p53 protein oxidation in cultured cells in response to pyrrolidine dithiocarbamate: A novel method for relating the amount of p53 oxidation in vivo to the regulation of p53-responsive genes

Biochemical Journal

Volumn 351, Issue 1, 2000, Pages 87-93

  Wu, H H ^a   Thomas, J A ^a   Momand, J ^a  

^a CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

Methoxy polyethylene glycol maleimide; Nuclear accumulation; PDTC; Redox; Tumour suppressor

Indexed keywords

CYCLIN DEPENDENT KINASE; CYSTEINE; DACTINOMYCIN; DITHIOCARBAMIC ACID; MACROGOL DERIVATIVE; MALEIMIDE DERIVATIVE; ONCOPROTEIN; PROTEIN P21; PROTEIN P53; PYRROLIDINE DERIVATIVE;

ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL NUCLEUS; CELL STRAIN MCF 7; CONTROLLED STUDY; COVALENT BOND; CYTOPLASM; GENE CONTROL; HUMAN; HUMAN CELL; IN VIVO STUDY; OXIDATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

ANIMAL; CELL NUCLEUS; CHELATING AGENTS; CYCLINS; CYSTEINE; CYTOPLASM; DACTINOMYCIN; DISULFIDES; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HUMAN; MICE; ONCOGENE PROTEINS; OXIDATION-REDUCTION; POLYETHYLENE GLYCOLS; PROTEIN P53; PYRROLIDINES; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; THIOCARBAMATES; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0034306245     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3510087     Document Type: Article

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