Designing studies and rodent models for studying prebiotics for colorectal cancer prevention

Handbook of Prebiotics

Volumn , Issue , 2008, Pages 263-284

  Asad, Umar ^a   Emenaker, Nancy J ^a   Milner, John A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84926523841     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (86)

1. Rat Genome Sequencing Project Consortium, Genome sequence of the Brown Norway rat yields insights into mammalian evolution, Nature, 428, 493, 2004.
2. Weil, M.M. et al., Strain difference in jejunal crypt cell susceptibility to radiation-induced apoptosis, Int. J. Radiat. Biol., 70, 579,1996.
3. Weil, M.M. et al., A chromosome 15 quantitative trait locus controls levels of radiation-induced jejunal crypt cell apoptosis in mice, Genomics, 72, 73, 2001.
4. Weiss, B. and Shannon, K., Mouse cancer models as a platform for performing preclinical therapeutic trials, Curr. Opin. Genet. Dev., 13, 84, 2003.
5. Sharpless, N.E. and DePinho, R.A., The mighty mouse: Genetically engineered. Nat rev Drug Discov. 5, 741, 2006.
6. Pollard, M. and Suckow, M.A., Dietary prevention of hormone refractory prostate cancer in Lobund-Wistar rats: A review of studies in a relevant animal model, Comp. Med., 56, 461,2006.
7. Anderson, L.M., Environmental genotoxicants/carcinogens and childhood cancer: Bridgeable gaps in scientific knowledge, Mutat. Res., 608,136, 2006.
8. Rangarajan, A. and Weinberg, R.A., Comparative biology of mouse versus human cells: Modelling human cancer in mice, Nat. Rev. Cancer, 3, 952, 2003.
9. Corpet, D.E. and Pierre, F., Point: From animal models to prevention of colon cancer, Systematic review of chemoprevention in min mice and choice of the model system, Cancer Epidemiol. Biomarkers Prev. 12, 391, 2003.
10. Corpet, D.E. and Pierre, F., How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men, Eur. J. Cancer, 41, 1911,2005.
11. Yu, C.F. et al., Differential dietary effects on colonic and small bowel neoplasia in C57BL/6J Apc Min/+ mice, Dig. Dis. Sci., 46, 1367,2001.
12. Sieber, O.M. et al., Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice, Cancer Res., 64, 8876,2004.
13. Nambiar, P.R. et al., Preliminary analysis of azoxymethane induced colon tumors in inbred mice commonly used as transgenic/knockout progenitors, Int. J. Oncol., 22,145, 2003.
14. Bissahoyo, A. et al., Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: Effects of dose, route, and diet, Toxicol. Sci., 88, 340,2005.
15. Moser, A.R., Pitot, H.C. and Dove, W.F., A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse, Science, 247, 322,1990.
16. Moser, A.R. et al., The Min (multiple intestinal neoplasia) mutation: Its effect on gut epithelial cell differentiation and interaction with a modifier system, J. Cell Biol., 116, 1517,1992.
17. Su, L.K. et al., Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene, Science, 256, 668, 1992.
18. Luongo, C. et al., Loss of Apc+ in intestinal adenomas from Min mice, Cancer Res, 54, 5947, 1994.
19. Segditsas, S. and Tomlinson, I., Colorectal cancer and genetic alterations in the Wnt pathway, Oncogene, 25, 753, 2006.
20. Taketo, M.M., Wnt signaling and gastrointestinal tumorigenesis in mouse models, Oncogene, 25, 7522, 2006.
21. Dietrich, W.F. et al., Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse, Cell, 75, 631, 1993.
22. van der Houven, van Oordt, C.W. et al., The genetic background modifies the spontaneous and X-ray-induced tumor spectrum in the Apc1638N mouse model, Genes Chromosomes. Cancer, 24, 191, 1999.
23. Manenti, G. et al., Genetic mapping of lung cancer modifier loci specifically affecting tumor initiation and progression, Cancer Res., 57,4164, 1997.
24. Castegnaro, M. et al., Sex- and strain-specific induction of renal tumors by ochratoxin A in rats correlates with DNA adduction, Int. J. Cancer, 77, 70, 1998.
25. Kodama, Y. et al., The D5Mit7 locus on mouse chromosome 5 provides resistance to gamma-ray-induced but not N-methyl-N-nitrosourea-induced thymic, Carcinogenesis, 25, 143, 2004.
26. Tsukamoto, T. et al., Susceptibility to colon carcinogenesis in C3H C57BL/6 chimeric mice reflects both tissue microenvironment and genotype, Cancer Lett., 239, 205, 2006.
27. Dunson, D.B. and Dinse, G.E., Distinguishing effects on tumor multiplicity and growth rate in chemoprevention experiments, Biometrics, 56, 1068, 2000.
28. Moriya, M. et al., Detection of mutagenicity of the colon carcinogen 1,2-dimethylhydrazine by the host-mediated assay and its correlation to carcinogenicity, J. Natl. Cancer Inst., 61, 457, 1978.
29. Delker, D.A., Bammler, T.K. and Rosenberg, D.W., A comparative study of hepatic and colonic metabolic enzymes in inbred mouse lines before and after treatment with the colon carcinogen, 1,2-dimethylhydrazine, Drug Metab. Dispos., 24, 408,1996.
30. Papanikolaou, A. et al., Azoxymethane-induced colon tumors and aberrant crypt foci in mice of different genetic susceptibility, Cancer Lett., 130, 29, 1998.
31. Pereira, M.A. et al., Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents, Carcinogenesis, 15, 1049, 1994.
32. Felton, J.S. et al., The isolation and identification of a new mutagen from fried ground beef: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), Carcinogenesis, 7, 1081, 1986.
33. Felton, J.S. et al., Mutagenic activity of heterocyclic amines in cooked foods, Environ. Health Perspect., 102, 201, 1994.
34. Gross, G.A. et al., Heterocyclic aromatic amine formation in grilled bacon, beef and fish and in grill scrapings, Carcinogenesis, 14, 2313, 1993.
35. Kikugawa, K., Kato, T. and Takahashi, S., Possible presence of 2-amino-3,4- dimethylimidazo[4,5-f]quinoline and other heterocyclic amines in roasted coffee beans, J. Agric, Food Chem., 37, 881, 1989.
36. Nakagama, H., Nakanishi, M. and Ochiai, M., Modeling human colon cancer in rodents using a food-borne carcinogen PhIP, Cancer Sci., 96, 627, 2005.
37. Ishiguro, Y., Strain differences of rats in the susceptibility to aberrant crypt foci formation by 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine: No implication of Apc and Pla2g2a genetic polymorphisms in differential susceptibility, Carcinogenesis, 20,1063, 1999.
38. Purewal, M. et al., 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine induces a higher number of aberrant crypt foci in Fischer 344 (rapid) than in Wistar Kyoto (slow) acetylator inbred rats, Cancer Epidemiol. Biomarkers Prev., 9, 529, 2000.
39. Tudek, B., Bird, R.P. and Bruce, W.R., Foci of aberrant crypts in the colons of mice and rats exposed to carcinogens associated with foods, Cancer Res., 49, 1236, 1989.
40. Shoemaker, A.R. et al., Studies of neoplasia in the Min mouse, Biochim. Biophys. Acta, 1332, F25,1997.
41. Shoemaker, A.R. et al., A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice, Proc. Natl. Acad. Sci. USA, 95, 10826, 1998.
42. Gould, K.A. and Dove, W.F., Action of Min and Mom1 on neoplasia in ectopic intestinal grafts, Cell Growth Differ, 7, 1361, 1996.
43. Soto, A.M. and Sonnenschein, C., The somatic mutation theory of cancer: Growing problems with the paradigm? BioEssays, 26,1097, 2004.
44. Wicha, M.S. and Dontu, D., Cancer stem cells: An old idea—a paradigm shift, Cancer Res, 66, 1883, 2006.
45. Dolle, M.E.T. et al., Mutational fingerprints of aging, Nucleic Acids Res., 30, 545, 2002.
46. McGarrity, T.J. et al., Effects of fat and fiber on human colon cancer xenografted to athymic nude mice, Dig. Dis. Sci., 36, 1606,1991.
47. Guarner, F., Enteric flora in health and disease, Digestion, 73, 5, 2006.
48. Guarner, F. and Malagelada, J.-R., Gut flora in health and disease, Lancet, 361, 512,2003.
49. Gibson, G.R. and Roberfroid, M.B., Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics, J. Nutr., 125, 1401, 1995.
50. Madsen, K.L. et al., Lactobacillus species prevents colitis in interleukin 10 gene-deficient mice, Gastroenterology, 116, 1107, 1999.
51. Tanabe, H., Dietary indigestible components exert different regional effects on luminal mucin secretion through their bulk-forming property and fermentabil-ity, Biosci. Biotechnol. Biochem., 70, 1188,2006.
52. Pavan, S., Desreumaux, P. and Mercenier, A., Use of mouse models to evaluate the persistence, safety, and immune modulation capacities of lactic acid bacteria, Clin. Diag. Lab. Immunol., 10, 696,2003.
53. Fujiwara, M. et al., Inhibitory effects of Bifidobacterium longum on experimental ulcerative colitis induced in mice by synthetic dextran sulfate sodium, Digestion, 67, 90, 2003.
54. Attene-Ramos, M.S. et al., Evidence that hydrogen sulfide is a genotoxic agent, Mol. Cancer Res., 4, 9, 2006.
55. Titgemeyer, E.C. et al., Fermentability of various fiber sources by human fecal bacteria in vitro. Am. J. Clin. Nutr., 53,1418, 1991.
56. Stark, A.H. and Madar, Z., In vitro production of short-chain fatty acids by bacterial fermentation of dietary fiber compared with effects of those fibers on hepatic sterol synthesis in rats, J. Nutr., 123, 2166, 1993.
57. Nilsson, U. and Nyman, M., Short-chain fatty acid formation in the hindgut of rats fed oligosaccharides varying in monomeric composition, degree of polymerisation and solubility, Br. J. Nutr., 94, 705, 2005.
58. Cummings, J.H. et al., Short chain fatty acids in human large intestine, portal, hepatic and venous blood, Gut, 28,1221,1987.
59. Harig, J.M. et al., Treatment of diversion colitis with short-chain-fatty acid irrigation, N. Engl. J. Med, 320, 23, 1989.
60. Report of the Dietary Fiber Definition Committee to the Board of Directors of the American Association of Cereal Chemists, Cereal Foods World, 46, 112, 2001.
61. Yao, H.T. and Chiang, M.T. Chitosan shifts the fermentation site toward the distal colon and increases the fecal short-chain fatty acids concentrations in rats, Int. J. Vitam. Nutr. Res., 76, 57,2006.
62. Sakamoto, J. et al., Comparison of resistant starch with cellulose diet on 1,2-dimethylhydrazine-induced colonic carcinogenesis in rats, Gastroenterology, 110, 116,1996.
63. Perrin, P. et al., Only fibres promoting a stable butyrate producing colonic ecosystem decrease the rate of aberrant crypt foci in rats, Gut, 48, 53, 2001.
64. Compher, C.W. et al., Wheat bran decreases aberrant crypt foci, preserves normal proliferation, and increases intraluminal butyrate levels in experimental colon cancer, J. Parenter. Enteral. Nutr., 23, 269, 1999.
65. Iwane, S. et al., Inhibitory effect of small amounts of cellulose on colonic, Dig Dis Sci, 47, 1257, 2002.
66. Yang, Y. and Gallaher, D.D., Effect of dried plums on colon cancer risk factors in rats, Nutr. Cancer, 53,117, 2005.
67. Zoran, D.L. et al., Wheat bran diet reduces tumor incidence in a rat model of colon cancer independent of effects on distal luminal butyrate concentrations, J.Nutr., 127, 2217,1997.
68. Heitman, D.W. et al., Effect of dietary cellulose on cell proliferation and progression of 1,2-dimethylhydrazine-induced colon carcinogenesis in rats, Cancer Res., 49, 5581, 1989.
69. Jiang, Y.H., Lupton, J.R. and Chapkin, R.S., Dietary fat and fiber modulate the effect of carcinogen on colonic protein kinase C lambda expression in rats, J.Nutr., 127, 1938, 1997.
70. Yu, Y. et al., Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) gene, Cancer Res., 61, 1820, 2001.
71. Institute of Medicine. In Dietary Reference Intakes: Proposed Definition of Dietary Fiber, 2001, 48, The National Academies Press, Washington, DC.
72. Topping, D.L. and Clifton, P.M., Short-chain fatty acids and human colonic function: Roles of resistant starch and nonstarch polysaccharides, Physiol. Rev., 81, 1031,2001.
73. Le Leu, R.K. et al., Effect of dietary resistant starch and protein on colonic fermentation and intestinal tumourigenesis in rats, Carcinogenesis, 28,240,2007.
74. Lin, H.C. and Visek, W.J., Colon mucosal cell damage by ammonia in rats, J.Nutr., 121, 887,1991.
75. Bauer-Marinovic, M. et al., Dietary resistant starch type 3 prevents tumor induction by 1,2-dimethylhydrazine and alters proliferation, apoptosis and dedifferentiation in rat colon, Carcinogenesis, 27,1849, 2006.
76. Langlands, S.J. et al., Prebiotic carbohydrates modify the mucosa associated microflora of the human large bowel, Gut, 53, 1610, 2004.
77. Kleessen, B., Hartmann, L. and Blaut, M., Oligofructose and long-chain inulin: Influence on the gut microbial ecology of rats associated with a human faecal flora, Br. J. Nutr., 86, 291,2001.
78. Hsu, C.-K. et al., Xylooligosaccharides and fructooligosaccharides affect the intestinal microbiota and precancerous colonic lesion development in rats, J. Nutr., 134, 1523, 2004.
79. Ten Bruggencate, S.J. et al., Dietary fructooligosaccharides increase intestinal permeability in rats, J. Nutr., 135, 837, 2005.
80. Hughes, R. and Rowland, I.R., Stimulation of apoptosis by two prebiotic chicory fructans in the rat colon, Carcinogenesis, 22, 43, 2001.
81. Bovee-Oudenhoven, I.M. et al., Dietary fructo-oligosaccharides and lactulose inhibit intestinal colonisation but stimulate translocation of salmonella in rats, Gut, 52, 1572, 2003.
82. Ten Bruggencate, S.J. et al., Dietary fructo-oligosaccharides dose-dependently increase translocation of salmonella in rats, J. Nutr., 133, 2313, 2003.
83. Wijnands, M.V. et al., A comparison of the effects of dietary cellulose and fermentable galacto-oligosaccharide, in a rat model of colorectal carcinogenesis: Fermentable fibre confers greater protection than non-fermentable fibre in both high and low fat backgrounds, Carcinogenesis, 20, 651, 1999.
84. Wijnands, M.V. et al., Effect of dietary galacto-oligosaccharides on azoxymethane-induced aberrant crypt foci and colorectal cancer in Fischer 344 rats carcinogenesis. 22, 107, 2001.
85. Campbell, J.M., Fahey, G.C. Jr. and Wolf, B.W., Selected indigestible oligosaccharides affect large bowel mass, cecal and fecal short-chain fatty acids, pH and microflora in rats, J. Nutr, 127,130, 1997.
86. Santos, A., San Mauro, M. and Diaz, D.M., Prebiotics and their long-term influence on the microbial populations of the mouse bowel, Food Microbiol., 23, 498, 2006.