An integrated QSAR-PBPK modelling approach for predicting the inhalation toxicokinetics of mixtures of volatile organic chemicals in the rat

SAR and QSAR in Environmental Research

Volumn 22, Issue 1-2, 2011, Pages 107-128

  Price, K ^a   Krishnan, K ^a  

^a UNIVERSITY OF MONTREAL   (Canada)

Author keywords

Mixtures; Pbpk model; Pharmacokinetics; Qsar pbpk model; Toxicokinetics

Indexed keywords

ANESTHETICS; DICHLOROMETHANE; FORECASTING; GAS CHROMATOGRAPHY; ORGANIC CHEMICALS; PHARMACOKINETICS; RATS; STRUCTURE (COMPOSITION); STYRENE; TOLUENE; VOLATILE ORGANIC COMPOUNDS; XYLENE;

BENZENE- TOLUENES; M-XYLENE; MODELING APPROACH; O-XYLENE; P-XYLENE; PARTITION COEFFICIENT; PBPK MODEL; QSAR-PBPK MODEL; TETRACHLOROETHYLENES; TOXICOKINETICS;

ETHYLBENZENE;

RATTUS;

EID: 79952494531     PISSN: 1062936X     EISSN: 1029046X     Source Type: Journal    
DOI: 10.1080/1062936X.2010.548350     Document Type: Article

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