Internal exposure of children by simulated acute inhalation of volatile organic compounds: The influence of chemical properties on the child/adult concentration ratio

Basic and Clinical Pharmacology and Toxicology

Volumn 96, Issue 3, 2005, Pages 242-243

  Abraham, Klaus ^a   Mielke, Hans ^a   Huisinga, Wilhelm ^b   Gundert Remy, Ursula ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2E1; STYRENE; VOLATILE ORGANIC COMPOUND;

ADOLESCENT; ADULT; AGE; AIRBORNE PARTICLE; CALCULATION; CHEMICAL ANALYSIS; CHILD; CHILDHOOD DISEASE; COMPUTER PROGRAM; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; HUMAN; INFANT; INHALATION; METABOLIC REGULATION; NEWBORN; PARTITION COEFFICIENT; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RISK ASSESSMENT; SIMULATION;

ADMINISTRATION, INHALATION; ADOLESCENT; ADULT; AGE FACTORS; CHILD; CHILD, PRESCHOOL; HUMANS; INFANT; INFANT, NEWBORN; MODELS, BIOLOGICAL; STYRENE;

EID: 14644403429     PISSN: 17427835     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2005.pto960315.x     Document Type: Conference Paper

References (2)

1. Abraham, K., H. Mielke, W. Huisinga & U. Gundert-Remy: Elevated internal exposure of children in simulated acute inhalation of volatile organic compounds: effects of concentration and duration. Arch. Toxicol. 2005, 79, 63-73.
2. Ramsey, J. C. & M. E. Andersen: A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans. Toxicol. Appl. Pharmacol. 1984, 73, 159-175.