Transcriptomics analysis of interactive effects of benzene, trichloroethylene and methyl mercury within binary and ternary mixtures on the liver and kidney following subchronic exposure in the rat

Toxicology and Applied Pharmacology

Volumn 225, Issue 2, 2007, Pages 171-188

  Hendriksen, Peter J M ^a,b   Freidig, Andreas P ^a   Jonker, Diana ^a   Thissen, Uwe ^a   Bogaards, Jan J P ^a   Mumtaz, Moiz M ^c   Groten, John P ^a   Stierum, Rob H ^a  

^a TNO   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

Author keywords

Benzene; Mercury; Microarrays; Mixtures; Toxicogenomics; Trichloroethylene

Indexed keywords

BENZENE; BIOLOGICAL MARKER; MESSENGER RNA; METHYLMERCURY; TRICHLOROETHYLENE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CCNG1 GENE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; GENE; GENE EXPRESSION PROFILING; GENE INDUCTION; ID2 GENE; LIVER TOXICITY; LONG TERM EXPOSURE; MALE; MDM2 GENE; MICROARRAY ANALYSIS; NEPHROTOXICITY; NFKB1 GENE; NONHUMAN; NR2F6 GENE; RAT; STRESS; TISSUE SPECIFICITY; TNFRSF1A GENE; TOXICOGENETICS; TRANSCRIPTOMICS;

ANIMALS; BENZENE; CELL SURVIVAL; DRUG INTERACTIONS; DRUG SYNERGISM; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; KIDNEY; LIVER; MALE; METHYLMERCURY COMPOUNDS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, INBRED F344; RNA, MESSENGER; TOXICITY TESTS; TRICHLOROETHYLENE;

RATTUS;

EID: 36049024442     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.08.017     Document Type: Article

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