-
1
-
-
0042867423
-
Cellular regulation by hydrogen peroxide
-
Rhee S.G., Chang T.-S., Bae Y.S., Lee S.-R., and Kang S.W. Cellular regulation by hydrogen peroxide. J. Am. Soc. Nephrol. 14 (2003) S211-S215
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
-
-
Rhee, S.G.1
Chang, T.-S.2
Bae, Y.S.3
Lee, S.-R.4
Kang, S.W.5
-
2
-
-
0017939393
-
Biochemical mechanisms accounting for the toxic action of oxygen on living organisms: the key role of superoxide dismutase
-
Halliwell B. Biochemical mechanisms accounting for the toxic action of oxygen on living organisms: the key role of superoxide dismutase. Cell Biol. Int. Rep. 2 (1978) 113-128
-
(1978)
Cell Biol. Int. Rep.
, vol.2
, pp. 113-128
-
-
Halliwell, B.1
-
3
-
-
0035224049
-
Oxidative signalling and inflammatory pathways in Alzheimer's disease
-
Anderson I., Adinolfi C., Doctrow S., Huffman K., Joy K.A., Malfroy B., Soden P., Rupniak H.T., and Barnes J.C. Oxidative signalling and inflammatory pathways in Alzheimer's disease. Biochem. Soc. Symp. (2001) 141-149
-
(2001)
Biochem. Soc. Symp.
, pp. 141-149
-
-
Anderson, I.1
Adinolfi, C.2
Doctrow, S.3
Huffman, K.4
Joy, K.A.5
Malfroy, B.6
Soden, P.7
Rupniak, H.T.8
Barnes, J.C.9
-
4
-
-
24944525045
-
Molecular pathogenesis of Parkinson's disease
-
Gandhi S., and Wood N.W. Molecular pathogenesis of Parkinson's disease. Hum. Mol. Genet. 14 (2005) 2749-2755
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 2749-2755
-
-
Gandhi, S.1
Wood, N.W.2
-
5
-
-
0037327402
-
Oxidative stress and diabetic neuropathy: a new understanding of an old problem
-
Feldman E.L. Oxidative stress and diabetic neuropathy: a new understanding of an old problem. J. Clin. Invest. 111 (2003) 431-433
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 431-433
-
-
Feldman, E.L.1
-
6
-
-
4143110556
-
Oxidative stress in the pathogenesis of diabetic neuropathy
-
Vincent A.M., Russell J.W., Low P., and Feldman E.L. Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr. Rev. 25 (2004) 612-628
-
(2004)
Endocr. Rev.
, vol.25
, pp. 612-628
-
-
Vincent, A.M.1
Russell, J.W.2
Low, P.3
Feldman, E.L.4
-
8
-
-
84996120592
-
Oxidants and the central nervous system: some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke?
-
Halliwell B. Oxidants and the central nervous system: some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke?. Acta Neurol. Scand. Suppl. 126 (1989) 23-33
-
(1989)
Acta Neurol. Scand. Suppl.
, vol.126
, pp. 23-33
-
-
Halliwell, B.1
-
9
-
-
0034668057
-
Enhancement of T cell receptor signaling by a mild oxidative shift in the intracellular thiol pool
-
Hehner S.P., Breitkreutz R., Shubinsky G., Unsoeld H., Schulze-Osthoff K., Schmitz M.L., and Droge W. Enhancement of T cell receptor signaling by a mild oxidative shift in the intracellular thiol pool. J. Immunol. 165 (2000) 4319-4328
-
(2000)
J. Immunol.
, vol.165
, pp. 4319-4328
-
-
Hehner, S.P.1
Breitkreutz, R.2
Shubinsky, G.3
Unsoeld, H.4
Schulze-Osthoff, K.5
Schmitz, M.L.6
Droge, W.7
-
10
-
-
0033230607
-
Role of redox potential and reactive oxygen species in stress signaling
-
Adler V., Yin Z., Tew K.D., and Ronai Z. Role of redox potential and reactive oxygen species in stress signaling. Oncogene 18 (1999) 6104-6111
-
(1999)
Oncogene
, vol.18
, pp. 6104-6111
-
-
Adler, V.1
Yin, Z.2
Tew, K.D.3
Ronai, Z.4
-
12
-
-
0026700665
-
Macrophage tumoricidal mechanisms are selectively altered by prenatal chlordane exposure
-
Theus S.A., Tabor D.R., Soderberg L.S., and Barnett J.B. Macrophage tumoricidal mechanisms are selectively altered by prenatal chlordane exposure. Agents Actions 37 (1992) 140-146
-
(1992)
Agents Actions
, vol.37
, pp. 140-146
-
-
Theus, S.A.1
Tabor, D.R.2
Soderberg, L.S.3
Barnett, J.B.4
-
13
-
-
0029758783
-
Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways
-
Monteiro H.P., and Stern A. Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways. Free Radic. Biol. Med. 21 (1996) 323-333
-
(1996)
Free Radic. Biol. Med.
, vol.21
, pp. 323-333
-
-
Monteiro, H.P.1
Stern, A.2
-
14
-
-
33746833881
-
Free radical biology and medicine: it's a gas, man!
-
Pryor W.A., Houk K.N., Foote C.S., Fukuto J.M., Ignarro L.J., Squadrito G.L., and Davies K.J.A. Free radical biology and medicine: it's a gas, man!. Am. J. Physiol. Regul. Integr. Comp. Physiol. 291 (2006) R491-511
-
(2006)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.291
-
-
Pryor, W.A.1
Houk, K.N.2
Foote, C.S.3
Fukuto, J.M.4
Ignarro, L.J.5
Squadrito, G.L.6
Davies, K.J.A.7
-
15
-
-
1542514717
-
Thioredoxin regulation of ischemic preconditioning
-
Das D.K. Thioredoxin regulation of ischemic preconditioning. Antioxid. Redox Signal 6 (2004) 405-412
-
(2004)
Antioxid. Redox Signal
, vol.6
, pp. 405-412
-
-
Das, D.K.1
-
16
-
-
3042511840
-
Role of Akt Signaling in mitochondrial survival pathway triggered by hypoxic preconditioning
-
Uchiyama T., Engelman R.M., Maulik N., and Das D.K. Role of Akt Signaling in mitochondrial survival pathway triggered by hypoxic preconditioning. Circulation 109 (2004) 3042-3049
-
(2004)
Circulation
, vol.109
, pp. 3042-3049
-
-
Uchiyama, T.1
Engelman, R.M.2
Maulik, N.3
Das, D.K.4
-
18
-
-
0029074049
-
Hydrogen peroxide as a potent bacteriostatic antibiotic: implications for host defense
-
Hyslop P.A., Hinshaw D.B., Scraufstatter I.U., Cochrane C.G., Kunz S., and Vosbeck K. Hydrogen peroxide as a potent bacteriostatic antibiotic: implications for host defense. Free Radic. Biol. Med. 19 (1995) 31-37
-
(1995)
Free Radic. Biol. Med.
, vol.19
, pp. 31-37
-
-
Hyslop, P.A.1
Hinshaw, D.B.2
Scraufstatter, I.U.3
Cochrane, C.G.4
Kunz, S.5
Vosbeck, K.6
-
19
-
-
0032527705
-
The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival
-
Wang X., Martindale J.L., Liu Y., and Holbrook N.J. The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem. J. 333 Pt 2 (1998) 291
-
(1998)
Biochem. J.
, vol.333
, Issue.PART 2
, pp. 291
-
-
Wang, X.1
Martindale, J.L.2
Liu, Y.3
Holbrook, N.J.4
-
21
-
-
0025739254
-
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
-
Schreck R., Rieber P., and Baeuerle P.A. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 10 (1991) 2247
-
(1991)
EMBO J.
, vol.10
, pp. 2247
-
-
Schreck, R.1
Rieber, P.2
Baeuerle, P.A.3
-
22
-
-
0033578648
-
Dual role of reactive oxygen species in vascular growth
-
Griendling K.K., and Harrison D.G. Dual role of reactive oxygen species in vascular growth. Circ. Res. 85 (1999) 562
-
(1999)
Circ. Res.
, vol.85
, pp. 562
-
-
Griendling, K.K.1
Harrison, D.G.2
-
23
-
-
33847349283
-
Reactive oxygen species: a breath of life or death?
-
Fruehauf J.P., and Meyskens Jr. F.L. Reactive oxygen species: a breath of life or death?. Clin. Cancer Res. 13 (2007) 789-794
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 789-794
-
-
Fruehauf, J.P.1
Meyskens Jr., F.L.2
-
24
-
-
0034640524
-
Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival
-
Wang X., McCullough K.D., Franke T.F., and Holbrook N.J. Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival. J. Biol. Chem. 275 (2000) 14624-14631
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14624-14631
-
-
Wang, X.1
McCullough, K.D.2
Franke, T.F.3
Holbrook, N.J.4
-
25
-
-
0033529675
-
Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells
-
Ushio-Fukai M., Alexander R.W., Akers M., Yin Q., Fujio Y., Walsh K., and Griendling K.K. Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells. J. Biol. Chem. 274 (1999) 22699-22704
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22699-22704
-
-
Ushio-Fukai, M.1
Alexander, R.W.2
Akers, M.3
Yin, Q.4
Fujio, Y.5
Walsh, K.6
Griendling, K.K.7
-
26
-
-
0030785701
-
Kuroda S., Ono Y, Kikkawa U, Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27
-
Konishi H., Matsuzaki H., Tanaka M., and Takemura Y. Kuroda S., Ono Y, Kikkawa U, Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27. FEBS Lett. 410 (1997) 493-498
-
(1997)
FEBS Lett.
, vol.410
, pp. 493-498
-
-
Konishi, H.1
Matsuzaki, H.2
Tanaka, M.3
Takemura, Y.4
-
27
-
-
27544446991
-
Life in the balance: how BH3-only proteins induce apoptosis
-
Willis S.N., and Adams J.M. Life in the balance: how BH3-only proteins induce apoptosis. Curr. Opin. Cell Biol. 17 (2005) 617-625
-
(2005)
Curr. Opin. Cell Biol.
, vol.17
, pp. 617-625
-
-
Willis, S.N.1
Adams, J.M.2
-
28
-
-
0031660082
-
Mutagenesis of the BH3 Domain of BAX identifies residues critical for dimerization and killing
-
Wang K., Gross A., Waksman G., and Korsmeyer S.J. Mutagenesis of the BH3 Domain of BAX identifies residues critical for dimerization and killing. Mol. Cell. Biol. 18 (1998) 6083-6089
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6083-6089
-
-
Wang, K.1
Gross, A.2
Waksman, G.3
Korsmeyer, S.J.4
-
29
-
-
0031459534
-
Regulation of apoptosis by BH3 domains in a cell-free system
-
Cosulich S.C., Worrall V., Hedge P.J., Green S., and Clarke P.R. Regulation of apoptosis by BH3 domains in a cell-free system. Curr. Biol. 7 (1997) 913-920
-
(1997)
Curr. Biol.
, vol.7
, pp. 913-920
-
-
Cosulich, S.C.1
Worrall, V.2
Hedge, P.J.3
Green, S.4
Clarke, P.R.5
-
30
-
-
15444371092
-
Nicotine inactivation of the proapoptotic function of Bax through phosphorylation
-
Xin M., and Deng X. Nicotine inactivation of the proapoptotic function of Bax through phosphorylation. J. Biol. Chem. 280 (2005) 10781-10789
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 10781-10789
-
-
Xin, M.1
Deng, X.2
-
31
-
-
2442681877
-
Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils
-
Gardai S.J., Hildeman D.A., Frankel S.K., Whitlock B.B., Frasch S.C., Borregaard N., Marrack P., Bratton D.L., and Henson P.M. Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils. J. Biol. Chem. 279 (2004) 21085-21095
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21085-21095
-
-
Gardai, S.J.1
Hildeman, D.A.2
Frankel, S.K.3
Whitlock, B.B.4
Frasch, S.C.5
Borregaard, N.6
Marrack, P.7
Bratton, D.L.8
Henson, P.M.9
-
32
-
-
0033987491
-
Insulin-like growth factor I is the key growth factor in serum that protects neuroblastoma cells from hyperosmotic-induced apoptosis
-
Van Golen C.M., and Feldman E.L. Insulin-like growth factor I is the key growth factor in serum that protects neuroblastoma cells from hyperosmotic-induced apoptosis. J. Cell. Physiol. 182 (2000) 24-32
-
(2000)
J. Cell. Physiol.
, vol.182
, pp. 24-32
-
-
Van Golen, C.M.1
Feldman, E.L.2
-
33
-
-
0037178855
-
Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt
-
Kim B., and Feldman E.L. Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt. J. Biol. Chem. 277 (2002) 27393-27400
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27393-27400
-
-
Kim, B.1
Feldman, E.L.2
-
34
-
-
0035829692
-
Insulin-like growth factor I stimulates motility in human neuroblastoma cells
-
Meyer G.E., Shelden E., Kim B., and Feldman E.L. Insulin-like growth factor I stimulates motility in human neuroblastoma cells. Oncogene 20 (2001) 7542-7550
-
(2001)
Oncogene
, vol.20
, pp. 7542-7550
-
-
Meyer, G.E.1
Shelden, E.2
Kim, B.3
Feldman, E.L.4
-
35
-
-
27844549786
-
Insulin-like growth factor I induces preferential degradation of insulin receptor substrate-2 through the phosphatidylinositol 3-kinase pathway in human neuroblastoma cells
-
Kim B., van Golen C.M., and Feldman E.L. Insulin-like growth factor I induces preferential degradation of insulin receptor substrate-2 through the phosphatidylinositol 3-kinase pathway in human neuroblastoma cells. Endocrinology 146 (2005) 5350-5357
-
(2005)
Endocrinology
, vol.146
, pp. 5350-5357
-
-
Kim, B.1
van Golen, C.M.2
Feldman, E.L.3
-
36
-
-
23944475155
-
Insulin-like growth factor-I induces the phosphorylation and nuclear exclusion of forkhead transcription factors in human neuroblastoma cells
-
Schwab T.S., Madison B.B., Grauman A.R., and Feldman E.L. Insulin-like growth factor-I induces the phosphorylation and nuclear exclusion of forkhead transcription factors in human neuroblastoma cells. Apoptosis 10 (2005) 831-840
-
(2005)
Apoptosis
, vol.10
, pp. 831-840
-
-
Schwab, T.S.1
Madison, B.B.2
Grauman, A.R.3
Feldman, E.L.4
-
37
-
-
0028884767
-
Insulin-like growth factor-II as a paracrine growth factor in human neuroblastoma cells
-
Leventhal P.S., Randolph A.E., Vesbit T.E., Schenone A., Windebank A.J., and Feldman E.L. Insulin-like growth factor-II as a paracrine growth factor in human neuroblastoma cells. Exp. Cell Res. 221 (1995) 179-186
-
(1995)
Exp. Cell Res.
, vol.221
, pp. 179-186
-
-
Leventhal, P.S.1
Randolph, A.E.2
Vesbit, T.E.3
Schenone, A.4
Windebank, A.J.5
Feldman, E.L.6
-
38
-
-
0034697148
-
Src and Cas Mediate JNK Activation but Not ERK1/2 and p38 Kinases by Reactive Oxygen Species
-
Yoshizumi M., Abe J.-i., Haendeler J., Huang Q., and Berk B.C. Src and Cas Mediate JNK Activation but Not ERK1/2 and p38 Kinases by Reactive Oxygen Species. J. Biol. Chem. 275 (2000) 11706-11712
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 11706-11712
-
-
Yoshizumi, M.1
Abe, J.-i.2
Haendeler, J.3
Huang, Q.4
Berk, B.C.5
-
39
-
-
0034677930
-
Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress
-
Sun X., Wu F., Datta R., Kharbanda S., and Kufe D. Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress. J. Biol. Chem. 275 (2000) 7470-7473
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7470-7473
-
-
Sun, X.1
Wu, F.2
Datta, R.3
Kharbanda, S.4
Kufe, D.5
-
40
-
-
0034674055
-
2 gradients across biomembranes
-
2 gradients across biomembranes. FEBS Lett. 475 (2000) 121-126
-
(2000)
FEBS Lett.
, vol.475
, pp. 121-126
-
-
Antunes, F.1
Cadenas, E.2
-
41
-
-
0034704394
-
IGF-I promotes Schwann cell motility and survival via activation of Akt
-
Cheng H.L., Steinway M., Delaney C.L., Franke T.F., and Feldman E.L. IGF-I promotes Schwann cell motility and survival via activation of Akt. Mol. Cell. Endocrinol. 170 (2000) 211-215
-
(2000)
Mol. Cell. Endocrinol.
, vol.170
, pp. 211-215
-
-
Cheng, H.L.1
Steinway, M.2
Delaney, C.L.3
Franke, T.F.4
Feldman, E.L.5
-
42
-
-
0031846706
-
Differential regulation of focal adhesion kinase and mitogen-activated protein kinase tyrosine phosphorylation during insulin-like growth factor-I-mediated cytoskeletal reorganization
-
Kim B., and Feldman E.L. Differential regulation of focal adhesion kinase and mitogen-activated protein kinase tyrosine phosphorylation during insulin-like growth factor-I-mediated cytoskeletal reorganization. J. Neurochem. 71 (1998) 1333-1336
-
(1998)
J. Neurochem.
, vol.71
, pp. 1333-1336
-
-
Kim, B.1
Feldman, E.L.2
-
43
-
-
0029778530
-
Type I insulin-like growth factor receptor activation regulates apoptotic proteins
-
Singleton J.R., Dixit V.M., and Feldman E.L. Type I insulin-like growth factor receptor activation regulates apoptotic proteins. J. Biol. Chem. 271 (1996) 31791-31794
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31791-31794
-
-
Singleton, J.R.1
Dixit, V.M.2
Feldman, E.L.3
-
44
-
-
0028036487
-
Methods for the detection of apoptosis
-
Sgonc R., and Wick G. Methods for the detection of apoptosis. Int. Arch. Allergy Immunol. 105 (1994) 327-332
-
(1994)
Int. Arch. Allergy Immunol.
, vol.105
, pp. 327-332
-
-
Sgonc, R.1
Wick, G.2
-
45
-
-
0028028307
-
Multi-step chromatin degradation in apoptosis. DNA breakdown in apoptosis
-
Kokileva L. Multi-step chromatin degradation in apoptosis. DNA breakdown in apoptosis. Int. Arch. Allergy Immunol. 105 (1994) 339-343
-
(1994)
Int. Arch. Allergy Immunol.
, vol.105
, pp. 339-343
-
-
Kokileva, L.1
-
46
-
-
0038192242
-
N-Myc overexpression leads to decreased beta1 integrin expression and increased apoptosis in human neuroblastoma cells
-
van Golen C.M., Soules M.E., Grauman A.R., and Feldman E.L. N-Myc overexpression leads to decreased beta1 integrin expression and increased apoptosis in human neuroblastoma cells. Oncogene 22 (2003) 2664-2673
-
(2003)
Oncogene
, vol.22
, pp. 2664-2673
-
-
van Golen, C.M.1
Soules, M.E.2
Grauman, A.R.3
Feldman, E.L.4
-
47
-
-
0043193866
-
Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis
-
Chiang C.W., Kanies C., Kim K.W., Fang W.B., Parkhurst C., Xie M., Henry T., and Yang E. Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis. Mol. Cell. Biol. 23 (2003) 6350-6362
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6350-6362
-
-
Chiang, C.W.1
Kanies, C.2
Kim, K.W.3
Fang, W.B.4
Parkhurst, C.5
Xie, M.6
Henry, T.7
Yang, E.8
-
48
-
-
0033713002
-
Structure of Bax: coregulation of dimer formation and intracellular localization
-
Suzuki M., Youle R.J., and Tjandra N. Structure of Bax: coregulation of dimer formation and intracellular localization. Cell 103 (2000) 645-654
-
(2000)
Cell
, vol.103
, pp. 645-654
-
-
Suzuki, M.1
Youle, R.J.2
Tjandra, N.3
-
49
-
-
33746881744
-
Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1
-
Leinninger G.M., Backus C., Sastry A.M., Yi Y.B., Wang C.W., and Feldman E.L. Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1. Neurobiol. Dis. 23 (2006) 11-22
-
(2006)
Neurobiol. Dis.
, vol.23
, pp. 11-22
-
-
Leinninger, G.M.1
Backus, C.2
Sastry, A.M.3
Yi, Y.B.4
Wang, C.W.5
Feldman, E.L.6
-
50
-
-
1842613595
-
Conformational control of Bax localization and apoptotic activity by Pro168
-
Schinzel A., Kaufmann T., Schuler M., Martinalbo J., Grubb D., and Borner C. Conformational control of Bax localization and apoptotic activity by Pro168. J. Cell Biol. 164 (2004) 1021-1032
-
(2004)
J. Cell Biol.
, vol.164
, pp. 1021-1032
-
-
Schinzel, A.1
Kaufmann, T.2
Schuler, M.3
Martinalbo, J.4
Grubb, D.5
Borner, C.6
-
51
-
-
0032574761
-
Bax directly induces release of cytochrome c from isolated mitochondria
-
Jurgensmeier J.M., Xie Z., Deveraux Q., Ellerby L., Bredesen D., and Reed J.C. Bax directly induces release of cytochrome c from isolated mitochondria. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 4997-5002
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 4997-5002
-
-
Jurgensmeier, J.M.1
Xie, Z.2
Deveraux, Q.3
Ellerby, L.4
Bredesen, D.5
Reed, J.C.6
-
52
-
-
0036845661
-
High glucose-induced oxidative stress and mitochondrial dysfunction in neurons
-
Russell J.W., Golovoy D., Vincent A.M., Mahendru P.I.A., Olzmann J.A., Mentzer A., and Feldman E.L. High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB J. 16 (2002) 1738-1748
-
(2002)
FASEB J.
, vol.16
, pp. 1738-1748
-
-
Russell, J.W.1
Golovoy, D.2
Vincent, A.M.3
Mahendru, P.I.A.4
Olzmann, J.A.5
Mentzer, A.6
Feldman, E.L.7
-
53
-
-
0036019941
-
Redox-linked signal transduction pathways for protein tyrosine kinase activation
-
Nakashima I., Kato M., Akhand A.A., Suzuki H., Takeda K., Hossain K., and Kawamoto Y. Redox-linked signal transduction pathways for protein tyrosine kinase activation. Antioxid. Redox Signal 4 (2002) 517-531
-
(2002)
Antioxid. Redox Signal
, vol.4
, pp. 517-531
-
-
Nakashima, I.1
Kato, M.2
Akhand, A.A.3
Suzuki, H.4
Takeda, K.5
Hossain, K.6
Kawamoto, Y.7
-
54
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K., Xia Y., Zweier J.L., Sollott S.J., Der C.J., Fearon E.R., Sundaresan M., Finkel T., and Goldschmidt-Clermont P.J. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275 (1997) 1649-1652
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
55
-
-
0025197060
-
2 and vanadate concomitantly stimulates protein tyrosine phosphorylation and polyphosphoinositide breakdown in different cell lines
-
2 and vanadate concomitantly stimulates protein tyrosine phosphorylation and polyphosphoinositide breakdown in different cell lines. Biochemistry 29 (1990) 10240-10245
-
(1990)
Biochemistry
, vol.29
, pp. 10240-10245
-
-
Zick, Y.1
Sagi-Eisenberg, R.2
-
56
-
-
0032554611
-
Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation
-
Denu J.M., and Tanner K.G. Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation. Biochemistry 37 (1998) 5633-5642
-
(1998)
Biochemistry
, vol.37
, pp. 5633-5642
-
-
Denu, J.M.1
Tanner, K.G.2
-
58
-
-
18544386962
-
Oxidation and tyrosine phosphorylation: synergistic or antagonistic cues in protein tyrosine phosphatase
-
Chiarugi P., Taddei M.L., and Ramponi G. Oxidation and tyrosine phosphorylation: synergistic or antagonistic cues in protein tyrosine phosphatase. Cell. Mol. Life Sci. 62 (2005) 931-936
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 931-936
-
-
Chiarugi, P.1
Taddei, M.L.2
Ramponi, G.3
-
59
-
-
0030884103
-
PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond
-
Marte B.M., and Downward J. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem. Sci. 22 (1997) 355-358
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 355-358
-
-
Marte, B.M.1
Downward, J.2
-
60
-
-
0032752063
-
Cellular survival: a play in three Akts
-
Datta S.R., Brunet A., and Greenberg M.E. Cellular survival: a play in three Akts. Genes Dev. 13 (1999) 2905-2927
-
(1999)
Genes Dev.
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
61
-
-
9444237919
-
Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons
-
Leinninger G.M., Backus C., Uhler M.D., Lentz S.I., and Feldman E.L. Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons. FASEB J. 18 (2004) 1544-1546
-
(2004)
FASEB J.
, vol.18
, pp. 1544-1546
-
-
Leinninger, G.M.1
Backus, C.2
Uhler, M.D.3
Lentz, S.I.4
Feldman, E.L.5
-
62
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Dudek H., Datta S.R., Franke T.F., Birnbaum M.J., Yao R., Cooper G.M., Segal R.A., Kaplan D.R., and Greenberg M.E. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275 (1997) 661-665
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
63
-
-
0030890933
-
Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
-
Ahmed N.N., Grimes H.L., Bellacosa A., Chan T.O., and Tsichlis P.N. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 3627-3632
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 3627-3632
-
-
Ahmed, N.N.1
Grimes, H.L.2
Bellacosa, A.3
Chan, T.O.4
Tsichlis, P.N.5
-
64
-
-
0031028730
-
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB
-
Kauffmann-Zeh A., Rodriguez-Viciana P., Ulrich E., Gilbert C., Coffer P., Downward J., and Evan G. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. Nature 385 (1997) 544-548
-
(1997)
Nature
, vol.385
, pp. 544-548
-
-
Kauffmann-Zeh, A.1
Rodriguez-Viciana, P.2
Ulrich, E.3
Gilbert, C.4
Coffer, P.5
Downward, J.6
Evan, G.7
-
65
-
-
0030904561
-
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal
-
Kennedy S.G., Wagner A.J., Conzen S.D., Jordan J., Bellacosa A., Tsichlis P.N., and Hay N. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev. 11 (1997) 701-713
-
(1997)
Genes Dev.
, vol.11
, pp. 701-713
-
-
Kennedy, S.G.1
Wagner, A.J.2
Conzen, S.D.3
Jordan, J.4
Bellacosa, A.5
Tsichlis, P.N.6
Hay, N.7
-
66
-
-
0033010059
-
Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis
-
McGinnis K.M., Gnegy M.E., and Wang K.K. Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis. J. Neurochem. 72 (1999) 1899-1906
-
(1999)
J. Neurochem.
, vol.72
, pp. 1899-1906
-
-
McGinnis, K.M.1
Gnegy, M.E.2
Wang, K.K.3
-
67
-
-
0030702123
-
Akt Phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., and Greenberg M.E. Akt Phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91 (1997) 231-241
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
68
-
-
0142027948
-
Ways of dying: multiple pathways to apoptosis
-
Adams J.M. Ways of dying: multiple pathways to apoptosis. Genes Dev. 17 (2003) 2481-2495
-
(2003)
Genes Dev.
, vol.17
, pp. 2481-2495
-
-
Adams, J.M.1
-
69
-
-
0033937809
-
IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma
-
van Golen C.M., Castle V.P., and Feldman E.L. IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma. Cell Death Differ. 7 (2000) 654-665
-
(2000)
Cell Death Differ.
, vol.7
, pp. 654-665
-
-
van Golen, C.M.1
Castle, V.P.2
Feldman, E.L.3
-
70
-
-
1842333237
-
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
-
del Peso L., Gonzalez-Garcia M., Page C., Herrera R., and Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278 (1997) 687-689
-
(1997)
Science
, vol.278
, pp. 687-689
-
-
del Peso, L.1
Gonzalez-Garcia, M.2
Page, C.3
Herrera, R.4
Nunez, G.5
-
71
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
Adams J.M., and Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26 (2007) 1324-1337
-
(2007)
Oncogene
, vol.26
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
72
-
-
0033522391
-
Conformation of the Bax C-terminus regulates subcellular location and cell death
-
Nechushtan A., Smith C.L., Hsu Y.T., and Youle R.J. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J. 18 (1999) 2330-2341
-
(1999)
EMBO J.
, vol.18
, pp. 2330-2341
-
-
Nechushtan, A.1
Smith, C.L.2
Hsu, Y.T.3
Youle, R.J.4
-
73
-
-
0033545722
-
Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations
-
Basanez G., Nechushtan A., Drozhinin O., Chanturiya A., Choe E., Tutt S., Wood K.A., Hsu Y.T., Zimmerberg J., and Youle R.J. Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 5492-5497
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 5492-5497
-
-
Basanez, G.1
Nechushtan, A.2
Drozhinin, O.3
Chanturiya, A.4
Choe, E.5
Tutt, S.6
Wood, K.A.7
Hsu, Y.T.8
Zimmerberg, J.9
Youle, R.J.10
-
74
-
-
0035853811
-
Martinou J-C, Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
-
Antonsson B., Montessuit S., and Sanchez B. Martinou J-C, Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. J. Biol. Chem. 276 (2001) 11615-11623
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11615-11623
-
-
Antonsson, B.1
Montessuit, S.2
Sanchez, B.3
-
75
-
-
0032487582
-
Regulated targeting of BAX to mitochondria
-
Goping I.S., Gross A., Lavoie J.N., Nguyen M., Jemmerson R., Roth K., Korsmeyer S.J., and Shore G.C. Regulated targeting of BAX to mitochondria. J. Cell Biol. 143 (1998) 207-215
-
(1998)
J. Cell Biol.
, vol.143
, pp. 207-215
-
-
Goping, I.S.1
Gross, A.2
Lavoie, J.N.3
Nguyen, M.4
Jemmerson, R.5
Roth, K.6
Korsmeyer, S.J.7
Shore, G.C.8
-
76
-
-
0034655408
-
Cytochrome c release and caspase activation in traumatic axonal injury
-
Buki A., Okonkwo D.O., Wang K.K., and Povlishock J.T. Cytochrome c release and caspase activation in traumatic axonal injury. J. Neurosci. 20 (2000) 2825-2834
-
(2000)
J. Neurosci.
, vol.20
, pp. 2825-2834
-
-
Buki, A.1
Okonkwo, D.O.2
Wang, K.K.3
Povlishock, J.T.4
-
77
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., and Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91 (1997) 479-489
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
78
-
-
0034023082
-
Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from Parkinsonian brain
-
Mogi M., Togari A., Kondo T., Mizuno Y., Komure O., Kuno S., Ichinose H., and Nagatsu T. Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from Parkinsonian brain. J. Neural Transm. 107 (2000) 335-341
-
(2000)
J. Neural Transm.
, vol.107
, pp. 335-341
-
-
Mogi, M.1
Togari, A.2
Kondo, T.3
Mizuno, Y.4
Komure, O.5
Kuno, S.6
Ichinose, H.7
Nagatsu, T.8
-
79
-
-
0033912716
-
Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease
-
Chen M., Ona V.O., Li M., Ferrante R.J., Fink K.B., Zhu S., Bian J., Guo L., Farrell L.A., Hersch S.M., Hobbs W., Vonsattel J.P., Cha J.H., and Friedlander R.M. Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease. Nat. Med. 6 (2000) 797-801
-
(2000)
Nat. Med.
, vol.6
, pp. 797-801
-
-
Chen, M.1
Ona, V.O.2
Li, M.3
Ferrante, R.J.4
Fink, K.B.5
Zhu, S.6
Bian, J.7
Guo, L.8
Farrell, L.A.9
Hersch, S.M.10
Hobbs, W.11
Vonsattel, J.P.12
Cha, J.H.13
Friedlander, R.M.14
-
80
-
-
0041335559
-
Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease
-
Wang X., Zhu S., Drozda M., Zhang W., Stavrovskaya I.G., Cattaneo E., Ferrante R.J., Kristal B.S., and Friedlander R.M. Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 10483-10487
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 10483-10487
-
-
Wang, X.1
Zhu, S.2
Drozda, M.3
Zhang, W.4
Stavrovskaya, I.G.5
Cattaneo, E.6
Ferrante, R.J.7
Kristal, B.S.8
Friedlander, R.M.9
-
81
-
-
0027257708
-
Apoptosis is induced by {beta}-amyloid in cultured central nervous system neurons
-
Loo D.T., Copani A., Pike C.J., Whittemore E.R., Walencewicz A.J., and Cotman C.W. Apoptosis is induced by {beta}-amyloid in cultured central nervous system neurons. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 7951-7955
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 7951-7955
-
-
Loo, D.T.1
Copani, A.2
Pike, C.J.3
Whittemore, E.R.4
Walencewicz, A.J.5
Cotman, C.W.6
|