Hydrogen peroxide inhibits insulin signaling in vascular smooth muscle cells

Experimental Biology and Medicine

Volumn 228, Issue 7, 2003, Pages 836-842

  Gardner, Carla D ^a   Eguchi, Satoru ^b   Reynolds, Cherilynn M ^a   Eguchi, Kunie ^a   Frank, Gerald D ^b   Motley, Evangeline D ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; Hydrogen peroxide; Insulin resistance; Protein kinase B; Vascular smooth muscle cells

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; DIAMIDE; HYDROGEN PEROXIDE; INSULIN; INSULIN RECEPTOR; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; REACTIVE OXYGEN METABOLITE; AKT1 PROTEIN, RAT; BISINDOLYLMALEIMIDE I; ENZYME INHIBITOR; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; ONCOPROTEIN; SERINE;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; CARDIOVASCULAR DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HORMONE ACTION; HORMONE RECEPTOR INTERACTION; IN VIVO STUDY; INSULIN RESISTANCE; NONHUMAN; PATHOPHYSIOLOGY; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TIME; VASCULAR SMOOTH MUSCLE; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INTERACTION; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; DIAMIDE; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INHIBITORS; HYDROGEN PEROXIDE; INDOLES; INSULIN; MALEIMIDES; MUSCLE, SMOOTH, VASCULAR; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; SERINE; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 0141679355     PISSN: 15353702     EISSN: None     Source Type: Journal    
DOI: 10.1177/15353702-0322807-09     Document Type: Article

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