Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 2. Gene expression analysis and in vitro activity

Aquatic Toxicology

Volumn 144-145, Issue , 2013, Pages 96-104

  Blüthgen, Nancy ^a,b   Sumpter, John P ^c   Odermatt, Alex ^b   Fent, Karl ^a,d  

^a UNIVERSITY OF APPLIED SCIENCES AND ARTS NORTHWESTERN SWITZERLAND   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c BRUNEL UNIVERSITY   (United Kingdom)

^d ETH ZURICH   (Switzerland)

Author keywords

Antiprogestin; Gene expression; In vitro hormonal activity; Mifepristone; Progesterone; Recombinant yeast system; RU486

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ANDROGEN RECEPTOR; AROMATASE; ESTROGEN RECEPTOR; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE; PROGESTERONE RECEPTOR; STEROID 11BETA MONOOXYGENASE; VITELLOGENIN;

ADULT; BIOACCUMULATION; DRUG; EMBRYO; FISH; GENE EXPRESSION; HISTOLOGY; POLLUTION EFFECT; REPRODUCTION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AR GENE; ARTICLE; CONTROLLED STUDY; CYB11B GENE; CYP19A GENE; EMBRYO; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOTOXICITY; GR GENE; HISTOPATHOLOGY; HSD17B3 GENE; HSD3B GENE; IN VITRO STUDY; IN VIVO STUDY; LONG TERM EXPOSURE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PGR GENE; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; TOXICITY TESTING; TRANSCRIPTION REGULATION; VTG1 GENE; ZEBRA FISH;

ANTIPROGESTIN; GENE EXPRESSION; IN VITRO HORMONAL ACTIVITY; MIFEPRISTONE; PROGESTERONE; RECOMBINANT YEAST SYSTEM; RU486;

ANIMALS; FEMALE; GENE EXPRESSION REGULATION; MALE; MIFEPRISTONE; VITELLOGENINS; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

EID: 84886233028     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2013.09.030     Document Type: Article

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