Leptin induces insulin-like signaling that antagonizes cAMP elevation by glucagon in hepatocytes

Journal of Biological Chemistry

Volumn 275, Issue 15, 2000, Pages 11348-11354

  Zhao, Allan Z ^a,c   Shinohara, Michi M ^a   Huang, Daming ^a   Shimizu, Masami ^a   Eldar Finkelman, Hagit ^a,d   Krebs, Edwin G ^a   Beavo, Joseph A ^a   Bornfeldt, Karin E ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; GLUCAGON; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; LEPTIN; LEPTIN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; CELL METABOLISM; DRUG ANTAGONISM; ENZYME ACTIVATION; INSULIN LIKE ACTIVITY; LIVER CELL; MALE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; CYCLIC AMP; ENZYME ACTIVATION; GLUCAGON; INSULIN; LEPTIN; LIVER; MALE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE;

ANIMALIA;

EID: 0034646633     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.15.11348     Document Type: Article

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