메뉴 건너뛰기




Volumn 126, Issue 19, 1999, Pages 4331-4339

Proteolysis of cubitus interruptus in Drosophila requires phosphorylation by protein kinase A

Author keywords

Cubitus interruptus; Drosophila; Hedgehog; Protein kinase A; Proteolysis

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA BINDING PROTEIN; TRANSACTIVATOR PROTEIN;

EID: 0032756914     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (140)

References (32)
  • 1
    • 0029858774 scopus 로고    scopus 로고
    • Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the Cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins
    • Alexandre, C., Jacinto, A. and Ingham, P. W. (1996). Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the Cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. Genes Dev. 10, 2003-2013.
    • (1996) Genes Dev. , vol.10 , pp. 2003-2013
    • Alexandre, C.1    Jacinto, A.2    Ingham, P.W.3
  • 2
    • 0031587830 scopus 로고    scopus 로고
    • Proteolysis that is inhibited by Hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor
    • Aza-Blanc, P., Ramírez-Weber, F.-A., Laget, M.-P., Schwartz, C. and Kornberg, T. B. (1997). Proteolysis that is inhibited by Hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor. Cell 1043-1053.
    • (1997) Cell , pp. 1043-1053
    • Aza-Blanc, P.1    Ramírez-Weber, F.-A.2    Laget, M.-P.3    Schwartz, C.4    Kornberg, T.B.5
  • 3
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 4
    • 0027404264 scopus 로고
    • Distinct TFIID complexes mediate the effect of different transcriptional activators
    • Brou, C., Chaudhary, S., Davidson, I., Lutz, Y., Wu, J., Egly, J.-M., Tora, L. and Chambon, P. (1993). Distinct TFIID complexes mediate the effect of different transcriptional activators. EMBO J. 12, 489-499.
    • (1993) EMBO J. , vol.12 , pp. 489-499
    • Brou, C.1    Chaudhary, S.2    Davidson, I.3    Lutz, Y.4    Wu, J.5    Egly, J.-M.6    Tora, L.7    Chambon, P.8
  • 5
    • 0032478107 scopus 로고    scopus 로고
    • Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus
    • Chen, V., Gallaher, N., Goodman, R. H. and Smolik, S. M. (1998). Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus. Proc. Natl. Acad. Sci. USA 95, 2349-2354.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2349-2354
    • Chen, V.1    Gallaher, N.2    Goodman, R.H.3    Smolik, S.M.4
  • 7
    • 0029896212 scopus 로고    scopus 로고
    • Sending and receiving the hedgehog signal: Control by the Drosophila Gli protein cubitus interruptus
    • Domínguez, M., Brunner, M., Hafen, E. and Basler, K. (1996). Sending and receiving the hedgehog signal: control by the Drosophila Gli protein cubitus interruptus. Science 272, 1621-1625.
    • (1996) Science , vol.272 , pp. 1621-1625
    • Domínguez, M.1    Brunner, M.2    Hafen, E.3    Basler, K.4
  • 8
    • 0029041177 scopus 로고
    • Long-range sclerotome induction by Sonic hedgehog: Direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway
    • Fan, C.-M., Porter, J. A., Chiang, C., Chang, D. T., Beachy, P. A. and Tessier-Lavigne, M. (1995). Long-range sclerotome induction by Sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway. Cell 81, 457-465.
    • (1995) Cell , vol.81 , pp. 457-465
    • Fan, C.-M.1    Porter, J.A.2    Chiang, C.3    Chang, D.T.4    Beachy, P.A.5    Tessier-Lavigne, M.6
  • 9
    • 0029879687 scopus 로고    scopus 로고
    • Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo
    • Hammerschmidt, M., Bitgood, M. J. and McMahon, A. P. (1996). Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes Dev. 10, 647658.
    • (1996) Genes Dev. , vol.10 , pp. 647658
    • Hammerschmidt, M.1    Bitgood, M.J.2    McMahon, A.P.3
  • 10
    • 0031051385 scopus 로고    scopus 로고
    • The world according to hedgehog
    • Hammerschmidt, M., Brook, A. and McMahon, A. P. (1997). The world according to hedgehog. TIG 13, 14-21.
    • (1997) TIG , vol.13 , pp. 14-21
    • Hammerschmidt, M.1    Brook, A.2    McMahon, A.P.3
  • 11
    • 0031040287 scopus 로고    scopus 로고
    • Drosophila cubitus interruptus forms a negative feedback loop with patched and regulates expression of Hedgehog target genes
    • Hepker, J., Wang, Q.-T., Motzny, C. K., Holmgren, R. and Orenic, T. V. (1997). Drosophila cubitus interruptus forms a negative feedback loop with patched and regulates expression of Hedgehog target genes. Develpment 124, 549-558.
    • (1997) Develpment , vol.124 , pp. 549-558
    • Hepker, J.1    Wang, Q.-T.2    Motzny, C.K.3    Holmgren, R.4    Orenic, T.V.5
  • 12
    • 0032126734 scopus 로고    scopus 로고
    • Transducing Hedgehog: The story so far
    • Ingham, P. W. (1998). Transducing Hedgehog: the story so far. EMBO J. 17, 3505-3511.
    • (1998) EMBO J. , vol.17 , pp. 3505-3511
    • Ingham, P.W.1
  • 13
    • 0032576777 scopus 로고    scopus 로고
    • Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb
    • Jiang, J. and Strahl, G. (1998). Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature 391, 493-496.
    • (1998) Nature , vol.391 , pp. 493-496
    • Jiang, J.1    Strahl, G.2
  • 14
    • 0029417009 scopus 로고
    • patched overexpression alters wing disc size and pattern: Transcriptional and post-transcriptional effects on hedgehog targets
    • Johnson, R. L., Grenier, J. K. and Scott, M. P. (1995). patched overexpression alters wing disc size and pattern: transcriptional and post-transcriptional effects on hedgehog targets. Development 121, 4161-4170.
    • (1995) Development , vol.121 , pp. 4161-4170
    • Johnson, R.L.1    Grenier, J.K.2    Scott, M.P.3
  • 15
    • 0031436999 scopus 로고    scopus 로고
    • Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase
    • Krishnan, V., Pereira, F. A., Qiu, Y., Chen, C. H., Beachy, P. A., Tsai, S. Y. and Tsai, M. J. (1997). Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase. Science 278, 1947-1950.
    • (1997) Science , vol.278 , pp. 1947-1950
    • Krishnan, V.1    Pereira, F.A.2    Qiu, Y.3    Chen, C.H.4    Beachy, P.A.5    Tsai, S.Y.6    Tsai, M.J.7
  • 16
    • 0028897883 scopus 로고
    • Function of protein kinase A in Hedgehog signal transduction and Drosophila imaginal disc development
    • Li, W., Ohlmeyer, J. T., Lane, M. E. and Kalderon, D. (1995). Function of protein kinase A in Hedgehog signal transduction and Drosophila imaginal disc development. Cell 80, 553-562.
    • (1995) Cell , vol.80 , pp. 553-562
    • Li, W.1    Ohlmeyer, J.T.2    Lane, M.E.3    Kalderon, D.4
  • 17
    • 0033106149 scopus 로고    scopus 로고
    • A ubiquitin ligase complex essential for the NF-κB, Wnt/Wingless, and Hedgehog signaling pathways
    • Maniatis, T. (1999). A ubiquitin ligase complex essential for the NF-κB, Wnt/Wingless, and Hedgehog signaling pathways. Genes Dev. 13, 505-510.
    • (1999) Genes Dev. , vol.13 , pp. 505-510
    • Maniatis, T.1
  • 18
    • 0033582908 scopus 로고    scopus 로고
    • Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus
    • Méthot, N. and Basler, K. (1999). Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. Cell 96, 819-831.
    • (1999) Cell , vol.96 , pp. 819-831
    • Méthot, N.1    Basler, K.2
  • 19
    • 0032492995 scopus 로고    scopus 로고
    • Supressor of fused links Fused and Cubitus interruptus on the Hedgehog signalling pathway
    • Monnier, V., Dussillol, F., Alves, G., Lamour-Isnard, C. and Plessis, A. (1998). Supressor of fused links Fused and Cubitus interruptus on the Hedgehog signalling pathway. Current Biol. 8, 583-586.
    • (1998) Current Biol. , vol.8 , pp. 583-586
    • Monnier, V.1    Dussillol, F.2    Alves, G.3    Lamour-Isnard, C.4    Plessis, A.5
  • 20
    • 0029126148 scopus 로고
    • The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways
    • Motzny, C. K. and Holmgren, R. (1995). The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways. Mech. Dev. 52, 137-150.
    • (1995) Mech. Dev. , vol.52 , pp. 137-150
    • Motzny, C.K.1    Holmgren, R.2
  • 21
    • 0030984470 scopus 로고    scopus 로고
    • Dual pathways for induction of wingless expression by protein kinase A and Hedgehog in Drosophila embryos
    • Ohlmeyer, J. T. and Kalderon, D. (1997). Dual pathways for induction of wingless expression by protein kinase A and Hedgehog in Drosophila embryos. Genes Dev. 11, 2250-2258.
    • (1997) Genes Dev. , vol.11 , pp. 2250-2258
    • Ohlmeyer, J.T.1    Kalderon, D.2
  • 22
    • 0032585515 scopus 로고    scopus 로고
    • Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator
    • Ohlmeyer, J. T. and Kalderon, D. (1998). Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator. Nature 396, 749-753.
    • (1998) Nature , vol.396 , pp. 749-753
    • Ohlmeyer, J.T.1    Kalderon, D.2
  • 23
    • 0025331133 scopus 로고
    • Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila
    • Orenic, T. V., Slusarski, D. C., Kroll, K. L. and Holmgren, R. A. (1990). Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila. Genes Dev. 4, 1053-1067.
    • (1990) Genes Dev. , vol.4 , pp. 1053-1067
    • Orenic, T.V.1    Slusarski, D.C.2    Kroll, K.L.3    Holmgren, R.A.4
  • 24
    • 0030838880 scopus 로고    scopus 로고
    • Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein Costal2
    • Robbins, D. J., Nybakken, K. E., Kobayashi, R., Sisson, J. C., Bishop, J. M. and Therond, P. P. (1997). Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein Costal2. Cell 90, 225-234.
    • (1997) Cell , vol.90 , pp. 225-234
    • Robbins, D.J.1    Nybakken, K.E.2    Kobayashi, R.3    Sisson, J.C.4    Bishop, J.M.5    Therond, P.P.6
  • 25
    • 0032808138 scopus 로고    scopus 로고
    • Gli proteins encode context-dependent positive and negative functions: Implications for development and disease
    • Ruiz i Altaba, A. (1999). Gli proteins encode context-dependent positive and negative functions: implications for development and disease. Development 126, 3205-3216.
    • (1999) Development , vol.126 , pp. 3205-3216
    • Ruiz I Altaba, A.1
  • 26
    • 0025172883 scopus 로고
    • GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity
    • Ruppert, J. M., Vogelstein, B., Arheden, K. and Kinzler, K. W. (1990). GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity. Mol. Cell. Biol. 10, 5408-5414.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5408-5414
    • Ruppert, J.M.1    Vogelstein, B.2    Arheden, K.3    Kinzler, K.W.4
  • 27
    • 0030754171 scopus 로고    scopus 로고
    • Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway
    • Sisson, J. C., Ho, K. S., Suyama, K. and Scott, M. P. (1997). Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway. Cell 90, 235-245.
    • (1997) Cell , vol.90 , pp. 235-245
    • Sisson, J.C.1    Ho, K.S.2    Suyama, K.3    Scott, M.P.4
  • 28
    • 0028809104 scopus 로고
    • Mutations that alter the timing and pattern of cubitus interruptus gene expression in Drosophila melanogaster
    • Slusarski, D. C., Motzny, C. K. and Holmgren, R. (1995). Mutations that alter the timing and pattern of cubitus interruptus gene expression in Drosophila melanogaster. Genetics 139, 229-240.
    • (1995) Genetics , vol.139 , pp. 229-240
    • Slusarski, D.C.1    Motzny, C.K.2    Holmgren, R.3
  • 29
    • 0031671351 scopus 로고    scopus 로고
    • slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development
    • Theodosiou, N. A., Zhang, S., Wang, W. Y. and Xu, T. (1998). slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development. Development 125, 3411-3416.
    • (1998) Development , vol.125 , pp. 3411-3416
    • Theodosiou, N.A.1    Zhang, S.2    Wang, W.Y.3    Xu, T.4
  • 30
    • 0029961659 scopus 로고    scopus 로고
    • Phosphorylation of the Fused protein kinase in response to signaling from hedgehog. Prof
    • Thérond, P. P., Knight, J. D., Kornberg, T. and Bishop, J. M. (1996). Phosphorylation of the Fused protein kinase in response to signaling from hedgehog. Prof. Natl. Acad. Sci. USA 93, 4224-4228.
    • (1996) Natl. Acad. Sci. USA , vol.93 , pp. 4224-4228
    • Thérond, P.P.1    Knight, J.D.2    Kornberg, T.3    Bishop, J.M.4
  • 31
    • 0028557441 scopus 로고
    • Multiple pathway signal transduction by the cAMP-dependent protein kinase
    • Walsh, D. A. and Van Patten, S. M. (1994). Multiple pathway signal transduction by the cAMP-dependent protein kinase. FASEB J. 8, 1227-1236.
    • (1994) FASEB J. , vol.8 , pp. 1227-1236
    • Walsh, D.A.1    Van Patten, S.M.2
  • 32
    • 0029114331 scopus 로고
    • Evidence for engrailed-independent wingless autoregulation in Drosophila
    • Yoffe, K. B., Manoukian, A. S., Wilder, E. S., Brand, A. H. and Perrimon, N. (1995). Evidence for engrailed-independent wingless autoregulation in Drosophila. Dev. Biol. 170, 636-650.
    • (1995) Dev. Biol. , vol.170 , pp. 636-650
    • Yoffe, K.B.1    Manoukian, A.S.2    Wilder, E.S.3    Brand, A.H.4    Perrimon, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.