-
1
-
-
0034708832
-
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
-
V. Aguirre, T. Uchida, L. Yenush, R. Davis, and M.F. White The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307) J. Biol. Chem. 275 2000 9047 9054
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9047-9054
-
-
Aguirre, V.1
Uchida, T.2
Yenush, L.3
Davis, R.4
White, M.F.5
-
2
-
-
20044387026
-
IKK-beta links inflammation to obesity-induced insulin resistance
-
M.C. Arkan, A.L. Hevener, F.R. Greten, S. Maeda, Z.W. Li, J.M. Long, A. Wynshaw-Boris, G. Poli, J. Olefsky, and M. Karin IKK-beta links inflammation to obesity-induced insulin resistance Nat. Med. 11 2005 191 198
-
(2005)
Nat. Med.
, vol.11
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.W.5
Long, J.M.6
Wynshaw-Boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
-
3
-
-
0033678516
-
Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss
-
J.P. Bastard, C. Jardel, E. Bruckert, P. Blondy, J. Capeau, M. Laville, H. Vidal, and B. Hainque Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss J. Clin. Endocrinol. Metab. 85 2000 3338 3342
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 3338-3342
-
-
Bastard, J.P.1
Jardel, C.2
Bruckert, E.3
Blondy, P.4
Capeau, J.5
Laville, M.6
Vidal, H.7
Hainque, B.8
-
4
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
-
D. Cai, M. Yuan, D.F. Frantz, P.A. Melendez, L. Hansen, J. Lee, and S.E. Shoelson Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB Nat. Med. 11 2005 183 190
-
(2005)
Nat. Med.
, vol.11
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
5
-
-
33750859187
-
Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase
-
A.L. Carey, G.R. Steinberg, S.L. Macaulay, W.G. Thomas, A.G. Holmes, G. Ramm, O. Prelovsek, C. Hohnen-Behrens, M.J. Watt, and D.E. James Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase Diabetes 55 2006 2688 2697
-
(2006)
Diabetes
, vol.55
, pp. 2688-2697
-
-
Carey, A.L.1
Steinberg, G.R.2
MacAulay, S.L.3
Thomas, W.G.4
Holmes, A.G.5
Ramm, G.6
Prelovsek, O.7
Hohnen-Behrens, C.8
Watt, M.J.9
James, D.E.10
-
6
-
-
33745315308
-
Combined interleukin-6 and interleukin-1 deficiency causes obesity in young mice
-
D. Chida, T. Osaka, O. Hashimoto, and Y. Iwakura Combined interleukin-6 and interleukin-1 deficiency causes obesity in young mice Diabetes 55 2006 971 977
-
(2006)
Diabetes
, vol.55
, pp. 971-977
-
-
Chida, D.1
Osaka, T.2
Hashimoto, O.3
Iwakura, Y.4
-
7
-
-
0036899812
-
Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: A randomized, double-blind, placebo-controlled, dose-escalation trial
-
E.H. Choy, D.A. Isenberg, T. Garrood, S. Farrow, Y. Ioannou, H. Bird, N. Cheung, B. Williams, B. Hazleman, and R. Price Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial Arthritis Rheum. 46 2002 3143 3150
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 3143-3150
-
-
Choy, E.H.1
Isenberg, D.A.2
Garrood, T.3
Farrow, S.4
Ioannou, Y.5
Bird, H.6
Cheung, N.7
Williams, B.8
Hazleman, B.9
Price, R.10
-
8
-
-
41149083879
-
Tumor necrosis factor alpha mediates the lethal hepatotoxic effects of poly(I:C) in D-galactosamine-sensitized mice
-
L. Dejager, and C. Libert Tumor necrosis factor alpha mediates the lethal hepatotoxic effects of poly(I:C) in D-galactosamine-sensitized mice Cytokine 42 2008 55 61
-
(2008)
Cytokine
, vol.42
, pp. 55-61
-
-
Dejager, L.1
Libert, C.2
-
9
-
-
3042739678
-
Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: Absence of development of age-related obesity
-
G.B. Di Gregorio, L. Hensley, T. Lu, G. Ranganathan, and P.A. Kern Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity Am. J. Physiol. Endocrinol. Metab. 287 2004 E182 E187
-
(2004)
Am. J. Physiol. Endocrinol. Metab.
, vol.287
-
-
Di Gregorio, G.B.1
Hensley, L.2
Lu, T.3
Ranganathan, G.4
Kern, P.A.5
-
10
-
-
0021839186
-
A method to quantify glucose utilization in vivo in skeletal muscle and white adipose tissue of the anaesthetized rat
-
P. Ferré, A. Leturque, A.F. Burnol, L. Penicaud, and J. Girard A method to quantify glucose utilization in vivo in skeletal muscle and white adipose tissue of the anaesthetized rat Biochem. J. 228 1985 103 110
-
(1985)
Biochem. J.
, vol.228
, pp. 103-110
-
-
Ferré, P.1
Leturque, A.2
Burnol, A.F.3
Penicaud, L.4
Girard, J.5
-
11
-
-
0037324750
-
Insulin signaling is required for insulin's direct and indirect action on hepatic glucose production
-
S.J. Fisher, and C.R. Kahn Insulin signaling is required for insulin's direct and indirect action on hepatic glucose production J. Clin. Invest. 111 2003 463 468
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 463-468
-
-
Fisher, S.J.1
Kahn, C.R.2
-
12
-
-
27344433932
-
Agouti-related peptide-expressing neurons are mandatory for feeding
-
E. Gropp, M. Shanabrough, E. Borok, A.W. Xu, R. Janoschek, T. Buch, L. Plum, N. Balthasar, B. Hampel, and A. Waisman Agouti-related peptide-expressing neurons are mandatory for feeding Nat. Neurosci. 8 2005 1289 1291
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1289-1291
-
-
Gropp, E.1
Shanabrough, M.2
Borok, E.3
Xu, A.W.4
Janoschek, R.5
Buch, T.6
Plum, L.7
Balthasar, N.8
Hampel, B.9
Waisman, A.10
-
13
-
-
0042748684
-
A new microvolume technique for bioaffinity assays using two-photon excitation
-
P. Hänninen, A. Soini, N. Meltola, J. Soini, J. Soukka, and E. Soini A new microvolume technique for bioaffinity assays using two-photon excitation Nat. Biotechnol. 18 2000 548 550
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 548-550
-
-
Hänninen, P.1
Soini, A.2
Meltola, N.3
Soini, J.4
Soukka, J.5
Soini, E.6
-
14
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
J. Hirosumi, G. Tuncman, L. Chang, C.Z. Görgün, K.T. Uysal, K. Maeda, M. Karin, and G.S. Hotamisligil A central role for JNK in obesity and insulin resistance Nature 420 2002 333 336
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Görgün, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
15
-
-
51349111709
-
Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats
-
A.G. Holmes, J.L. Mesa, B.A. Neill, J. Chung, A.L. Carey, G.R. Steinberg, B.E. Kemp, R.J. Southgate, G.I. Lancaster, and C.R. Bruce Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats J. Endocrinol. 198 2008 367 374
-
(2008)
J. Endocrinol.
, vol.198
, pp. 367-374
-
-
Holmes, A.G.1
Mesa, J.L.2
Neill, B.A.3
Chung, J.4
Carey, A.L.5
Steinberg, G.R.6
Kemp, B.E.7
Southgate, R.J.8
Lancaster, G.I.9
Bruce, C.R.10
-
16
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
G.S. Hotamisligil, N.S. Shargill, and B.M. Spiegelman Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance Science 259 1993 87 91
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
17
-
-
0028031569
-
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha
-
G.S. Hotamisligil, A. Budavari, D. Murray, and B.M. Spiegelman Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha J. Clin. Invest. 94 1994 1543 1549
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 1543-1549
-
-
Hotamisligil, G.S.1
Budavari, A.2
Murray, D.3
Spiegelman, B.M.4
-
19
-
-
0031053823
-
Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance
-
G.S. Hotamisligil, P. Arner, R.L. Atkinson, and B.M. Spiegelman Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance Diabetes 46 1997 451 455
-
(1997)
Diabetes
, vol.46
, pp. 451-455
-
-
Hotamisligil, G.S.1
Arner, P.2
Atkinson, R.L.3
Spiegelman, B.M.4
-
20
-
-
33645579324
-
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production
-
H. Inoue, W. Ogawa, A. Asakawa, Y. Okamoto, A. Nishizawa, M. Matsumoto, K. Teshigawara, Y. Matsuki, E. Watanabe, and R. Hiramatsu Role of hepatic STAT3 in brain-insulin action on hepatic glucose production Cell Metab. 3 2006 267 275
-
(2006)
Cell Metab.
, vol.3
, pp. 267-275
-
-
Inoue, H.1
Ogawa, W.2
Asakawa, A.3
Okamoto, Y.4
Nishizawa, A.5
Matsumoto, M.6
Teshigawara, K.7
Matsuki, Y.8
Watanabe, E.9
Hiramatsu, R.10
-
21
-
-
0034063279
-
Hepatocyte-specific expression of Cre recombinase
-
C. Kellendonk, C. Opherk, K. Anlag, G. Schütz, and F. Tronche Hepatocyte-specific expression of Cre recombinase Genesis 26 2000 151 153
-
(2000)
Genesis
, vol.26
, pp. 151-153
-
-
Kellendonk, C.1
Opherk, C.2
Anlag, K.3
Schütz, G.4
Tronche, F.5
-
22
-
-
12144290761
-
Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo
-
H.J. Kim, T. Higashimori, S.Y. Park, H. Choi, J. Dong, Y.J. Kim, H.L. Noh, Y.R. Cho, G. Cline, Y.B. Kim, and J.K. Kim Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo Diabetes 53 2004 1060 1067
-
(2004)
Diabetes
, vol.53
, pp. 1060-1067
-
-
Kim, H.J.1
Higashimori, T.2
Park, S.Y.3
Choi, H.4
Dong, J.5
Kim, Y.J.6
Noh, H.L.7
Cho, Y.R.8
Cline, G.9
Kim, Y.B.10
Kim, J.K.11
-
23
-
-
70349484212
-
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance in diet-induced obesity
-
A. Kleinridders, D. Schenten, A.C. Konner, B.F. Belgardt, J. Mauer, T. Okamura, F.T. Wunderlich, R. Medzhitov, and J.C. Bruning MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance in diet-induced obesity Cell Metab. 10 2009 249 259
-
(2009)
Cell Metab.
, vol.10
, pp. 249-259
-
-
Kleinridders, A.1
Schenten, D.2
Konner, A.C.3
Belgardt, B.F.4
Mauer, J.5
Okamura, T.6
Wunderlich, F.T.7
Medzhitov, R.8
Bruning, J.C.9
-
24
-
-
0242268894
-
Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice
-
P.J. Klover, T.A. Zimmers, L.G. Koniaris, and R.A. Mooney Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice Diabetes 52 2003 2784 2789
-
(2003)
Diabetes
, vol.52
, pp. 2784-2789
-
-
Klover, P.J.1
Zimmers, T.A.2
Koniaris, L.G.3
Mooney, R.A.4
-
25
-
-
34249651956
-
Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production
-
A.C. Könner, R. Janoschek, L. Plum, S.D. Jordan, E. Rother, X. Ma, C. Xu, P. Enriori, B. Hampel, and G.S. Barsh Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production Cell Metab. 5 2007 438 449
-
(2007)
Cell Metab.
, vol.5
, pp. 438-449
-
-
Könner, A.C.1
Janoschek, R.2
Plum, L.3
Jordan, S.D.4
Rother, E.5
Ma, X.6
Xu, C.7
Enriori, P.8
Hampel, B.9
Barsh, G.S.10
-
26
-
-
0016209124
-
The preparation of, and studies on, free cell suspensions from mouse pancreatic islets
-
A. Lernmark The preparation of, and studies on, free cell suspensions from mouse pancreatic islets Diabetologia 10 1974 431 438
-
(1974)
Diabetologia
, vol.10
, pp. 431-438
-
-
Lernmark, A.1
-
27
-
-
0028965563
-
Soluble interleukin 6 receptor is biologically active in vivo
-
A. Mackiewicz, M. Wiznerowicz, E. Roeb, A. Karczewska, J. Nowak, P.C. Heinrich, and S. Rose-John Soluble interleukin 6 receptor is biologically active in vivo Cytokine 7 1995 142 149
-
(1995)
Cytokine
, vol.7
, pp. 142-149
-
-
MacKiewicz, A.1
Wiznerowicz, M.2
Roeb, E.3
Karczewska, A.4
Nowak, J.5
Heinrich, P.C.6
Rose-John, S.7
-
28
-
-
2642558925
-
Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: A multicenter, double-blind, placebo-controlled trial
-
N. Nishimoto, K. Yoshizaki, N. Miyasaka, K. Yamamoto, S. Kawai, T. Takeuchi, J. Hashimoto, J. Azuma, and T. Kishimoto Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial Arthritis Rheum. 50 2004 1761 1769
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 1761-1769
-
-
Nishimoto, N.1
Yoshizaki, K.2
Miyasaka, N.3
Yamamoto, K.4
Kawai, S.5
Takeuchi, T.6
Hashimoto, J.7
Azuma, J.8
Kishimoto, T.9
-
29
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
S. Nishimura, I. Manabe, M. Nagasaki, K. Eto, H. Yamashita, M. Ohsugi, M. Otsu, K. Hara, K. Ueki, and S. Sugiura CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity Nat. Med. 15 2009 914 920
-
(2009)
Nat. Med.
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Eto, K.4
Yamashita, H.5
Ohsugi, M.6
Otsu, M.7
Hara, K.8
Ueki, K.9
Sugiura, S.10
-
30
-
-
4544223633
-
Serum concentrations of nitric oxide, tumor necrosis factor (TNF)-alpha and TNF soluble receptors in women with overweight and obesity
-
M. Olszanecka-Glinianowicz, B. Zahorska-Markiewicz, J. Janowska, and A. Zurakowski Serum concentrations of nitric oxide, tumor necrosis factor (TNF)-alpha and TNF soluble receptors in women with overweight and obesity Metabolism 53 2004 1268 1273
-
(2004)
Metabolism
, vol.53
, pp. 1268-1273
-
-
Olszanecka-Glinianowicz, M.1
Zahorska-Markiewicz, B.2
Janowska, J.3
Zurakowski, A.4
-
31
-
-
33846883060
-
Point: Interleukin-6 does have a beneficial role in insulin sensitivity and glucose homeostasis
-
B.K. Pedersen, and M.A. Febbraio Point: Interleukin-6 does have a beneficial role in insulin sensitivity and glucose homeostasis J. Appl. Physiol. 102 2007 814 816
-
(2007)
J. Appl. Physiol.
, vol.102
, pp. 814-816
-
-
Pedersen, B.K.1
Febbraio, M.A.2
-
32
-
-
2942702298
-
The metabolic role of IL-6 produced during exercise: Is IL-6 an exercise factor?
-
B.K. Pedersen, A. Steensberg, C. Fischer, C. Keller, P. Keller, P. Plomgaard, E. Wolsk-Petersen, and M. Febbraio The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor? Proc. Nutr. Soc. 63 2004 263 267
-
(2004)
Proc. Nutr. Soc.
, vol.63
, pp. 263-267
-
-
Pedersen, B.K.1
Steensberg, A.2
Fischer, C.3
Keller, C.4
Keller, P.5
Plomgaard, P.6
Wolsk-Petersen, E.7
Febbraio, M.8
-
33
-
-
0642364997
-
Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise
-
M. Penkowa, C. Keller, P. Keller, S. Jauffred, and B.K. Pedersen Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise FASEB J. 17 2003 2166 2168
-
(2003)
FASEB J.
, vol.17
, pp. 2166-2168
-
-
Penkowa, M.1
Keller, C.2
Keller, P.3
Jauffred, S.4
Pedersen, B.K.5
-
34
-
-
25844456730
-
Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation
-
P. Plomgaard, K. Bouzakri, R. Krogh-Madsen, B. Mittendorfer, J.R. Zierath, and B.K. Pedersen Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation Diabetes 54 2005 2939 2945
-
(2005)
Diabetes
, vol.54
, pp. 2939-2945
-
-
Plomgaard, P.1
Bouzakri, K.2
Krogh-Madsen, R.3
Mittendorfer, B.4
Zierath, J.R.5
Pedersen, B.K.6
-
35
-
-
33745838578
-
Central insulin action in energy and glucose homeostasis
-
L. Plum, B.F. Belgardt, and J.C. Brüning Central insulin action in energy and glucose homeostasis J. Clin. Invest. 116 2006 1761 1766
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1761-1766
-
-
Plum, L.1
Belgardt, B.F.2
Brüning, J.C.3
-
36
-
-
0034041160
-
High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP
-
C.I. Rodríguez, F. Buchholz, J. Galloway, R. Sequerra, J. Kasper, R. Ayala, A.F. Stewart, and S.M. Dymecki High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP Nat. Genet. 25 2000 139 140
-
(2000)
Nat. Genet.
, vol.25
, pp. 139-140
-
-
Rodríguez, C.I.1
Buchholz, F.2
Galloway, J.3
Sequerra, R.4
Kasper, J.5
Ayala, R.6
Stewart, A.F.7
Dymecki, S.M.8
-
37
-
-
57349101675
-
A stress signaling pathway in adipose tissue regulates hepatic insulin resistance
-
G. Sabio, M. Das, A. Mora, Z. Zhang, J.Y. Jun, H.J. Ko, T. Barrett, J.K. Kim, and R.J. Davis A stress signaling pathway in adipose tissue regulates hepatic insulin resistance Science 322 2008 1539 1543
-
(2008)
Science
, vol.322
, pp. 1539-1543
-
-
Sabio, G.1
Das, M.2
Mora, A.3
Zhang, Z.4
Jun, J.Y.5
Ko, H.J.6
Barrett, T.7
Kim, J.K.8
Davis, R.J.9
-
38
-
-
77949266016
-
Human IL6 enhances leptin action in mice
-
M. Sadagurski, L. Norquay, J. Farhang, K. D'Aquino, K. Copps, and M.F. White Human IL6 enhances leptin action in mice Diabetologia 53 2010 525 535
-
(2010)
Diabetologia
, vol.53
, pp. 525-535
-
-
Sadagurski, M.1
Norquay, L.2
Farhang, J.3
D'Aquino, K.4
Copps, K.5
White, M.F.6
-
39
-
-
0025685395
-
Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism
-
C. Southern, D. Schulster, and I.C. Green Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism FEBS Lett. 276 1990 42 44
-
(1990)
FEBS Lett.
, vol.276
, pp. 42-44
-
-
Southern, C.1
Schulster, D.2
Green, I.C.3
-
40
-
-
2942628012
-
Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms
-
K. Ueki, T. Kondo, and C.R. Kahn Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms Mol. Cell. Biol. 24 2004 5434 5446
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5434-5446
-
-
Ueki, K.1
Kondo, T.2
Kahn, C.R.3
-
41
-
-
0030009240
-
Kupffer cell depletion by liposome-delivered drugs: Comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid
-
N. Van Rooijen, and A. Sanders Kupffer cell depletion by liposome-delivered drugs: comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid Hepatology 23 1996 1239 1243
-
(1996)
Hepatology
, vol.23
, pp. 1239-1243
-
-
Van Rooijen, N.1
Sanders, A.2
-
42
-
-
0036152683
-
Interleukin-6-deficient mice develop mature-onset obesity
-
V. Wallenius, K. Wallenius, B. Ahrén, M. Rudling, H. Carlsten, S.L. Dickson, C. Ohlsson, and J.O. Jansson Interleukin-6-deficient mice develop mature-onset obesity Nat. Med. 8 2002 75 79
-
(2002)
Nat. Med.
, vol.8
, pp. 75-79
-
-
Wallenius, V.1
Wallenius, K.2
Ahrén, B.3
Rudling, M.4
Carlsten, H.5
Dickson, S.L.6
Ohlsson, C.7
Jansson, J.O.8
-
43
-
-
0032518415
-
IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses
-
Z. Xing, J. Gauldie, G. Cox, H. Baumann, M. Jordana, X.F. Lei, and M.K. Achong IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses J. Clin. Invest. 101 1998 311 320
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 311-320
-
-
Xing, Z.1
Gauldie, J.2
Cox, G.3
Baumann, H.4
Jordana, M.5
Lei, X.F.6
Achong, M.K.7
-
44
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
H. Xu, G.T. Barnes, Q. Yang, G. Tan, D. Yang, C.J. Chou, J. Sole, A. Nichols, J.S. Ross, L.A. Tartaglia, and H. Chen Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance J. Clin. Invest. 112 2003 1821 1830
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
45
-
-
65549128076
-
Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression
-
D.Y. Yuen, R.M. Dwyer, V.B. Matthews, L. Zhang, B.G. Drew, B. Neill, B.A. Kingwell, M.G. Clark, S. Rattigan, and M.A. Febbraio Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression Diabetes 58 2009 1086 1095
-
(2009)
Diabetes
, vol.58
, pp. 1086-1095
-
-
Yuen, D.Y.1
Dwyer, R.M.2
Matthews, V.B.3
Zhang, L.4
Drew, B.G.5
Neill, B.6
Kingwell, B.A.7
Clark, M.G.8
Rattigan, S.9
Febbraio, M.A.10
-
46
-
-
0029417129
-
TNF-alpha inhibits glucose-induced insulin secretion in a pancreatic beta-cell line (INS-1)
-
S. Zhang, and K.H. Kim TNF-alpha inhibits glucose-induced insulin secretion in a pancreatic beta-cell line (INS-1) FEBS Lett. 377 1995 237 239
-
(1995)
FEBS Lett.
, vol.377
, pp. 237-239
-
-
Zhang, S.1
Kim, K.H.2
-
47
-
-
52949096557
-
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
-
X. Zhang, G. Zhang, H. Zhang, M. Karin, H. Bai, and D. Cai Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity Cell 135 2008 61 73
-
(2008)
Cell
, vol.135
, pp. 61-73
-
-
Zhang, X.1
Zhang, G.2
Zhang, H.3
Karin, M.4
Bai, H.5
Cai, D.6
|