Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance

Cell Metabolism

Volumn 21, Issue 3, 2015, Pages 403-416

  Kraakman, Michael J ^a   Kammoun, Helene L ^a   Allen, Tamara L ^a   Deswaerte, Virginie ^a   Henstridge, Darren C ^a   Estevez, Emma ^a   Matthews, Vance B ^a   Neill, Bronwyn ^a   White, David A ^a   Murphy, Andrew J ^a   Peijs, Lone ^a   Yang, Christine ^a   Risis, Steve ^a   Bruce, Clinton R ^a   Du, Xiao Jun ^a   Bobik, Alex ^a   Lee Young, Robert S ^a   Kingwell, Bronwyn A ^a   Vasanthakumar, Ajithkumar ^b   Shi, Wei ^b,c   Kallies, Axel ^b   Lancaster, Graeme I ^a   Rose John, Stefan ^d   Febbraio, Mark A ^a   more..

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CCAAT ENHANCER BINDING PROTEIN BETA; FATTY ACID BINDING PROTEIN 4; GLYCOPROTEIN; GLYCOPROTEIN GP 130; HEMOGLOBIN A1C; HYPOXIA INDUCIBLE FACTOR 1ALPHA; I KAPPA B KINASE BETA; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN; SOLUBLE GLYCOPROTEIN 130 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN A;

ADIPOGENESIS; ADIPOSE TISSUE; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BIOACCUMULATION; CELL DIFFERENTIATION; CHEMOTAXIS; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FAT INTAKE; FATTY LIVER; GENE OVEREXPRESSION; GLUCOSE INTOLERANCE; HUMAN; INFLAMMATORY DISEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; MACROPHAGE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WEIGHT GAIN; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE;

ADIPOSE TISSUE; ANIMALS; CYTOKINE RECEPTOR GP130; DIET, HIGH-FAT; INSULIN RESISTANCE; INTERLEUKIN-6; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTORS, INTERLEUKIN-6; SIGNAL TRANSDUCTION;

EID: 84924415012     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.02.006     Document Type: Article

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