Contraceptive progestins. Various 11-substituents combined with four 17-substituents: 17α-ethynyl, five- and six-membered spiromethylene ethers or six-membered spiromethylene lactones

Journal of Steroid Biochemistry and Molecular Biology

Volumn 74, Issue 3, 2000, Pages 109-123

  Schoonen, W G E J ^a   Deckers, G ^a   De Gooijer, M E ^a   De Ries, R ^a   Mathijssen Mommers, G ^a   Hamersma, H ^a   Kloosterboer, H J ^a  

^a NV ORGANON   (Netherlands)

Author keywords

3 Keto desogestrel; Androgenic activity; Competition studies; Etonogestrel; Glucocorticoid activity; New progestagens; Progestational activity; Steroid receptors

Indexed keywords

ANDROGEN RECEPTOR; DESOGESTREL; ESTROGEN RECEPTOR; ETONOGESTREL; GESTODENE; GLUCOCORTICOID RECEPTOR; LACTONE DERIVATIVE; LEVONORGESTREL; NORETHISTERONE; PROGESTERONE DERIVATIVE; PROGESTERONE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTRACEPTION; DRUG ACTIVATION; DRUG POTENCY; DRUG STRUCTURE; ESTROGEN ACTIVITY; FEMALE; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; NONHUMAN; OVULATION INHIBITION; RAT;

ADMINISTRATION, ORAL; ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHERS; FEMALE; HUMANS; HYDROCARBONS; INJECTIONS, SUBCUTANEOUS; LACTONES; METHANE; ORCHIECTOMY; OVULATION; PROGESTINS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; RECEPTORS, GLUCOCORTICOID; RECEPTORS, PROGESTERONE; SPIRO COMPOUNDS; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED;

EID: 0033735999     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(00)00094-7     Document Type: Article

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