Assessing Human Variability in Kinetics for Exposures to Multiple Environmental Chemicals: A Physiologically Based Pharmacokinetic Modeling Case Study with Dichloromethane, Benzene, Toluene, Ethylbenzene, and m-Xylene

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 78, Issue 7, 2015, Pages 409-431

  Valcke, Mathieu ^a,b   Haddad, Sami ^b  

^a INSTITUT NATIONAL DE SANTÉ PUBLIQUE DU QUÉBEC   (Canada)

^b Institut de Recherche en Santé Publique École de Santé Publique Pavillon 7101   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE; CYTOCHROME P450 2E1; DICHLOROMETHANE; ENVIRONMENTAL CHEMICAL; ETHYLBENZENE; META XYLENE; TOLUENE; 3-XYLENE; BENZENE DERIVATIVE; XYLENE;

ADULT; ARTICLE; BLOOD TOXICITY; BODY HEIGHT; BODY WEIGHT; CHILD; CONCENTRATION (PARAMETERS); ENVIRONMENTAL EXPOSURE; EXPOSURE; HUMAN; LIVER WEIGHT; LONG TERM EXPOSURE; MONTE CARLO METHOD; NEOPLASM; NEUROTOXICITY; NEWBORN; PREGNANT WOMAN; PRIORITY JOURNAL; RISK ASSESSMENT; ADOLESCENT; ADVERSE EFFECTS; AGED; COMPUTER SIMULATION; FEMALE; INFANT; MIDDLE AGED; PREGNANCY; PRESCHOOL CHILD; SENSITIVITY AND SPECIFICITY; THEORETICAL MODEL; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; BENZENE; BENZENE DERIVATIVES; CHILD, PRESCHOOL; COMPUTER SIMULATION; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INHALATION EXPOSURE; METHYLENE CHLORIDE; MIDDLE AGED; MODELS, THEORETICAL; MONTE CARLO METHOD; PREGNANCY; SENSITIVITY AND SPECIFICITY; TOLUENE; XYLENES; YOUNG ADULT;

EID: 84925338470     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287394.2014.971477     Document Type: Article

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