Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance

Diabetologia

Volumn 53, Issue 11, 2010, Pages 2431-2441

  Matthews, V B ^a   Allen, T L ^a   Risis, S ^a   Chan, M H S ^a   Henstridge, D C ^a   Watson, N ^a   Zaffino, L A ^a   Babb, J R ^a   Boon, J ^b   Meikle, P J ^a   Jowett, J B ^a   Watt, M J ^b   Jansson, J O ^c   Bruce, C R ^a   Febbraio, M A ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Cytokines; Fatty liver; Obesity; Signal transduction; Type 2 diabetes

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; INTERLEUKIN 6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHROPOMETRIC PARAMETERS; ARTICLE; CITRIC ACID CYCLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; FAT MASS; FATTY LIVER; GENE DELETION; HEPATITIS; INSULIN RESISTANCE; LIPID DIET; LIPID STORAGE; LIVER INJURY; LIVER PARENCHYMA; MALE; MICROARRAY ANALYSIS; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; WEIGHT GAIN;

ADIPOCYTES; ADIPOSITY; ANIMALS; BODY COMPOSITION; CALORIMETRY, INDIRECT; CELL SIZE; DIGLYCERIDES; FATTY LIVER; FEMALE; INFLAMMATION; INSULIN RESISTANCE; INTERLEUKIN-6; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY; TRIGLYCERIDES;

EID: 77957661299     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1865-y     Document Type: Article

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