Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 1, 2003, Pages 21-29

  Huang, Lily ^a   Brinen, Linda S ^b,c   Ellman, Jonathan A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRUZIPAIN; CYSTEINE PROTEINASE INHIBITOR; KETONE; KETONE DERIVATIVE;

ARTICLE; BINDING AFFINITY; COVALENT BOND; CRYSTAL STRUCTURE; PROTEIN BINDING; STRUCTURE ANALYSIS;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; KETONES; MODELS, MOLECULAR; PROTEIN BINDING; PROTOZOAN PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS; TRYPANOSOMA CRUZI;

EID: 6444244485     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00427-3     Document Type: Article

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