Oxidative stress as a therapeutic target during muscle wasting: Considering the complex interactions

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 11, Issue 4, 2008, Pages 408-416

  Arthur, Peter G ^a   Grounds, Miranda D ^a   Shavlakadze, Thea ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Cachexia; Inflammation; Muscle wasting; Oxidative stress; Protein catabolism; Protein degradation; Reactive oxygen species; Sarcopenia; Signalling

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; CALCIUM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEASOME; PROTEIN KINASE B; PROTEINASE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

AUTOPHAGY; DISEASE EXACERBATION; IN VIVO STUDY; MACROMOLECULE; MUSCLE ATROPHY; MUSCLE MASS; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEGRADATION; REVIEW; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; CACHEXIA; HUMAN; METABOLISM; PHYSIOLOGY;

CACHEXIA; CALCIUM; HUMANS; MAP KINASE KINASE KINASE 5; MUSCULAR ATROPHY; NF-KAPPA B; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 54049086602     PISSN: 13631950     EISSN: 15353885     Source Type: Journal    
DOI: 10.1097/MCO.0b013e328302f3fe     Document Type: Review

References (68)

1. Shavlakadze T, Grounds M. Of bears, frogs, meat, mice and men: complexity of factors affecting skeletal muscle mass and fat. Bioessays 2006; 28:994- 1009.
2. Zurlo F, Larson K, Bogardus C, Ravussin E. Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest 1990; 86:1423-1427.
3. Moylan JS, Reid MB. Oxidative stress, chronic disease, and muscle wasting. Muscle Nerve 2007; 35:411-429.
4. Powers SK, Kavazis AN, McClung JM. Oxidative stress and disuse muscle atrophy. J Appl Physiol 2007; 102:2389-2397.
5. Radley HG, De Luca A, Lynch GS, Grounds MD. Duchenne muscular dystrophy: focus on pharmaceutical and nutritional interventions. Int J Bio-chem Cell Biol 2007; 39:469-477.
6. Szewczyk NJ, Jacobson LA. Signal-transduction networks and the regulation of muscle protein degradation. Int J BiochemCell Biol 2005; 37:1997-2011.
7. Brown RE, Jarvis KL, Hyland KJ. Protein measurement using bicinchoninic acid: elimination of interfering substances. Anal Biochem 1989; 180:136-139.
8. Tidball JG, Wehling-Henricks M. The role of free radicals in the pathophysiology of muscular dystrophy. J Appl Physiol 2007; 102:1677-1686.
9. Muller FL, Song W, Jang YC, et al. Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production. Am J Physiol Regul Integr Comp Physiol 2007; 293:R1159-R1168.
10. Muller FL, Song W, Liu Y, et al. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radic Biol Med 2006; 40:1993-2004.
11. Hansen RE, Ostergaard H, Norgaard P, Winther JR. Quantification of protein thiols and dithiols in the picomolar range using sodium borohydride and 4,4'-dithiodipyridine. Anal Biochem 2007; 363:77-82.
12. Howes RM. The free radical fantasy: a panoply of paradoxes. Ann N Y Acad Sci 2006; 1067:22-26.
13. Halliwell B, Gutteridge JMC. Free radicals in biology and medicine. 4th ed. Oxford; New York: Oxford University Press; 2007. 704 pp.
14. Stadtman ER, Levine RL. Chemical modificaton of proteins by reactive oxygen species. In: Dalle-Donne I, Scaloni A, Butterfield DA, editors. Redox proteo-mics: from protein modifications to cellular dysfunction and diseases. Wiley Press; 2006.
15. Droge W. Redox regulation in anabolic and catabolic processes. Curr Opin Clin Nutr Metab Care 2006; 9:190-195.
16. Bienert GP, Schjoerring JK, Jahn TP. Membrane transport of hydrogen peroxide. Biochim Biophys Acta 2006; 1758:994-1003.
17. Rhee SG. Cell signaling. H2O2, a necessary evil for cell signaling. Science 2006; 312:1882-1883.
18. Berndt C, Lillig CH, Holmgren A. Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. Am J Physiol Heart Circ Physiol 2007; 292:H1227-H1236.
19. Levine RL, Stadtman ER. Carbonylated proteins and their implication in physiology and pathology. In: Dalle-Donne I, Scaloni A, Butterfield DA, editors. Redox proteomics: from protein modifications to cellular dysfunction and diseases. Wiley Press; 2006.
20. Jung T, Bader N, Grune T. Oxidized proteins: intracellular distribution and recognition by the proteasome. Arch Biochem Biophys 2007; 462:231-237.
21. Jacob C, Knight I, Winyard PG. Aspects of the biological redox chemistry of cysteine: from simple redox responses to sophisticated signalling pathways. Biol Chem 2006; 387:1385-1397.
22. Milne GL, Yin H, Morrow JD. Human biochemistry of the isoprostane pathway. J Biol Chem 2008 [Epub ahead of print].
23. Cross JV, Templeton DJ. Regulation of signal transduction through protein cysteine oxidation. Antioxid Redox Signal 2006; 8:1819-1827.
24. Pantano C, Reynaert NL, van der Vliet A, Janssen-Heininger YM. Redox-sensitive kinases of the nuclear factor-kappaB signaling pathway. Antioxid Redox Signal 2006; 8:1791-1806.
25. Glass DJ. Skeletal muscle hypertrophy and atrophy signaling pathways. Int J Biochem Cell Biol 2005; 37:1974-1984.
26. Milne GL, Sanchez SC, Musiek ES, Morrow JD. Quantification of F2-isoprostanes as a biomarker of oxidative stress. Nat Protoc 2007; 2:221-226.
27. Clarke BA, Drujan D, Willis MS, et al. The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle. Cell Metab 2007; 6:376-385.
28. Grune T, Merker K, Sandig G, Davies KJ. Selective degradation of oxidatively modified protein substrates by the proteasome. Biochem Biophys Res Commun 2003; 305:709-718.
29. Bader N, Grune T. Protein oxidation and proteolysis. Biol Chem 2006 387:1351-1355.
30. Saez ME, Ramirez-Lorca R, Moron FJ, Ruiz A. The therapeutic potential of the calpain family: new aspects. Drug Discov Today 2006; 11:917-923.
31. Fareed MU, Evenson AR, Wei W, et al. Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent o atrogin-1/MAFbx and MuRF1 expression. Am J Physiol Regul Integr Comp Physiol 2006; 290:R1589-R1597.
32. Costelli P, Reffo P, Penna F, et al. Ca(2+)-dependent proteolysis in muscle wasting. Int J Biochem Cell Biol 2005; 37:2134-2146.
33. Kandarian SC, Jackman RW. Intracellular signaling during skeletal muscle atrophy. Muscle Nerve 2006; 33:155-165.
34. Mammucari C, Milan G, Romanello V, et al. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 2007; 6:458-471.
35. Zhao J, Brault JJ, Schild A, et al. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 2007; 6:472-483.
36. Scherz-Shouval R, Shvets E, Fass E, et al. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO 2007; 26:1749-1760.
37. Jahngen-Hodge J,Obin MS, Gong X, et al. Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress. J Biol Chem 1997 272:28218-28226.
38. Borutaite V, Brown GC. Caspases are reversibly inactivated by hydrogen peroxide. FEBS Lett 2001; 500:114-118.
39. Bubici C, Papa S, Dean K, Franzoso G. Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biologica significance. Oncogene 2006; 25:6731-6748.
40. Messina S, Altavilla D, Aguennouz M, et al. Lipid peroxidation inhibition blunts nuclear factor-kappaB activation, reduces skeletal muscle degeneration, and enhances muscle function in mdx mice. Am J Pathol 2006; 168:918-926.
41. Shen HM, Liu ZG. JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. Free Radic Biol Med 2006; 40:928-939.
42. Reynaert NL, van der Vliet A, Guala AS, et al. Dynamic redox control o NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proc Natl Acad Sci USA 2006; 103:13086-13091
43. Mourkioti F, Kratsios P, Luedde T, et al. Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. J Clin Invest 2006; 116:2945-2954.
44. Sompol P, Xu Y, Ittarat W, et al. NF-kappaB-associated MnSOD induction protects against beta-amyloid-induced neuronal apoptosis. J Mol Neurosc 2006; 29:279-288.
45. Murley JS, Kataoka Y, Weydert CJ, et al. Delayed radioprotection by nuclea transcription factor kappaB-mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065. Free Radic Biol Med 2006; 40:1004-1016.
46. Nadeau PJ, Charette SJ, Toledano MB, Landry J. Disulfide bond-mediated multimerization of Ask1 and its reduction by thioredoxin-1 regulate H(2)O(2) induced c-Jun NH(2)-terminal kinase activation and apoptosis. Mol Biol Cel 2007; 18:3903-3913.
47. Takeda K, Noguchi T, Naguro I, Ichijo H. Apoptosis signal-regulating kinase 1 in stress and immune response. Annu Rev Pharmacol Toxicol 2008; 48:199-225.
48. Huang H, Tindall DJ. Dynamic FoxO transcription factors. J Cell Sci 2007; 120:2479-2487.
49. den Hertog J, Ostman A, Bohmer FD. Protein tyrosine phosphatases: regulatory mechanisms. FEBS J 2008; 275:831-847.
50. Kohli R, Pan X, Malladi P, et al. Mitochondrial reactive oxygen species signal hepatocyte steatosis by regulating the phosphatidylinositol 3-kinase cell survival pathway. J Biol Chem 2007; 282:21327-21336.
51. Li M, Chiu JF, Mossman BT, Fukagawa NK. Down-regulation of manganese-superoxide dismutase through phosphorylation of FOXO3a by Akt in explanted vascular smooth muscle cells from old rats. J Biol Chem 2006; 281:40429-40439.
52. McClung JM, Kavazis AN, Whidden MA, et al. Antioxidant administration attenuates mechanical ventilation-induced rat diaphragm muscle atrophy independent of protein kinase B (PKB Akt) signalling. J Physiol 2007; 585:203-215.
53. Clavel S, Coldefy AS, Kurkdjian E, et al. Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle. Mech Ageing Dev 2006; 127:794-801.
54. Dalle-Donne I, Rossi R, Giustarini D, et al. S-glutathionylation in protein redox regulation. Free Radic Biol Med 2007; 43:883-898.
55. Ji LL. Antioxidant signaling in skeletal muscle: a brief review. Exp Gerontol 2007; 42:582-593.
56. Franklin RA, Rodriguez-Mora OG, Lahair MM, McCubrey JA. Activation of the calcium/calmodulin-dependent protein kinases as a consequence of oxidative stress. Antioxid Redox Signal 2006; 8:1807-1817.
57. Chinopoulos C, Adam-Vizi V. Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme. FEBS J 2006; 273:433-450.
58. 2+ channel function in the absence of apoptosis in ventricular myocytes. Circ Res 2007; 100:1036-1044.
59. +-ATPase in hydrogen peroxide-induced hypertrophy in cardiac myocytes. Free Radic Biol Med 2006; 41:1548-1556.
60. Whitehead NP, Yeung EW, Allen DG. Muscle damage in mdx (dystrophic) mice: role of calcium and reactive oxygen species. Clin Exp Pharmacol Physiol 2006; 33:657-662.
61. Arthur PG, Matich GP, Pang WW, et al. Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-jun N-terminal kinase. J Neurochem 2007; 102:65-76.
62. Casey TM, Arthur PG, Bogoyevitch MA. Necrotic death without mitochondrial dysfunction-delayed death of cardiac myocytes following oxidative stress. Biochim Biophys Acta 2007; 1773:342-351.
63. Grounds MD, Radley H, Gbeski B, et al. Implications of cross-talk between TNFa and IGF-1 signalling in skeletal muscle. Clin Exp Pharmacol Physiol 2008 [Epub ahead of print].
64. Schwabe RF, Brenner DA. Mechanisms of liver injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways. Am J Physiol Gastrointest Liver Physiol 2006; 290:G583-G589.
65. Gloire G, Legrand-Poels S, Piette J. NF-kappaB activation by reactive oxygen species: fifteen years later. Biochem Pharmacol 2006; 72:1493-1505.
66. Schaap LA, Pluijm SM, Deeg DJ, Visser M. Inflammatory markers and loss of muscle mass (sarcopenia) and strength. Am J Med 2006; 119:526.e9-526.e17.
67. Linnane AW, Eastwood H. Cellular redox regulation and prooxidant signaling systems: a new perspective on the free radical theory of aging. Ann N Y Acad Sci 2006; 1067:47-55.
68. Stone JR, Yang S. Hydrogen peroxide: a signaling messenger. Antioxid Redox Signal 2006; 8:243-270.