Endocrine disruption in aquatic vertebrates

Annals of the New York Academy of Sciences

Volumn 1163, Issue , 2009, Pages 187-200

  Kloas, Werner ^a,b   Urbatzka, Ralph ^b   Opitz, Robert ^b   Würtz, Sven ^b   Behrends, Thomas ^b   Hermelink, Björn ^b   Hofmann, Frauke ^b   Jagnytsch, Oana ^b   Kroupova, Hana ^b   Lorenz, Claudia ^b   Neumann, Nadja ^b   Pietsch, Constanze ^b   Trubiroha, Achim ^b   Van Ballegooy, Christoph ^b   Wiedemann, Caterina ^b   Lutz, Ilka ^b  

^a HUMBOLDT UNIVERSITY   (Germany)

^b LEIBNIZ INSTITUTE OF FRESHWATER ECOLOGY AND INLAND FISHERIES   (Germany)

Author keywords

Amphibians; Aquatic vertebrates; Endocrine disruption; Fish; Reproductive biology; Thyroid system

Indexed keywords

ANDROGEN; ENDOCRINE DISRUPTOR; SEX HORMONE;

AMPHIBIA; AQUATIC ENVIRONMENT; AQUATIC SPECIES; BIOAVAILABILITY; CONFERENCE PAPER; ENDANGERED SPECIES; ENDOCRINE SYSTEM; ESTROGEN ACTIVITY; FISH; GENITAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; HYPOTHALAMUS HYPOPHYSIS THYROID SYSTEM; METAMORPHOSIS; NONHUMAN; PARASITE; REPRODUCTION; SEX DIFFERENCE; STEROIDOGENESIS; THYROID GLAND;

AMPHIBIA; VERTEBRATA;

EID: 65449135197     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.04453.x     Document Type: Conference Paper

References (78)

1. Norris, D.O. 2007. Vertebrate Endocrinology. Academic Press. San Diego.
2. Colborn, C. C. Clement. 1992. Chemically Induced Alterations in Sexual and Functional Development. The Wildlife/Human Connection. Princeton Scientific Publishing. Princeton.
3. European Commission. 1996. European Workshop on the Impact of Endocrine Disruptors on Human Health and Wildlife. Weybridge, 2-4 Dec. Report Eur 17549, Environment and Climate Research Program, DG XII.
4. Kloas, W. 2002. Amphibians as a model for the study of endocrine disruptors. Int. Rev. Cytol. 216 : 1 57. (Pubitemid 34552685)
5. Kime, D. 1998. Endocrine Disruption in Fish. Kluwer Academic Publishers. Boston, Dordrecht, London.
6. Urbatzka, R. et al. 2007. Androgenic and antiandrogenic activities in water and sediment samples from the river Lambro, Italy, detected by yeast androgen screen and chemical analyses. Chemosphere 67 : 1080 1087. (Pubitemid 46185543)
7. Sumpter, J.P. A.C. Johnson. 2005. Lessons from endocrine disruption and their application to other issues concerning trace organics in the aquatic environment. Environ. Sci. Technol. 39 : 4321 4332. (Pubitemid 40853113)
8. Sumpter, J.P. 2008. The ecotoxicology of hormonally active micropollutants. Water Sci. Technol. 57 : 125 130.
9. CEC. 2003. Proposal for a Regulation of the European Parliament and of the Council Concerning the Registration, authorisation and Registration of Chemicals (REACH), establishing a European Chemicals Agency and amending directive 1999/45EC and Regulation (EC) (on persistent organic pollutants) (COM(2003) 644, 29 October, Brussels, 158 pp http://ecb.jrc.it/REACH).
10. Matthiessen, P. I. Johnson. 2007. Implications of research on endocrine disruption for the environmental risk assessment, regulation and monitoring of chemicals in the European Union. Env. Pol. 146 : 9 18. (Pubitemid 46161934)
11. Purdom, P. 1994. Estrogenic effects of effluents from sewage treatment works. Chem. Ecol. 8 : 275 285.
12. Bjerregaard, L.B. et al. 2006. Intersex in wild roach (Rutilus rutilus) from Danish sewage effluent-receiving streams. Ecotoxicol. Environ. Saf. 64 : 321 328. (Pubitemid 43841822)
13. Mills, L.J. C. Chichester. 2005. Review of evidence: are endocrine-disrupting chemicals in the aquatic environment impacting fish populations? Sci. Total Envir. 343 : 1 45. (Pubitemid 40615884)
14. Rempel, M.A. D. Schlenk. 2008. Effects of environmental estrogens and antiandrogens on endocrine function, gene regulation, and health in fish. Int. Rev. Cell Mol. Biol. 267 : 207 252.
15. Jobling, S. C.R. Tyler. 2006. Introduction: the ecological relevance of chemically induced endocrine disruption in wildlife. Environ. Health Perspect. 114 (Suppl 1 7 8. (Pubitemid 41715158)
16. Hutchinson, T.H. et al. 2006. Screening and testing for endocrine disruption in fish-biomarkers as "signposts," not "traffic lights," in risk assessment. Environ. Health Perspect. 114 (Suppl 1 106 114.
17. Carey, C. C.J. Bryant. 1995. Possible interrelations among environmental toxicants, amphibian development, and decline of amphibian populations. Environ. Health Perspect. 103 (Suppl 4 13 17.
18. Kloas, W. et al. 1999. Amphibians as a model to study endocrine disruptors: II. Estrogenic activity of environmental chemicals in vitro and in vivo. Sci. Total Envir. 225 : 59 68. (Pubitemid 29148046)
19. Kloas, W. I. Lutz. 2006. Amphibians as model to study endocrine disrupters. J. Chromatogr. A 1130 : 16 27. (Pubitemid 44397082)
20. Kloas, W. I. Lutz. 2009. The hypothalamic-pituitary-gonadal axis in anuran amphibians. In Endocrine Toxicology. C. Eldridge & J. Stevens, Eds. In press.
21. Van Der Kraak, G. 2009. The hypothalamic-pituitary-gonadal axis in teleosts. In Endocrine Toxicology. C. Eldridge & J. Stevens, Eds. In press.
22. Tsai, P.S. et al. 2003. Effects of steroid hormones on spermatogenesis and GnRH release in male Leopard frogs, Rana pipiens. Gen. Comp. Endocrinol. 134 : 330 338. (Pubitemid 37443489)
23. Tsai, P.S. et al. 2005. Alteration of the hypothalamic-pituitary-gonadal axis in estrogen- and androgen-treated adult male leopard frog, Rana pipiens. Reprod. Biol. Endocrinol. 3 : 2.
24. Zhang, L. et al. 2007. Characterization and steroidal regulation of gonadotropin beta subunits in the male leopard frog, Rana pipiens. Gen. Comp. Endocrinol. 150 : 66 74.
25. Mosconi, G. et al. 2002. Environmental estrogens and reproductive biology in amphibians. Gen. Comp. Endocrinol. 126 : 125 129. (Pubitemid 34521616)
26. Urbatzka, R. et al. 2006. Luteinizing hormone, follicle stimulating hormone, and gonadotropin releasing hormone mRNA expression of Xenopus laevis in response to endocrine disrupting compounds affecting reproductive biology. Gen. Comp. Endocrinol. 146 : 119 125. (Pubitemid 43351164)
27. Urbatzka, R. et al. 2007. Endocrine disrupters with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: I. Effects on sex steroid levels and biomarker expression. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 144 : 310 318. (Pubitemid 46177768)
28. Cevasco, A. et al. 2008. Endocrine disrupting chemicals (EDC) with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: II. Effects on gonad histomorphology. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 147 : 241 251. (Pubitemid 350302046)
29. Behrends, T. 2008. The antiandrogen flutamide supresses mating call behaviour in male Xenopus laevis. Diploma thesis, Humboldt University, Germany.
30. Witschi, E. J. Allison. 1950. Responses of Xenopus and Alytes to the administration of some steroid hormones. Anat.Rec. 108 : 589 590.
31. Rastogi, R.K. G. Chieffi. 1975. The effects of antiandrogens and antiestrogens in nonmammalian vertebrates. Gen. Comp. Endocrinol. 26 : 79 91.
32. Hayes, T.B. 1998. Sex determination and primary sex differentiation in amphibians: genetic and developmental mechanisms. J. Exp. Zool. 281 : 373 399. (Pubitemid 28324725)
33. Boegi, C. et al. 2002. Functional genomics and sexual differentiation in amphibians. Comp. Biochem. Physiol. PT B. 133 : 559 570. (Pubitemid 35441081)
34. Hu, F. et al. 2007. Effects of larval exposure to estradiol on spermatogenesis and in vitro gonadal steroid secretion in African clawed frogs, Xenopus laevis. Gen. Comp. Endocrinol. 155 : 190 200.
35. Oka, T. et al. 2008. Effect of atrazine on metamorphosis and sexual differentiation in Xenopus laevis. Aquat. Toxicol. 87 : 215 226.
36. Pettersson, I. C. Berg. 2007. Environmentally relevant concentrations of ethynylestradiol cause female-biased sex ratios in Xenopus tropicalis and Rana temporaria. Env. Toxi. Chem. 26 : 1005 1009. (Pubitemid 46799759)
37. Maack, G. et al. 2004. Life-stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 139 : 47 55. (Pubitemid 39535787)
38. Maradonna, F. et al. 2007. Vitellogenin, zona radiata protein, cathepsin D and heat shock protein 70 as biomarkers of response to xenobiotics. Biomarkers 12 : 240 255. (Pubitemid 46681028)
39. Madsen, S.S. et al. 2004. 17-Beta estradiol and 4-nonylphenol delay smolt development and downstream migration in Atlantic salmon, Salmo salar. Aquat. Toxicol. 68 : 109 120. (Pubitemid 38622485)
40. Larsen, M.G. et al. 2008. Male zebrafish (Danio rerio) courtship behaviour resists the feminising effects of 17alpha-ethinyloestradiol- morphological sexual characteristics do not. Aquat. Toxicol. 87 : 234 244.
41. Leanos-Castaneda, O. et al. 2004. An aromatase inhibitor and tamoxifen decrease plasma levels of o,p'-DDT and its metabolites in Nile tilapia (Oreochromis niloticus). Mar. Environ. Res. 58 : 337 342. (Pubitemid 38738899)
42. Cheshenko, K. et al. 2008. Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish. Gen. Comp. Endocrinol. 155 : 31 62. (Pubitemid 350122476)
43. Martinovic, D. et al. 2008. Reproductive toxicity of vinclozolin in the fathead minnow: confirming an anti-androgenic mode of action. Environ. Toxicol. Chem. 27 : 478 488.
44. Leon, A. et al. 2007. Androgen disruption of early development in Qurt strain medaka (Oryzias latipes). Aquat. Toxicol. 82 : 195 203. (Pubitemid 46517667)
45. Katsiadaki, I. et al. 2002. The potential of the three-spined stickleback (Gasterosteus aculeatus L.) as a combined biomarker for oestrogens and androgens in European waters. Mar. Environ. Res. 54 : 725 728. (Pubitemid 35286502)
46. Hahlbeck, E. et al. 2004. The juvenile three-spined stickleback (Gasterosteus aculeatus L.) as a model organism for endocrine disruption. I. Sexual differentiation. Aquat. Toxicol. 70 : 287 310. (Pubitemid 39575023)
47. Hahlbeck, E. et al. 2004. The juvenile three-spined stickleback (Gasterosteus aculeatus L.) as a model organism for endocrine disruption. II. Kidney hypertrophy, vitellogenin and spiggin induction. Aquat. Toxicol. 70 : 311 326. (Pubitemid 39575024)
48. Katsiadaki, I. et al. 2006. Use of the three-spined stickleback (Gasterosteus aculeatus) as a sensitive in vivo test for detection of environmental antiandrogens. Environ. Health Perspect. 114 (Suppl 1 115 121.
49. Björkblom, C. et al. 2007. Estrogen- and androgen-sensitive bioassays based on primary cell and tissue slice cultures from three-spined stickleback (Gasterosteus aculeatus). Comp. Biochem. Physiol C. Toxicol. Pharmacol. 146 : 431 442. (Pubitemid 47127018)
50. Maunder, R.J. et al. 2007. Impaired reproduction in three-spined sticklebacks exposed to ethinyl estradiol as juveniles. Biol. Reprod. 77 : 999 1006. (Pubitemid 350197977)
51. Mccormick, S.D. et al. 2005. Endocrine disruption of parr-smolt transformation and seawater tolerance of Atlantic salmon by 4-nonylphenol and 17beta-estradiol. Gen. Comp. Endocrinol. 142 : 280 288. (Pubitemid 40780089)
52. Filby, A.L. et al. 2006. Multiple molecular effect pathways of an environmental oestrogen in fish. J. Mol. Endocrinol. 37 : 121 134. (Pubitemid 44288611)
53. Filby, A.L. et al. 2007. Gene expression profiles revealing the mechanisms of anti-androgen- and estrogen-induced feminizaiton in fish. Aquat. Toxicol. 81 : 219 231. (Pubitemid 46216473)
54. Brucker-Davis, F. 1998. Effects of environmental synthetic chemicals on thyroid function. Thyroid 8 : 827 856. (Pubitemid 28535695)
55. Shi, Y.B. 2000. Amphibian Metamorphosis. Wiley-Liss. New York.
56. Eales, J.G. et al. 1993. Measurement and regulation of thyroidal status in teleost fish. Rev. Fish Biol. Fisher. 23 : 299 347.
57. Yaoita, Y. et al. 1990. Xenopus laevis alpha and beta thyroid hormone receptors. Proc. Natl. Acad. Sci. USA 87 : 7090 7094. (Pubitemid 20325212)
58. Kikuyama, S. et al. 1993. Aspects of amphibian metamorphosis: hormonal control. Int. Rev. Cytol. 145 : 105 148. (Pubitemid 23223465)
59. Opitz, R. et al. 2005. Description and initial evaluation of a Xenopus metamorphosis assay for detection of thyroid system-disrupting activities of environmental compounds. Environ. Toxicol. Chem. 24 : 653 664. (Pubitemid 40270291)
60. Tietge, J.E. et al. 2005. Metamorphic inhibition of Xenopus laevis by sodium perchlorate: effects on development and thyroid histology. Environ. Toxicol. Chem. 24 : 926 933. (Pubitemid 40404563)
61. Opitz, R. et al. 2006. The analysis of thyroid hormone receptor ßA mRNA expression in Xenopus laevis tadpoles as a means to detect agonism and antagonism of thyroid hormone action. Tox. Appl. Pharmaco. 212 : 1 13.
62. Opitz, R. et al. 2006. Evaluation of histological and molecular endpoints for enhanced detection of thyroid system disruption in Xenopus laevis tadpoles. Toxicol. Sci. 90 : 337 348. (Pubitemid 41758445)
63. Crane, H.M. et al. 2005. Effects of ammonium perchlorate on thyroid function in developing fathead minnows, Pimephales promelas. Environ. Health Perspect. 113 : 396 401. (Pubitemid 40601815)
64. Bradford, C.M. et al. 2005. Perchlorate affects thyroid function in eastern mosquitofish (Gambusia holbrooki) at environmentally relevant concentrations. Environ. Sci. Technol. 39 : 5190 5195. (Pubitemid 41003735)
65. Van Der Veen, L.T.M. et al. 2006. Effects of the antithyroid agent propylthiouracil in a partial life cycle assay with zebrafish. Environ. Sci. Technol. 40 : 74 81. (Pubitemid 43069888)
66. Bernhardt, R.R. et al. 2006. Perchlorate induces hermaphroditism in threespine sticklebacks. Environ. Toxicol. Chem. 25 : 2087 2096.
67. Bernhardt, R.R. et al. 2008. Chronic perchlorate exposure impairs stickleback reproductive behaviour and swimming performance. Behaviour 145 : 527 559.
68. Blanton, M.L. J.L. Specker. 2007. The hypothalamic-pituitary-thyroid (HPT) axis in fish and its role in fish development and reproduction. Crit. Rev. Toxicol. 37 : 97 115. (Pubitemid 46269180)
69. Theodorakis, C.W. et al. 2006. Thyroid endocrine disruption in stonerollers and cricket frogs from perchlorate-contaminated streams in east-central Texas. Ecotoxicology 15 : 31 50. (Pubitemid 43373653)
70. Hermelink, B. et al. 2008. Endocrine activities of leaf extracts and their influence on larval development of Xenopus laevis concerning sexual differentiation. Presented at the Meeting of the Conference of European Comparative Endocrinologists. Genova, Italy, September 2.
71. Sures, B. 2006. How parasitism and pollution affect the physiological homeostasis of aquatic hosts. J. Helminthology 80 : 151 157. (Pubitemid 44065907)
72. Schabuss, M. et al. 2005. Ligula intestinalis infection as a potential source of bias in the bioindication of endocrine disruption in the European chub Leuciscus cephalus. J. Helminthol. 79 : 91 94. (Pubitemid 40525026)
73. Trubiroha, A. et al. 2008. Endocrine disruptive effects in fish induced by parasites. Presented at the Meeting of the Conference of European Comparative Endocrinologists. Genova, Italy, September 2.
74. Lorenz, C. et al. 2008. Effects of corticosterone on thyroid hormone dependent metamorphosis of the amphibian Xenopus laevis. Presented at the Meeting of the Conference of European Comparative Endocrinologists. Genova, Italy, September 2.
75. Kloas, W. 2008. Endocrine disruption in aquatic vertebrates. Presented at the Meeting of the Conference of European Comparative Endocrinologists. Genova, Italy, September 2.
76. Daughton, C.G. T.A. Ternes. 1999. Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ. Health Perspect. 107 : 907 938. (Pubitemid 30068192)
77. Iguchi, T. et al. 2006. Application of ecotoxicogenomics for studying endocrine disruption in vertebrates and invertebrates. Environ. Health Perspect. 114 : 101 105.
78. Lutz, I. et al. 2008. Development, standardization and refinement of procedures for evaluating effects of endocrine active compounds on development and sexual differentiation of Xenopus laevis. Anal. Bioanal. Chem. 390 : 2031 2048.