The synthetic gestagen levonorgestrel impairs metamorphosis in xenopus laevis by disruption of the thyroid system

Toxicological Sciences

Volumn 123, Issue 1, 2011, Pages 94-102

  Lorenz, Claudia ^a   Contardo Jara, Valeska ^a,b   Pflugmacher, Stephan ^a,b   Wiegand, Claudia ^c   Nützmann, Gunnar ^a   Lutz, Ilka ^a   Kloas, Werner ^a,d  

^a LEIBNIZ INSTITUTE OF FRESHWATER ECOLOGY AND INLAND FISHERIES   (Germany)

^b TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Amphibian metamorphosis assay; Progestin; Prolactin; Thyroid histology; Thyroid stimulating hormone; Xenopus laevis

Indexed keywords

LEVONORGESTREL; MESSENGER RNA; PROLACTIN; THYROID HORMONE; THYROID HORMONE RECEPTOR BETA; THYROTROPIN BETA SUBUNIT;

ARTICLE; BRAIN; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HYPOPHYSIS THYROID SYSTEM; MALE; METAMORPHOSIS; NEUROHYPOPHYSIS; NONHUMAN; TADPOLE; XENOPUS LAEVIS;

ANIMALS; BRAIN; CONTRACEPTIVE AGENTS, FEMALE; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH AND DEVELOPMENT; LARVA; LEVONORGESTREL; LONGEVITY; MALE; PITUITARY GLAND; THYROID GLAND; THYROTROPIN, BETA SUBUNIT; TIME FACTORS; XENOPUS LAEVIS;

AMPHIBIA; ASCAPHUS TRUEI; XENOPUS LAEVIS;

EID: 80052462254     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr159     Document Type: Article

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