Differential thiol oxidation of the signaling proteins Akt, PTEN or PP2A determines whether Akt phosphorylation is enhanced or inhibited by oxidative stress in C2C12 myotubes derived from skeletal muscle

International Journal of Biochemistry and Cell Biology

Volumn 62, Issue , 2015, Pages 72-79

  Tan, Pearl Lin ^a   Shavlakadze, Tea ^a   Grounds, Miranda D ^a   Arthur, Peter G ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Akt; Hydrogen peroxide; Oxidative stress; Protein thiol oxidation; Reactive oxygen species

Indexed keywords

ANTIOXIDANT; CATALASE; GLUCOSE OXIDASE; HYDROGEN PEROXIDE; OXIDIZING AGENT; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; THIOL; PHOSPHOPROTEIN PHOSPHATASE 2; REACTIVE OXYGEN METABOLITE; THIOL DERIVATIVE;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; MOUSE; MYOTUBE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; SKELETAL MUSCLE; STIMULATION; ANIMAL; CELL LINE; DRUG EFFECTS; METABOLISM; OXIDATION REDUCTION REACTION; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE CELL;

ANIMALS; CELL LINE; HYDROGEN PEROXIDE; MICE; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SULFHYDRYL COMPOUNDS;

EID: 84924528082     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2015.02.015     Document Type: Article

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