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Volumn 49, Issue 5, 2015, Pages 2625-2638

The challenge presented by progestins in ecotoxicological research: A critical review

Author keywords

[No Author keywords available]

Indexed keywords

BIOACCUMULATION; CELL PROLIFERATION; EFFLUENTS; FISH; SEWAGE; STEROID HORMONES;

EID: 84924070811     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es5051343     Document Type: Review
Times cited : (140)

References (159)
  • 1
    • 0031844641 scopus 로고    scopus 로고
    • Endocrine disruption in wildlife: A critical review of the evidence
    • Tyler, C. R.; Jobling, S.; Sumpter, J. P. Endocrine disruption in wildlife: A critical review of the evidence Crit. Rev. Toxicol. 1998, 28 (4) 319-361
    • (1998) Crit. Rev. Toxicol. , vol.28 , Issue.4 , pp. 319-361
    • Tyler, C.R.1    Jobling, S.2    Sumpter, J.P.3
  • 2
    • 33746730199 scopus 로고    scopus 로고
    • Screening and testing for endocrine disruption in fish-Biomarkers as "signposts," not "traffic lights," in risk assessment
    • S-1
    • Hutchinson, T. H.; Ankley, G. T.; Segner, H.; Tyler, C. R. Screening and testing for endocrine disruption in fish-Biomarkers as "signposts," not "traffic lights," in risk assessment Environ. Health Perspect. 2006, 114 (S-1) 106-114
    • (2006) Environ. Health Perspect. , vol.114 , pp. 106-114
    • Hutchinson, T.H.1    Ankley, G.T.2    Segner, H.3    Tyler, C.R.4
  • 3
    • 20744448987 scopus 로고    scopus 로고
    • Lessons from endocrine disruption and their application to other issues concerning trace organics in the aquatic environment
    • Sumpter, J. P.; Johnson, A. C. Lessons from endocrine disruption and their application to other issues concerning trace organics in the aquatic environment Environ. Sci. Technol. 2005, 39 (12) 4321-4332
    • (2005) Environ. Sci. Technol. , vol.39 , Issue.12 , pp. 4321-4332
    • Sumpter, J.P.1    Johnson, A.C.2
  • 8
    • 84860462209 scopus 로고    scopus 로고
    • Progestins and antiprogestins affect gene expression in early development in zebrafish (Danio rerio) at environmental concentrations
    • Zucchi, S.; Castiglioni, S.; Fent, K. Progestins and antiprogestins affect gene expression in early development in zebrafish (Danio rerio) at environmental concentrations Environ. Sci. Technol. 2012, 46 (9) 5183-5192
    • (2012) Environ. Sci. Technol. , vol.46 , Issue.9 , pp. 5183-5192
    • Zucchi, S.1    Castiglioni, S.2    Fent, K.3
  • 9
    • 84874029024 scopus 로고    scopus 로고
    • Several synthetic progestins with different potencies adversely affect reproduction of fish
    • Runnalls, T. J.; Beresford, N.; Losty, E.; Scott, A. P.; Sumpter, J. P. Several synthetic progestins with different potencies adversely affect reproduction of fish Environ. Sci. Technol. 2013, 47 (4) 2077-2084
    • (2013) Environ. Sci. Technol. , vol.47 , Issue.4 , pp. 2077-2084
    • Runnalls, T.J.1    Beresford, N.2    Losty, E.3    Scott, A.P.4    Sumpter, J.P.5
  • 10
    • 84906791625 scopus 로고    scopus 로고
    • Sources, concentrations, and exposure effects of environmental gestagens on fish and other aquatic wildlife, with an emphasis on reproduction
    • SI
    • Orlando, E. F.; Ellestad, L. E. Sources, concentrations, and exposure effects of environmental gestagens on fish and other aquatic wildlife, with an emphasis on reproduction Gen. Comp. Endocrinol. 2014, 203 (SI) 241-249
    • (2014) Gen. Comp. Endocrinol. , vol.203 , pp. 241-249
    • Orlando, E.F.1    Ellestad, L.E.2
  • 11
    • 84886892832 scopus 로고    scopus 로고
    • Hans Herloff Inhoffen in his times (1906-1992)
    • Quinkert, G. Hans Herloff Inhoffen in his times (1906-1992) Eur. J. Org. Chem. 2004, 2004 (17) 3727-3748
    • (2004) Eur. J. Org. Chem. , vol.2004 , Issue.17 , pp. 3727-3748
    • Quinkert, G.1
  • 12
    • 0036549576 scopus 로고    scopus 로고
    • Women's trials: The approval of the first oral contraceptive pill in the United States and Great Britain
    • Junod, S. W.; Marks, L. Women's trials: The approval of the first oral contraceptive pill in the United States and Great Britain J. Hist. Med. Allied Sci. 2002, 57 (2) 117-160
    • (2002) J. Hist. Med. Allied Sci. , vol.57 , Issue.2 , pp. 117-160
    • Junod, S.W.1    Marks, L.2
  • 13
    • 0026708878 scopus 로고
    • The role of progestins in hormone replacement therapy
    • Lobo, R. A. The role of progestins in hormone replacement therapy Am. J. Obstet. Gynecol. 1992, 166 (6, Part 2) 1997-2004
    • (1992) Am. J. Obstet. Gynecol. , vol.166 , Issue.6 , pp. 1997-2004
    • Lobo, R.A.1
  • 14
    • 0020541155 scopus 로고
    • Role of estrogens and progesterone in the etiology and prevention of endometrial cancer: Review
    • Gambrell, R.; Bagnell, C.; Greenblatt, R. Role of estrogens and progesterone in the etiology and prevention of endometrial cancer: Review Am. J. Obstet. Gynecol. 1983, 146 (6) 696-707
    • (1983) Am. J. Obstet. Gynecol. , vol.146 , Issue.6 , pp. 696-707
    • Gambrell, R.1    Bagnell, C.2    Greenblatt, R.3
  • 15
    • 0029849190 scopus 로고    scopus 로고
    • Management of abnormal uterine bleeding
    • Chuong, C. J.; Brenner, P. F. Management of abnormal uterine bleeding Am. J. Obstet. Gynecol. 1996, 175 (3, Part 2) 787-792
    • (1996) Am. J. Obstet. Gynecol. , vol.175 , Issue.3 , pp. 787-792
    • Chuong, C.J.1    Brenner, P.F.2
  • 16
    • 0029893711 scopus 로고    scopus 로고
    • Placebo-controlled trial of medroxy-Progesterone acetate in gastrointestinal malignancies and cachexia
    • Kornek, G. V.; Schenk, T.; Ludwig, H.; Hejna, M.; Scheithauer, W. Placebo-controlled trial of medroxy-Progesterone acetate in gastrointestinal malignancies and cachexia Oncol. Res. Treat. 1996, 19 (2) 164-168
    • (1996) Oncol. Res. Treat. , vol.19 , Issue.2 , pp. 164-168
    • Kornek, G.V.1    Schenk, T.2    Ludwig, H.3    Hejna, M.4    Scheithauer, W.5
  • 17
    • 74449083832 scopus 로고    scopus 로고
    • Progestagens for human use, exposure and hazard assessment for the aquatic environment
    • Besse, J.-P.; Garric, J. Progestagens for human use, exposure and hazard assessment for the aquatic environment Environ. Pollut. 2009, 157 (12) 3485-3494
    • (2009) Environ. Pollut. , vol.157 , Issue.12 , pp. 3485-3494
    • Besse, J.-P.1    Garric, J.2
  • 18
    • 78650285954 scopus 로고    scopus 로고
    • Pharmaceuticals in the aquatic environment: Steroids and anti-steroids as high priorities for research
    • Runnalls, T. J.; Margiotta-Casaluci, L.; Kugathas, S.; Sumpter, J. P. Pharmaceuticals in the aquatic environment: steroids and anti-steroids as high priorities for research Hum. Ecol. Risk Assess. 2010, 16 (6) 1318-1338
    • (2010) Hum. Ecol. Risk Assess. , vol.16 , Issue.6 , pp. 1318-1338
    • Runnalls, T.J.1    Margiotta-Casaluci, L.2    Kugathas, S.3    Sumpter, J.P.4
  • 19
    • 84924051225 scopus 로고    scopus 로고
    • (access date: Feb. 15, 2014).
    • State Institute for Drug Control, http://www.sukl.eu/modules/medication/. (access date: Feb. 15, 2014).
    • State Institute for Drug Control
  • 20
    • 80054768321 scopus 로고    scopus 로고
    • Occurrence, fate and removal of synthetic oral contraceptives (SOCs) in the natural environment: A review
    • Liu, Z.; Ogejo, J. A.; Pruden, A.; Knowlton, K. F. Occurrence, fate and removal of synthetic oral contraceptives (SOCs) in the natural environment: A review Sci. Total Environ. 2011, 409 (24) 5149-5161
    • (2011) Sci. Total Environ. , vol.409 , Issue.24 , pp. 5149-5161
    • Liu, Z.1    Ogejo, J.A.2    Pruden, A.3    Knowlton, K.F.4
  • 22
    • 0025239785 scopus 로고
    • Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • Kastner, P.; Krust, A.; Turcotte, B.; Stropp, U.; Tora, L.; Gronemeyer, H.; Chambon, P. Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B EMBO J. 1990, 9 (5) 1603-1614
    • (1990) EMBO J. , vol.9 , Issue.5 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3    Stropp, U.4    Tora, L.5    Gronemeyer, H.6    Chambon, P.7
  • 23
    • 0033731791 scopus 로고    scopus 로고
    • The classical progesterone receptor mediates Xenopus oocyte maturation through a nongenomic mechanism
    • Bayaa, M.; Booth, R. A.; Sheng, Y.; Liu, X. J. The classical progesterone receptor mediates Xenopus oocyte maturation through a nongenomic mechanism Proc. Natl. Acad. Sci. U. S. A. 2000, 97 (23) 12607-12612
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , Issue.23 , pp. 12607-12612
    • Bayaa, M.1    Booth, R.A.2    Sheng, Y.3    Liu, X.J.4
  • 24
    • 20444447713 scopus 로고    scopus 로고
    • Transcription-dependent and transcription-independent functions of the classical progesterone receptor in Xenopus ovaries
    • Liu, X. S.; Ma, C.; Hamam, A.-W.; Liu, X. J. Transcription-dependent and transcription-independent functions of the classical progesterone receptor in Xenopus ovaries Dev. Biol. 2005, 283 (1) 180-190
    • (2005) Dev. Biol. , vol.283 , Issue.1 , pp. 180-190
    • Liu, X.S.1    Ma, C.2    Hamam, A.-W.3    Liu, X.J.4
  • 25
    • 0034687770 scopus 로고    scopus 로고
    • Identification of XPR-1, a progesterone receptor required for Xenopus oocyte activation
    • Tian, J.; Kim, S.; Heilig, E.; Ruderman, J. V. Identification of XPR-1, a progesterone receptor required for Xenopus oocyte activation Proc. Natl. Acad. Sci. U. S. A. 2000, 97 (26) 14358-14363
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , Issue.26 , pp. 14358-14363
    • Tian, J.1    Kim, S.2    Heilig, E.3    Ruderman, J.V.4
  • 27
    • 79952823470 scopus 로고    scopus 로고
    • Cloning, pharmacological characterization, and expression analysis of Atlantic salmon (Salmo salar L.) nuclear progesterone receptor
    • Chen, S. X.; Bogerd, J.; Andersson, E.; Almeida, F. F. L.; Taranger, G. L.; Schulz, R. W. Cloning, pharmacological characterization, and expression analysis of Atlantic salmon (Salmo salar L.) nuclear progesterone receptor Reproduction 2011, 141 (4) 491-500
    • (2011) Reproduction , vol.141 , Issue.4 , pp. 491-500
    • Chen, S.X.1    Bogerd, J.2    Andersson, E.3    Almeida, F.F.L.4    Taranger, G.L.5    Schulz, R.W.6
  • 28
    • 84865288393 scopus 로고    scopus 로고
    • Cloning, pharmacological characterization and expression analysis of Atlantic cod (Gadus morhua, L.) nuclear progesterone receptor
    • Chen, S. X.; Almeida, F. F. L.; Andersson, E.; Taranger, G. L.; Schmidt, R.; Schulz, R. W.; Bogerd, J. Cloning, pharmacological characterization and expression analysis of Atlantic cod (Gadus morhua, L.) nuclear progesterone receptor Gen. Comp. Endocrinol. 2012, 179 (1) 71-77
    • (2012) Gen. Comp. Endocrinol. , vol.179 , Issue.1 , pp. 71-77
    • Chen, S.X.1    Almeida, F.F.L.2    Andersson, E.3    Taranger, G.L.4    Schmidt, R.5    Schulz, R.W.6    Bogerd, J.7
  • 29
    • 0037005983 scopus 로고    scopus 로고
    • A novel progestogen receptor subtype in the Japanese eel, Anguilla japonica
    • Ikeuchi, T.; Todo, T.; Kobayashi, T.; Nagahama, Y. A novel progestogen receptor subtype in the Japanese eel, Anguilla japonica FEBS Lett. 2002, 510 (1-2) 77-82
    • (2002) FEBS Lett. , vol.510 , Issue.12 , pp. 77-82
    • Ikeuchi, T.1    Todo, T.2    Kobayashi, T.3    Nagahama, Y.4
  • 30
    • 0033622318 scopus 로고    scopus 로고
    • Characterization of a testicular 17α,20β-dihydroxy-4-pregnen-3-one (a spermiation-inducing steroid in fish) receptor from a teleost, Japanese eel (Anguilla japonica)
    • Todo, T.; Ikeuchi, T.; Kobayashi, T.; Kajiura-Kobayashi, H.; Suzuki, K.; Yoshikuni, M.; Yamauchi, K.; Nagahama, Y. Characterization of a testicular 17α,20β-dihydroxy-4-pregnen-3-one (a spermiation-inducing steroid in fish) receptor from a teleost, Japanese eel (Anguilla japonica) FEBS Lett. 2000, 465 (1) 12-17
    • (2000) FEBS Lett. , vol.465 , Issue.1 , pp. 12-17
    • Todo, T.1    Ikeuchi, T.2    Kobayashi, T.3    Kajiura-Kobayashi, H.4    Suzuki, K.5    Yoshikuni, M.6    Yamauchi, K.7    Nagahama, Y.8
  • 31
    • 84871510472 scopus 로고    scopus 로고
    • Alternative splicing of the nuclear progestin receptor in a perciform teleost generates novel mechanisms of dominant-negative transcriptional regulation
    • Zapater, C.; Chauvigné, F.; Fernández-Gómez, B.; Finn, R. N.; Cerdà, J. Alternative splicing of the nuclear progestin receptor in a perciform teleost generates novel mechanisms of dominant-negative transcriptional regulation Gen. Comp. Endocrinol. 2013, 182, 24-40
    • (2013) Gen. Comp. Endocrinol. , vol.182 , pp. 24-40
    • Zapater, C.1    Chauvigné, F.2    Fernández-Gómez, B.3    Finn, R.N.4    Cerdà, J.5
  • 32
    • 77950365917 scopus 로고    scopus 로고
    • Characterization and expression of the nuclear progestin receptor in zebrafish gonads and brain
    • Hanna, R. N.; Daly, S. C. J.; Pang, Y.; Anglade, I.; Kah, O.; Thomas, P.; Zhu, Y. Characterization and expression of the nuclear progestin receptor in zebrafish gonads and brain Biol. Reprod. 2010, 82 (1) 112-122
    • (2010) Biol. Reprod. , vol.82 , Issue.1 , pp. 112-122
    • Hanna, R.N.1    Daly, S.C.J.2    Pang, Y.3    Anglade, I.4    Kah, O.5    Thomas, P.6    Zhu, Y.7
  • 33
    • 79956289710 scopus 로고    scopus 로고
    • Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception
    • Africander, D.; Verhoog, N.; Hapgood, J. P. Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception Steroids 2011, 76 (7) 636-652
    • (2011) Steroids , vol.76 , Issue.7 , pp. 636-652
    • Africander, D.1    Verhoog, N.2    Hapgood, J.P.3
  • 34
    • 1942439064 scopus 로고    scopus 로고
    • Pharmacological profile of progestins
    • Sitruk-Ware, R. Pharmacological profile of progestins Maturitas 2004, 47 (4) 277-283
    • (2004) Maturitas , vol.47 , Issue.4 , pp. 277-283
    • Sitruk-Ware, R.1
  • 35
    • 0032976891 scopus 로고    scopus 로고
    • Amphibians as a model to study endocrine disruptors: I. Environmental pollution and estrogen receptor binding
    • Lutz, I.; Kloas, W. Amphibians as a model to study endocrine disruptors: I. Environmental pollution and estrogen receptor binding Sci. Total Environ. 1999, 225 (1-2) 49-57
    • (1999) Sci. Total Environ. , vol.225 , Issue.12 , pp. 49-57
    • Lutz, I.1    Kloas, W.2
  • 38
    • 0033735999 scopus 로고    scopus 로고
    • Contraceptive progestins. Various 11-substituents combined with four 17-substituents: 17α-ethynyl, five- and six-membered spiromethylene ethers or six-membered spiromethylene lactones
    • Schoonen, W. G. E..; Deckers, G.; de Gooijer, M..; de Ries, R.; Mathijssen-Mommers, G.; Hamersma, H.; Kloosterboer, H.. Contraceptive progestins. Various 11-substituents combined with four 17-substituents: 17α-ethynyl, five- and six-membered spiromethylene ethers or six-membered spiromethylene lactones J. Steroid Biochem. Mol. Biol. 2000, 74 (3) 109-123
    • (2000) J. Steroid Biochem. Mol. Biol. , vol.74 , Issue.3 , pp. 109-123
    • Schoonen, W.G.E.1    Deckers, G.2    De Gooijer, M.3    De Ries, R.4    Mathijssen-Mommers, G.5    Hamersma, H.6    Kloosterboer, H.7
  • 39
    • 0028871092 scopus 로고
    • Characterization of a progestogen receptor in the ovary of the spotted seatrout, Cynoscion nebulosus
    • Pinter, J.; Thomas, P. Characterization of a progestogen receptor in the ovary of the spotted seatrout, Cynoscion nebulosus Biol. Reprod. 1995, 52 (3) 667-675
    • (1995) Biol. Reprod. , vol.52 , Issue.3 , pp. 667-675
    • Pinter, J.1    Thomas, P.2
  • 40
    • 0030914892 scopus 로고    scopus 로고
    • The ovarian progestogen receptor in the spotted seatrout, Cynoscion nebulosus, demonstrates steroid specificity different from progesterone receptors in other vertebrates
    • Pinter, J.; Thomas, P. The ovarian progestogen receptor in the spotted seatrout, Cynoscion nebulosus, demonstrates steroid specificity different from progesterone receptors in other vertebrates J. Steroid Biochem. Mol. Biol. 1997, 60 (1-2) 113-119
    • (1997) J. Steroid Biochem. Mol. Biol. , vol.60 , Issue.12 , pp. 113-119
    • Pinter, J.1    Thomas, P.2
  • 42
    • 84856116980 scopus 로고    scopus 로고
    • Rapid steroid hormone actions initiated at the cell surface and the receptors that mediate them with an emphasis on recent progress in fish models
    • Thomas, P. Rapid steroid hormone actions initiated at the cell surface and the receptors that mediate them with an emphasis on recent progress in fish models Gen. Comp. Endocrinol. 2012, 175 (3) 367-383
    • (2012) Gen. Comp. Endocrinol. , vol.175 , Issue.3 , pp. 367-383
    • Thomas, P.1
  • 43
    • 44249092617 scopus 로고    scopus 로고
    • Regulation of oocyte maturation in fish
    • S-1
    • Nagahama, Y.; Yamashita, M. Regulation of oocyte maturation in fish Dev., Growth Differ. 2008, 50 (S-1) 195-S219
    • (2008) Dev., Growth Differ. , vol.50 , pp. 195-S219
    • Nagahama, Y.1    Yamashita, M.2
  • 44
    • 0030731197 scopus 로고    scopus 로고
    • Correlation between binding affinities of C21 steroids for the maturation-inducing steroid membrane receptor in spotted seatrout ovaries and their agonist and antagonist activities in an oocyte maturation bioassay
    • Thomas, P.; Das, S. Correlation between binding affinities of C21 steroids for the maturation-inducing steroid membrane receptor in spotted seatrout ovaries and their agonist and antagonist activities in an oocyte maturation bioassay Biol. Reprod. 1997, 57 (5) 999-1007
    • (1997) Biol. Reprod. , vol.57 , Issue.5 , pp. 999-1007
    • Thomas, P.1    Das, S.2
  • 45
    • 33846418071 scopus 로고    scopus 로고
    • Steroid and G protein binding characteristics of the seatrout and human progestin membrane receptor α subtypes and their evolutionary origins
    • Thomas, P.; Pang, Y.; Dong, J.; Groenen, P.; Kelder, J.; de Vlieg, J.; Zhu, Y.; Tubbs, C. Steroid and G protein binding characteristics of the seatrout and human progestin membrane receptor α subtypes and their evolutionary origins Endocrinology 2007, 148 (2) 705-718
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 705-718
    • Thomas, P.1    Pang, Y.2    Dong, J.3    Groenen, P.4    Kelder, J.5    De Vlieg, J.6    Zhu, Y.7    Tubbs, C.8
  • 47
    • 50449103458 scopus 로고    scopus 로고
    • Sex hormone-binding globulin in fish gills is a portal for sex steroids breached by xenobiotics
    • Miguel-Queralt, S.; Hammond, G. L. Sex hormone-binding globulin in fish gills is a portal for sex steroids breached by xenobiotics Endocrinology 2008, 149 (9) 4269-4275
    • (2008) Endocrinology , vol.149 , Issue.9 , pp. 4269-4275
    • Miguel-Queralt, S.1    Hammond, G.L.2
  • 48
    • 0033833321 scopus 로고    scopus 로고
    • Drospirenone: Pharmacology and pharmacokinetics of a unique progestogen
    • Krattenmacher, R. Drospirenone: Pharmacology and pharmacokinetics of a unique progestogen Contraception 2000, 62 (1) 29-38
    • (2000) Contraception , vol.62 , Issue.1 , pp. 29-38
    • Krattenmacher, R.1
  • 50
    • 0027051398 scopus 로고
    • Dihydrospirorenone (ZK30595): A novel synthetic progestagen-characterization of binding to different receptor proteins
    • Pollow, K.; Juchem, M.; Elger, W.; Jacobi, N.; Hoffmann, G.; Möbus, V. Dihydrospirorenone (ZK30595): A novel synthetic progestagen-characterization of binding to different receptor proteins Contraception 1992, 46 (6) 561-574
    • (1992) Contraception , vol.46 , Issue.6 , pp. 561-574
    • Pollow, K.1    Juchem, M.2    Elger, W.3    Jacobi, N.4    Hoffmann, G.5    Möbus, V.6
  • 51
    • 0022474605 scopus 로고
    • Inhibition of androgen receptor binding by natural and synthetic steroids in cultured human genital skin fibroblasts
    • Breiner, M.; Romalo, G.; Schweikert, H.-U. Inhibition of androgen receptor binding by natural and synthetic steroids in cultured human genital skin fibroblasts Klin. Wochenschr. 1986, 64 (16) 732-737
    • (1986) Klin. Wochenschr. , vol.64 , Issue.16 , pp. 732-737
    • Breiner, M.1    Romalo, G.2    Schweikert, H.-U.3
  • 52
    • 25844505069 scopus 로고    scopus 로고
    • Synthetic progestins used in HRT have different glucocorticoid agonist properties
    • Koubovec, D.; Ronacher, K.; Stubsrud, E.; Louw, A.; Hapgood, J. P. Synthetic progestins used in HRT have different glucocorticoid agonist properties Mol. Cell. Endocrinol. 2005, 242 (1-2) 23-32
    • (2005) Mol. Cell. Endocrinol. , vol.242 , Issue.12 , pp. 23-32
    • Koubovec, D.1    Ronacher, K.2    Stubsrud, E.3    Louw, A.4    Hapgood, J.P.5
  • 53
    • 0020539207 scopus 로고
    • Binding of progestins to the glucocorticoid receptor: Correlation to their glucocorticoid-like effects on in vitro functions of human mononuclear leukocytes
    • Kontula, K.; Paavonen, T.; Luukkainen, T.; Andersson, L. C. Binding of progestins to the glucocorticoid receptor: Correlation to their glucocorticoid-like effects on in vitro functions of human mononuclear leukocytes Biochem. Pharmacol. 1983, 32 (9) 1511-1518
    • (1983) Biochem. Pharmacol. , vol.32 , Issue.9 , pp. 1511-1518
    • Kontula, K.1    Paavonen, T.2    Luukkainen, T.3    Andersson, L.C.4
  • 54
    • 0028876786 scopus 로고
    • Characterization of the novel progestin gestodene by receptor binding studies and transactivation assays
    • Fuhrmann, U.; Slater, E. P.; Fritzemeier, K.-H. Characterization of the novel progestin gestodene by receptor binding studies and transactivation assays Contraception 1995, 51 (1) 45-52
    • (1995) Contraception , vol.51 , Issue.1 , pp. 45-52
    • Fuhrmann, U.1    Slater, E.P.2    Fritzemeier, K.-H.3
  • 55
    • 0025040579 scopus 로고
    • Relative binding affinity of norgestimate and other progestins for human sex hormone-binding globulin
    • Phillips, A.; Hahn, D. W.; McGuire, J. L. Relative binding affinity of norgestimate and other progestins for human sex hormone-binding globulin Steroids 1990, 55 (8) 373-375
    • (1990) Steroids , vol.55 , Issue.8 , pp. 373-375
    • Phillips, A.1    Hahn, D.W.2    McGuire, J.L.3
  • 57
    • 37649011457 scopus 로고    scopus 로고
    • Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile
    • Sasagawa, S.; Shimizu, Y.; Kami, H.; Takeuchi, T.; Mita, S.; Imada, K.; Kato, S.; Mizuguchi, K. Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile Steroids 2008, 73 (2) 222-231
    • (2008) Steroids , vol.73 , Issue.2 , pp. 222-231
    • Sasagawa, S.1    Shimizu, Y.2    Kami, H.3    Takeuchi, T.4    Mita, S.5    Imada, K.6    Kato, S.7    Mizuguchi, K.8
  • 58
    • 24144485432 scopus 로고    scopus 로고
    • Pharmacology of estrogens and progestogens: Influence of different routes of administration
    • S-1
    • Kuhl, H. Pharmacology of estrogens and progestogens: Influence of different routes of administration Climacteric 2005, 8 (S-1) 3-63
    • (2005) Climacteric , vol.8 , pp. 3-63
    • Kuhl, H.1
  • 59
    • 0033623603 scopus 로고    scopus 로고
    • Nestorone: A progestin with a unique pharmacological profile
    • Kumar, N.; Koide, S. S.; Tsong, Y.-Y.; Sundaram, K. Nestorone: A progestin with a unique pharmacological profile Steroids 2000, 65 (10-11) 629-636
    • (2000) Steroids , vol.65 , Issue.1011 , pp. 629-636
    • Kumar, N.1    Koide, S.S.2    Tsong, Y.-Y.3    Sundaram, K.4
  • 60
    • 0024993114 scopus 로고
    • Pharmacokinetics of oestrogens and progestogens
    • Kuhl, H. Pharmacokinetics of oestrogens and progestogens Maturitas 1990, 12 (3) 171-197
    • (1990) Maturitas , vol.12 , Issue.3 , pp. 171-197
    • Kuhl, H.1
  • 61
    • 0028962222 scopus 로고
    • Comparative progestational activity of norgestimate, levonorgestrel-oxime and levonorgestrel in the rat and binding of these compounds to the progesterone receptor
    • Kuhnz, W.; Fritzemeier, K. H.; Hegele-Hartung, C.; Krattenmacher, R. Comparative progestational activity of norgestimate, levonorgestrel-oxime and levonorgestrel in the rat and binding of these compounds to the progesterone receptor Contraception 1995, 51 (2) 131-139
    • (1995) Contraception , vol.51 , Issue.2 , pp. 131-139
    • Kuhnz, W.1    Fritzemeier, K.H.2    Hegele-Hartung, C.3    Krattenmacher, R.4
  • 62
    • 0030050821 scopus 로고    scopus 로고
    • Comparative Pharmacology of Newer Progestogens
    • Kuhl, H. Comparative Pharmacology of Newer Progestogens Drugs 1996, 51 (2) 188-215
    • (1996) Drugs , vol.51 , Issue.2 , pp. 188-215
    • Kuhl, H.1
  • 63
    • 4444339957 scopus 로고    scopus 로고
    • Induction of androgen receptor activity by norgestimate and norelgestromin in MDA-MB 231 breast cancer cells
    • Prifti, S.; Lelle, I.; Strowitzki, T.; Rabe, T. Induction of androgen receptor activity by norgestimate and norelgestromin in MDA-MB 231 breast cancer cells Gynecol. Endocrinol. 2004, 19 (1) 18-21
    • (2004) Gynecol. Endocrinol. , vol.19 , Issue.1 , pp. 18-21
    • Prifti, S.1    Lelle, I.2    Strowitzki, T.3    Rabe, T.4
  • 64
    • 1642430672 scopus 로고
    • "classical" and "non-classical" reproductive steroids in fish
    • Kime, D. "Classical" and "non-classical" reproductive steroids in fish Rev. Fish Biol. Fish 1993, 3 (2) 160-180
    • (1993) Rev. Fish Biol. Fish , vol.3 , Issue.2 , pp. 160-180
    • Kime, D.1
  • 65
    • 76449085306 scopus 로고    scopus 로고
    • The role of the maturation-inducing steroid, 17,20β-dihydroxypregn-4-en-3-one, in male fishes: A review
    • Scott, A. P.; Sumpter, J. P.; Stacey, N. The role of the maturation-inducing steroid, 17,20β-dihydroxypregn-4-en-3-one, in male fishes: A review J. Fish Biol. 2010, 76 (1) 183-224
    • (2010) J. Fish Biol. , vol.76 , Issue.1 , pp. 183-224
    • Scott, A.P.1    Sumpter, J.P.2    Stacey, N.3
  • 66
    • 8544252436 scopus 로고    scopus 로고
    • Physiological action of progesterone in target tissues
    • Graham, J. D.; Clarke, C. L. Physiological action of progesterone in target tissues Endocr. Rev. 1997, 18 (4) 502-519
    • (1997) Endocr. Rev. , vol.18 , Issue.4 , pp. 502-519
    • Graham, J.D.1    Clarke, C.L.2
  • 68
    • 44249088793 scopus 로고    scopus 로고
    • Synthesis and Function of Hypothalamic Neuroprogesterone in Reproduction
    • Micevych, P.; Sinchak, K. Synthesis and Function of Hypothalamic Neuroprogesterone in Reproduction Endocrinology 2008, 149 (6) 2739-2742
    • (2008) Endocrinology , vol.149 , Issue.6 , pp. 2739-2742
    • Micevych, P.1    Sinchak, K.2
  • 69
    • 63649156363 scopus 로고    scopus 로고
    • Progestin functions in vertebrate gametes mediated by membrane progestin receptors (mPRs): Identification of mPRα on human sperm and its association with sperm motility
    • Thomas, P.; Tubbs, C.; Garry, V. F. Progestin functions in vertebrate gametes mediated by membrane progestin receptors (mPRs): Identification of mPRα on human sperm and its association with sperm motility Steroids 2009, 74 (7) 614-621
    • (2009) Steroids , vol.74 , Issue.7 , pp. 614-621
    • Thomas, P.1    Tubbs, C.2    Garry, V.F.3
  • 70
    • 0029049431 scopus 로고
    • Sulfated 17,20β-Dihydroxy-4-pregnen-3-one Functions as a Potent and Specific Olfactory Stimulant with Pheromonal Actions in the Goldfish
    • Sorensen, P. W.; Scott, A. P.; Stacey, N. E.; Bowdin, L. Sulfated 17,20β-Dihydroxy-4-pregnen-3-one Functions as a Potent and Specific Olfactory Stimulant with Pheromonal Actions in the Goldfish Gen. Comp. Endocrinol. 1995, 100 (1) 128-142
    • (1995) Gen. Comp. Endocrinol. , vol.100 , Issue.1 , pp. 128-142
    • Sorensen, P.W.1    Scott, A.P.2    Stacey, N.E.3    Bowdin, L.4
  • 71
    • 33646598033 scopus 로고    scopus 로고
    • Progestin is an essential factor for the initiation of the meiosis in spermatogenetic cells of the eel
    • Miura, T.; Higuchi, M.; Ozaki, Y.; Ohta, T.; Miura, C. Progestin is an essential factor for the initiation of the meiosis in spermatogenetic cells of the eel Proc. Natl. Acad. Sci. U. S. A. 2006, 103 (19) 7333-7338
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , Issue.19 , pp. 7333-7338
    • Miura, T.1    Higuchi, M.2    Ozaki, Y.3    Ohta, T.4    Miura, C.5
  • 72
    • 35548942155 scopus 로고    scopus 로고
    • A Progestin and an Estrogen Regulate Early Stages of Oogenesis in Fish
    • Miura, C.; Higashino, T.; Miura, T. A Progestin and an Estrogen Regulate Early Stages of Oogenesis in Fish Biol. Reprod. 2007, 77 (5) 822-828
    • (2007) Biol. Reprod. , vol.77 , Issue.5 , pp. 822-828
    • Miura, C.1    Higashino, T.2    Miura, T.3
  • 73
    • 84874418404 scopus 로고    scopus 로고
    • A progestin (17α,20β-dihydroxy-4-pregnen-3-one) stimulates early stages of spermatogenesis in zebrafish
    • Chen, S. X.; Bogerd, J.; Schoonen, N. E.; Martijn, J.; de Waal, P. P.; Schulz, R. W. A progestin (17α,20β-dihydroxy-4-pregnen-3-one) stimulates early stages of spermatogenesis in zebrafish Gen. Comp. Endocrinol. 2013, 185, 1-9
    • (2013) Gen. Comp. Endocrinol. , vol.185 , pp. 1-9
    • Chen, S.X.1    Bogerd, J.2    Schoonen, N.E.3    Martijn, J.4    De Waal, P.P.5    Schulz, R.W.6
  • 74
    • 84901011405 scopus 로고    scopus 로고
    • The role of pregnancy-associated hormones in the development and function of regulatory B cells
    • Muzzio, D.; Zygmunt, M.; Jensen, F. The role of pregnancy-associated hormones in the development and function of regulatory B cells Front. Endocrinol. 2014, 5 39
    • (2014) Front. Endocrinol. , vol.5 , pp. 39
    • Muzzio, D.1    Zygmunt, M.2    Jensen, F.3
  • 75
    • 84876687912 scopus 로고    scopus 로고
    • Protective actions of progesterone in the cardiovascular system: Potential role of membrane progesterone receptors (mPRs) in mediating rapid effects
    • Thomas, P.; Pang, Y. Protective actions of progesterone in the cardiovascular system: Potential role of membrane progesterone receptors (mPRs) in mediating rapid effects Steroids 2013, 78 (6) 583-588
    • (2013) Steroids , vol.78 , Issue.6 , pp. 583-588
    • Thomas, P.1    Pang, Y.2
  • 77
    • 77955556274 scopus 로고    scopus 로고
    • Reproductive responses in fathead minnow and Japanese medaka following exposure to a synthetic progestin, Norethindrone
    • Paulos, P.; Runnalls, T. J.; Nallani, G.; La Point, T.; Scott, A. P.; Sumpter, J. P.; Huggett, D. B. Reproductive responses in fathead minnow and Japanese medaka following exposure to a synthetic progestin, Norethindrone Aquat. Toxicol. 2010, 99 (2) 256-262
    • (2010) Aquat. Toxicol. , vol.99 , Issue.2 , pp. 256-262
    • Paulos, P.1    Runnalls, T.J.2    Nallani, G.3    La Point, T.4    Scott, A.P.5    Sumpter, J.P.6    Huggett, D.B.7
  • 78
    • 84875079683 scopus 로고    scopus 로고
    • Disrupted oogenesis in the frog Xenopus tropicalis after exposure to environmental progestin concentrations
    • Säfholm, M.; Norder, A.; Fick, J.; Berg, C. Disrupted oogenesis in the frog Xenopus tropicalis after exposure to environmental progestin concentrations Biol. Reprod. 2012, 86 (4) 126
    • (2012) Biol. Reprod. , vol.86 , Issue.4 , pp. 126
    • Säfholm, M.1    Norder, A.2    Fick, J.3    Berg, C.4
  • 79
    • 84886263441 scopus 로고    scopus 로고
    • Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 1. Reproductive and early developmental effects
    • Blüthgen, N.; Castiglioni, S.; Sumpter, J. P.; Fent, K. Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 1. Reproductive and early developmental effects Aquat. Toxicol. 2013, 144-145, 83-95
    • (2013) Aquat. Toxicol. , vol.144-145 , pp. 83-95
    • Blüthgen, N.1    Castiglioni, S.2    Sumpter, J.P.3    Fent, K.4
  • 80
    • 84874081567 scopus 로고    scopus 로고
    • The synthetic progestin levonorgestrel is a potent androgen in the three-spined stickleback (Gasterosteus aculeatus)
    • Svensson, J.; Fick, J.; Brandt, I.; Brunström, B. The synthetic progestin levonorgestrel is a potent androgen in the three-spined stickleback (Gasterosteus aculeatus) Environ. Sci. Technol. 2013, 47 (4) 2043-2051
    • (2013) Environ. Sci. Technol. , vol.47 , Issue.4 , pp. 2043-2051
    • Svensson, J.1    Fick, J.2    Brandt, I.3    Brunström, B.4
  • 81
    • 84859881520 scopus 로고    scopus 로고
    • The synthetic progestogen, levonorgestrel, but not natural progesterone, affects male mate calling behavior of Xenopus laevis
    • Hoffmann, F.; Kloas, W. The synthetic progestogen, levonorgestrel, but not natural progesterone, affects male mate calling behavior of Xenopus laevis Gen. Comp. Endocrinol. 2012, 176 (3) 385-390
    • (2012) Gen. Comp. Endocrinol. , vol.176 , Issue.3 , pp. 385-390
    • Hoffmann, F.1    Kloas, W.2
  • 82
    • 84924085168 scopus 로고    scopus 로고
    • Female specific reproductive toxicity of environmental progestin in amphibians
    • Safholm, M.; Fick, J.; Berg, C. Female specific reproductive toxicity of environmental progestin in amphibians Comp. Biochem. Physiol. A 2012, 163 (1 S56
    • (2012) Comp. Biochem. Physiol. A , vol.163 , Issue.1 , pp. 56
    • Safholm, M.1    Fick, J.2    Berg, C.3
  • 83
    • 84901631826 scopus 로고    scopus 로고
    • The progestin levonorgestrel disrupts gonadotropin expression and sex steroid levels in pubertal roach (Rutilus rutilus)
    • Kroupova, H. K.; Trubiroha, A.; Lorenz, C.; Contardo-Jara, V.; Lutz, I.; Grabic, R.; Kocour, M.; Kloas, W. The progestin levonorgestrel disrupts gonadotropin expression and sex steroid levels in pubertal roach (Rutilus rutilus) Aquat. Toxicol. 2014, 154, 154-162
    • (2014) Aquat. Toxicol. , vol.154 , pp. 154-162
    • Kroupova, H.K.1    Trubiroha, A.2    Lorenz, C.3    Contardo-Jara, V.4    Lutz, I.5    Grabic, R.6    Kocour, M.7    Kloas, W.8
  • 84
    • 81855199721 scopus 로고    scopus 로고
    • The synthetic gestagen levonorgestrel disrupts sexual development in Xenopus laevis by affecting gene expression of pituitary gonadotropins and gonadal steroidogenic enzymes
    • Lorenz, C.; Contardo-Jara, V.; Trubiroha, A.; Krueger, A.; Viehmann, V.; Wiegand, C.; Pflugmacher, S.; Nuetzmann, G.; Lutz, I.; Kloas, W. The synthetic gestagen levonorgestrel disrupts sexual development in Xenopus laevis by affecting gene expression of pituitary gonadotropins and gonadal steroidogenic enzymes Toxicol. Sci. 2011, 124 (2) 311-319
    • (2011) Toxicol. Sci. , vol.124 , Issue.2 , pp. 311-319
    • Lorenz, C.1    Contardo-Jara, V.2    Trubiroha, A.3    Krueger, A.4    Viehmann, V.5    Wiegand, C.6    Pflugmacher, S.7    Nuetzmann, G.8    Lutz, I.9    Kloas, W.10
  • 85
    • 84891109771 scopus 로고    scopus 로고
    • Environmental concentrations of an androgenic progestin disrupts the seasonal breeding cycle in male three-spined stickleback (Gasterosteus aculeatus)
    • Svensson, J.; Fick, J.; Brandt, I.; Brunström, B. Environmental concentrations of an androgenic progestin disrupts the seasonal breeding cycle in male three-spined stickleback (Gasterosteus aculeatus) Aquat. Toxicol. 2014, 147 (0) 84-91
    • (2014) Aquat. Toxicol. , vol.147 , Issue.0 , pp. 84-91
    • Svensson, J.1    Fick, J.2    Brandt, I.3    Brunström, B.4
  • 86
    • 79955770646 scopus 로고    scopus 로고
    • Effects of progesterone on sperm motility in fathead minnow (Pimephales promelas)
    • Murack, P. J.; Parrish, J.; Barry, T. P. Effects of progesterone on sperm motility in fathead minnow (Pimephales promelas) Aquat. Toxicol. 2011, 104 (1-2) 121-125
    • (2011) Aquat. Toxicol. , vol.104 , Issue.12 , pp. 121-125
    • Murack, P.J.1    Parrish, J.2    Barry, T.P.3
  • 87
    • 84896109883 scopus 로고    scopus 로고
    • The synthetic progestin megestrol acetate adversely affects zebrafish reproduction
    • Han, J.; Wang, Q.; Wang, X.; Li, Y.; Wen, S.; Liu, S.; Ying, G.; Guo, Y.; Zhou, B. The synthetic progestin megestrol acetate adversely affects zebrafish reproduction Aquat. Toxicol. 2014, 150, 66-72
    • (2014) Aquat. Toxicol. , vol.150 , pp. 66-72
    • Han, J.1    Wang, Q.2    Wang, X.3    Li, Y.4    Wen, S.5    Liu, S.6    Ying, G.7    Guo, Y.8    Zhou, B.9
  • 88
    • 84893509530 scopus 로고    scopus 로고
    • Levonorgestrel exposure to fathead minnows (Pimephales promelas) alters survival, growth, steroidogenic gene expression and hormone production
    • Overturf, M. D.; Overturf, C. L.; Carty, D. R.; Hala, D.; Huggett, D. B. Levonorgestrel exposure to fathead minnows (Pimephales promelas) alters survival, growth, steroidogenic gene expression and hormone production Aquat. Toxicol. 2014, 148, 152-161
    • (2014) Aquat. Toxicol. , vol.148 , pp. 152-161
    • Overturf, M.D.1    Overturf, C.L.2    Carty, D.R.3    Hala, D.4    Huggett, D.B.5
  • 89
    • 84886235847 scopus 로고    scopus 로고
    • Progesterone alters global transcription profiles at environmental concentrations in brain and ovary of female zebrafish (Danio rerio)
    • Zucchi, S.; Castiglioni, S.; Fent, K. Progesterone alters global transcription profiles at environmental concentrations in brain and ovary of female zebrafish (Danio rerio) Environ. Sci. Technol. 2013, 47 (21) 12548-12556
    • (2013) Environ. Sci. Technol. , vol.47 , Issue.21 , pp. 12548-12556
    • Zucchi, S.1    Castiglioni, S.2    Fent, K.3
  • 90
    • 84898998276 scopus 로고    scopus 로고
    • Transcriptional and physiological responses induced by binary mixtures of drospirenone and progesterone in zebrafish (Danio rerio)
    • Zucchi, S.; Mirbahai, L.; Castiglioni, S.; Fent, K. Transcriptional and physiological responses induced by binary mixtures of drospirenone and progesterone in zebrafish (Danio rerio) Environ. Sci. Technol. 2014, 48 (6) 3523-3531
    • (2014) Environ. Sci. Technol. , vol.48 , Issue.6 , pp. 3523-3531
    • Zucchi, S.1    Mirbahai, L.2    Castiglioni, S.3    Fent, K.4
  • 91
    • 11444251221 scopus 로고    scopus 로고
    • Sexually mature male goldfish release large quantities of androstenedione into the water where it functions as a pheromone
    • Sorensen, P. W.; Pinillos, M.; Scott, A. P. Sexually mature male goldfish release large quantities of androstenedione into the water where it functions as a pheromone Gen. Comp. Endocrinol. 2005, 140 (3) 164-175
    • (2005) Gen. Comp. Endocrinol. , vol.140 , Issue.3 , pp. 164-175
    • Sorensen, P.W.1    Pinillos, M.2    Scott, A.P.3
  • 93
    • 79959915587 scopus 로고    scopus 로고
    • In vivo treatment with progestogens causes immunosuppression of carp Cyprinus carpio leucocytes by affecting nitric oxide production and arginase activity
    • Pietsch, C.; Neumann, N.; Preuer, T.; Kloas, W. In vivo treatment with progestogens causes immunosuppression of carp Cyprinus carpio leucocytes by affecting nitric oxide production and arginase activity J. Fish Biol. 2011, 79 (1) 53-69
    • (2011) J. Fish Biol. , vol.79 , Issue.1 , pp. 53-69
    • Pietsch, C.1    Neumann, N.2    Preuer, T.3    Kloas, W.4
  • 94
    • 0036669063 scopus 로고    scopus 로고
    • Suppression in function of phagocytic cells in common carp Cyprinus carpio L. Injected with estradiol, progesterone or 11-ketotestosterone
    • Watanuki, H.; Yamaguchi, T.; Sakai, M. Suppression in function of phagocytic cells in common carp Cyprinus carpio L. injected with estradiol, progesterone or 11-ketotestosterone Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol. 2002, 132 (4) 407-413
    • (2002) Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol. , vol.132 , Issue.4 , pp. 407-413
    • Watanuki, H.1    Yamaguchi, T.2    Sakai, M.3
  • 95
    • 0035026322 scopus 로고    scopus 로고
    • Effects of estradiol, progesterone and testosterone on the function of carp, Cyprinus carpio, phagocytes in vitro
    • Yamaguchi, T.; Watanuki, H.; Sakai, M. Effects of estradiol, progesterone and testosterone on the function of carp, Cyprinus carpio, phagocytes in vitro Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol. 2001, 129 (1) 49-55
    • (2001) Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol. , vol.129 , Issue.1 , pp. 49-55
    • Yamaguchi, T.1    Watanuki, H.2    Sakai, M.3
  • 96
    • 80052462254 scopus 로고    scopus 로고
    • The synthetic gestagen levonorgestrel impairs metamorphosis in Xenopus laevis by disruption of the thyroid system
    • Lorenz, C.; Contardo-Jara, V.; Pflugmacher, S.; Wiegand, C.; Nuetzmann, G.; Lutz, I.; Kloas, W. The synthetic gestagen levonorgestrel impairs metamorphosis in Xenopus laevis by disruption of the thyroid system Toxicol. Sci. 2011, 123 (1) 94-102
    • (2011) Toxicol. Sci. , vol.123 , Issue.1 , pp. 94-102
    • Lorenz, C.1    Contardo-Jara, V.2    Pflugmacher, S.3    Wiegand, C.4    Nuetzmann, G.5    Lutz, I.6    Kloas, W.7
  • 97
    • 1942485419 scopus 로고    scopus 로고
    • Effects of a model androgen (methyl testosterone) and a model anti-androgen (cyproterone acetate) on reproductive endocrine endpoints in a short-term adult mummichog (Fundulus heteroclitus) bioassay
    • Sharpe, R. L.; MacLatchy, D. L.; Courtenay, S. C.; Van Der Kraak, G. J. Effects of a model androgen (methyl testosterone) and a model anti-androgen (cyproterone acetate) on reproductive endocrine endpoints in a short-term adult mummichog (Fundulus heteroclitus) bioassay Aquat. Toxicol. 2004, 67 (3) 203-215
    • (2004) Aquat. Toxicol. , vol.67 , Issue.3 , pp. 203-215
    • Sharpe, R.L.1    Maclatchy, D.L.2    Courtenay, S.C.3    Van Der Kraak, G.J.4
  • 99
    • 84886233028 scopus 로고    scopus 로고
    • Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 2. Gene expression analysis and in vitro activity
    • Blüthgen, N.; Sumpter, J. P.; Odermatt, A.; Fent, K. Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 2. Gene expression analysis and in vitro activity Aquat. Toxicol. 2013, 144-145, 96-104
    • (2013) Aquat. Toxicol. , vol.144-145 , pp. 96-104
    • Blüthgen, N.1    Sumpter, J.P.2    Odermatt, A.3    Fent, K.4
  • 102
    • 84878365454 scopus 로고    scopus 로고
    • Effects of steroid hormones on reproduction- and detoxification-related gene expression in adult male mosquitofish, Gambusia affinis
    • Huang, G.-Y.; Ying, G.-G.; Liang, Y.-Q.; Liu, Y.-S.; Liu, S.-S. Effects of steroid hormones on reproduction- and detoxification-related gene expression in adult male mosquitofish, Gambusia affinis Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol. 2013, 158 (1) 36-43
    • (2013) Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol. , vol.158 , Issue.1 , pp. 36-43
    • Huang, G.-Y.1    Ying, G.-G.2    Liang, Y.-Q.3    Liu, Y.-S.4    Liu, S.-S.5
  • 103
    • 0038060708 scopus 로고    scopus 로고
    • Effects of the antiandrogens, vinclozolin and cyproterone acetate on gonadal development in the Japanese medaka (Oryzias latipes)
    • Kiparissis, Y.; Metcalfe, T. L.; Balch, G. C.; Metcalfe, C. D. Effects of the antiandrogens, vinclozolin and cyproterone acetate on gonadal development in the Japanese medaka (Oryzias latipes) Aquat. Toxicol. 2003, 63 (4) 391-403
    • (2003) Aquat. Toxicol. , vol.63 , Issue.4 , pp. 391-403
    • Kiparissis, Y.1    Metcalfe, T.L.2    Balch, G.C.3    Metcalfe, C.D.4
  • 104
    • 79952350029 scopus 로고    scopus 로고
    • Early life progestin exposure causes arrested oocyte development, oviductal agenesis and sterility in adult Xenopus tropicalis frogs
    • Kvarnryd, M.; Grabic, R.; Brandt, I.; Berg, C. Early life progestin exposure causes arrested oocyte development, oviductal agenesis and sterility in adult Xenopus tropicalis frogs Aquat. Toxicol. 2011, 103 (1-2) 18-24
    • (2011) Aquat. Toxicol. , vol.103 , Issue.12 , pp. 18-24
    • Kvarnryd, M.1    Grabic, R.2    Brandt, I.3    Berg, C.4
  • 105
    • 77957683227 scopus 로고    scopus 로고
    • Multi-residue analytical method for human pharmaceuticals and synthetic hormones in river water and sewage effluents by solid-phase extraction and liquid chromatography-tandem mass spectrometry
    • Al-Odaini, N. A.; Zakaria, M. P.; Yaziz, M. I.; Surif, S. Multi-residue analytical method for human pharmaceuticals and synthetic hormones in river water and sewage effluents by solid-phase extraction and liquid chromatography-tandem mass spectrometry J. Chromatogr. A 2010, 1217 (44) 6791-6806
    • (2010) J. Chromatogr. A , vol.1217 , Issue.44 , pp. 6791-6806
    • Al-Odaini, N.A.1    Zakaria, M.P.2    Yaziz, M.I.3    Surif, S.4
  • 106
    • 44649117929 scopus 로고    scopus 로고
    • Trace analysis of androgens and progestogens in environmental waters by ultra-performance liquid chromatography-electrospray tandem mass spectrometry
    • Chang, H.; Wu, S.; Hu, J.; Asami, M.; Kunikane, S. Trace analysis of androgens and progestogens in environmental waters by ultra-performance liquid chromatography-electrospray tandem mass spectrometry J. Chromatogr. A 2008, 1195 (1-2) 44-51
    • (2008) J. Chromatogr. A , vol.1195 , Issue.12 , pp. 44-51
    • Chang, H.1    Wu, S.2    Hu, J.3    Asami, M.4    Kunikane, S.5
  • 107
    • 50149109377 scopus 로고    scopus 로고
    • Analysis of natural and synthetic estrogenic endocrine disruptors in environmental waters using online preconcentration coupled with LC-APPI-MS/MS
    • Viglino, L.; Aboulfadl, K.; Prevost, M.; Sauve, S. Analysis of natural and synthetic estrogenic endocrine disruptors in environmental waters using online preconcentration coupled with LC-APPI-MS/MS Talanta 2008, 76 (5) 1088-1096
    • (2008) Talanta , vol.76 , Issue.5 , pp. 1088-1096
    • Viglino, L.1    Aboulfadl, K.2    Prevost, M.3    Sauve, S.4
  • 108
    • 84879103356 scopus 로고    scopus 로고
    • On-line solid-phase extraction coupled to liquid chromatography tandem mass spectrometry optimized for the analysis of steroid hormones in urban wastewaters
    • Fayad, P. B.; Prévost, M.; Sauvé, S. On-line solid-phase extraction coupled to liquid chromatography tandem mass spectrometry optimized for the analysis of steroid hormones in urban wastewaters Talanta 2013, 115 (0) 349-360
    • (2013) Talanta , vol.115 , Issue.0 , pp. 349-360
    • Fayad, P.B.1    Prévost, M.2    Sauvé, S.3
  • 109
    • 80054712999 scopus 로고    scopus 로고
    • The role of the acquisition methods in the analysis of natural and synthetic steroids and cholic acids by gas chromatography-mass spectrometry
    • Andrasi, N.; Helenkar, A.; Vasanits-Zsigrai, A.; Zaray, G.; Molnar-Perl, I. The role of the acquisition methods in the analysis of natural and synthetic steroids and cholic acids by gas chromatography-mass spectrometry J. Chromatogr. A 2011, 1218 (45) 8264-8272
    • (2011) J. Chromatogr. A , vol.1218 , Issue.45 , pp. 8264-8272
    • Andrasi, N.1    Helenkar, A.2    Vasanits-Zsigrai, A.3    Zaray, G.4    Molnar-Perl, I.5
  • 110
    • 84897503095 scopus 로고    scopus 로고
    • Identification of synthetic steroids in river water downstream from pharmaceutical manufacture discharges based on a bioanalytical approach and passive sampling
    • Creusot, N.; Aït-Aïssa, S.; Tapie, N.; Pardon, P.; Brion, F.; Sanchez, W.; Thybaud, E.; Porcher, J.-M.; Budzinski, H. Identification of synthetic steroids in river water downstream from pharmaceutical manufacture discharges based on a bioanalytical approach and passive sampling Environ. Sci. Technol. 2014, 48 (7) 3649-3657
    • (2014) Environ. Sci. Technol. , vol.48 , Issue.7 , pp. 3649-3657
    • Creusot, N.1    Aït-Aïssa, S.2    Tapie, N.3    Pardon, P.4    Brion, F.5    Sanchez, W.6    Thybaud, E.7    Porcher, J.-M.8    Budzinski, H.9
  • 111
    • 79951513972 scopus 로고    scopus 로고
    • Trace analysis of 28 steroids in surface water, wastewater and sludge samples by rapid resolution liquid chromatography-electrospray ionization tandem mass spectrometry
    • Liu, S.; Ying, G.-G.; Zhao, J.-L.; Chen, F.; Yang, B.; Zhou, L.-J.; Lai, H. Trace analysis of 28 steroids in surface water, wastewater and sludge samples by rapid resolution liquid chromatography-electrospray ionization tandem mass spectrometry J. Chromatogr. A 2011, 1218 (10) 1367-1378
    • (2011) J. Chromatogr. A , vol.1218 , Issue.10 , pp. 1367-1378
    • Liu, S.1    Ying, G.-G.2    Zhao, J.-L.3    Chen, F.4    Yang, B.5    Zhou, L.-J.6    Lai, H.7
  • 112
    • 0037085574 scopus 로고    scopus 로고
    • Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. Streams, 1999-2000: A national reconnaissance
    • Kolpin, D. W.; Furlong, E. T.; Meyer, M. T.; Thurman, E. M.; Zaugg, S. D.; Barber, L. B.; Buxton, H. T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: A national reconnaissance Environ. Sci. Technol. 2002, 36 (6) 1202-1211
    • (2002) Environ. Sci. Technol. , vol.36 , Issue.6 , pp. 1202-1211
    • Kolpin, D.W.1    Furlong, E.T.2    Meyer, M.T.3    Thurman, E.M.4    Zaugg, S.D.5    Barber, L.B.6    Buxton, H.T.7
  • 113
    • 47949133326 scopus 로고    scopus 로고
    • Analysis and occurrence of pharmaceuticals, estrogens, progestogens and polar pesticides in sewage treatment plant effluents, river water and drinking water in the Llobregat river basin (Barcelona, Spain)
    • Kuster, M.; López de Alda, M. J.; Hernando, M. D.; Petrovic, M.; Martín-Alonso, J.; Barceló, D. Analysis and occurrence of pharmaceuticals, estrogens, progestogens and polar pesticides in sewage treatment plant effluents, river water and drinking water in the Llobregat river basin (Barcelona, Spain) J. Hydrol. 2008, 358 (1-2) 112-123
    • (2008) J. Hydrol. , vol.358 , Issue.12 , pp. 112-123
    • Kuster, M.1    López De Alda, M.J.2    Hernando, M.D.3    Petrovic, M.4    Martín-Alonso, J.5    Barceló, D.6
  • 115
    • 34250843909 scopus 로고    scopus 로고
    • Rangeland grazing as a source of steroid hormones to surface waters
    • Kolodziej, E. P.; Sedlak, D. L. Rangeland grazing as a source of steroid hormones to surface waters Environ. Sci. Technol. 2007, 41 (10) 3514-3520
    • (2007) Environ. Sci. Technol. , vol.41 , Issue.10 , pp. 3514-3520
    • Kolodziej, E.P.1    Sedlak, D.L.2
  • 116
    • 67650578154 scopus 로고    scopus 로고
    • Presence of steroid hormones and antibiotics in surface water of agricultural, suburban and mixed-use areas
    • Velicu, M.; Suri, R. Presence of steroid hormones and antibiotics in surface water of agricultural, suburban and mixed-use areas Environ. Monit. Assess. 2009, 154 (1-4) 349-359
    • (2009) Environ. Monit. Assess. , vol.154 , Issue.14 , pp. 349-359
    • Velicu, M.1    Suri, R.2
  • 117
    • 78650417547 scopus 로고    scopus 로고
    • Occurrence of androgens and progestogens in wastewater treatment plants and receiving river waters: Comparison to estrogens
    • Chang, H.; Wan, Y.; Wu, S.; Fan, Z.; Hu, J. Occurrence of androgens and progestogens in wastewater treatment plants and receiving river waters: Comparison to estrogens Water Res. 2011, 45 (2) 732-740
    • (2011) Water Res. , vol.45 , Issue.2 , pp. 732-740
    • Chang, H.1    Wan, Y.2    Wu, S.3    Fan, Z.4    Hu, J.5
  • 118
    • 77950429952 scopus 로고    scopus 로고
    • Therapeutic levels of levonorgestrel detected in blood plasma of fish: Results from screening rainbow trout exposed to treated sewage effluents
    • Fick, J.; Lindberg, R. H.; Parkkonen, J.; Arvidsson, B.; Tysklind, M.; Larsson, D. G. J. Therapeutic levels of levonorgestrel detected in blood plasma of fish: Results from screening rainbow trout exposed to treated sewage effluents Environ. Sci. Technol. 2010, 44 (7) 2661-2666
    • (2010) Environ. Sci. Technol. , vol.44 , Issue.7 , pp. 2661-2666
    • Fick, J.1    Lindberg, R.H.2    Parkkonen, J.3    Arvidsson, B.4    Tysklind, M.5    Larsson, D.G.J.6
  • 119
    • 80052312060 scopus 로고    scopus 로고
    • Screening of pharmaceuticals and hormones at the regional scale, in surface and groundwaters intended to human consumption
    • Vulliet, E.; Cren-Olivé, C. Screening of pharmaceuticals and hormones at the regional scale, in surface and groundwaters intended to human consumption Environ. Pollut. 2011, 159 (10) 2929-2934
    • (2011) Environ. Pollut. , vol.159 , Issue.10 , pp. 2929-2934
    • Vulliet, E.1    Cren-Olivé, C.2
  • 120
    • 53649103349 scopus 로고    scopus 로고
    • Multi-residue analysis of steroids at sub-ng/L levels in surface and ground-waters using liquid chromatography coupled to tandem mass spectrometry
    • Vulliet, E.; Wiest, L.; Baudot, R.; Grenier-Loustalot, M.-F. Multi-residue analysis of steroids at sub-ng/L levels in surface and ground-waters using liquid chromatography coupled to tandem mass spectrometry J. Chromatogr. A 2008, 1210 (1) 84-91
    • (2008) J. Chromatogr. A , vol.1210 , Issue.1 , pp. 84-91
    • Vulliet, E.1    Wiest, L.2    Baudot, R.3    Grenier-Loustalot, M.-F.4
  • 121
    • 77956157233 scopus 로고    scopus 로고
    • High-throughput identification of microbial transformation products of organic micropollutants
    • Helbling, D. E.; Hollender, J.; Kohler, H.-P. E.; Singer, H.; Fenner, K. High-throughput identification of microbial transformation products of organic micropollutants Environ. Sci. Technol. 2010, 44 (17) 6621-6627
    • (2010) Environ. Sci. Technol. , vol.44 , Issue.17 , pp. 6621-6627
    • Helbling, D.E.1    Hollender, J.2    Kohler, H.-P.E.3    Singer, H.4    Fenner, K.5
  • 122
    • 77953476829 scopus 로고    scopus 로고
    • LC-high resolution MS in environmental analysis: From target screening to the identification of unknowns
    • Krauss, M.; Singer, H.; Hollender, J. LC-high resolution MS in environmental analysis: From target screening to the identification of unknowns Anal. Bioanal. Chem. 2010, 397 (3) 943-951
    • (2010) Anal. Bioanal. Chem. , vol.397 , Issue.3 , pp. 943-951
    • Krauss, M.1    Singer, H.2    Hollender, J.3
  • 123
    • 0036784682 scopus 로고    scopus 로고
    • Endocrine disruptors in sewage treatment plants, receiving river waters, and sediments: Integration of chemical analysis and biological effects on feral carp
    • Petrovic, M.; Solé, M.; López De Alda, M. J.; Barceló, D. Endocrine disruptors in sewage treatment plants, receiving river waters, and sediments: Integration of chemical analysis and biological effects on feral carp Environ. Toxicol. Chem. 2002, 21 (10) 2146-2156
    • (2002) Environ. Toxicol. Chem. , vol.21 , Issue.10 , pp. 2146-2156
    • Petrovic, M.1    Solé, M.2    López De Alda, M.J.3    Barceló, D.4
  • 124
    • 20644441779 scopus 로고    scopus 로고
    • Estrogenicity determination in sewage treatment plants and surface waters from the Catalonian area (NE Spain)
    • Sole, M.; de Alda, M.; Castillo, M.; Porte, C.; Ladegaard-Pedersen, K.; Barcelo, D. Estrogenicity determination in sewage treatment plants and surface waters from the Catalonian area (NE Spain) Environ. Sci. Technol. 2000, 34 (24) 5076-5083
    • (2000) Environ. Sci. Technol. , vol.34 , Issue.24 , pp. 5076-5083
    • Sole, M.1    De Alda, M.2    Castillo, M.3    Porte, C.4    Ladegaard-Pedersen, K.5    Barcelo, D.6
  • 125
    • 52949145243 scopus 로고    scopus 로고
    • Trace analysis of contraceptive drug levonorgestrel in wastewater samples by a newly developed indirect competitive enzyme-linked immunosorbent assay (ELISA) coupled with solid phase extraction
    • Pu, C.; Wu, Y.-F.; Yang, H.; Deng, A.-P. Trace analysis of contraceptive drug levonorgestrel in wastewater samples by a newly developed indirect competitive enzyme-linked immunosorbent assay (ELISA) coupled with solid phase extraction Anal. Chim. Acta 2008, 628 (1) 73-79
    • (2008) Anal. Chim. Acta , vol.628 , Issue.1 , pp. 73-79
    • Pu, C.1    Wu, Y.-F.2    Yang, H.3    Deng, A.-P.4
  • 126
    • 70349246397 scopus 로고    scopus 로고
    • Preparation and characterization of an immunoaffinity chromatography column for the selective extraction of trace contraceptive drug levonorgestrel from water samples
    • Qiao, Y.; Yang, H.; Wang, B.; Song, J.; Deng, A. Preparation and characterization of an immunoaffinity chromatography column for the selective extraction of trace contraceptive drug levonorgestrel from water samples Talanta 2009, 80 (1) 98-103
    • (2009) Talanta , vol.80 , Issue.1 , pp. 98-103
    • Qiao, Y.1    Yang, H.2    Wang, B.3    Song, J.4    Deng, A.5
  • 127
    • 0345735762 scopus 로고    scopus 로고
    • All progestins are not created equal
    • Stanczyk, F. Z. All progestins are not created equal Steroids 2003, 68 (10-13) 879-890
    • (2003) Steroids , vol.68 , Issue.1013 , pp. 879-890
    • Stanczyk, F.Z.1
  • 128
    • 0034832754 scopus 로고    scopus 로고
    • Fish cell lines as versatile tools in ecotoxicology: Assessment of cytotoxicity, cytochrome P4501A induction potential and estrogenic activity of chemicals and environmental samples
    • Fent, K. Fish cell lines as versatile tools in ecotoxicology: Assessment of cytotoxicity, cytochrome P4501A induction potential and estrogenic activity of chemicals and environmental samples Toxicol. In Vitro 2001, 15 (4-5) 477-488
    • (2001) Toxicol. in Vitro , vol.15 , Issue.45 , pp. 477-488
    • Fent, K.1
  • 129
    • 40049087300 scopus 로고    scopus 로고
    • Screening of some anti-progestin endocrine disruptors using a recombinant yeast based in vitro bioassay
    • Chatterjee, S.; Kumar, V.; Majumder, C. B.; Roy, P. Screening of some anti-progestin endocrine disruptors using a recombinant yeast based in vitro bioassay Toxicol. In Vitro 2008, 22 (3) 788-798
    • (2008) Toxicol. in Vitro , vol.22 , Issue.3 , pp. 788-798
    • Chatterjee, S.1    Kumar, V.2    Majumder, C.B.3    Roy, P.4
  • 130
    • 0031656115 scopus 로고    scopus 로고
    • Several environmental oestrogens are also anti-androgens
    • Sohoni, P.; Sumpter, J. Several environmental oestrogens are also anti-androgens J. Endocrinol. 1998, 158 (3) 327-339
    • (1998) J. Endocrinol. , vol.158 , Issue.3 , pp. 327-339
    • Sohoni, P.1    Sumpter, J.2
  • 131
    • 0032144287 scopus 로고    scopus 로고
    • Development of a high-throughput in vitro bioassay to assess potencies of progestagenic compounds using Chinese hamster ovary cells stably transfected with the human progesterone receptor and a luciferase reporter system
    • Schoonen, W. G. E. J.; de Ries, R. J. H.; Joosten, J. W. H.; Mathijssen-Mommers, G. J. W.; Kloosterboer, H. J. Development of a high-throughput in vitro bioassay to assess potencies of progestagenic compounds using Chinese hamster ovary cells stably transfected with the human progesterone receptor and a luciferase reporter system Anal. Biochem. 1998, 261 (2) 222-224
    • (1998) Anal. Biochem. , vol.261 , Issue.2 , pp. 222-224
    • Schoonen, W.G.E.J.1    De Ries, R.J.H.2    Joosten, J.W.H.3    Mathijssen-Mommers, G.J.W.4    Kloosterboer, H.J.5
  • 132
    • 48749127971 scopus 로고    scopus 로고
    • Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays
    • van der Linden, S. C.; Heringa, M. B.; Man, H.-Y.; Sonneveld, E.; Puijker, L. M.; Brouwer, A.; van der Burg, B. Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays Environ. Sci. Technol. 2008, 42 (15) 5814-5820
    • (2008) Environ. Sci. Technol. , vol.42 , Issue.15 , pp. 5814-5820
    • Van Der Linden, S.C.1    Heringa, M.B.2    Man, H.-Y.3    Sonneveld, E.4    Puijker, L.M.5    Brouwer, A.6    Van Der Burg, B.7
  • 133
    • 84908402413 scopus 로고    scopus 로고
    • Assessment of multiple hormonal activities in wastewater at different stages of treatment
    • Bain, P. A.; Williams, M.; Kumar, A. Assessment of multiple hormonal activities in wastewater at different stages of treatment Environ. Toxicol. Chem. 2014, 33 (10) 2297-2307
    • (2014) Environ. Toxicol. Chem. , vol.33 , Issue.10 , pp. 2297-2307
    • Bain, P.A.1    Williams, M.2    Kumar, A.3
  • 134
    • 33847684354 scopus 로고    scopus 로고
    • Analytical methods for the determination of selected steroid sex hormones and corticosteriods in wastewater
    • Vulliet, E.; Baugros, J.-B.; Flament-Waton, M.-M.; Grenier-Loustalot, M.-F. Analytical methods for the determination of selected steroid sex hormones and corticosteriods in wastewater Anal. Bioanal. Chem. 2007, 387 (6) 2143-2151
    • (2007) Anal. Bioanal. Chem. , vol.387 , Issue.6 , pp. 2143-2151
    • Vulliet, E.1    Baugros, J.-B.2    Flament-Waton, M.-M.3    Grenier-Loustalot, M.-F.4
  • 135
    • 70450016380 scopus 로고    scopus 로고
    • Determination and source apportionment of five classes of steroid hormones in urban rivers
    • Chang, H.; Wan, Y.; Hu, J. Determination and source apportionment of five classes of steroid hormones in urban rivers Environ. Sci. Technol. 2009, 43 (20) 7691-7698
    • (2009) Environ. Sci. Technol. , vol.43 , Issue.20 , pp. 7691-7698
    • Chang, H.1    Wan, Y.2    Hu, J.3
  • 136
    • 84884407678 scopus 로고    scopus 로고
    • Occurrence, fate and environmental risk assessment of endocrine disrupting compounds at the wastewater treatment works in Pietermaritzburg (South Africa)
    • Manickum, T.; John, W. Occurrence, fate and environmental risk assessment of endocrine disrupting compounds at the wastewater treatment works in Pietermaritzburg (South Africa) Sci. Total Environ. 2014, 468-469, 584-597
    • (2014) Sci. Total Environ. , vol.468-469 , pp. 584-597
    • Manickum, T.1    John, W.2
  • 137
    • 84864120797 scopus 로고    scopus 로고
    • Fate and occurrence of steroids in swine and dairy cattle farms with different farming scales and wastes disposal systems
    • Liu, S.; Ying, G.-G.; Zhang, R.-Q.; Zhou, L.-J.; Lai, H.-J.; Chen, Z.-F. Fate and occurrence of steroids in swine and dairy cattle farms with different farming scales and wastes disposal systems Environ. Pollut. 2012, 170, 190-201
    • (2012) Environ. Pollut. , vol.170 , pp. 190-201
    • Liu, S.1    Ying, G.-G.2    Zhang, R.-Q.3    Zhou, L.-J.4    Lai, H.-J.5    Chen, Z.-F.6
  • 138
    • 0038324428 scopus 로고    scopus 로고
    • Androstenedione and progesterone in the sediment of a river receiving paper mill effluent
    • Jenkins, R. L.; Wilson, E. M.; Angus, R. A.; Howell, W. M.; Kirk, M. Androstenedione and progesterone in the sediment of a river receiving paper mill effluent Toxicol. Sci. 2003, 73 (1) 53-59
    • (2003) Toxicol. Sci. , vol.73 , Issue.1 , pp. 53-59
    • Jenkins, R.L.1    Wilson, E.M.2    Angus, R.A.3    Howell, W.M.4    Kirk, M.5
  • 139
    • 77957683227 scopus 로고    scopus 로고
    • Multi-residue analytical method for human pharmaceuticals and synthetic hormones in river water and sewage effluents by solid-phase extraction and liquid chromatography-tandem mass spectrometry
    • Al-Odaini, N. A.; Zakaria, M. P.; Yaziz, M. I.; Surif, S. Multi-residue analytical method for human pharmaceuticals and synthetic hormones in river water and sewage effluents by solid-phase extraction and liquid chromatography-tandem mass spectrometry J. Chromatogr. A 2010, 1217 (44) 6791-6806
    • (2010) J. Chromatogr. A , vol.1217 , Issue.44 , pp. 6791-6806
    • Al-Odaini, N.A.1    Zakaria, M.P.2    Yaziz, M.I.3    Surif, S.4
  • 140
    • 22344438853 scopus 로고    scopus 로고
    • Determination of steroidal hormone profiles along the Jalle d'Eysines river (near Bordeaux, France)
    • Labadie, P.; Budzinski, H. Determination of steroidal hormone profiles along the Jalle d'Eysines river (near Bordeaux, France) Environ. Sci. Technol. 2005, 39 (14) 5113-5120
    • (2005) Environ. Sci. Technol. , vol.39 , Issue.14 , pp. 5113-5120
    • Labadie, P.1    Budzinski, H.2
  • 141
    • 77955924403 scopus 로고    scopus 로고
    • The use of modelling to predict levels of estrogens in a river catchment: How does modelled data compare with chemical analysis and in vitro yeast assay results?
    • Balaam, J. L.; Grover, D.; Johnson, A. C.; Jürgens, M.; Readman, J.; Smith, A. J.; White, S.; Williams, R.; Zhou, J. L. The use of modelling to predict levels of estrogens in a river catchment: How does modelled data compare with chemical analysis and in vitro yeast assay results? Sci. Total Environ. 2010, 408 (20) 4826-4832
    • (2010) Sci. Total Environ. , vol.408 , Issue.20 , pp. 4826-4832
    • Balaam, J.L.1    Grover, D.2    Johnson, A.C.3    Jürgens, M.4    Readman, J.5    Smith, A.J.6    White, S.7    Williams, R.8    Zhou, J.L.9
  • 142
    • 84862808446 scopus 로고    scopus 로고
    • Comparing predicted against measured steroid estrogen concentrations and the associated risk in two United Kingdom river catchments
    • Williams, R. J.; Churchley, J. H.; Kanda, R.; Johnson, A. C. Comparing predicted against measured steroid estrogen concentrations and the associated risk in two United Kingdom river catchments Environ. Toxicol. Chem. 2012, 31 (4) 892-898
    • (2012) Environ. Toxicol. Chem. , vol.31 , Issue.4 , pp. 892-898
    • Williams, R.J.1    Churchley, J.H.2    Kanda, R.3    Johnson, A.C.4
  • 143
    • 84887986258 scopus 로고    scopus 로고
    • Do Concentrations of ethinylestradiol, estradiol, and diclofenac in European rivers exceed proposed EU environmental quality standards?
    • Johnson, A. C.; Dumont, E.; Williams, R. J.; Oldenkamp, R.; Cisowska, I.; Sumpter, J. P. Do Concentrations of ethinylestradiol, estradiol, and diclofenac in European rivers exceed proposed EU environmental quality standards? Environ. Sci. Technol. 2013, 47 (21) 12297-12304
    • (2013) Environ. Sci. Technol. , vol.47 , Issue.21 , pp. 12297-12304
    • Johnson, A.C.1    Dumont, E.2    Williams, R.J.3    Oldenkamp, R.4    Cisowska, I.5    Sumpter, J.P.6
  • 145
    • 84892488766 scopus 로고    scopus 로고
    • Worldwide estimation of river concentrations of any chemical originating from sewage-treatment plants using dilution factors
    • Keller, V. D. J.; Williams, R. J.; Lofthouse, C.; Johnson, A. C. Worldwide estimation of river concentrations of any chemical originating from sewage-treatment plants using dilution factors Environ. Toxicol. Chem. 2014, 33 (2) 447-452
    • (2014) Environ. Toxicol. Chem. , vol.33 , Issue.2 , pp. 447-452
    • Keller, V.D.J.1    Williams, R.J.2    Lofthouse, C.3    Johnson, A.C.4
  • 146
    • 84856955505 scopus 로고    scopus 로고
    • Tissue-specific uptake and bioconcentration of the oral contraceptive norethindrone in two freshwater fishes
    • Nallani, G.; Paulos, P.; Venables, B.; Edziyie, R.; Constantine, L.; Huggett, D. Tissue-specific uptake and bioconcentration of the oral contraceptive norethindrone in two freshwater fishes Arch. Environ. Contam. Toxicol. 2012, 62 (2) 306-313
    • (2012) Arch. Environ. Contam. Toxicol. , vol.62 , Issue.2 , pp. 306-313
    • Nallani, G.1    Paulos, P.2    Venables, B.3    Edziyie, R.4    Constantine, L.5    Huggett, D.6
  • 147
    • 84886309515 scopus 로고    scopus 로고
    • Tissue-specific bioconcentration of the synthetic steroid hormone medroxyprogesterone acetate in the common carp (Cyprinus carpio)
    • Steele, W. B., IV; Garcia, S. N.; Huggett, D. B.; Venables, B. J.; Barnes, S. E., III; La Point, T. W. Tissue-specific bioconcentration of the synthetic steroid hormone medroxyprogesterone acetate in the common carp (Cyprinus carpio) Environ. Toxicol. Pharmacol. 2013, 36 (3) 1120-1126
    • (2013) Environ. Toxicol. Pharmacol. , vol.36 , Issue.3 , pp. 1120-1126
    • Steele, W.B.I.V.1    Garcia, S.N.2    Huggett, D.B.3    Venables, B.J.4    Barnes, S.E.5    La Point, T.W.6
  • 148
    • 79951831415 scopus 로고    scopus 로고
    • Predicted critical environmental concentrations for 500 pharmaceuticals
    • Fick, J.; Lindberg, R. H.; Tysklind, M.; Larsson, D. G. J. Predicted critical environmental concentrations for 500 pharmaceuticals Regul. Toxicol. Pharmacol. 2010, 58 (3) 516-523
    • (2010) Regul. Toxicol. Pharmacol. , vol.58 , Issue.3 , pp. 516-523
    • Fick, J.1    Lindberg, R.H.2    Tysklind, M.3    Larsson, D.G.J.4
  • 150
    • 0035501759 scopus 로고    scopus 로고
    • Branchial elimination of superhydrophobic organic compounds by rainbow trout (Oncorhynchus mykiss)
    • Fitzsimmons, P. N.; Fernandez, J. D.; Hoffman, A. D.; Butterworth, B. C.; Nichols, J. W. Branchial elimination of superhydrophobic organic compounds by rainbow trout (Oncorhynchus mykiss) Aquat. Toxicol. 2001, 55 (1-2) 23-34
    • (2001) Aquat. Toxicol. , vol.55 , Issue.12 , pp. 23-34
    • Fitzsimmons, P.N.1    Fernandez, J.D.2    Hoffman, A.D.3    Butterworth, B.C.4    Nichols, J.W.5
  • 151
    • 2342652328 scopus 로고    scopus 로고
    • A theoretical model for utilizing mammalian pharmacology and safety data to prioritize potential impacts of human pharmaceuticals to fish
    • Huggett, D. B.; Cook, J. C.; Ericson, J. F.; Williams, R. T. A theoretical model for utilizing mammalian pharmacology and safety data to prioritize potential impacts of human pharmaceuticals to fish Hum. Ecol. Risk Assess. 2003, 9 (7) 1789-1799
    • (2003) Hum. Ecol. Risk Assess. , vol.9 , Issue.7 , pp. 1789-1799
    • Huggett, D.B.1    Cook, J.C.2    Ericson, J.F.3    Williams, R.T.4
  • 152
    • 74249103600 scopus 로고    scopus 로고
    • Bioequivalence study of generic tablet formulations containing ethinylestradiol and chlormadinone acetate in healthy female volunteers
    • Bonn, M.; Eydeler, U.; Barkworth, M.; Rovati, L. C. Bioequivalence study of generic tablet formulations containing ethinylestradiol and chlormadinone acetate in healthy female volunteers Arzneimittelforschung 2009, 59 (12) 651-658
    • (2009) Arzneimittelforschung , vol.59 , Issue.12 , pp. 651-658
    • Bonn, M.1    Eydeler, U.2    Barkworth, M.3    Rovati, L.C.4
  • 154
    • 84872168470 scopus 로고    scopus 로고
    • Pharmacokinetic profile of nomegestrol acetate and 17β-estradiol after multiple and single dosing in healthy women
    • Gerrits, M. G. F.; Schnabel, P. G.; Post, T. M.; Peeters, P. A. M. Pharmacokinetic profile of nomegestrol acetate and 17β-estradiol after multiple and single dosing in healthy women Contraception 2013, 87 (2) 193-200
    • (2013) Contraception , vol.87 , Issue.2 , pp. 193-200
    • Gerrits, M.G.F.1    Schnabel, P.G.2    Post, T.M.3    Peeters, P.A.M.4
  • 155
    • 0032790548 scopus 로고    scopus 로고
    • Parenteral administration of progestin Nestorone to lactating cynomolgus monkeys: An ideal hormonal contraceptive at lactation?
    • Heikinheimo, O.; Ranta, S.; Moo-Young, A.; Lähteenmäki, P.; Gordon, K. Parenteral administration of progestin Nestorone to lactating cynomolgus monkeys: An ideal hormonal contraceptive at lactation? Hum. Reprod. 1999, 14 (8) 1993-1997
    • (1999) Hum. Reprod. , vol.14 , Issue.8 , pp. 1993-1997
    • Heikinheimo, O.1    Ranta, S.2    Moo-Young, A.3    Lähteenmäki, P.4    Gordon, K.5
  • 156
    • 33644767887 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between bosentan and the oral contraceptives norethisterone and ethinyl estradiol
    • Van Giersbergen, P. L. M.; Halabi, A.; Dingemanse, J. Pharmacokinetic interaction between bosentan and the oral contraceptives norethisterone and ethinyl estradiol Int. J. Clin. Pharmacol. Ther. 2006, 44 (3) 113-118
    • (2006) Int. J. Clin. Pharmacol. Ther. , vol.44 , Issue.3 , pp. 113-118
    • Van Giersbergen, P.L.M.1    Halabi, A.2    Dingemanse, J.3
  • 157
    • 0021795686 scopus 로고
    • Norethisterone concentration in breast milk and infant and maternal plasma during ethynodiol diacetate administration
    • Cooke, I. D.; Back, D. J.; Shroff, N. E. Norethisterone concentration in breast milk and infant and maternal plasma during ethynodiol diacetate administration Contraception 1985, 31 (6) 611-621
    • (1985) Contraception , vol.31 , Issue.6 , pp. 611-621
    • Cooke, I.D.1    Back, D.J.2    Shroff, N.E.3
  • 158
    • 0035459218 scopus 로고    scopus 로고
    • Transfer of drospirenone to breast milk after a single oral administration of 3 mg drospirenone + 30 μg ethinylestradiol to healthy lactating women
    • Blode, H.; Foidart, J. M.; Heithecker, R. Transfer of drospirenone to breast milk after a single oral administration of 3 mg drospirenone + 30 μg ethinylestradiol to healthy lactating women Eur. J. Contracept. Reprod. Health Care 2001, 6 (3) 167-171
    • (2001) Eur. J. Contracept. Reprod. Health Care , vol.6 , Issue.3 , pp. 167-171
    • Blode, H.1    Foidart, J.M.2    Heithecker, R.3
  • 159
    • 78149285097 scopus 로고    scopus 로고
    • The influence of gill and liver metabolism on the predicted bioconcentration of three pharmaceuticals in fish
    • Gomez, C. F.; Constantine, L.; Huggett, D. B. The influence of gill and liver metabolism on the predicted bioconcentration of three pharmaceuticals in fish Chemosphere 2010, 81 (10) 1189-1195
    • (2010) Chemosphere , vol.81 , Issue.10 , pp. 1189-1195
    • Gomez, C.F.1    Constantine, L.2    Huggett, D.B.3


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