 , pp. 9456-9465
    • Eugenin, E.A.1    Clements, J.E.2    Zink, M.C.3    Berman, J.W.4
  • 54
    • 0034763554 scopus 로고    scopus 로고
    • Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability.
    • Barcellos-Hoff MH, Brooks AL. Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability. Radiat Res 2001, 156:618-627.
    • (2001) Radiat Res , vol.156 , pp. 618-627
    • Barcellos-Hoff, M.H.1    Brooks, A.L.2
  • 55
    • 0031936163 scopus 로고    scopus 로고
    • Cell-cell contact during γ irradiation is not required to induce a bystander effect in normal human keratinocytes: evidence for release during irradiation of a signal controlling survival into the medium.
    • Mothersill C, Seymour CB. Cell-cell contact during γ irradiation is not required to induce a bystander effect in normal human keratinocytes: evidence for release during irradiation of a signal controlling survival into the medium. Radiat Res 1998, 149:256-262.
    • (1998) Radiat Res , vol.149 , pp. 256-262
    • Mothersill, C.1    Seymour, C.B.2
  • 56
    • 0031770716 scopus 로고    scopus 로고
    • Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles.
    • Azzam EI, de Toledo SM, Gooding T, Little JB. Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles. Radiat Res 1998, 150:497-504.
    • (1998) Radiat Res , vol.150 , pp. 497-504
    • Azzam, E.I.1    de Toledo, S.M.2    Gooding, T.3    Little, J.B.4
  • 57
    • 0035895240 scopus 로고    scopus 로고
    • Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha -particle irradiated to nonirradiated cells.
    • Azzam EI, de Toledo SM, Little JB. Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha -particle irradiated to nonirradiated cells. Proc Natl Acad Sci U S A 2001, 98:473-478.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 473-478
    • Azzam, E.I.1    de Toledo, S.M.2    Little, J.B.3
  • 58
    • 0036023759 scopus 로고    scopus 로고
    • Early events in the apoptotic cascade initiated in cells treated with medium from the progeny of irradiated cells.
    • Lyng FM, Seymour CB, Mothersill C. Early events in the apoptotic cascade initiated in cells treated with medium from the progeny of irradiated cells. Radiat Prot Dosimetry 2002, 99:169-172.
    • (2002) Radiat Prot Dosimetry , vol.99 , pp. 169-172
    • Lyng, F.M.1    Seymour, C.B.2    Mothersill, C.3
  • 59
    • 0036844379 scopus 로고    scopus 로고
    • Bystander and delayed effects after fractionated radiation exposure.
    • Mothersill C, Seymour CB. Bystander and delayed effects after fractionated radiation exposure. Radiat Res 2002, 158:626-633.
    • (2002) Radiat Res , vol.158 , pp. 626-633
    • Mothersill, C.1    Seymour, C.B.2
  • 61
    • 0348048742 scopus 로고    scopus 로고
    • Cell proximity is a prerequisite for the proliferative response of bystander cells co-cultured with cells irradiated with γ-rays.
    • Gerashchenko BI, Howell RW. Cell proximity is a prerequisite for the proliferative response of bystander cells co-cultured with cells irradiated with γ-rays. Cytometry A 2003, 56:71-80.
    • (2003) Cytometry A , vol.56 , pp. 71-80
    • Gerashchenko, B.I.1    Howell, R.W.2
  • 62
    • 35748982399 scopus 로고    scopus 로고
    • Isoform-specific activation of protein kinase c in irradiated human fibroblasts and their bystander cells.
    • Baskar R, Balajee AS, Geard CR, Hande MP. Isoform-specific activation of protein kinase c in irradiated human fibroblasts and their bystander cells. Int J Biochem Cell Biol 2008, 40:125-134.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 125-134
    • Baskar, R.1    Balajee, A.S.2    Geard, C.R.3    Hande, M.P.4
  • 63
    • 77953141396 scopus 로고    scopus 로고
    • Induction of bystander response in human glioma cells using high-energy electrons: a role for TGF-β1.
    • Gow MD, Seymour CB, Ryan LA, Mothersill CE. Induction of bystander response in human glioma cells using high-energy electrons: a role for TGF-β1. Radiat Res 2010, 173:769-778.
    • (2010) Radiat Res , vol.173 , pp. 769-778
    • Gow, M.D.1    Seymour, C.B.2    Ryan, L.A.3    Mothersill, C.E.4
  • 64
    • 0242658543 scopus 로고    scopus 로고
    • Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation?
    • Morgan WF. Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation? Oncogene 2003, 22:7094-7099.
    • (2003) Oncogene , vol.22 , pp. 7094-7099
    • Morgan, W.F.1
  • 66
    • 84872102097 scopus 로고    scopus 로고
    • Involvement of connexin43 hemichannel in ATP release after γ-irradiation.
    • Ohshima Y, Tsukimoto M, Harada H, Kojima S. Involvement of connexin43 hemichannel in ATP release after γ-irradiation. J Radiat Res 2012, 53:551-557.
    • (2012) J Radiat Res , vol.53 , pp. 551-557
    • Ohshima, Y.1    Tsukimoto, M.2    Harada, H.3    Kojima, S.4
  • 67
    • 84865631821 scopus 로고    scopus 로고
    • Gap junctions, stem cells, and cell therapy: rhythmic/arrhythmic implications.
    • Maizels L, Gepstein L. Gap junctions, stem cells, and cell therapy: rhythmic/arrhythmic implications. Heart Rhythm 2011, 9:1512-1516.
    • (2011) Heart Rhythm , vol.9 , pp. 1512-1516
    • Maizels, L.1    Gepstein, L.2
  • 71
    • 0035478279 scopus 로고    scopus 로고
    • Global ischemia-induced increases in the gap junctional proteins connexin 32 (Cx32) and Cx36 in hippocampus and enhanced vulnerability of Cx32 knock-out mice.
    • Oguro K, Jover T, Tanaka H, Lin Y, Kojima T, Oguro N, Grooms SY, Bennett MV, Zukin RS. Global ischemia-induced increases in the gap junctional proteins connexin 32 (Cx32) and Cx36 in hippocampus and enhanced vulnerability of Cx32 knock-out mice. J Neurosci Off J Soc Neurosci 2001, 21:7534-7542.
    • (2001) J Neurosci Off J Soc Neurosci , vol.21 , pp. 7534-7542
    • Oguro, K.1    Jover, T.2    Tanaka, H.3    Lin, Y.4    Kojima, T.5    Oguro, N.6    Grooms, S.Y.7    Bennett, M.V.8    Zukin, R.S.9
  • 72
    • 0034576040 scopus 로고    scopus 로고
    • Reciprocal regulation of the junctional proteins claudin-1 and connexin43 by interleukin-1β in primary human fetal astrocytes.
    • Duffy HS, John GR, Lee SC, Brosnan CF, Spray DC. Reciprocal regulation of the junctional proteins claudin-1 and connexin43 by interleukin-1β in primary human fetal astrocytes. J Neurosci 2000, 20:RC114.
    • (2000) J Neurosci , vol.20
    • Duffy, H.S.1    John, G.R.2    Lee, S.C.3    Brosnan, C.F.4    Spray, D.C.5
  • 73
    • 0027277119 scopus 로고
    • Facial nerve lesions lead to increased immunostaining of the astrocytic gap junction protein (connexin 43) in the corresponding facial nucleus of rats.
    • Rohlmann A, Laskawi R, Hofer A, Dobo E, Dermietzel R, Wolff JR. Facial nerve lesions lead to increased immunostaining of the astrocytic gap junction protein (connexin 43) in the corresponding facial nucleus of rats. Neurosci Lett 1993, 154:206-208.
    • (1993) Neurosci Lett , vol.154 , pp. 206-208
    • Rohlmann, A.1    Laskawi, R.2    Hofer, A.3    Dobo, E.4    Dermietzel, R.5    Wolff, J.R.6
  • 74
    • 3242660930 scopus 로고    scopus 로고
    • The effects of axotomy on neurons and satellite glial cells in mouse trigeminal ganglion.
    • Cherkas PS, Huang TY, Pannicke T, Tal M, Reichenbach A, Hanani M. The effects of axotomy on neurons and satellite glial cells in mouse trigeminal ganglion. Pain 2004, 110:290-298.
    • (2004) Pain , vol.110 , pp. 290-298
    • Cherkas, P.S.1    Huang, T.Y.2    Pannicke, T.3    Tal, M.4    Reichenbach, A.5    Hanani, M.6
  • 75
  • 77
    • 0036159649 scopus 로고    scopus 로고
    • Blocked gap junctional coupling increases glutamate-induced neurotoxicity in neuron-astrocyte co-cultures.
    • Ozog MA, Siushansian R, Naus CC. Blocked gap junctional coupling increases glutamate-induced neurotoxicity in neuron-astrocyte co-cultures. J Neuropathol Exp Neurol 2002, 61:132-141.
    • (2002) J Neuropathol Exp Neurol , vol.61 , pp. 132-141
    • Ozog, M.A.1    Siushansian, R.2    Naus, C.C.3
  • 79
    • 70849099466 scopus 로고    scopus 로고
    • Cx43 CT domain influences infarct size and susceptibility to ventricular tachyarrhythmias in acute myocardial infarction.
    • Maass K, Chase SE, Lin X, Delmar M. Cx43 CT domain influences infarct size and susceptibility to ventricular tachyarrhythmias in acute myocardial infarction. Cardiovasc Res 2009, 84:361-367.
    • (2009) Cardiovasc Res , vol.84 , pp. 361-367
    • Maass, K.1    Chase, S.E.2    Lin, X.3    Delmar, M.4
  • 80
    • 0034879017 scopus 로고    scopus 로고
    • Effective reduction of neuronal death by inhibiting gap junctional intercellular communication in a rodent model of global transient cerebral ischemia.
    • Rami A, Volkmann T, Winckler J. Effective reduction of neuronal death by inhibiting gap junctional intercellular communication in a rodent model of global transient cerebral ischemia. Exp Neurol 2001, 170:297-304.
    • (2001) Exp Neurol , vol.170 , pp. 297-304
    • Rami, A.1    Volkmann, T.2    Winckler, J.3
  • 81
    • 0030669472 scopus 로고    scopus 로고
    • Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke.
    • Rawanduzy A, Hansen A, Hansen TW, Nedergaard M. Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke. J Neurosurg 1997, 87:916-920.
    • (1997) J Neurosurg , vol.87 , pp. 916-920
    • Rawanduzy, A.1    Hansen, A.2    Hansen, T.W.3    Nedergaard, M.4
  • 82
  • 83
    • 0029063571 scopus 로고
    • Halothane reduces focal ischemic injury in the rat when brain temperature is controlled.
    • discussion 27A
    • Warner DS, Ludwig PS, Pearlstein R, Brinkhous AD. Halothane reduces focal ischemic injury in the rat when brain temperature is controlled. Anesthesiology 1995, 82:1237-1245, discussion 27A.
    • (1995) Anesthesiology , vol.82 , pp. 1237-1245
    • Warner, D.S.1    Ludwig, P.S.2    Pearlstein, R.3    Brinkhous, A.D.4
  • 85
    • 34548557257 scopus 로고    scopus 로고
    • Protection from ataxia-linked apoptosis by gap junction inhibitors.
    • Lin D, Takemoto DJ. Protection from ataxia-linked apoptosis by gap junction inhibitors. Biochem Biophys Res Commun 2007, 362:982-987.
    • (2007) Biochem Biophys Res Commun , vol.362 , pp. 982-987
    • Lin, D.1    Takemoto, D.J.2
  • 86
    • 1142297603 scopus 로고    scopus 로고
    • Gap junction-mediated spread of cell injury and death during myocardial ischemia-reperfusion.
    • Garcia-Dorado D, Rodriguez-Sinovas A, Ruiz-Meana M. Gap junction-mediated spread of cell injury and death during myocardial ischemia-reperfusion. Cardiovasc Res 2004, 61:386-401.
    • (2004) Cardiovasc Res , vol.61 , pp. 386-401
    • Garcia-Dorado, D.1    Rodriguez-Sinovas, A.2    Ruiz-Meana, M.3
  • 87
    • 75349099752 scopus 로고    scopus 로고
    • Role of gap junctions in early brain injury following subarachnoid hemorrhage.
    • Ayer R, Chen W, Sugawara T, Suzuki H, Zhang JH. Role of gap junctions in early brain injury following subarachnoid hemorrhage. Brain Res 2010, 1315:150-158.
    • (2010) Brain Res , vol.1315 , pp. 150-158
    • Ayer, R.1    Chen, W.2    Sugawara, T.3    Suzuki, H.4    Zhang, J.H.5
  • 90
    • 33748681711 scopus 로고    scopus 로고
    • Gap junctions remain open during cytochrome c-induced cell death: relationship of conductance to 'bystander' cell killing.
    • Cusato K, Ripps H, Zakevicius J, Spray DC. Gap junctions remain open during cytochrome c-induced cell death: relationship of conductance to 'bystander' cell killing. Cell Death Differ 2006, 13:1707-1714.
    • (2006) Cell Death Differ , vol.13 , pp. 1707-1714
    • Cusato, K.1    Ripps, H.2    Zakevicius, J.3    Spray, D.C.4
  • 91
    • 0036351963 scopus 로고    scopus 로고
    • Cell death in retinitis pigmentosa: gap junctions and the 'bystander' effect.
    • Ripps H. Cell death in retinitis pigmentosa: gap junctions and the 'bystander' effect. Exp Eye Res 2002, 74:327-336.
    • (2002) Exp Eye Res , vol.74 , pp. 327-336
    • Ripps, H.1
  • 93
    • 24644508371 scopus 로고    scopus 로고
    • The spread of apoptosis through gap-junctional channels in BHK cells transfected with Cx32.
    • Udawatte C, Ripps H. The spread of apoptosis through gap-junctional channels in BHK cells transfected with Cx32. Apoptosis 2005, 10:1019-1029.
    • (2005) Apoptosis , vol.10 , pp. 1019-1029
    • Udawatte, C.1    Ripps, H.2
  • 95
    • 33646584876 scopus 로고    scopus 로고
    • Ischemia opens neuronal gap junction hemichannels.
    • Thompson RJ, Zhou N, MacVicar BA. Ischemia opens neuronal gap junction hemichannels. Science 2006, 312:924-927.
    • (2006) Science , vol.312 , pp. 924-927
    • Thompson, R.J.1    Zhou, N.2    MacVicar, B.A.3
  • 97
    • 59649095837 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase type II inhibition causes cerebrovascular remodeling and increases infarct size after cerebral ischemia.
    • Osmond JM, Dorrance AM. 11β-Hydroxysteroid dehydrogenase type II inhibition causes cerebrovascular remodeling and increases infarct size after cerebral ischemia. Endocrinology 2009, 150:713-719.
    • (2009) Endocrinology , vol.150 , pp. 713-719
    • Osmond, J.M.1    Dorrance, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.