Redox modification of Akt mediated by the dopaminergic neurotoxin MPTP, in mouse midbrain, leads to down-regulation of pAkt

FASEB Journal

Volumn 26, Issue 4, 2012, Pages 1473-1483

  Durgadoss, Lalitha ^a   Nidadavolu, Prakash ^a,b   Valli, Rupanagudi Khader ^a   Saeed, Uzma ^a   Mishra, Mamata ^a   Seth, Pankaj ^a   Ravindranath, Vijayalakshmi ^a,b  

^a NATIONAL BRAIN RESEARCH CENTRE   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Glutaredoxin; Protein phosphatase 2A; Protein thiol; Thiol antioxidants

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ANTIOXIDANT; APOPTOSIS SIGNAL REGULATING KINASE 1; BETA CATENIN; BETA TUBULIN; CYSTEINE DERIVATIVE; GLUTAREDOXIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE H3; NEUROTOXIN; OXIDOREDUCTASE; PHOSPHATASE; PHOSPHATASE PP2A; PROTEIN DISULFIDE OXIDOREDUCTASE; PROTEIN KINASE B; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXPOSURE; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VIVO STUDY; MESENCEPHALON; MOUSE; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; SIGNAL TRANSDUCTION;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; DOPAMINE; DOPAMINERGIC NEURONS; DOWN-REGULATION; HERBICIDES; HUMANS; MALE; MESENCEPHALON; MICE; MICE, INBRED C57BL; MPTP POISONING; OXIDATION-REDUCTION; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; STEM CELLS; SULFHYDRYL COMPOUNDS;

MUS;

EID: 84860908312     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-194100     Document Type: Article

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