-
1
-
-
77957329119
-
Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli
-
COI: 1:CAS:528:DC%2BC3cXht1WmtbnO, PID: 20929806
-
Ajikumar PK, Xiao WH, Tyo KEJ, Wang Y, Simeon F, Leonard E, Mucha O, Phon TH, Pfeifer B, Stephanopoulos G (2010) Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli. Science 330:70–74
-
(2010)
Science
, vol.330
, pp. 70-74
-
-
Ajikumar, P.K.1
Xiao, W.H.2
Tyo, K.E.J.3
Wang, Y.4
Simeon, F.5
Leonard, E.6
Mucha, O.7
Phon, T.H.8
Pfeifer, B.9
Stephanopoulos, G.10
-
2
-
-
84900827538
-
Kinetic models in industrial biotechnology: improving cell factory performance
-
COI: 1:CAS:528:DC%2BC2cXhtFansrvM, PID: 24747045
-
Almquist J, Cvijovic M, Hatzimanikatis V, Nielsen J, Jirstrand M (2014) Kinetic models in industrial biotechnology: improving cell factory performance. Metab Eng 24:38–60
-
(2014)
Metab Eng
, vol.24
, pp. 38-60
-
-
Almquist, J.1
Cvijovic, M.2
Hatzimanikatis, V.3
Nielsen, J.4
Jirstrand, M.5
-
3
-
-
84877256074
-
Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols
-
COI: 1:CAS:528:DC%2BC3sXjtlOisLg%3D, PID: 23417095
-
Avalos JL, Fink GR, Stephanopoulos G (2013) Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols. Nat Biotechnol 31:335–341
-
(2013)
Nat Biotechnol
, vol.31
, pp. 335-341
-
-
Avalos, J.L.1
Fink, G.R.2
Stephanopoulos, G.3
-
4
-
-
34347258175
-
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox
-
COI: 1:CAS:528:DC%2BD2sXhtFGntbfI, PID: 17406635
-
Becker SA, Feist AM, Mo ML, Hannum G, Palsson BØ, Herrgard MJ (2007) Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox. Nat Protoc 2:727–738
-
(2007)
Nat Protoc
, vol.2
, pp. 727-738
-
-
Becker, S.A.1
Feist, A.M.2
Mo, M.L.3
Hannum, G.4
Palsson, B.Ø.5
Herrgard, M.J.6
-
5
-
-
84902154110
-
Multivariate modular metabolic engineering for pathway and strain optimization
-
COI: 1:CAS:528:DC%2BC2cXhtlSqu7vM, PID: 24927371
-
Biggs BW, De Paepe B, Santos CNS, De Mey M, Kumaran Ajikumar P (2014) Multivariate modular metabolic engineering for pathway and strain optimization. Curr Opin Biotechnol 29:156–162
-
(2014)
Curr Opin Biotechnol
, vol.29
, pp. 156-162
-
-
Biggs, B.W.1
De Paepe, B.2
Santos, C.N.S.3
De Mey, M.4
Kumaran Ajikumar, P.5
-
6
-
-
84879292930
-
Targeting enzymes to the right compartment: Metabolic engineering for itaconic acid production by Aspergillus niger
-
COI: 1:CAS:528:DC%2BC3sXhsVWqsLnO, PID: 23727192
-
Blumhoff ML, Steiger MG, Mattanovich D, Sauer M (2013) Targeting enzymes to the right compartment: Metabolic engineering for itaconic acid production by Aspergillus niger. Metab Eng 19:26–32
-
(2013)
Metab Eng
, vol.19
, pp. 26-32
-
-
Blumhoff, M.L.1
Steiger, M.G.2
Mattanovich, D.3
Sauer, M.4
-
7
-
-
79955065138
-
Optimization of a blueprint for in vitro glycolysis by metabolic real-time analysis
-
COI: 1:CAS:528:DC%2BC3MXjsVKqtLk%3D, PID: 21423171
-
Bujara M, Schümperli M, Pellaux R, Heinemann M, Panke S (2011) Optimization of a blueprint for in vitro glycolysis by metabolic real-time analysis. Nat Chem Biol 7:271–277
-
(2011)
Nat Chem Biol
, vol.7
, pp. 271-277
-
-
Bujara, M.1
Schümperli, M.2
Pellaux, R.3
Heinemann, M.4
Panke, S.5
-
8
-
-
84899079198
-
A brief history of synthetic biology
-
COI: 1:CAS:528:DC%2BC2cXlt1eqsro%3D, PID: 24686414
-
Cameron DE, Bashor CJ, Collins JJ (2014) A brief history of synthetic biology. Nat Rev Microbiol 12:381–390
-
(2014)
Nat Rev Microbiol
, vol.12
, pp. 381-390
-
-
Cameron, D.E.1
Bashor, C.J.2
Collins, J.J.3
-
9
-
-
84907350970
-
Generation of an atlas for commodity chemical production in Escherichia coli and a novel pathway prediction algorithm
-
COI: 1:CAS:528:DC%2BC2cXht1OqsLvL
-
Campodonico MA, Andrews BA, Asenjo JA, Palsson BO, Feist AM (2014) Generation of an atlas for commodity chemical production in Escherichia coli and a novel pathway prediction algorithm. GEM-Path Metab Eng 25:140–158
-
(2014)
GEM-Path Metab Eng
, vol.25
, pp. 140-158
-
-
Campodonico, M.A.1
Andrews, B.A.2
Asenjo, J.A.3
Palsson, B.O.4
Feist, A.M.5
-
10
-
-
84887618970
-
Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks
-
COI: 1:CAS:528:DC%2BC3sXltVektLw%3D, PID: 23541505
-
Chen Y, Nielsen J (2013) Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks. Curr Opin Biotechnol 24:965–972
-
(2013)
Curr Opin Biotechnol
, vol.24
, pp. 965-972
-
-
Chen, Y.1
Nielsen, J.2
-
11
-
-
84877127500
-
Protein design in systems metabolic engineering for industrial strain development
-
PID: 23589416
-
Chen Z, Zeng AP (2013) Protein design in systems metabolic engineering for industrial strain development. Biotechnol J 8:523–533
-
(2013)
Biotechnol J
, vol.8
, pp. 523-533
-
-
Chen, Z.1
Zeng, A.P.2
-
12
-
-
84879392986
-
Metabolic engineering of Torulopsis glabrata for malate production
-
COI: 1:CAS:528:DC%2BC3sXhsVWqs7nM, PID: 23707987
-
Chen X, Xu G, Xu N, Zou W, Zhu P, Liu L, Chen J (2013) Metabolic engineering of Torulopsis glabrata for malate production. Metab Eng 19:10–16
-
(2013)
Metab Eng
, vol.19
, pp. 10-16
-
-
Chen, X.1
Xu, G.2
Xu, N.3
Zou, W.4
Zhu, P.5
Liu, L.6
Chen, J.7
-
13
-
-
84863229940
-
DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency
-
COI: 1:CAS:528:DC%2BC38XjtlGksrY%3D, PID: 22021385
-
Conrado RJ, Wu GC, Boock JT, Xu H, Chen SY, Lebar T, Turnšek J, Tomšič N, Avbelj M, Koprivnjak T (2012) DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. Nucleic Acids Res 40:1879–1889
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 1879-1889
-
-
Conrado, R.J.1
Wu, G.C.2
Boock, J.T.3
Xu, H.4
Chen, S.Y.5
Lebar, T.6
Turnšek, J.7
Tomšič, N.8
Avbelj, M.9
Koprivnjak, T.10
-
14
-
-
84896142083
-
One step DNA assembly for combinatorial metabolic engineering
-
COI: 1:CAS:528:DC%2BC2cXntFGhsbc%3D, PID: 24594279
-
Coussement P, Maertens J, Beauprez J, Van Bellegem W, De Mey M (2014) One step DNA assembly for combinatorial metabolic engineering. Metab Eng 23:70–77
-
(2014)
Metab Eng
, vol.23
, pp. 70-77
-
-
Coussement, P.1
Maertens, J.2
Beauprez, J.3
Van Bellegem, W.4
De Mey, M.5
-
15
-
-
84870027847
-
Designing and using RNA scaffolds to assemble proteins in vivo
-
COI: 1:CAS:528:DC%2BC38XhtlWgurvL, PID: 22955695
-
Delebecque CJ, Silver PA, Lindner AB (2012) Designing and using RNA scaffolds to assemble proteins in vivo. Nat Protoc 7(10):1797–1807
-
(2012)
Nat Protoc
, vol.7
, Issue.10
, pp. 1797-1807
-
-
Delebecque, C.J.1
Silver, P.A.2
Lindner, A.B.3
-
16
-
-
68449088806
-
Synthetic protein scaffolds provide modular control over metabolic flux
-
COI: 1:CAS:528:DC%2BD1MXpt1Ogsrs%3D, PID: 19648908
-
Dueber JE, Wu GC, Malmirchegini GR, Moon TS, Petzold CJ, Ullal AV, Prather KLJ, Keasling JD (2009) Synthetic protein scaffolds provide modular control over metabolic flux. Nat Biotechnol 27:753–759
-
(2009)
Nat Biotechnol
, vol.27
, pp. 753-759
-
-
Dueber, J.E.1
Wu, G.C.2
Malmirchegini, G.R.3
Moon, T.S.4
Petzold, C.J.5
Ullal, A.V.6
Prather, K.L.J.7
Keasling, J.D.8
-
17
-
-
84899930255
-
Stepwise metabolic engineering of Gluconobacter oxydans WSH-003 for the direct production of 2-keto-l-gulonic acid from D-sorbitol
-
COI: 1:CAS:528:DC%2BC2cXhtFansrrM, PID: 24792618
-
Gao L, Hu Y, Liu J, Du G, Zhou J, Chen J (2014) Stepwise metabolic engineering of Gluconobacter oxydans WSH-003 for the direct production of 2-keto-l-gulonic acid from D-sorbitol. Metab Eng 24:30–37
-
(2014)
Metab Eng
, vol.24
, pp. 30-37
-
-
Gao, L.1
Hu, Y.2
Liu, J.3
Du, G.4
Zhou, J.5
Chen, J.6
-
18
-
-
79960964285
-
Regulation and control of metabolic fluxes in microbes
-
COI: 1:CAS:528:DC%2BC3MXpvFSmtb4%3D, PID: 21600757
-
Gerosa L, Sauer U (2011) Regulation and control of metabolic fluxes in microbes. Curr Opin Biotechnol 22:566–575
-
(2011)
Curr Opin Biotechnol
, vol.22
, pp. 566-575
-
-
Gerosa, L.1
Sauer, U.2
-
19
-
-
67349270900
-
Enzymatic assembly of DNA molecules up to several hundred kilobases
-
COI: 1:CAS:528:DC%2BD1MXksVemsbw%3D, PID: 19363495
-
Gibson DG, Young L, Chuang R-Y, Venter JC, Hutchison CA, Smith HO (2009) Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat Methods 6:343–345
-
(2009)
Nat Methods
, vol.6
, pp. 343-345
-
-
Gibson, D.G.1
Young, L.2
Chuang, R.-Y.3
Venter, J.C.4
Hutchison, C.A.5
Smith, H.O.6
-
20
-
-
77952883945
-
Systems biology of microbial metabolism
-
COI: 1:CAS:528:DC%2BC3cXntVSlu78%3D
-
Heinemann M, Sauer U (2010) Systems biology of microbial metabolism. Curr Opin Biotechnol 13:337–343
-
(2010)
Curr Opin Biotechnol
, vol.13
, pp. 337-343
-
-
Heinemann, M.1
Sauer, U.2
-
21
-
-
84875766148
-
Glutathione enhances 2-keto-l-gulonic acid production based on Ketogulonicigenium vulgare model iWZ663
-
COI: 1:CAS:528:DC%2BC3sXls1egtr4%3D, PID: 23376843
-
Huang Z, Zou W, Liu J, Liu L (2013) Glutathione enhances 2-keto-l-gulonic acid production based on Ketogulonicigenium vulgare model iWZ663. J Biotechnol 164:454–460
-
(2013)
J Biotechnol
, vol.164
, pp. 454-460
-
-
Huang, Z.1
Zou, W.2
Liu, J.3
Liu, L.4
-
22
-
-
84906784381
-
Constraint-based modeling of heterologous pathways: application and experimental demonstration for overproduction of fatty acids in Escherichia coli
-
COI: 1:CAS:528:DC%2BC2cXpvVarsrw%3D, PID: 24838438
-
Ip K, Donoghue N, Kim MK, Lun DS (2014) Constraint-based modeling of heterologous pathways: application and experimental demonstration for overproduction of fatty acids in Escherichia coli. Biotechnol Bioeng 111:2056–2066
-
(2014)
Biotechnol Bioeng
, vol.111
, pp. 2056-2066
-
-
Ip, K.1
Donoghue, N.2
Kim, M.K.3
Lun, D.S.4
-
23
-
-
84855694523
-
Modular engineering of L-tyrosine production in Escherichia coli
-
COI: 1:CAS:528:DC%2BC38XjsVKkuro%3D, PID: 22020510
-
Juminaga D, Baidoo EE, Redding-Johanson AM, Batth TS, Burd H, Mukhopadhyay A, Petzold CJ, Keasling JD (2012) Modular engineering of L-tyrosine production in Escherichia coli. Appl Environ Microbiol 78:89–98
-
(2012)
Appl Environ Microbiol
, vol.78
, pp. 89-98
-
-
Juminaga, D.1
Baidoo, E.E.2
Redding-Johanson, A.M.3
Batth, T.S.4
Burd, H.5
Mukhopadhyay, A.6
Petzold, C.J.7
Keasling, J.D.8
-
24
-
-
84861440312
-
Systems metabolic engineering of microorganisms for natural and non-natural chemicals
-
COI: 1:CAS:528:DC%2BC38XntF2nt70%3D, PID: 22596205
-
Lee JW, Na D, Park JM, Lee J, Choi S, Lee SY (2012) Systems metabolic engineering of microorganisms for natural and non-natural chemicals. Nat Chem Biol 8:536–546
-
(2012)
Nat Chem Biol
, vol.8
, pp. 536-546
-
-
Lee, J.W.1
Na, D.2
Park, J.M.3
Lee, J.4
Choi, S.5
Lee, S.Y.6
-
25
-
-
84904296838
-
Ensemble modeling for robustness analysis in engineering non-native metabolic pathways
-
COI: 1:CAS:528:DC%2BC2cXht1OrurzF, PID: 24972370
-
Lee Y, Lafontaine Rivera JG, Liao JC (2014) Ensemble modeling for robustness analysis in engineering non-native metabolic pathways. Metab Eng 25:63–71
-
(2014)
Metab Eng
, vol.25
, pp. 63-71
-
-
Lee, Y.1
Lafontaine Rivera, J.G.2
Liao, J.C.3
-
26
-
-
77956371200
-
Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control
-
COI: 1:CAS:528:DC%2BC3cXhtVWmtrnM, PID: 20643967
-
Leonard E, Ajikumar PK, Thayer K, Xiao W-H, Mo JD, Tidor B, Stephanopoulos G, Prather KL (2010) Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control. Proc Natl Acad Sci U S A 107:13654–13659
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 13654-13659
-
-
Leonard, E.1
Ajikumar, P.K.2
Thayer, K.3
Xiao, W.-H.4
Mo, J.D.5
Tidor, B.6
Stephanopoulos, G.7
Prather, K.L.8
-
27
-
-
84899647146
-
Enhancement of acetoin production in Candida glabrata by in silico-aided metabolic engineering
-
PID: 24725668
-
Li S, Gao X, Xu N, Liu L, Chen J (2014a) Enhancement of acetoin production in Candida glabrata by in silico-aided metabolic engineering. Microb Cell Fact 13:55
-
(2014)
Microb Cell Fact
, vol.13
, pp. 55
-
-
Li, S.1
Gao, X.2
Xu, N.3
Liu, L.4
Chen, J.5
-
28
-
-
84892451287
-
Engineering of carboligase activity reaction in Candida glabrata for acetoin production
-
COI: 1:CAS:528:DC%2BC2cXjslOrtLk%3D, PID: 24365210
-
Li S, Xu N, Liu L, Chen J (2014b) Engineering of carboligase activity reaction in Candida glabrata for acetoin production. Metab Eng 22:32–39
-
(2014)
Metab Eng
, vol.22
, pp. 32-39
-
-
Li, S.1
Xu, N.2
Liu, L.3
Chen, J.4
-
29
-
-
84894054579
-
Advancing metabolic models with kinetic information
-
COI: 1:CAS:528:DC%2BC2cXhtlSqu73P, PID: 24534671
-
Link H, Christodoulou D, Sauer U (2014) Advancing metabolic models with kinetic information. Curr Opin Biotechnol 29:8–14
-
(2014)
Curr Opin Biotechnol
, vol.29
, pp. 8-14
-
-
Link, H.1
Christodoulou, D.2
Sauer, U.3
-
30
-
-
84883381736
-
Pathway engineering of Bacillus subtilis for microbial production of N-acetylglucosamine
-
PID: 23876412
-
Liu Y, Liu L, H-d S, Chen RR, Li J, Du G, Chen J (2013) Pathway engineering of Bacillus subtilis for microbial production of N-acetylglucosamine. Metab Eng 19:107–115
-
(2013)
Metab Eng
, vol.19
, pp. 107-115
-
-
Liu, Y.1
Liu, L.2
H-d, S.3
Chen, R.R.4
Li, J.5
Du, G.6
Chen, J.7
-
31
-
-
84896871113
-
Modular pathway engineering of Bacillus subtilis for improved N-acetylglucosamine production
-
COI: 1:CAS:528:DC%2BC2cXntFGhsLc%3D, PID: 24560814
-
Liu Y, Zhu Y, Li J, H-d S, Chen RR, Du G, Liu L, Chen J (2014a) Modular pathway engineering of Bacillus subtilis for improved N-acetylglucosamine production. Metab Eng 23:42–52
-
(2014)
Metab Eng
, vol.23
, pp. 42-52
-
-
Liu, Y.1
Zhu, Y.2
Li, J.3
H-d, S.4
Chen, R.R.5
Du, G.6
Liu, L.7
Chen, J.8
-
32
-
-
84901202594
-
Spatial modulation of key pathway enzymes by DNA-guided scaffold system and respiration chain engineering for improved N-acetylglucosamine production by Bacillus subtilis
-
COI: 1:CAS:528:DC%2BC2cXhtFansrrN, PID: 24815549
-
Liu Y, Zhu Y, Ma W, H-d S, Li J, Liu L, Du G, Chen J (2014b) Spatial modulation of key pathway enzymes by DNA-guided scaffold system and respiration chain engineering for improved N-acetylglucosamine production by Bacillus subtilis. Metab Eng 24:61–69
-
(2014)
Metab Eng
, vol.24
, pp. 61-69
-
-
Liu, Y.1
Zhu, Y.2
Ma, W.3
H-d, S.4
Li, J.5
Liu, L.6
Du, G.7
Chen, J.8
-
33
-
-
84879002382
-
Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli
-
McCloskey D, Palsson BØ, Feist AM (2013) Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli. Mol. Syst. Biol. 9(1)
-
(2013)
Mol. Syst. Biol
, vol.9
, Issue.1
-
-
McCloskey, D.1
Palsson, B.Ø.2
Feist, A.M.3
-
34
-
-
84901300506
-
In vitro metabolic engineering of hydrogen production at theoretical yield from sucrose
-
COI: 1:CAS:528:DC%2BC2cXhtFansr3K, PID: 24836702
-
Myung S, Rollin J, You C, Sun F, Chandrayan S, Adams MW, Zhang Y-HP (2014) In vitro metabolic engineering of hydrogen production at theoretical yield from sucrose. Metab Eng 24:70–77
-
(2014)
Metab Eng
, vol.24
, pp. 70-77
-
-
Myung, S.1
Rollin, J.2
You, C.3
Sun, F.4
Chandrayan, S.5
Adams, M.W.6
Zhang, Y.-H.P.7
-
35
-
-
84873596341
-
Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs
-
Na D, Yoo SM, Chung H, Park H, Park JH, Lee SY (2013) Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs. Nat Biotechnol 31:170–174
-
(2013)
Nat Biotechnol
, vol.31
, pp. 170-174
-
-
Na, D.1
Yoo, S.M.2
Chung, H.3
Park, H.4
Park, J.H.5
Lee, S.Y.6
-
36
-
-
84901621407
-
Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production
-
COI: 1:CAS:528:DC%2BC2cXhtFansrvK, PID: 24853352
-
Nocon J, Steiger MG, Pfeffer M, Sohn SB, Kim TY, Maurer M, Rußmayer H, Pflügl S, Ask M, Haberhauer-Troyer C (2014) Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production. Metab Eng 24:129–138
-
(2014)
Metab Eng
, vol.24
, pp. 129-138
-
-
Nocon, J.1
Steiger, M.G.2
Pfeffer, M.3
Sohn, S.B.4
Kim, T.Y.5
Maurer, M.6
Rußmayer, H.7
Pflügl, S.8
Ask, M.9
Haberhauer-Troyer, C.10
-
37
-
-
84899051891
-
Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development
-
COI: 1:CAS:528:DC%2BC2cXlt1Cmu78%3D, PID: 24686413
-
Paddon CJ, Keasling JD (2014) Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development. Nat Rev Microbiol 12:355–367
-
(2014)
Nat Rev Microbiol
, vol.12
, pp. 355-367
-
-
Paddon, C.J.1
Keasling, J.D.2
-
38
-
-
84900314611
-
CRISPR-Cas systems for editing, regulating and targeting genomes
-
COI: 1:CAS:528:DC%2BC2cXjtlyrsLo%3D, PID: 24584096
-
Sander JD, Joung JK (2014) CRISPR-Cas systems for editing, regulating and targeting genomes. Nat Biotechnol 32:347–355
-
(2014)
Nat Biotechnol
, vol.32
, pp. 347-355
-
-
Sander, J.D.1
Joung, J.K.2
-
39
-
-
84899628032
-
Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch
-
COI: 1:CAS:528:DC%2BC2cXltFCjsro%3D, PID: 24576819
-
Soma Y, Tsuruno K, Wada M, Yokota A, Hanai T (2014) Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch. Metab Eng 23:175–184
-
(2014)
Metab Eng
, vol.23
, pp. 175-184
-
-
Soma, Y.1
Tsuruno, K.2
Wada, M.3
Yokota, A.4
Hanai, T.5
-
40
-
-
84869420041
-
Synthetic biology and metabolic engineering
-
COI: 1:CAS:528:DC%2BC38XhsF2qtrjP, PID: 23656228
-
Stephanopoulos G (2012) Synthetic biology and metabolic engineering. ACS Synth Biol 1(11):514–525
-
(2012)
ACS Synth Biol
, vol.1
, Issue.11
, pp. 514-525
-
-
Stephanopoulos, G.1
-
41
-
-
68449103617
-
Stabilized gene duplication enables long-term selection-free heterologous pathway expression
-
COI: 1:CAS:528:DC%2BD1MXovFymtb8%3D, PID: 19633654
-
Tyo KEJ, Ajikumar PK, Stephanopoulos G (2009) Stabilized gene duplication enables long-term selection-free heterologous pathway expression. Nat Biotechnol 27(8):760–765
-
(2009)
Nat Biotechnol
, vol.27
, Issue.8
, pp. 760-765
-
-
Tyo, K.E.J.1
Ajikumar, P.K.2
Stephanopoulos, G.3
-
42
-
-
84855229099
-
Synthetic scaffolds increased resveratrol biosynthesis in engineered yeast cells
-
COI: 1:CAS:528:DC%2BC38XhvVGitA%3D%3D, PID: 22100267
-
Wang Y, Yu O (2012) Synthetic scaffolds increased resveratrol biosynthesis in engineered yeast cells. J Biotechnol 157:258–260
-
(2012)
J Biotechnol
, vol.157
, pp. 258-260
-
-
Wang, Y.1
Yu, O.2
-
43
-
-
84911430915
-
A kinetic-based approach to understanding heterologous mevalonate pathway function in E. coli
-
PID: 24981116
-
Weaver LJ, Sousa MM, Wang G, Baidoo E, Petzold CJ, Keasling JD (2014) A kinetic-based approach to understanding heterologous mevalonate pathway function in E. coli. Biotechnol Bioeng. doi:10.1002/bit.25323
-
(2014)
Biotechnol Bioeng
-
-
Weaver, L.J.1
Sousa, M.M.2
Wang, G.3
Baidoo, E.4
Petzold, C.J.5
Keasling, J.D.6
-
44
-
-
84872221971
-
Metabolic engineering of Escherichia coli for (2S)-pinocembrin production from glucose by a modular metabolic strategy
-
PID: 23246524
-
Wu J, Du G, Zhou J, Chen J (2013a) Metabolic engineering of Escherichia coli for (2S)-pinocembrin production from glucose by a modular metabolic strategy. Metab Eng 16:48–55
-
(2013)
Metab Eng
, vol.16
, pp. 48-55
-
-
Wu, J.1
Du, G.2
Zhou, J.3
Chen, J.4
-
45
-
-
84883232076
-
Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from l-tyrosine
-
COI: 1:CAS:528:DC%2BC3sXhsVOksbzP, PID: 23916948
-
Wu J, Liu P, Fan Y, Bao H, Du G, Zhou J, Chen J (2013b) Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from l-tyrosine. J Biotechnol 167:404–411
-
(2013)
J Biotechnol
, vol.167
, pp. 404-411
-
-
Wu, J.1
Liu, P.2
Fan, Y.3
Bao, H.4
Du, G.5
Zhou, J.6
Chen, J.7
-
46
-
-
84871550797
-
Fumaric acid production in Saccharomyces cerevisiae by in silico aided metabolic engineering
-
COI: 1:CAS:528:DC%2BC3sXmtVWhtg%3D%3D, PID: 23300594
-
Xu G, Zou W, Chen X, Xu N, Liu L, Chen J (2012) Fumaric acid production in Saccharomyces cerevisiae by in silico aided metabolic engineering. PLoS One 7:e52086
-
(2012)
PLoS One
, vol.7
, pp. e52086
-
-
Xu, G.1
Zou, W.2
Chen, X.3
Xu, N.4
Liu, L.5
Chen, J.6
-
47
-
-
84873997973
-
Genome-scale metabolic model in guiding metabolic engineering of microbial improvement
-
COI: 1:CAS:528:DC%2BC3sXosFShug%3D%3D, PID: 23188456
-
Xu C, Liu L, Zhang Z, Jin D, Qiu J, Chen M (2013a) Genome-scale metabolic model in guiding metabolic engineering of microbial improvement. Appl Microbiol Biotechnol 97:519–539
-
(2013)
Appl Microbiol Biotechnol
, vol.97
, pp. 519-539
-
-
Xu, C.1
Liu, L.2
Zhang, Z.3
Jin, D.4
Qiu, J.5
Chen, M.6
-
48
-
-
84872070745
-
Reconstruction and analysis of the genome-scale metabolic network of Candida glabrata
-
COI: 1:CAS:528:DC%2BC3sXhsFSnsA%3D%3D, PID: 23172360
-
Xu N, Liu L, Zou W, Liu J, Hua Q, Chen J (2013b) Reconstruction and analysis of the genome-scale metabolic network of Candida glabrata. Mol Biosyst 9:205–216
-
(2013)
Mol Biosyst
, vol.9
, pp. 205-216
-
-
Xu, N.1
Liu, L.2
Zou, W.3
Liu, J.4
Hua, Q.5
Chen, J.6
-
49
-
-
84877804801
-
Modular optimization of multi-gene pathways for fatty acids production in E. coli
-
PID: 23361000
-
Xu P, Gu Q, Wang W, Wong L, Bower AG, Collins CH, Koffas MA (2013c) Modular optimization of multi-gene pathways for fatty acids production in E. coli. Nat Commun 4:1409
-
(2013)
Nat Commun
, vol.4
, pp. 1409
-
-
Xu, P.1
Gu, Q.2
Wang, W.3
Wong, L.4
Bower, A.G.5
Collins, C.H.6
Koffas, M.A.7
-
50
-
-
84905668376
-
Improving fatty acids production by engineering dynamic pathway regulation and metabolic control
-
COI: 1:CAS:528:DC%2BC2cXhtFyqtL3F, PID: 25049420
-
Xu P, Li L, Zhang F, Stephanopoulos G, Koffas M (2014) Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. Proc Natl Acad Sci U S A 111:11299–11304
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 11299-11304
-
-
Xu, P.1
Li, L.2
Zhang, F.3
Stephanopoulos, G.4
Koffas, M.5
-
51
-
-
84883802093
-
Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica
-
COI: 1:CAS:528:DC%2BC3sXhtFCisr7L, PID: 23873085
-
Xue Z, Sharpe PL, Hong S-P, Yadav NS, Xie D, Short DR, Damude HG, Rupert RA, Seip JE, Wang J (2013) Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica. Nat Biotechnol 31(8):734–740
-
(2013)
Nat Biotechnol
, vol.31
, Issue.8
, pp. 734-740
-
-
Xue, Z.1
Sharpe, P.L.2
Hong, S.-P.3
Yadav, N.S.4
Xie, D.5
Short, D.R.6
Damude, H.G.7
Rupert, R.A.8
Seip, J.E.9
Wang, J.10
-
52
-
-
79959374585
-
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol
-
COI: 1:CAS:528:DC%2BC3MXmsVGlsLw%3D, PID: 21602812
-
Yim H, Haselbeck R, Niu W, Pujol-Baxley C, Burgard A, Boldt J, Khandurina J, Trawick JD, Osterhout RE, Stephen R (2011) Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol. Nat Chem Biol 7:445–452
-
(2011)
Nat Chem Biol
, vol.7
, pp. 445-452
-
-
Yim, H.1
Haselbeck, R.2
Niu, W.3
Pujol-Baxley, C.4
Burgard, A.5
Boldt, J.6
Khandurina, J.7
Trawick, J.D.8
Osterhout, R.E.9
Stephen, R.10
-
53
-
-
81755185882
-
In vitro reconstitution and steady-state analysis of the fatty acid synthase from Escherichia coli
-
COI: 1:CAS:528:DC%2BC3MXhs1WjtL7E, PID: 22042840
-
Yu X, Liu T, Zhu F, Khosla C (2011) In vitro reconstitution and steady-state analysis of the fatty acid synthase from Escherichia coli. Proc Natl Acad Sci U S A 108:18643–18648
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 18643-18648
-
-
Yu, X.1
Liu, T.2
Zhu, F.3
Khosla, C.4
-
54
-
-
84877292750
-
Spanning high-dimensional expression space using ribosome-binding site combinatorics
-
COI: 1:CAS:528:DC%2BC3sXntVyjs7o%3D, PID: 23470993
-
Zelcbuch L, Antonovsky N, Bar-Even A, Levin-Karp A, Barenholz U, Dayagi M, Liebermeister W, Flamholz A, Noor E, Amram S (2013) Spanning high-dimensional expression space using ribosome-binding site combinatorics. Nucleic Acids Res 41:e98
-
(2013)
Nucleic Acids Res
, vol.41
, pp. e98
-
-
Zelcbuch, L.1
Antonovsky, N.2
Bar-Even, A.3
Levin-Karp, A.4
Barenholz, U.5
Dayagi, M.6
Liebermeister, W.7
Flamholz, A.8
Noor, E.9
Amram, S.10
-
55
-
-
84865600352
-
Metabolic engineering of Escherichia coli BL21 for biosynthesis of heparosan, a bioengineered heparin precursor
-
COI: 1:CAS:528:DC%2BC38XhtFGitrfM, PID: 22781283
-
Zhang C, Liu L, Teng L, Chen J, Liu J, Li J, Du G, Chen J (2012) Metabolic engineering of Escherichia coli BL21 for biosynthesis of heparosan, a bioengineered heparin precursor. Metab Eng 14:521–527
-
(2012)
Metab Eng
, vol.14
, pp. 521-527
-
-
Zhang, C.1
Liu, L.2
Teng, L.3
Chen, J.4
Liu, J.5
Li, J.6
Du, G.7
Chen, J.8
-
56
-
-
84901617508
-
In vitro reconstitution of mevalonate pathway and targeted engineering of farnesene overproduction in Escherichia coli
-
COI: 1:CAS:528:DC%2BC2cXisFOgtb0%3D, PID: 24473754
-
Zhu F, Zhong X, Hu M, Lu L, Deng Z, Liu T (2014) In vitro reconstitution of mevalonate pathway and targeted engineering of farnesene overproduction in Escherichia coli. Biotechnol Bioeng 111(7):1396–1405
-
(2014)
Biotechnol Bioeng
, vol.111
, Issue.7
, pp. 1396-1405
-
-
Zhu, F.1
Zhong, X.2
Hu, M.3
Lu, L.4
Deng, Z.5
Liu, T.6
-
57
-
-
84863474170
-
Reconstruction and analysis of a genome-scale metabolic model of the vitamin C producing industrial strain Ketogulonicigenium vulgare WSH-001
-
COI: 1:CAS:528:DC%2BC38XhtVymt73N, PID: 22728423
-
Zou W, Liu L, Zhang J, Yang H, Zhou M, Hua Q, Chen J (2012) Reconstruction and analysis of a genome-scale metabolic model of the vitamin C producing industrial strain Ketogulonicigenium vulgare WSH-001. J Biotechnol 161:42–48
-
(2012)
J Biotechnol
, vol.161
, pp. 42-48
-
-
Zou, W.1
Liu, L.2
Zhang, J.3
Yang, H.4
Zhou, M.5
Hua, Q.6
Chen, J.7
-
58
-
-
84875797806
-
Reconstruction and analysis of the industrial strain Bacillus megaterium WSH002 genome-scale in silico metabolic model
-
COI: 1:CAS:528:DC%2BC3sXls1Cjur8%3D, PID: 23454894
-
Zou W, Zhou M, Liu L, Chen J (2013) Reconstruction and analysis of the industrial strain Bacillus megaterium WSH002 genome-scale in silico metabolic model. J Biotechnol 164:503–509
-
(2013)
J Biotechnol
, vol.164
, pp. 503-509
-
-
Zou, W.1
Zhou, M.2
Liu, L.3
Chen, J.4
|