Phosphodiesterase-3B-cAMP pathway of leptin signalling in the hypothalamus is impaired during the development of diet-induced obesity in FVB/N mice

Journal of Neuroendocrinology

Volumn 27, Issue 4, 2015, Pages 293-302

  Sahu, M ^a   Anamthathmakula, P ^a   Sahu, A ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

CAMP; Hypothalamus; Leptin; Leptin resistance; P Akt; PDE3B; SOCS3

Indexed keywords

CYCLIC AMP; LEPTIN; PHOSPHODIESTERASE 3B; PHOSPHODIESTERASE III; PROTEIN KINASE B; UNCLASSIFIED DRUG; ONCOPROTEIN; SOCS3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; CONTROLLED STUDY; DIET INDUCED OBESITY; DISEASE ASSOCIATION; HYPERINSULINEMIA; HYPERLEPTINEMIA; HYPERPHAGIA; HYPOTHALAMUS; IMMUNOCYTOCHEMISTRY; IMPAIRED GLUCOSE TOLERANCE; LIPID DIET; LOW FAT DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; DRUG EFFECTS; EATING; METABOLISM; OBESITY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3; DIET, HIGH-FAT; EATING; HYPOTHALAMUS; LEPTIN; MALE; MICE; OBESITY; ONCOGENE PROTEIN V-AKT; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84924967215     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/jne.12266     Document Type: Article

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