Pathway engineering of Bacillus subtilis for microbial production of N-acetylglucosamine

Metabolic Engineering

Volumn 19, Issue , 2013, Pages 107-115

  Liu, Yanfeng ^a   Liu, Long ^a   Shin, Hyun dong ^b   Chen, Rachel R ^b   Li, Jianghua ^a   Du, Guocheng ^a   Chen, Jian ^a  

^a JIANGNAN UNIVERSITY   (China)

^b Georgia Institute of Technology   (United States)

Author keywords

Bacillus subtilis; Glucosamine; N acetylglucosamine; Pathway engineering

Indexed keywords

ACETYLATED DERIVATIVES; BACILLUS SUBTILIS; ENVIRONMENTAL POLLUTIONS; FED-BATCH BIOREACTORS; N-ACETYLGLUCOSAMINE; PATHWAY ENGINEERINGS; PHARMACEUTICAL INDUSTRY; PHOSPHOTRANSFERASE SYSTEM;

BOTTLES; ENZYME ACTIVITY; GLUCOSAMINE; SHELLFISH; YEAST;

ENCODING (SYMBOLS);

ACYLTRANSFERASE; BACTERIAL PROTEIN; DEAMINASE; GAMA PROTEIN; GLMS PROTEIN; GNA1 PROTEIN; N ACETYLGLUCOSAMINE; NAGA PROTEIN; NAGB PROTEIN; NAGP PROTEIN; PHOSPHATE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL STRAIN; BACTERIUM CULTURE; CATABOLISM; CONTROLLED STUDY; GENE DELETION; GENE OVEREXPRESSION; KNOCKOUT GENE; METABOLIC ENGINEERING; NONHUMAN; PLASMID; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

BACILLUS SUBTILIS; GLUCOSAMINE; N-ACETYLGLUCOSAMINE; PATHWAY ENGINEERING;

ACETYLGLUCOSAMINE; BACILLUS SUBTILIS; BACTERIAL PROTEINS; GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE; METABOLIC ENGINEERING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84883381736     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2013.07.002     Document Type: Article

References (25)

1. Badet B., Vermoote P., Haumont P.Y., Lederer F., Le Goffic F. Glucosamine synthetase from Escherichia coli: purification, properties, and glutamine-utilizing site location. Biochemistry 1987, 26:1940-1948.
2. Bertram R., Rigali S., Wood N., Lulko A.T., Kuipers O.P., Titgemeyer F. Regulon of the N-acetylglucosamine utilization regulator NagR in Bacillus subtilis. J. Bacteriol. 2011, 193:3525.
3. Biedendieck R., Yang Y., Deckwer W.D., Malten M., Jahn D. Plasmid system for the intracellular production and purification of affinity-tagged proteins in Bacillus megaterium. Biotechnol. Bioeng. 2007, 96:525-537.
4. Chen J.K., Shen C.R., Liu C.L. N-acetylglucosamine: production and applications. Mar. Drugs 2010, 8:2493-2516.
5. Chen X., Liu L., Li J., Du G., Chen J. Improved glucosamine and N-acetylglucosamine production by an engineered Escherichia coli via step-wise regulation of dissolved oxygen level. Bioresource Technol. 2012, 110:534-538.
6. Collins J.A., Irnov I., Baker S., Winkler W.C. Mechanism of mRNA destabilization by the glmS ribozyme. Gene. Dev. 2007, 21:3356-3368.
7. Deng M.D., Grund A.D., Wassink S.L., Peng S.S., Nielsen K.L., Huckins B.D., Walsh B.L., Burlingame R.P. Directed evolution and characterization of Escherichia coli glucosamine synthase. Biochimie 2006, 88:419-429.
8. Deng M.D., Severson D.K., Grund A.D., Wassink S.L., Burlingame R.P., Berry A., Running J.A., Kunesh C.A., Song L., Jerrell T.A. Metabolic engineering of Escherichia coli for industrial production of glucosamine and N-acetylglucosamine. Metab. Eng. 2005, 7:201-214.
9. Kim L., Mogk A., Schumann W. A xylose-inducible Bacillus subtilis integration vector and its application. Gene 1996, 181:71-76.
10. Kuznetsova E., Proudfoot M., Gonzalez C.F., Brown G., Omelchenko M.V., Borozan I., Carmel L., Wolf Y.I., Mori H., Savchenko A.V. Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family. J. Biol. Chem. 2006, 281:36149-36161.
11. Mio T., Yamada-Okabe T., Arisawa M., Yamada-Okabe H. Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis. J. Biol. Chem. 1999, 274:424-429.
12. Mobley H.L., Doyle R.J., Streips U.N., Langemeier S.O. Transport and incorporation of N-acetyl-d-glucosamine in Bacillus subtilis. J. Bacteriol. 1982, 150:8-15.
13. Nakamura H. Application of glucosamine on human disease-Osteoarthritis. Carbohydr. Polym. 2011, 84:835-839.
14. Papenfort K., Sun Y., Miyakoshi M., Vanderpool C.K., Vogel J. Small RNA-mediated activation of sugar phosphatase mRNA regulates glucose homeostasis. Cell 2013, 153:426-437.
15. Ranganath M. Glucosamine and osteoarthritis: time to quit?. Diabetes-Metab. Res. 2011, 27:233-234.
16. Sambrook J., Russell D.W. Molecular Cloning: A Laboratory Manual 2001, Cold Spring Harbor Laboratory Press, NewYork.
17. Schumann W. Production of recombinant proteins in Bacillus subtilis. Adv. Appl. Microbiol. 2007, 62:137-189.
18. Shi S., Chen T., Zhang Z., Chen X., Zhao X. Transcriptome analysis guided metabolic engineering of Bacillus subtilis for riboflavin production. Metab. Eng. 2009, 11:243-252.
19. Sitanggang A.B., Wu H.-S., Wang S.S., Ho Y.-C. Effect of pellet size and stimulating factor on the glucosamine production using Aspergillus sp BCRC 31742. Bioresource Technol. 2010, 101:3595-3601.
20. Vincent F., Yates D., Garman E., Davies G.J., Brannigan J.A. The three-dimensional structure of the N-acetylglucosamine-6-phosphate deacetylase, NagA, from Bacillus subtilis. J. Biol. Chem. 2004, 279:2809-2816.
21. Winkler W.C., Nahvi A., Roth A., Collins J.A., Breaker R.R. Control of gene expression by a natural metabolite-responsive ribozyme. Nature 2004, 428:281-286.
22. Xue G.P., Johnson J.S., Dalrymple B.P. High osmolarity improves the electro-transformation efficiency of the gram-positive bacteria Bacillus subtilis and Bacillus licheniformis. J. Microbiol. Methods 1999, 34:183-191.
23. Yan X., Yu H.J., Hong Q., Li S.P. Cre/lox system and PCR-based genome engineering in Bacillus subtilis. Appl. Environ. Microb. 2008, 74:5556-5562.
24. Zhang X.Z., Cui Z.L., Hong Q., Li S.P. High-level expression and secretion of methyl parathion hydrolase in Bacillus subtilis WB800. Appl. Environ. Microb 2005, 71:4101-4103.
25. Zhang J., Liu L., Li J., Du G., Chen J. Enhanced glucosamine production by Aspergillus sp. BCRC 31742 based on the time-variant kinetics analysis of dissolved oxygen level. Bioresource Technol. 2012, 111:507-511.