-
1
-
-
38449108436
-
Anti-TNF antibodies: Lessons from the past, roadmap for the future
-
Shealy DJ, Visvanathan S. Anti-TNF antibodies: lessons from the past, roadmap for the future. Handb Exp Pharmacol 2008;181: 101-29.
-
(2008)
Handb Exp Pharmacol
, vol.181
, pp. 101-129
-
-
Shealy, D.J.1
Visvanathan, S.2
-
2
-
-
33746225592
-
Molecular and cellular basis of rheumatoid joint destruction
-
Karouzakis E, Neidhart M, Gay RE, Gay S. Molecular and cellular basis of rheumatoid joint destruction. Immunol Lett 2006;106: 8-13.
-
(2006)
Immunol Lett
, vol.106
, pp. 8-13
-
-
Karouzakis, E.1
Neidhart, M.2
Gay, R.E.3
Gay, S.4
-
3
-
-
33749023888
-
Mechanisms of disease: The molecular and cellular basis of joint destruction in rheumatoid arthritis
-
Muller-Ladner U, Pap T, Gay RE, Neidhart M, Gay S. Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis. Nat Clin Pract Rheumatol 2005;1: 102-10.
-
(2005)
Nat Clin Pract Rheumatol
, vol.1
, pp. 102-110
-
-
Muller-Ladner, U.1
Pap, T.2
Gay, R.E.3
Neidhart, M.4
Gay, S.5
-
4
-
-
0024598308
-
Anchorage-independent growth of synoviocytes from arthritic and normal joints: Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-β and retinoids
-
Lafyatis R, Remmers EF, Roberts AB, Yocum DE, Sporn MB, Wilder RL. Anchorage-independent growth of synoviocytes from arthritic and normal joints: stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-β and retinoids. J Clin Invest 1989;83:1267-76.
-
(1989)
J Clin Invest
, vol.83
, pp. 1267-1276
-
-
Lafyatis, R.1
Remmers, E.F.2
Roberts, A.B.3
Yocum, D.E.4
Sporn, M.B.5
Wilder, R.L.6
-
6
-
-
1842602667
-
Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: Different profiles in trauma and rheumatoid arthritis
-
Konttinen YT, Ainola M, Valleala H, Ma J, Ida H, Mandelin J, et al. Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis. Ann Rheum Dis 1999;58:691-7.
-
(1999)
Ann Rheum Dis
, vol.58
, pp. 691-697
-
-
Konttinen, Y.T.1
Ainola, M.2
Valleala, H.3
Ma, J.4
Ida, H.5
Mandelin, J.6
-
7
-
-
0031035590
-
Increased expression of integrins on fibroblast-like synoviocytes from rheumatoid arthritis in vitro correlates with enhanced binding to extracellular matrix proteins
-
Rinaldi N, Schwarz-Eywill M, Weis D, Leppelmann-Jansen P, Lukoschek M, Keilholz U, et al. Increased expression of integrins on fibroblast-like synoviocytes from rheumatoid arthritis in vitro correlates with enhanced binding to extracellular matrix proteins. Ann Rheum Dis 1997;56:45-51.
-
(1997)
Ann Rheum Dis
, vol.56
, pp. 45-51
-
-
Rinaldi, N.1
Schwarz-Eywill, M.2
Weis, D.3
Leppelmann-Jansen, P.4
Lukoschek, M.5
Keilholz, U.6
-
8
-
-
0025255530
-
Quantitative analysis of cytokine gene expression in rheumatoid arthritis
-
Firestein GS, Alvaro-Gracia JM, Maki R. Quantitative analysis of cytokine gene expression in rheumatoid arthritis. J Immunol 1990;144:3347-53.
-
(1990)
J Immunol
, vol.144
, pp. 3347-3353
-
-
Firestein, G.S.1
Alvaro-Gracia, J.M.2
Maki, R.3
-
9
-
-
40849139208
-
Epigenetics in cancer [review]
-
Esteller M. Epigenetics in cancer [review]. N Engl J Med 2008; 358:1148-59.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
10
-
-
31544456085
-
The role of mammalian DNA methyltransferases in the regulation of gene expression
-
Turek-Plewa J, Jagodzinski PP. The role of mammalian DNA methyltransferases in the regulation of gene expression. Cell Mol Biol Lett 2005;10:631-47.
-
(2005)
Cell Mol Biol Lett
, vol.10
, pp. 631-647
-
-
Turek-Plewa, J.1
Jagodzinski, P.P.2
-
11
-
-
33645284007
-
Methylation of endogenous human retroelements in health and disease
-
Schulz WA, Steinhoff C, Florl AR. Methylation of endogenous human retroelements in health and disease. Curr Top Microbiol Immunol 2006;310:211-50.
-
(2006)
Curr Top Microbiol Immunol
, vol.310
, pp. 211-250
-
-
Schulz, W.A.1
Steinhoff, C.2
Florl, A.R.3
-
12
-
-
0034541591
-
Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: Association with genomic DNA hypomethylation and influence on gene expression
-
Neidhart M, Rethage J, Kuchen S, Kunzler P, Crowl RM, Billingham ME, et al. Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression. Arthritis Rheum 2000;43:2634-47.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2634-2647
-
-
Neidhart, M.1
Rethage, J.2
Kuchen, S.3
Kunzler, P.4
Crowl, R.M.5
Billingham, M.E.6
-
13
-
-
0038208086
-
Overexpression of transcripts containing LINE-1 in the synovia of patients with rheumatoid arthritis
-
Ali M, Veale DJ, Reece RJ, Quinn M, Henshaw K, Zanders ED, et al. Overexpression of transcripts containing LINE-1 in the synovia of patients with rheumatoid arthritis. Ann Rheum Dis 2003;62:663-6.
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 663-666
-
-
Ali, M.1
Veale, D.J.2
Reece, R.J.3
Quinn, M.4
Henshaw, K.5
Zanders, E.D.6
-
14
-
-
0033404952
-
Methylation-dependent gene silencing induced by interleukin 1β via nitric oxide production
-
Hmadcha A, Bedoya FJ, Sobrino F, Pintado E. Methylation-dependent gene silencing induced by interleukin 1β via nitric oxide production. J Exp Med 1999;190:1595-604.
-
(1999)
J Exp Med
, vol.190
, pp. 1595-1604
-
-
Hmadcha, A.1
Bedoya, F.J.2
Sobrino, F.3
Pintado, E.4
-
15
-
-
33751280992
-
Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression
-
Wehbe H, Henson R, Meng F, Mize-Berge J, Patel T. Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression. Cancer Res 2006;66:10517-24.
-
(2006)
Cancer Res
, vol.66
, pp. 10517-10524
-
-
Wehbe, H.1
Henson, R.2
Meng, F.3
Mize-Berge, J.4
Patel, T.5
-
16
-
-
0035320566
-
The role of DNA methyltransferase 1 in growth control
-
Szyf M. The role of DNA methyltransferase 1 in growth control. Front Biosci 2001;6:D599-609.
-
(2001)
Front Biosci
, vol.6
-
-
Szyf, M.1
-
18
-
-
33644890154
-
Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells
-
Takami N, Osawa K, Miura Y, Komai K, Taniguchi M, Shiraishi M, et al. Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells. Arthritis Rheum 2006;54:779-87.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 779-787
-
-
Takami, N.1
Osawa, K.2
Miura, Y.3
Komai, K.4
Taniguchi, M.5
Shiraishi, M.6
-
19
-
-
14144253706
-
Galectin-3 is induced in rheumatoid arthritis synovial fibroblasts after adhesion to cartilage oligomeric matrix protein
-
Neidhart M, Zaucke F, von Knoch R, Jungel A, Michel BA, Gay RE, et al. Galectin-3 is induced in rheumatoid arthritis synovial fibroblasts after adhesion to cartilage oligomeric matrix protein. Ann Rheum Dis 2005;64:419-24.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 419-424
-
-
Neidhart, M.1
Zaucke, F.2
von Knoch, R.3
Jungel, A.4
Michel, B.A.5
Gay, R.E.6
-
20
-
-
0030612494
-
Interleukin-1β-stimulated invasion of articular cartilage by rheumatoid synovial fibroblasts is inhibited by antibodies to specific integrin receptors and by collagenase inhibitors
-
Wang AZ, Wang JC, Fisher GW, Diamond HS. Interleukin-1β-stimulated invasion of articular cartilage by rheumatoid synovial fibroblasts is inhibited by antibodies to specific integrin receptors and by collagenase inhibitors. Arthritis Rheum 1997;40: 1298-307.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1298-1307
-
-
Wang, A.Z.1
Wang, J.C.2
Fisher, G.W.3
Diamond, H.S.4
-
21
-
-
0031932838
-
Soluble recombinant neutral endopeptidase (CD10) as a potential antiinflammatory agent
-
Solan NJ, Ward PE, Sanders SP, Towns MC, Bathon JM. Soluble recombinant neutral endopeptidase (CD10) as a potential antiinflammatory agent. Inflammation 1998;22:107-21.
-
(1998)
Inflammation
, vol.22
, pp. 107-121
-
-
Solan, N.J.1
Ward, P.E.2
Sanders, S.P.3
Towns, M.C.4
Bathon, J.M.5
-
22
-
-
41449106186
-
Immune cells and mediators of inflammatory arthritis [review]
-
Schett G. Immune cells and mediators of inflammatory arthritis [review]. Autoimmunity 2008;41:224-9.
-
(2008)
Autoimmunity
, vol.41
, pp. 224-229
-
-
Schett, G.1
-
23
-
-
0034775793
-
-
Wahl AF, Wallace PM. Oncostatin M in the anti-inflammatory response. Ann Rheum Dis 2001;60 Suppl 3:iii75-80.
-
Wahl AF, Wallace PM. Oncostatin M in the anti-inflammatory response. Ann Rheum Dis 2001;60 Suppl 3:iii75-80.
-
-
-
-
24
-
-
35648962500
-
Cysteine and serine proteases of synovial tissue in rheumatoid arthritis and osteoarthritis
-
Solau-Gervais E, Zerimech F, Lemaire R, Fontaine C, Huet G, Flipo RM. Cysteine and serine proteases of synovial tissue in rheumatoid arthritis and osteoarthritis. Scand J Rheumatol 2007; 36:373-7.
-
(2007)
Scand J Rheumatol
, vol.36
, pp. 373-377
-
-
Solau-Gervais, E.1
Zerimech, F.2
Lemaire, R.3
Fontaine, C.4
Huet, G.5
Flipo, R.M.6
-
25
-
-
34247591787
-
Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation
-
Masuda K, Masuda R, Neidhart M, Simmens BR, Michel BA, Muller-Ladner U, et al. Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation. Arthritis Res 2002;4:R8.
-
(2002)
Arthritis Res
, vol.4
-
-
Masuda, K.1
Masuda, R.2
Neidhart, M.3
Simmens, B.R.4
Michel, B.A.5
Muller-Ladner, U.6
-
26
-
-
22244472310
-
Retroviral gene transfer of an antisense construct against membrane type 1 matrix metalloproteinase reduces the invasiveness of rheumatoid arthritis synovial fibroblasts
-
Rutkauskaite E, Volkmer D, Shigeyama Y, Schedel J, Pap G, Muller-Ladner U, et al. Retroviral gene transfer of an antisense construct against membrane type 1 matrix metalloproteinase reduces the invasiveness of rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 2005;52:2010-4.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2010-2014
-
-
Rutkauskaite, E.1
Volkmer, D.2
Shigeyama, Y.3
Schedel, J.4
Pap, G.5
Muller-Ladner, U.6
-
27
-
-
0037453906
-
Effects of 5-aza-2′- deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness
-
Sato N, Maehara N, Su GH, Goggins M. Effects of 5-aza-2′- deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness. J Natl Cancer Inst 2003;95:327-30.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 327-330
-
-
Sato, N.1
Maehara, N.2
Su, G.H.3
Goggins, M.4
-
28
-
-
20444464890
-
Transforming growth factor β stimulates rheumatoid synovial fibroblasts via the type II receptor
-
Bira Y, Tani K, Nishioka Y, Miyata J, Sato K, Hayashi A, et al. Transforming growth factor β stimulates rheumatoid synovial fibroblasts via the type II receptor. Mod Rheumatol 2005;15: 108-13.
-
(2005)
Mod Rheumatol
, vol.15
, pp. 108-113
-
-
Bira, Y.1
Tani, K.2
Nishioka, Y.3
Miyata, J.4
Sato, K.5
Hayashi, A.6
-
29
-
-
0344851619
-
Oxidised lipoproteins may promote inflammation through the selective delay of engulfment but not binding of apoptotic cells by macrophages
-
Khan M, Pelengaris S, Cooper M, Smith C, Evan G, Betteridge J. Oxidised lipoproteins may promote inflammation through the selective delay of engulfment but not binding of apoptotic cells by macrophages. Atherosclerosis 2003;171:21-9.
-
(2003)
Atherosclerosis
, vol.171
, pp. 21-29
-
-
Khan, M.1
Pelengaris, S.2
Cooper, M.3
Smith, C.4
Evan, G.5
Betteridge, J.6
-
30
-
-
0343484319
-
Central role of thrombospondin-1 in the activation and clonal expansion of inflammatory T cells
-
Vallejo AN, Mugge LO, Klimiuk PA, Weyand CM, Goronzy JJ. Central role of thrombospondin-1 in the activation and clonal expansion of inflammatory T cells. J Immunol 2000;164:2947-54.
-
(2000)
J Immunol
, vol.164
, pp. 2947-2954
-
-
Vallejo, A.N.1
Mugge, L.O.2
Klimiuk, P.A.3
Weyand, C.M.4
Goronzy, J.J.5
-
32
-
-
0031750927
-
Cysteine proteinase cathepsin K mRNA is expressed in synovium of patients with rheumatoid arthritis and is detected at sites of synovial bone destruction
-
Hummel KM, Petrow PK, Franz JK, Muller-Ladner U, Aicher WK, Gay RE, et al. Cysteine proteinase cathepsin K mRNA is expressed in synovium of patients with rheumatoid arthritis and is detected at sites of synovial bone destruction. J Rheumatol 1998;25:1887-94.
-
(1998)
J Rheumatol
, vol.25
, pp. 1887-1894
-
-
Hummel, K.M.1
Petrow, P.K.2
Franz, J.K.3
Muller-Ladner, U.4
Aicher, W.K.5
Gay, R.E.6
-
33
-
-
0028174609
-
Processing of interleukin-1 β in synovial cells freshly isolated from patients with rheumatoid arthritis
-
Kobayashi Y, Ichijo Y, Nagatake H, Watanabe N, Nishizawa K, Goto M. Processing of interleukin-1 β in synovial cells freshly isolated from patients with rheumatoid arthritis. Biochem Biophys Res Commun 1994;199:1035-4
-
(1994)
Biochem Biophys Res Commun
, vol.199
, pp. 1035-1044
-
-
Kobayashi, Y.1
Ichijo, Y.2
Nagatake, H.3
Watanabe, N.4
Nishizawa, K.5
Goto, M.6
-
34
-
-
33947730699
-
The role of IL-1 and IL-1Ra in joint inflammation and cartilage degradation
-
Jacques C, Gosset M, Berenbaum F, Gabay C. The role of IL-1 and IL-1Ra in joint inflammation and cartilage degradation. Vitam Horm 2006;74:371-403.
-
(2006)
Vitam Horm
, vol.74
, pp. 371-403
-
-
Jacques, C.1
Gosset, M.2
Berenbaum, F.3
Gabay, C.4
-
35
-
-
10344229958
-
Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis
-
Van Bilsen JH, van Dongen H, Lard LR, van der Voort EI, Elferink DG, Bakker AM, et al. Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis. Proc Natl Acad Sci U S A 2004;101:17180-5.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 17180-17185
-
-
Van Bilsen, J.H.1
van Dongen, H.2
Lard, L.R.3
van der Voort, E.I.4
Elferink, D.G.5
Bakker, A.M.6
-
36
-
-
11844264545
-
Induction of gene expression by 5-Aza-2′-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and independent mechanisms
-
Schmelz K, Sattler N, Wagner M, Lubbert M, Dorken B, Tamm I. Induction of gene expression by 5-Aza-2′-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and independent mechanisms. Leukemia 2005;19:103-11.
-
(2005)
Leukemia
, vol.19
, pp. 103-111
-
-
Schmelz, K.1
Sattler, N.2
Wagner, M.3
Lubbert, M.4
Dorken, B.5
Tamm, I.6
-
37
-
-
0036171225
-
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-Aza-2′-deoxycytidine
-
Liang G, Gonzales FA, Jones PA, Orntoft TF, Thykjaer T. Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-Aza-2′-deoxycytidine. Cancer Res 2002;62:961-6.
-
(2002)
Cancer Res
, vol.62
, pp. 961-966
-
-
Liang, G.1
Gonzales, F.A.2
Jones, P.A.3
Orntoft, T.F.4
Thykjaer, T.5
-
38
-
-
0037112369
-
Histone H3-Lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-Aza-2′-deoxycytidine
-
Nguyen CT, Weisenberger DJ, Velicescu M, Gonzales FA, Lin JC, Liang G, et al. Histone H3-Lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-Aza-2′-deoxycytidine. Cancer Res 2002;62:6456-61.
-
(2002)
Cancer Res
, vol.62
, pp. 6456-6461
-
-
Nguyen, C.T.1
Weisenberger, D.J.2
Velicescu, M.3
Gonzales, F.A.4
Lin, J.C.5
Liang, G.6
-
39
-
-
51649083501
-
A microRNA DNA methylation signature for human cancer metastasis
-
Lujambio A, Calin GA, Villanueva A, Ropero S, Sanchez-Cespedes M, Blanco D, et al. A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci U S A 2008;105:13556-61.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13556-13561
-
-
Lujambio, A.1
Calin, G.A.2
Villanueva, A.3
Ropero, S.4
Sanchez-Cespedes, M.5
Blanco, D.6
|