Neuronal suppressor of cytokine signaling-3 deficiency enhances hypothalamic leptin-dependent phosphatidylinositol 3-kinase signaling

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 300, Issue 5, 2011, Pages

  Metlakunta, Anantha S ^a   Sahu, Maitrayee ^a   Yasukawa, Hideo ^b   Dhillon, Sandeep S ^c   Belsham, Denise D ^c   Yoshimura, Akihiko ^d   Sahu, Abhiram ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TORONTO   (Canada)

^d KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Leptin resistance; Phosphorylated signal transducer and activator of transcription 3; Proopiomelanocortin

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 1; JANUS KINASE 2; LEPTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROOPIOMELANOCORTIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; GENE DELETION; HYPOTHALAMUS; MOUSE; NERVE CELL; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ADIPOSITY; ANIMALS; CALORIC RESTRICTION; CELL LINE; EATING; GENOTYPE; HYPOTHALAMUS; INSULIN RECEPTOR SUBSTRATE PROTEINS; JANUS KINASE 2; LEPTIN; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; NEURONS; OBESITY; PHENOTYPE; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PRO-OPIOMELANOCORTIN; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TIME FACTORS; TRANSFECTION; WEIGHT LOSS;

EID: 79955837921     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00794.2010     Document Type: Article

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