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Volumn 5, Issue APR, 2014, Pages

The role of pregnancy-associated hormones in the development and function of regulatory B cells

Author keywords

Autoimmune diseases; Estradiol; Female hormones; HCG; Pregnancy; Regulatory B cells

Indexed keywords

CHORIONIC GONADOTROPIN; ESTRADIOL; ESTRADIOL RECEPTOR; INTERLEUKIN 10; PROGESTERONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84901011405     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2014.00039     Document Type: Short Survey
Times cited : (51)

References (48)
  • 1
    • 31144467556 scopus 로고    scopus 로고
    • Endocrinology of recurrent pregnancy loss
    • doi:10.1055/s-2006-931799
    • Arredond F, Noble LS. Endocrinology of recurrent pregnancy loss. Semin Reprod Med (2006) 24:33-9. doi:10.1055/s-2006-931799.
    • (2006) Semin Reprod Med , vol.24 , pp. 33-39
    • Arredond, F.1    Noble, L.S.2
  • 3
    • 18644366006 scopus 로고    scopus 로고
    • HCG increases trophoblast migration in vitro via the insulin-like growth factor-II/mannose-6 phosphate receptor
    • doi:10.1093/molehr/gah160
    • Zygmunt M, McKinnon T, Herr F, Lala PK, Han VKM. HCG increases trophoblast migration in vitro via the insulin-like growth factor-II/mannose-6 phosphate receptor. Mol Hum Reprod (2005) 11:261-7. doi:10.1093/molehr/gah160.
    • (2005) Mol Hum Reprod , vol.11 , pp. 261-267
    • Zygmunt, M.1    McKinnon, T.2    Herr, F.3    Lala, P.K.4    Han, V.K.M.5
  • 4
    • 0142124417 scopus 로고    scopus 로고
    • Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone
    • doi:10.1016/S0928-8244(03)00202-5
    • Beagley KW, Gockel CM. Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone. FEMS Immunol Med Microbiol (2003) 38:13-22. doi:10.1016/S0928-8244(03)00202-5.
    • (2003) FEMS Immunol Med Microbiol , vol.38 , pp. 13-22
    • Beagley, K.W.1    Gockel, C.M.2
  • 5
    • 1542287265 scopus 로고    scopus 로고
    • Regulatory T cells mediate maternal tolerance to the fetus
    • doi:10.1038/ni1037
    • Aluvihare VR, Kallikourdis M, Betz AG. Regulatory T cells mediate maternal tolerance to the fetus. Nat Immunol (2004) 5:266-71. doi:10.1038/ni1037.
    • (2004) Nat Immunol , vol.5 , pp. 266-271
    • Aluvihare, V.R.1    Kallikourdis, M.2    Betz, A.G.3
  • 6
    • 57349108583 scopus 로고    scopus 로고
    • Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero
    • doi:10.1126/science.1164511
    • Mold JE, Michaëlsson J, Burt TD, Muench MO, Beckerman KP, Busch MP, et al. Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. Science (2008) 322:1562-5. doi:10.1126/science.1164511.
    • (2008) Science , vol.322 , pp. 1562-1565
    • Mold, J.E.1    Michaëlsson, J.2    Burt, T.D.3    Muench, M.O.4    Beckerman, K.P.5    Busch, M.P.6
  • 7
    • 0016342561 scopus 로고
    • B-cell suppression of delayed hypersensitivity reactions
    • doi:10.1038/251550a0
    • Katz SI, Parker D, Turk JL. B-cell suppression of delayed hypersensitivity reactions. Nature (1974) 251:550-1. doi:10.1038/251550a0.
    • (1974) Nature , vol.251 , pp. 550-551
    • Katz, S.I.1    Parker, D.2    Turk, J.L.3
  • 8
    • 0016292553 scopus 로고
    • Specific suppression of delayed hypersensitivity: the possible presence of a suppressor B cell in the regulation of delayed hypersensitivity
    • Neta R, Salvin SB. Specific suppression of delayed hypersensitivity: the possible presence of a suppressor B cell in the regulation of delayed hypersensitivity. J Immunol (1974) 113:1716-25.
    • (1974) J Immunol , vol.113 , pp. 1716-1725
    • Neta, R.1    Salvin, S.B.2
  • 9
    • 0030456897 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice
    • doi:10.1084/jem.184.6.2271
    • Wolf SD, Dittel BN, Hardardottir F, Janeway CA. Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J Exp Med (1996) 184:2271-8. doi:10.1084/jem.184.6.2271.
    • (1996) J Exp Med , vol.184 , pp. 2271-2278
    • Wolf, S.D.1    Dittel, B.N.2    Hardardottir, F.3    Janeway, C.A.4
  • 12
    • 43049156086 scopus 로고    scopus 로고
    • A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses
    • doi:10.1016/j.immuni.2008.03.017
    • Yanaba K, Bouaziz J, Haas KM, Poe JC, Fujimoto M, Tedder TF. A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. Immunity (2008) 28:639-50. doi:10.1016/j.immuni.2008.03.017.
    • (2008) Immunity , vol.28 , pp. 639-650
    • Yanaba, K.1    Bouaziz, J.2    Haas, K.M.3    Poe, J.C.4    Fujimoto, M.5    Tedder, T.F.6
  • 13
    • 74649083783 scopus 로고    scopus 로고
    • CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients
    • doi:10.1016/j.immuni.2009.11.009
    • Blair PA, Noreña LY, Flores-Borja F, Rawlings DJ, Isenberg DA, Ehrenstein MR, et al. CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients. Immunity (2010) 32:129-40. doi:10.1016/j.immuni.2009.11.009.
    • (2010) Immunity , vol.32 , pp. 129-140
    • Blair, P.A.1    Noreña, L.Y.2    Flores-Borja, F.3    Rawlings, D.J.4    Isenberg, D.A.5    Ehrenstein, M.R.6
  • 14
    • 78751469622 scopus 로고    scopus 로고
    • Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells
    • doi:10.1182/blood-2010-07-294249
    • Iwata Y, Matsushita T, Horikawa M, Dilillo DJ, Yanaba K, Venturi GM, et al. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood (2011) 117:530-41. doi:10.1182/blood-2010-07-294249.
    • (2011) Blood , vol.117 , pp. 530-541
    • Iwata, Y.1    Matsushita, T.2    Horikawa, M.3    Dilillo, D.J.4    Yanaba, K.5    Venturi, G.M.6
  • 15
    • 0029017478 scopus 로고
    • IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau
    • Chaouat G, Assal Meliani A, Martal J, Raghupathy R, Elliott JF, Elliot J, et al. IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau. J Immunol (1995) 154:4261-8.
    • (1995) J Immunol , vol.154 , pp. 4261-4268
    • Chaouat, G.1    Assal Meliani, A.2    Martal, J.3    Raghupathy, R.4    Elliott, J.F.5    Elliot, J.6
  • 16
    • 84898943318 scopus 로고    scopus 로고
    • Regulatory B10 cells restore pregnancy tolerance in a mouse model
    • doi:10.1095/biolreprod.113.110791
    • Jensen F, Muzzio D, Soldati R, Fest S, Zenclussen AC. Regulatory B10 cells restore pregnancy tolerance in a mouse model. Biol Reprod (2013) 89:90. doi:10.1095/biolreprod.113.110791.
    • (2013) Biol Reprod , vol.89 , pp. 90
    • Jensen, F.1    Muzzio, D.2    Soldati, R.3    Fest, S.4    Zenclussen, A.C.5
  • 18
    • 0031240055 scopus 로고    scopus 로고
    • Epidemiology and estimated population burden of selected autoimmune diseases in the United States
    • doi:10.1006/clin.1997.4412
    • Jacobson DL, Gange SJ, Rose NR, Graham NM. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin Immunol Immunopathol (1997) 84:223-43. doi:10.1006/clin.1997.4412.
    • (1997) Clin Immunol Immunopathol , vol.84 , pp. 223-243
    • Jacobson, D.L.1    Gange, S.J.2    Rose, N.R.3    Graham, N.M.4
  • 19
    • 33847083891 scopus 로고    scopus 로고
    • Gender as risk factor for autoimmune diseases
    • doi:10.1016/j.jaut.2006.12.004
    • Gleicher N, Barad DH. Gender as risk factor for autoimmune diseases. J Autoimmun (2007) 28:1-6. doi:10.1016/j.jaut.2006.12.004.
    • (2007) J Autoimmun , vol.28 , pp. 1-6
    • Gleicher, N.1    Barad, D.H.2
  • 20
    • 84879236067 scopus 로고    scopus 로고
    • New-onset systemic lupus erythematosus during pregnancy
    • doi:10.1007/s10067-013-2180-z
    • Zhao C, Zhao J, Huang Y, Wang Z, Wang H, Zhang H, et al. New-onset systemic lupus erythematosus during pregnancy. Clin Rheumatol (2013) 32:815-22. doi:10.1007/s10067-013-2180-z.
    • (2013) Clin Rheumatol , vol.32 , pp. 815-822
    • Zhao, C.1    Zhao, J.2    Huang, Y.3    Wang, Z.4    Wang, H.5    Zhang, H.6
  • 21
    • 85028095607 scopus 로고    scopus 로고
    • Pregnancy complicating systemic lupus erythematosus: a series of 86 cases
    • doi:10.1007/s00404-010-1786-5
    • Wei Q, Ouyang Y, Zeng W, Duan L, Ge J, Liao H. Pregnancy complicating systemic lupus erythematosus: a series of 86 cases. Arch Gynecol Obstet (2011) 284:1067-71. doi:10.1007/s00404-010-1786-5.
    • (2011) Arch Gynecol Obstet , vol.284 , pp. 1067-1071
    • Wei, Q.1    Ouyang, Y.2    Zeng, W.3    Duan, L.4    Ge, J.5    Liao, H.6
  • 22
    • 0026571851 scopus 로고
    • Timing of pregnancy in relation to the onset of rheumatoid arthritis
    • doi:10.1002/art.1780350205
    • Silman A, Kay A, Brennan P. Timing of pregnancy in relation to the onset of rheumatoid arthritis. Arthritis Rheum (1992) 35:152-5. doi:10.1002/art.1780350205.
    • (1992) Arthritis Rheum , vol.35 , pp. 152-155
    • Silman, A.1    Kay, A.2    Brennan, P.3
  • 23
    • 0031916977 scopus 로고    scopus 로고
    • The luteinizing hormone receptor
    • doi:10.1146/annurev.physiol.60.1.461
    • Dufau ML. The luteinizing hormone receptor. Annu Rev Physiol (1998) 60:461-96. doi:10.1146/annurev.physiol.60.1.461.
    • (1998) Annu Rev Physiol , vol.60 , pp. 461-496
    • Dufau, M.L.1
  • 24
    • 34548501744 scopus 로고    scopus 로고
    • Human chorionic gonadotropin is an immune modulator and can prevent autoimmune diabetes in NOD mice
    • doi:10.1007/s00125-007-0769-y
    • Khil L, Jun H, Kwon H, Yoo JK, Kim S, Notkins AL, et al. Human chorionic gonadotropin is an immune modulator and can prevent autoimmune diabetes in NOD mice. Diabetologia (2007) 50:2147-55. doi:10.1007/s00125-007-0769-y.
    • (2007) Diabetologia , vol.50 , pp. 2147-2155
    • Khil, L.1    Jun, H.2    Kwon, H.3    Yoo, J.K.4    Kim, S.5    Notkins, A.L.6
  • 25
    • 42949102074 scopus 로고    scopus 로고
    • The effect of trophoblasts on T lymphocytes: possible regulatory effector molecules-a proteomic analysis
    • doi:10.1159/000129639
    • Dong M, Ding G, Zhou J, Wang H, Zhao Y, Huang H. The effect of trophoblasts on T lymphocytes: possible regulatory effector molecules-a proteomic analysis. Cell Physiol Biochem (2008) 21:463-72. doi:10.1159/000129639.
    • (2008) Cell Physiol Biochem , vol.21 , pp. 463-472
    • Dong, M.1    Ding, G.2    Zhou, J.3    Wang, H.4    Zhao, Y.5    Huang, H.6
  • 26
    • 0018958265 scopus 로고
    • In vitro induction of murine suppressor T-cells by human chorionic gonadotropin
    • doi:10.3109/00016348009154093
    • Fuchs T, Hammarström L, Smith CI, Brundin J. In vitro induction of murine suppressor T-cells by human chorionic gonadotropin. Acta Obstet Gynecol Scand (1980) 59:355-9. doi:10.3109/00016348009154093.
    • (1980) Acta Obstet Gynecol Scand , vol.59 , pp. 355-359
    • Fuchs, T.1    Hammarström, L.2    Smith, C.I.3    Brundin, J.4
  • 27
    • 66649135262 scopus 로고    scopus 로고
    • Proliferation of uterine natural killer cells is induced by human chorionic gonadotropin and mediated via the mannose receptor
    • doi:10.1210/en.2008-1309
    • Kane N, Kelly R, Saunders PTK, Critchley HOD. Proliferation of uterine natural killer cells is induced by human chorionic gonadotropin and mediated via the mannose receptor. Endocrinology (2009) 150:2882-8. doi:10.1210/en.2008-1309.
    • (2009) Endocrinology , vol.150 , pp. 2882-2888
    • Kane, N.1    Kelly, R.2    Saunders, P.T.K.3    Critchley, H.O.D.4
  • 29
    • 0042931246 scopus 로고    scopus 로고
    • Human chorionic gonadotropin contributes to maternal immunotolerance and endometrial apoptosis by regulating Fas-Fas ligand system
    • Kayisli UA, Selam B, Guzeloglu-Kayisli O, Demir R, Arici A. Human chorionic gonadotropin contributes to maternal immunotolerance and endometrial apoptosis by regulating Fas-Fas ligand system. J Immunol (2003) 171:2305-13.
    • (2003) J Immunol , vol.171 , pp. 2305-2313
    • Kayisli, U.A.1    Selam, B.2    Guzeloglu-Kayisli, O.3    Demir, R.4    Arici, A.5
  • 30
    • 84874509735 scopus 로고    scopus 로고
    • Pregnancy and multiple sclerosis: feto-maternal immune cross talk and its implications for disease activity
    • doi:10.1016/j.jri.2012.10.005
    • Patas K, Engler JB, Friese MA, Gold SM. Pregnancy and multiple sclerosis: feto-maternal immune cross talk and its implications for disease activity. J Reprod Immunol (2013) 97:140-6. doi:10.1016/j.jri.2012.10.005.
    • (2013) J Reprod Immunol , vol.97 , pp. 140-146
    • Patas, K.1    Engler, J.B.2    Friese, M.A.3    Gold, S.M.4
  • 31
    • 79251602666 scopus 로고    scopus 로고
    • Oestrogen-mediated protection of experimental autoimmune encephalomyelitis in the absence of Foxp3+ regulatory T cells implicates compensatory pathways including regulatory B cells
    • doi:10.1111/j.1365-2567.2010.03380.x
    • Subramanian S, Yates M, Vandenbark AA, Offner H. Oestrogen-mediated protection of experimental autoimmune encephalomyelitis in the absence of Foxp3+ regulatory T cells implicates compensatory pathways including regulatory B cells. Immunology (2011) 132:340-7. doi:10.1111/j.1365-2567.2010.03380.x.
    • (2011) Immunology , vol.132 , pp. 340-347
    • Subramanian, S.1    Yates, M.2    Vandenbark, A.A.3    Offner, H.4
  • 32
    • 54949141219 scopus 로고    scopus 로고
    • Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression
    • doi:10.1172/JCI36030
    • Matsushita T, Yanaba K, Bouaziz J, Fujimoto M, Tedder TF. Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. J Clin Invest (2008) 118:3420-30. doi:10.1172/JCI36030.
    • (2008) J Clin Invest , vol.118 , pp. 3420-3430
    • Matsushita, T.1    Yanaba, K.2    Bouaziz, J.3    Fujimoto, M.4    Tedder, T.F.5
  • 33
    • 72749096461 scopus 로고    scopus 로고
    • B cells from glatiramer acetate-treated mice suppress experimental autoimmune encephalomyelitis
    • doi:10.1016/j.expneurol.2009.10.015
    • Kala M, Rhodes SN, Piao W, Shi F, Campagnolo DI, Vollmer TL. B cells from glatiramer acetate-treated mice suppress experimental autoimmune encephalomyelitis. Exp Neurol (2010) 221:136-45. doi:10.1016/j.expneurol.2009.10.015.
    • (2010) Exp Neurol , vol.221 , pp. 136-145
    • Kala, M.1    Rhodes, S.N.2    Piao, W.3    Shi, F.4    Campagnolo, D.I.5    Vollmer, T.L.6
  • 34
    • 1642332240 scopus 로고    scopus 로고
    • Estrogen signaling: a subtle balance between ER alpha and ER beta
    • doi:10.1124/mi.3.5.281
    • Matthews J, Gustafsson J. Estrogen signaling: a subtle balance between ER alpha and ER beta. Mol Interv (2003) 3:281-92. doi:10.1124/mi.3.5.281.
    • (2003) Mol Interv , vol.3 , pp. 281-292
    • Matthews, J.1    Gustafsson, J.2
  • 35
    • 0141760337 scopus 로고    scopus 로고
    • The protective effect of 17beta-estradiol on experimental autoimmune encephalomyelitis is mediated through estrogen receptor-alpha
    • doi:10.1016/S0002-9440(10)63516-X
    • Polanczyk M, Zamora A, Subramanian S, Matejuk A, Hess DL, Blankenhorn EP, et al. The protective effect of 17beta-estradiol on experimental autoimmune encephalomyelitis is mediated through estrogen receptor-alpha. Am J Pathol (2003) 163:1599-605. doi:10.1016/S0002-9440(10)63516-X.
    • (2003) Am J Pathol , vol.163 , pp. 1599-1605
    • Polanczyk, M.1    Zamora, A.2    Subramanian, S.3    Matejuk, A.4    Hess, D.L.5    Blankenhorn, E.P.6
  • 36
    • 0033933590 scopus 로고    scopus 로고
    • Early B-lymphocyte precursors and their regulation by sex steroids
    • doi:10.1111/j.1600-065X.2000.imr017502.x
    • Kincade PW, Medina KL, Payne KJ, Rossi MI, Tudor KS, Yamashita Y, et al. Early B-lymphocyte precursors and their regulation by sex steroids. Immunol Rev (2000) 175:128-37. doi:10.1111/j.1600-065X.2000.imr017502.x.
    • (2000) Immunol Rev , vol.175 , pp. 128-137
    • Kincade, P.W.1    Medina, K.L.2    Payne, K.J.3    Rossi, M.I.4    Tudor, K.S.5    Yamashita, Y.6
  • 37
    • 0035881589 scopus 로고    scopus 로고
    • Cutting edge: expansion and activation of a population of autoreactive marginal zone B cells in a model of estrogen-induced lupus
    • Grimaldi CM, Michael DJ, Diamond B. Cutting edge: expansion and activation of a population of autoreactive marginal zone B cells in a model of estrogen-induced lupus. J Immunol (2001) 167:1886-90.
    • (2001) J Immunol , vol.167 , pp. 1886-1890
    • Grimaldi, C.M.1    Michael, D.J.2    Diamond, B.3
  • 39
    • 79953045436 scopus 로고    scopus 로고
    • Estrogen-induced protection against experimental autoimmune encephalomyelitis is abrogated in the absence of B cells
    • doi:10.1002/eji.201040992
    • Bodhankar S, Wang C, Vandenbark AA, Offner H. Estrogen-induced protection against experimental autoimmune encephalomyelitis is abrogated in the absence of B cells. Eur J Immunol (2011) 41:1165-75. doi:10.1002/eji.201040992.
    • (2011) Eur J Immunol , vol.41 , pp. 1165-1175
    • Bodhankar, S.1    Wang, C.2    Vandenbark, A.A.3    Offner, H.4
  • 40
    • 0029115517 scopus 로고
    • Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities
    • doi:10.1101/gad.9.18.2266
    • Lydon JP, DeMayo FJ, Funk CR, Mani SK, Hughes AR, Montgomery CA, et al. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev (1995) 9:2266-78. doi:10.1101/gad.9.18.2266.
    • (1995) Genes Dev , vol.9 , pp. 2266-2278
    • Lydon, J.P.1    DeMayo, F.J.2    Funk, C.R.3    Mani, S.K.4    Hughes, A.R.5    Montgomery, C.A.6
  • 41
    • 33847372926 scopus 로고    scopus 로고
    • Progesterone inhibits mature rat dendritic cells in a receptor-mediated fashion
    • doi:10.1093/intimm/dxl145
    • Butts CL, Shukair SA, Duncan KM, Bowers E, Horn C, Belyavskaya E, et al. Progesterone inhibits mature rat dendritic cells in a receptor-mediated fashion. Int Immunol (2007) 19:287-96. doi:10.1093/intimm/dxl145.
    • (2007) Int Immunol , vol.19 , pp. 287-296
    • Butts, C.L.1    Shukair, S.A.2    Duncan, K.M.3    Bowers, E.4    Horn, C.5    Belyavskaya, E.6
  • 42
    • 59649098857 scopus 로고    scopus 로고
    • Glycodelin A, an immunomodulatory protein in the endometrium, inhibits proliferation and induces apoptosis in monocytic cells
    • doi:10.1016/j.biocel.2008.10.009
    • Alok A, Mukhopadhyay D, Karande AA. Glycodelin A, an immunomodulatory protein in the endometrium, inhibits proliferation and induces apoptosis in monocytic cells. Int J Biochem Cell Biol (2009) 41:1138-47. doi:10.1016/j.biocel.2008.10.009.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 1138-1147
    • Alok, A.1    Mukhopadhyay, D.2    Karande, A.A.3
  • 43
    • 84889567800 scopus 로고    scopus 로고
    • Macrophage phenotype in the mammary gland fluctuates over the course of the estrous cycle and is regulated by ovarian steroid hormones
    • doi:10.1095/biolreprod.113.109561
    • Hodson LJ, Chua ACL, Evdokiou A, Robertson SA, Ingman WV. Macrophage phenotype in the mammary gland fluctuates over the course of the estrous cycle and is regulated by ovarian steroid hormones. Biol Reprod (2013) 89:65. doi:10.1095/biolreprod.113.109561.
    • (2013) Biol Reprod , vol.89 , pp. 65
    • Hodson, L.J.1    Chua, A.C.L.2    Evdokiou, A.3    Robertson, S.A.4    Ingman, W.V.5
  • 45
    • 0036829288 scopus 로고    scopus 로고
    • In vitro modulation of protective antibody responses by estrogen, progesterone and interleukin-6
    • doi:10.1034/j.1600-0897.2002.01141.x
    • Canellada A, Blois S, Gentile T, Margni Idehu RA. In vitro modulation of protective antibody responses by estrogen, progesterone and interleukin-6. Am J Reprod Immunol (2002) 48:334-43. doi:10.1034/j.1600-0897.2002.01141.x.
    • (2002) Am J Reprod Immunol , vol.48 , pp. 334-343
    • Canellada, A.1    Blois, S.2    Gentile, T.3    Margni Idehu, R.A.4
  • 46
    • 77957824512 scopus 로고    scopus 로고
    • New target cells of the immunomodulatory effects of progesterone
    • doi:10.1016/j.rbmo.2010.04.014
    • Kyurkchiev D, Ivanova-Todorova E, Kyurkchiev SD. New target cells of the immunomodulatory effects of progesterone. Reprod Biomed Online (2010) 21:304-11. doi:10.1016/j.rbmo.2010.04.014.
    • (2010) Reprod Biomed Online , vol.21 , pp. 304-311
    • Kyurkchiev, D.1    Ivanova-Todorova, E.2    Kyurkchiev, S.D.3
  • 47
    • 77649178742 scopus 로고    scopus 로고
    • Progesterone treatment reduces disease severity and increases IL-10 in experimental autoimmune encephalomyelitis
    • doi:10.1016/j.jneuroim.2010.01.013
    • Yates MA, Li Y, Chlebeck P, Proctor T, Vandenbark AA, Offner H. Progesterone treatment reduces disease severity and increases IL-10 in experimental autoimmune encephalomyelitis. J Neuroimmunol (2010) 220:136-9. doi:10.1016/j.jneuroim.2010.01.013.
    • (2010) J Neuroimmunol , vol.220 , pp. 136-139
    • Yates, M.A.1    Li, Y.2    Chlebeck, P.3    Proctor, T.4    Vandenbark, A.A.5    Offner, H.6
  • 48
    • 39049142995 scopus 로고    scopus 로고
    • B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
    • doi:10.1056/NEJMoa0706383
    • Hauser SL, Waubant E, Arnold DL, Vollmer T, Antel J, Fox RJ, et al. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med (2008) 358:676-88. doi:10.1056/NEJMoa0706383.
    • (2008) N Engl J Med , vol.358 , pp. 676-688
    • Hauser, S.L.1    Waubant, E.2    Arnold, D.L.3    Vollmer, T.4    Antel, J.5    Fox, R.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.