Induction of protein catabolism and the ubiquitin-proteasome pathway by mild oxidative stress

Cancer Letters

Volumn 180, Issue 1, 2002, Pages 69-74

  Gomes Marcondes, Maria Cristina C ^a   Tisdale, Michael J ^b  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b ASTON UNIVERSITY   (United Kingdom)

Author keywords

Oxidative stress; Proteasome expression; Proteolysis

Indexed keywords

FERROUS SULFATE; HYDROGEN PEROXIDE; MALONALDEHYDE; MUSCLE PROTEIN; MYOSIN; PROTEASOME; PROTEIN P42; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME;

ALPHA CHAIN; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CACHEXIA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBUNIT; EXPERIMENTAL MODEL; IMMUNOBLOTTING; MOUSE; MOUSE STRAIN; MUSCLE ATROPHY; MYOTUBE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ANIMALS; BLOTTING, WESTERN; CACHEXIA; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; EGG PROTEINS; MALONDIALDEHYDE; MEMBRANE GLYCOPROTEINS; MICE; MULTIENZYME COMPLEXES; MUSCLE, SKELETAL; MYOSINS; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; RECEPTORS, CELL SURFACE; TIME FACTORS; UBIQUITIN;

EID: 0037030584     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(02)00006-X     Document Type: Article

References (15)

1. Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states
2. 14-kDa ubiquitin-conjugating enzyme: Structure of the rat gene and regulation upon fasting and by insulin
3. Increased ATP-ubiquitin-dependent proteolysis in skeletal muscles of tumor-bearing rats
4. Muscle wasting and dedifferentiation induced by oxidative stress in a murine model of cachexia is prevented by inhibitors of nitric oxide synthesis and antioxidants
5. Novel anti-tumour activity of 2,3,5-trimethyl-6-(3-pyridylmethyl)-1,4-benzoquinone (CV-6504) against established murine adenocarcinomas (MAC)
6. Tumour necrosis factor-alpha induces superoxide anion generation in mitochondria of L929 cells
7. Reactive oxygen in skeletal muscle. II. Extracellular release of free radicals
8. Production of lipolytic and proteolytic factors by a murine tumor-producing cachexia in the host
9. ATP-dependent reversible association of proteasomes with multiple protein components to form 26S complexes that degrade ubiquitinated proteins in human HL-60 cells
10. Mechanism of muscle protein degradation induced by a cancer cachectic factor
11. The proteasome-dependent proteolytic system
12. Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome
13. Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress
14. Proteasome activation by poly-ADP-ribose-polymerase in human myelomonocytic cells after oxidative stress
15. Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-kappaB activation in response to tumor necrosis factor alpha