Tissue-specific uptake and bioconcentration of the oral contraceptive norethindrone in two freshwater fishes

Archives of Environmental Contamination and Toxicology

Volumn 62, Issue 2, 2012, Pages 306-313

  Nallani, Gopinath C ^a,c   Paulos, Peter M ^a   Venables, Barney J ^a   Edziyie, Regina E ^a   Constantine, Lisa A ^b   Huggett, Duane B ^a  

^a UNIVERSITY OF NORTH TEXAS   (United States)

^b PFIZER INC   (United States)

^c ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NORETHISTERONE;

BIOACCUMULATION; BIOLOGICAL UPTAKE; CONCENTRATION (COMPOSITION); CONTRACEPTIVE USE; CYPRINID; DEPURATION; DRUG; ESTROGENIC COMPOUND; FINFISH; FRESHWATER; POLLUTION EXPOSURE; REPRODUCTION;

ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BRAIN; CHANNEL CATFISH; GILL; KIDNEY; LIVER; MASS FRAGMENTOGRAPHY; MUSCLE; NONHUMAN; PIMEPHALES PROMELAS; PRIORITY JOURNAL;

ANIMALS; CONTRACEPTIVES, ORAL; CYPRINIDAE; ENVIRONMENTAL MONITORING; FRESH WATER; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; ICTALURIDAE; KIDNEY; LINEAR MODELS; LIVER; MALE; MUSCLES; NONLINEAR DYNAMICS; NORETHINDRONE; REPRODUCTION; WATER POLLUTANTS, CHEMICAL; WATER QUALITY;

ICTALURUS PUNCTATUS; PIMEPHALES PROMELAS; PISCES;

EID: 84856955505     PISSN: 00904341     EISSN: 14320703     Source Type: Journal    
DOI: 10.1007/s00244-011-9691-x     Document Type: Article

References (39)

1. AM Al-Ansari A Saleem LE Kimpe JP Sherry ME McMaster VL Trudeau, et al. 2010 Bioaccumulation of the pharmaceutical 17 [alpha]-ethinylestradiol in shorthead redhorse suckers (Moxostoma macrolepidotum) from the St. Clair River, Canada Environ Pollut 158 2566 2571 10.1016/j.envpol.2010.05.020 1:CAS:528:DC%2BC3cXos1yktrY%3D
2. MJL Alda A Gil E Paz D Barceló 2002 Occurrence and analysis of estrogens and progestogens in river sediments by liquid chromatography- electrospray-mass spectrometry Analyst 127 1299 1304 10.1039/b207658f (Pubitemid 35216894)
3. H Andersen M Hansen J Kjølholt F Stuer-Lauridsen T Ternes B Halling Sørensen 2005 Assessment of the importance of sorption for steroid estrogens removal during activated sludge treatment Chemosphere 61 139 146 10.1016/j.chemosphere.2005.02.088 1:CAS:528:DC%2BD2MXhtVWns7rM (Pubitemid 41266920)
4. JA Arnot FACP Gobas 2006 A review of bioconcentration factor (BCF) and bioaccumulation factor (BAF) assessments for organic chemicals in aquatic organisms Environ Rev 14 257 297 10.1139/a06-005 1:CAS:528:DC%2BD2sXitFGktbk%3D (Pubitemid 46276957)
5. JP Besse J Garric 2009 Progestagens for human use, exposure and hazard assessment for the aquatic environment Environ Pollut 157 3485 3494 10.1016/j.envpol.2009.06.012 1:CAS:528:DC%2BD1MXhtlyru7%2FP
6. C Carlsson AK Johansson G Alvan K Bergman T Kühler 2006 Are pharmaceuticals potent environmental pollutants? Part I: environmental risk assessments of selected active pharmaceutical ingredients Sci Total Environ 364 67 87 10.1016/j.scitotenv.2005.06.035 1:CAS:528:DC%2BD28XltFChtbk%3D (Pubitemid 44218712)
7. C Desbrow EJ Routledge GC Brighty JP Sumpter M Waldock 1998 Identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening Environ Sci Technol 32 1549 1558 10.1021/es9707973 1:CAS:528:DyaK1cXislSht7s%3D (Pubitemid 28265342)
8. B Dussault VK Balakrishnan U Borgmann KR Solomon PK Sibley 2009 Bioaccumulation of the synthetic hormone 17 [alpha]-ethinylestradiol in the benthic invertebrates Chironomus tentans and Hyalella azteca Ecotoxicol Environ Saf 72 1635 1641 10.1016/j.ecoenv.2009.04.019 1:CAS:528:DC%2BD1MXhtVSmsbnO
9. EA EM (2006) Note for guidance on environmental risk assessment of medicinal products for human use. Committee for Proprietary Medicinal Products, London
10. European Commission (2003) Technical guidance document on risk assessment in support of Commission Directive 93/67/EEC on risk assessment for new notified substances, Commission Regulation (EC) No 1488/94 on risk assessment for existing substances, and Directive 98/8/EC of the European Parliament and of the Council concerning the placing of biocidal products on the market
11. RL Gomes HE Deacon KM Lai JW Birkett MD Scrimshaw JN Lester 2004 An assessment of the bioaccumulation of estrone in Daphnia magna Environ Toxicol Chem 23 105 108 10.1897/02-613 1:CAS:528:DC%2BD2cXjvVKmtQ%3D%3D (Pubitemid 38049658)
12. CF Gomez L Constantine DB Huggett 2010 The influence of gill and liver metabolism on the predicted bioconcentration of three pharmaceuticals in fish Chemosphere 10 1189 1195 10.1016/j.chemosphere.2010.09.043
13. L Gunnarsson A Jauhiainen E Kristiansson O Nerman DGJ Larsson 2008 Evolutionary conservation of human drug targets in organisms used for environmental risk assessments Environ Sci Technol 42 5807 5813 10.1021/es8005173 1:CAS:528:DC%2BD1cXns1yqtrY%3D
14. DB Huggett JC Cook JF Ericson RT Williams 2003 A theoretical model for utilizing mammalian pharmacology and safety data to prioritize potential impacts of human pharmaceuticals to fish Hum Ecol Risk Assess 9 1789 1799 10.1080/714044797 1:CAS:528:DC%2BD2cXmt1Wqtg%3D%3D (Pubitemid 38571547)
15. Huggett DB, Ericson JC, Cook JF, Williams RT (2004) Plasma concentrations of human pharmaceuticals as predictors of pharmacological responses in fish. In: Kummerer K (ed) Pharmaceuticals in the environment: sources, fate, effects and risks, 2nd edn. Springer, Berlin, p 373
16. S Jobling M Nolan CR Tyler G Brighty JP Sumpter 1998 Widespread sexual disruption in wild fish Environ Sci Technol 32 2498 2506 10.1021/es9710870 1:CAS:528:DyaK1cXkvVKjsLw%3D (Pubitemid 28420276)
17. JM Kallio M Lahti A Oikari L Kronberg 2010 Metabolites of the aquatic pollutant diclofenac in fish bile Environ Sci Technol 44 357 393 10.1021/es903402c
18. KA Kidd PJ Blanchfield KH Mills VP Palace RE Evans JM Lazorchak, et al. 2007 Collapse of a fish population after exposure to a synthetic estrogen Proc Natl Acad Sci 104 8897 10.1073/pnas.0609568104 1:CAS:528:DC%2BD2sXmt1WgtLY%3D (Pubitemid 47175408)
19. M Kuster José López M de Alda D Barceló 2004 Analysis and distribution of estrogens and progestogens in sewage sludge, soils and sediments Trends Anal Chem 23 790 798 10.1016/j.trac.2004.08.007 1:CAS:528:DC%2BD2cXhtVCmtbbF (Pubitemid 39572672)
20. P Labadie H Budzinski 2005 Development of an analytical procedure for determination of selected estrogens and progestagens in water samples Anal Bioanal Chem 381 1199 1205 10.1007/s00216-005-3055-1 1:CAS:528: DC%2BD2MXisFygtLo%3D (Pubitemid 40512260)
21. KM Lai MD Scrimshaw JN Lester 2002 Biotransformation and bioconcentration of steroid estrogens by Chlorella vulgaris Appl Environ Microbiol 68 859 864 10.1128/AEM.68.2.859-864.2002 1:CAS:528:DC%2BD38XhtV2nsb4%3D (Pubitemid 34113078)
22. R Länge TH Hutchinson CP Croudace F Siegmund H Schweinfurth P Hampe, et al. 2001 Effects of the synthetic estrogen 17-ethinylestradiol on the life-cycle of the fathead minnow (Pimephales promelas) Environ Toxicol Chem 20 1216 1227 (Pubitemid 32861474)
23. DGJ Larsson M Adolfsson-Erici J Parkkonen M Pettersson AH Berg PE Olsson, et al. 1999 Ethinyloestradiol - an undesired fish contraceptive? Aquat Toxicol 45 91 97 10.1016/S0166-445X(98)00112-X 1:CAS:528:DyaK1MXhsVWgt7s%3D (Pubitemid 29112824)
24. S Markman IA Guschina S Barnsley KL Buchanan D Pascoe CT Müller 2007 Endocrine disrupting chemicals accumulate in earthworms exposed to sewage effluent Chemosphere 70 119 125 10.1016/j.chemosphere.2007.06.045 1:CAS:528:DC%2BD2sXht1KrtbnL (Pubitemid 350016236)
25. RJ Maunder P Matthiessen JP Sumpter TG Pottinger 2007 Rapid bioconcentration of steroids in the plasma of three-spined stickleback Gasterosteus aculeatus exposed to waterborne testosterone and 17-oestradiol J Fish Biol 70 678 690 10.1111/j.1095-8649.2006.01303.x 1:CAS:528: DC%2BD2sXksVOlu7g%3D
26. Newman MC (1995) Quantitative methods in aquatic ecotoxicology. CRC, Boca Raton
27. Organization for Economic Co-operation and Development (1996) OECD guidelines for the testing of chemicals. Section 3. Degradation and accumulation test TG No. 305. Bioconcentration: flow-through fish test. OECD
28. G Paterson CD Metcalfe 2008 Uptake and depuration of the anti-depressant fluoxetine by the Japanese medaka (Oryzias latipes) Chemosphere 74 125 130 10.1016/j.chemosphere.2008.08.022 1:CAS:528:DC%2BD1cXhtlylurnP
29. P Paulos TJ Runnalls G Nallani T La Point AP Scott JP Sumpter, et al. 2010 Reproductive responses in fathead minnow and Japanese medaka following exposure to a synthetic progestin, norethindrone Aquat Toxicol 99 256 262 10.1016/j.aquatox.2010.05.001 1:CAS:528:DC%2BC3cXosV2jsb4%3D
30. M Pettersson M Adolfsson-Erici J Parkkonen L Förlin L Asplund 2006 Fish bile used to detect estrogenic substances in treated sewage water Sci Total Environ 366 174 186 10.1016/j.scitotenv.2005.07.005 1:CAS:528: DC%2BD28XmvValsro%3D
31. CE Purdom PA Hardiman VVJ Bye NC Eno CR Tyler JP Sumpter 1994 Estrogenic effects of effluents from sewage treatment works Chem Ecol 8 275 285 10.1080/02757549408038554 1:CAS:528:DyaK2cXms1altLo%3D
32. J Schwaiger H Ferling U Mallow H Wintermayr RD Negele 2004 Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part I: histopathological alterations and bioaccumulation in rainbow trout Aquat Toxicol 68 141 150 10.1016/j.aquatox.2004.03.014 1:CAS:528:DC%2BD2cXktVCnt7w%3D (Pubitemid 38622488)
33. A Shareef MJ Angove JD Wells 2006 Optimization of silylation using N-methyl-N-(trimethylsilyl)-trifluoroacetamide, N, O-bis-(trimethylsilyl)- trifluoroacetamide and N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide for the determination of the estrogens estrone and 17 [alpha]-ethinylestradiol by gas chromatography-mass spectrometry J Chromatogr A 1108 121 128 10.1016/j.chroma.2005.12.098 1:CAS:528:DC%2BD28XhtlaksLs%3D (Pubitemid 43202638)
34. JP Sumpter S Jobling 1995 Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment Environ Health Perspect 103 173 178 1:CAS:528:DyaK28XlvFehtw%3D%3D
35. TA Ternes M Stumpf J Mueller K Haberer RD Wilken M Servos 1999 Behavior and occurrence of estrogens in municipal sewage treatment plants. I. Investigations in Germany, Canada and Brazil Sci Total Environ 225 81 90 10.1016/S0048-9697(98)00334-9 1:CAS:528:DyaK1MXhsVKmtg%3D%3D (Pubitemid 29148048)
36. TA Ternes H Andersen D Gilberg M Bonerz 2002 Determination of estrogens in sludge and sediments by liquid extraction and GC/MS/MS Anal Chem 74 3498 3504 10.1021/ac015717z 1:CAS:528:DC%2BD38XjvVyju7c%3D (Pubitemid 34764959)
37. CR Tyler B Van der Eerden S Jobling G Panter JP Sumpter 1996 Measurement of vitellogenin, a biomarker for exposure to oestrogenic chemicals, in a wide variety of cyprinid fish J Comp Physiol B 166 418 426 10.1007/BF02337886 1:CAS:528:DyaK2sXjt12iur0%3D (Pubitemid 27012477)
38. CR Tyler S Jobling JP Sumpter 1998 Endocrine disruption in wildlife: a critical review of the evidence Crit Rev Toxicol 28 319 361 10.1080/ 10408449891344236 1:STN:280:DyaK1cznslaqsw%3D%3D (Pubitemid 28389719)
39. Woodburn K, Springer T (2004) Modifications of standard regulatory bioconcentration protocols to decrease exposure time, cost, and use of animals [abstract]. In: Proceedings of society of environmental toxicology and chemistry annual meeting, 14-17 Nov 2005, Pensacola, FL