Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activator

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 52, 2014, Pages E5651-E5660

  Shi, Qing ^a   Li, Shuang ^a   Li, Shuangxi ^a,b   Jiang, Alice ^a   Chen, Yongbin ^c   Jiang, Jin ^a,d  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b EAST CHINA NORMAL UNIVERSITY   (China)

^c KUNMING INSTITUTE OF ZOOLOGY   (China)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Ci; CK1; Gli; Hedgehog; SPOP

Indexed keywords

CASEIN KINASE I; CUBITUS INTERRUPTUS GLIOMA ASSOCIATED ONCOGENE HOMOLOG TRANSCRIPTION FACTOR; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CI PROTEIN, DROSOPHILA; COS PROTEIN, DROSOPHILA; CULLIN; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; GFT PROTEIN, DROSOPHILA; GLI PROTEIN; HEDGEHOG PROTEIN, DROSOPHILA; KINESIN; ONCOPROTEIN; REPRESSOR PROTEIN; SUFU PROTEIN, DROSOPHILA; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; ENZYME STABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; DROSOPHILA MELANOGASTER; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN TERTIARY STRUCTURE;

ERINACEIDAE;

ANIMALS; CASEIN KINASE I; CELL LINE; CULLIN PROTEINS; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HEDGEHOG PROTEINS; KINESIN; ONCOGENE PROTEINS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 84924302028     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1416652111     Document Type: Article

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