Assessing interaction thresholds for trichloroethylene in combination with tetrachloroethylene and 1,1,1-trichloroethane using gas uptake studies and PBPK modeling

Archives of Toxicology

Volumn 75, Issue 3, 2001, Pages 134-144

  Dobrev, Ivan D ^a   Andersen, Melvin E ^a   Yang, Raymond S H ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Chemical mixtures; Gas uptake; Metabolic interaction; Methylchloroform; PBPK modeling; Sensitivity analysis; Tetrachloroethylene; Trichloroethylene

Indexed keywords

1,1,1 TRICHLOROETHANE; TETRACHLOROETHYLENE; TRICHLOROETHYLENE;

ARTICLE; CHEMICAL INTERACTION; COMPETITIVE INHIBITION; GAS TRANSPORT; MAXIMUM ALLOWABLE CONCENTRATION; METABOLISM; MODEL; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; POLLUTANT; PRIORITY JOURNAL; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

ADMINISTRATION, INHALATION; ANIMALS; ATMOSPHERE EXPOSURE CHAMBERS; BLOOD GAS ANALYSIS; COMPUTER SIMULATION; DRUG COMBINATIONS; DRUG INTERACTIONS; INHALATION EXPOSURE; MALE; MODELS, BIOLOGICAL; RATS; RATS, INBRED F344; TETRACHLOROETHYLENE; THRESHOLD LIMIT VALUES; TRICHLOROETHANES; TRICHLOROETHYLENE;

EID: 0035031341     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040100216     Document Type: Article

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