Selected indigestible oligosaccharides affect large bowel mass, cecal and fecal short-chain fatty acids, pH and microflora in rats

Journal of Nutrition

Volumn 127, Issue 1, 1997, Pages 130-136

  Campbell, Joy M ^a   Fahey Jr , George C ^a   Wolf, Bryan W ^b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

bifidobacteria; oligosaccharides; rats; short chain fatty acids

Indexed keywords

OLIGOSACCHARIDE; SHORT CHAIN FATTY ACID;

ANIMAL EXPERIMENT; ARTICLE; COLON FLORA; CONTROLLED STUDY; DIET; DIETARY FIBER; DIGESTION; FERMENTATION; FOOD COMPOSITION; MALE; NONHUMAN; PH; RAT;

ANIMALIA; BACTERIA (MICROORGANISMS); MICROBIOTA;

EID: 0031023319     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/127.1.130     Document Type: Article

References (31)

1. Barker, S. B. & Summerson, W. H. (1941) The colorimetric determination of lactic acid in biological material. J. Biol. Chem. 138: 535-554.
2. Berggren, A. M., Bjorck, I.M.E., Margareta, E., Nyman, G. L. & Eggum, B. O. (1993) Short-chain fatty acid content and pH in caecum of rats given various sources of carbohydrates. J. Sci. Food Agric. 63: 397-406.
3. Bryant, M. P. & Burkey, L. A. (1953) Cultural methods and some characteristics of some of the more numerous groups of bacteria in the bovine rumen. J. Dairy Sci. 36: 205-217.
4. Bryant, M. P. & Robinson, I. M. (1961) An improved nonselective culture medium for ruminai bacteria and its use in determining diurnal variation in numbers of bacteria in the rumen. J. Dairy Sci. 44: 1446-1456.
5. Carmer, S. G. & Swanson, M. R. (1973) An evaluation of ten pairwise multiple comparison procedures by Monte Carlo methods. J. Am. Stat. Assoc. 68: 66-74.
6. Erwin, E. S., Marco, G. J. & Emery, E. M. (1961) Volatile fatty acid analyses of blood and rumen fluid by gas chromatography. J. Dairy Sci. 44: 1768-1771.
7. Frankel, W. L., Zhang, W., Singh, A., Klurfeld, D. M., Don, S., Sakata, T., Modlin, I. & Rombeau, J. L. (1994) Mediation of the trophic effects of short-chain fatty acids on the rat jejunum and colon. Gastroenterology 106: 375-380.
8. Gibson, G. R., Beatty, E. R., Wang, X. & Cummings, J. H. (1995) Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterology 108: 975-982.
9. Gibson, G. R. & Roberfroid, M. B. (1995) Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J. Nutr. 125: 1401-1412.
10. Gibson, G. R. & Wang, X. (1994) Regulatory effects of bifidobacteria on the growth of other colonic bacteria. J. Appl. Bacteriol. 77: 412-420.
11. Harig, J. M., Soergel, K. H., Komorowski, R. A. & Wood, C. M. (1989) Treatment of diversion colitis with short-chain-fatty acid irrigation. N. Engl. J. Med. 320: 23-28.
12. Hidaka, H., Eida, T., Takizawa, T., Tokunaga, T. & Tashiro, Y. (1986) Effects of fructooligosaccharides on intestinal flora and human health. Bifidobact. Microflora 5: 37-50.
13. Hidaka, H., Hirayama, M. & Yamada, K. (1991a) Fructooligosaccharides enzymatic preparation and biofunctions. J. Carbohydr. Chem. 10: 509-522.
14. Hidaka, H., Tashiro, Y. & Eida, T. (1991b) Proliferation of bifidobacteria by oligosaccharides and their useful effect on human health. Bifidobact. Microflora 10: 65-79.
15. Koruda, M. J., Rolandelli, R. H. & Settle, R. G. (1988) Effect of parenteral nutrition supplemented with short-chain fatty acids on adaption to massive small bowel resection. Gastroenterology 95: 715-720.
16. Kripke, S. A., Fox, A. D., Berman, J. M., Settle, R. G. & Rombeau, J. L. (1989) Stimulation of intestinal mucosal growth with intracolonic infusion of short-chain fatty acids. J. Parent. Enteral Nutr. 13: 109-116.
17. Levrat, M. A., Rémésy, C. & Demigné, C. (1991) High propionic acid fermentations and mineral accumulation in the cecum of rats adapted to different levels of inulin. J. Nutr. 121: 1730-1737.
18. Mackie, R. I., Gilchrist, M. C., Robberts, A. M., Hannah, P. E. & Schwartz, H. M. (1978) Microbiological and chemical changes in the rumen during the stepwise adaptation of sheep to high concentrate diets. J. Agric. Sci. (Camb.) 90: 241-254.
19. May, T., Mackie, R. I., Fahey, G. C., Jr., Cremin, J. D. & Garleb, K. A. (1994) Effect of fiber source on short-chain fatty acid production and on the growth and toxin production by Clostridium difficile. Scand. J. Gastroenterol. 19: 916-922.
20. Mitsuoka, T. (1990) Bifidobacteria and their role in human health. J. Indust. Microbiol. 6: 263-268.
21. Mitsuoka, T., Hidaka, H. & Eida, T. (1987) Effect of fructo-oligosaccharides on intestinal microflora. Die Nahrung 31: 427-436.
22. Muñoa, F. J. & Pares, R. (1988) Selective medium for isolation and enumeration of Bifidobacterium spp. Appl. Environ. Microbiol. 54: 1715-1718.
23. National Research Council. (1995) Nutrient Requirements of Laboratory Animals. National Academy Press, Washington, DC.
24. Okazaki, M., Fujikawa, S. & Matsumoto, N. (1990) Effect of xylooligosaccharide on the growth of bifidobacteria. Bifidobact. Microflora 9: 77-86.
25. Rémésy, C., Behr, S. R., Levrat, M. A. & Demigné, C. (1992) Fiber fermentability in the rat cecum and its physiological consequences. Nutr. Res. 12: 1235-1244.
26. Roberfroid, M., Gibson, G. R. & Delzenne, N. (1993) The biochemistry of oligofructose, a nondigestible fiber: an approach to calculate its caloric value. Nutr. Rev. 51: 137-146.
27. Roediger, W.E.W. (1980a) Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut 21: 793-798.
28. Roediger, W.E.W. (1980b) The colonic epithelium in ulcerative colitis: an energy-deficiency disease? Lancet ii: 712-715.
29. SAS Institute Inc. (1992) SAS User's Guide: Statistics, 6.10 ed. SAS Institute, Cary, NC.
30. Williams, C. H., Witherly, S. A. & Buddington, R. K. (1994) Influence of dietary neosugar on selected bacterial groups of the human faecal microbiota. Micro. Ecol. Health Dis. 7: 91-97.
31. Younes, H., Garleb, K., Behr, S., Rémésy, C. & Demigné, C. (1995) Fermentable fibers or oligosaccharides reduce urinary nitrogen excretion by increasing urea disposal in the rat cecum. J. Nutr. 125: 1010-1016.