The spectrum of fungi that infects humans

Cold Spring Harbor Perspectives in Medicine

Volumn 5, Issue 1, 2015, Pages

  Köhler, Julia R ^a   Casadevall, Arturo ^b   Perfect, John ^c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AJELLOMYCES CAPSULATUS; AJELLOMYCES DERMATITIDIS; ARTICLE; ASCOMYCETES; ASPERGILLUS FUMIGATUS; BASIDIOBOLOMYCOSIS; BASIDIOBOLUS; BASIDIOBOLUS RANARUM; BASIDIOMYCETES; CANDIDA ALBICANS; CELLULAR IMMUNITY; CONIDIOBOLOMYCOSIS; CONIDIOBOLUS; CONIDIOBOLUS INCONGRUUS; CRYPTOCOCCOSIS; CRYPTOCOCCUS; CRYPTOCOCCUS GATTII; CRYPTOCOCCUS NEOFORMANS; ENTOMOPHTHOROMYCOTA; FUNGAL CELL; FUNGAL VIRULENCE; FUNGUS; FUSARIUM; HISTOPLASMA; HISTOPLASMOSIS; HOST PATHOGEN INTERACTION; HUMAN; IMMUNE SYSTEM; IMMUNOCOMPETENCE; IMMUNOCOMPROMISED PATIENT; INVASIVE ASPERGILLOSIS; INVASIVE CANDIDIASIS; MALASSEZIA FURFUR; MUCORALES; MYCOLOGY; MYCOSIS; NONHUMAN; ONYGENALES; SCEDOSPORIUM BOYDII; TRICHOSPORON ASAHII; EVOLUTION; IMMUNOLOGY; INNATE IMMUNITY; MICROBIOLOGY; OPPORTUNISTIC INFECTION; PATHOGENICITY; PHYSIOLOGY; VIRULENCE;

FUNGI;

BIOLOGICAL EVOLUTION; FUNGI; HUMANS; IMMUNITY, INNATE; IMMUNOCOMPROMISED HOST; MYCOSES; OPPORTUNISTIC INFECTIONS; VIRULENCE;

EID: 84923817688     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a019273     Document Type: Article

References (235)

1. Abad A, Fernandez-Molina JV, Bikandi J, Ramirez A, Margareto J, Sendino J, Hernando FL, Ponton J, Garaizar J, Rementeria A. 2010. What makes Aspergillus fumigatus a successful pathogen? Genes and molecules involved in invasive aspergillosis. Rev Iberoam Micol 27: 155-182.
2. Aimanianda V, Bayry J, Bozza S, Kniemeyer O, Perruccio K, Elluru SR, Clavaud C, Paris S, Brakhage AA, Kaveri SV, et al. 2009. Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature 460: 1117-1121.
3. Albrecht A, Felk A, Pichova I, Naglik JR, Schaller M, de Groot P, Maccallum D, Odds FC, Schafer W, Klis F, et al. 2006. Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions. J Biol Chem 281: 688-694.
4. Alby K, Schaefer D, Bennett RJ. 2009. Homothallic and heterothallic mating in the opportunistic pathogen Candida albicans. Nature 460: 890-893.
5. Ameen M. 2010. Epidemiology of superficial fungal infections. Clin Dermatol 28: 197-201.
6. Araujo Gde S, Fonseca FL, Pontes B, Torres A, Cordero RJ, Zancope-Oliveira RM, Casadevall A, Viana NB, Nimrichter L, Rodrigues ML, et al. 2012. Capsules from pathogenic and non-pathogenic Cryptococcus spp. manifest significant differences in structure and ability to protect against phagocytic cells. PLoS ONE 7: e29561.
7. Argimon S, Fanning S, Blankenship JR, Mitchell AP. 2011. Interaction between the Candida albicans high-osmolarity glycerol (HOG) pathway and the response to human b-defensins 2 and 3. Eukaryot Cell 10: 272-275.
8. Aulakh HK, Aulakh KS, Troy GC. 2012. Feline histoplasmosis: A retrospective study of 22 cases (1986-2009). J Am Anim Hosp Assoc 48: 182-187.
9. Bagagli E, Bosco SM, Theodoro RC, Franco M. 2006. Phylogenetic and evolutionary aspects of Paracoccidioides brasiliensis reveal a long coexistence with animal hosts that explain several biological features of the pathogen. Infect Genet Evol 6: 344-351.
10. Bagagli E, Theodoro RC, Bosco SM, McEwen JG. 2008. Paracoccidioides brasiliensis: Phylogenetic and ecological aspects. Mycopathologia 165: 197-207.
11. Bastidas RJ, Heitman J. 2009. Trimorphic stepping stones pave the way to fungal virulence. Proc Natl Acad Sci 106: 351-352.
12. Bauder B, Kubber-Heiss A, Steineck T, Kuttin ES, Kaufman L. 2000. Granulomatous skin lesions due to histoplasmosis in a badger (Meles meles) in Austria. Med Mycol 38: 249-253.
13. Bergman A, Casadevall A. 2010. Mammalian endothermy optimally restricts fungi and metabolic costs. MBio 1: e00212-10.
14. Beyhan S, Gutierrez M, Voorhies M, Sil A. 2013. A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. PLoS Biol 11: e1001614.
15. Bittencourt AL. 1988. Entomophthoromycosis. Review. Med Cutan Ibero Lat Am 16: 93-100.
16. Bittencourt AL, Marback R, Nossa LM. 2006. Mucocutaneous entomophthoramycosis acquired by conjunctival inoculation of the fungus. Am J Trop Med Hyg 75: 936-938.
17. Blake JS, Dahl MV, Herron MJ, Nelson RD. 1991. An immunoinhibitory cell wall glycoprotein (Mannan) from Trichophyton rubrum. J Invest Dermatol 96: 657-661.
18. Boelaert JR, de Locht M, Van Cutsem J, Kerrels V, Cantinieaux B, Verdonck A, Van Landuyt HW, Schneider YJ. 1993. Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animal studies. J Clin Invest 91: 1979-1986.
19. Bohse ML, Woods JP. 2007. Expression and interstrain variability of the YPS3 gene of Histoplasma capsulatum. Eukaryot Cell 6: 609-615.
20. Bougnoux ME, Pujol C, Diogo D, Bouchier C, Soll DR, d’Enfert C. 2008. Mating is rare within as well as between clades of the human pathogen Candida albicans. Fungal Genet Biol 45: 221-231.
21. Bowen AD, Davidson FA, Keatch R, Gadd GM. 2007. Induction of contour sensing in Aspergillus niger by stress and its relevance to fungal growth mechanics and hyphal tip structure. Fungal Genet Biol 44: 484-491.
22. Bradsher RW, Chapman SW, Pappas PG. 2003. Blastomycosis. Infect Dis Clin North Am 17: 21-40.
23. Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, Weinrauch Y, Zychlinsky A. 2004. Neutrophil extracellular traps kill bacteria. Science 303: 1532-1535.
24. Brömel C, Sykes JE. 2005. Histoplasmosis in dogs and cats. Clin Tech Small Anim Pract 20: 227-232.
25. Browne SG. 1954. Moniliasis following antibiotic therapy. Lancet 266: 393-395.
26. Browne N, Heelan M, Kavanagh K. 2013. An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes. Virulence 4: 597-603.
27. Byrnes EJ III, Li W, Lewit Y, Ma H, Voelz K, Ren P, Carter DA, Chaturvedi V, Bildfell RJ, May RC, et al. 2010. Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States. PLoS Pathog 6: e1000850.
28. Cafarchia C, Iatta R, Latrofa MS, Graser Y, Otranto D. 2013. Molecular epidemiology, phylogeny and evolution of dermatophytes. Infect Genet Evol 20: 336-351.
29. Cain CW, Lohse MB, Homann OR, Sil A, Johnson AD. 2012. A conserved transcriptional regulator governs fungal morphology in widely diverged species. Genetics 190: 511-521.
30. Calderone RA, Fonzi WA. 2001. Virulence factors of Candida albicans. Trends Microbiol 9: 327-335.
31. Casadevall A. 2005. Fungal virulence, vertebrate endothermy, and dinosaur extinction: Is there a connection? Fungal Genet Biol 42: 98-106.
32. Casadevall A. 2010. Cryptococci at the brain gate: Break and enter or use a Trojan horse? J Clin Invest 120: 1389-1392.
33. Casadevall A. 2012. Fungi and the rise of mammals. PLoS Pathog 8: e1002808.
34. Casadevall A, Pirofski L. 2001. Host-pathogen interactions: The attributes of virulence. J Infect Dis 184: 337-344.
35. Casadevall A, Pirofski LA. 2007. Accidental virulence, cryptic pathogenesis, Martians, lost hosts, and the pathogenicity of environmental microbes. Eukaryot Cell 6: 2169-2174.
36. Casadevall A, Cleare W, Feldmesser M, Glatman-Freedman A, Goldman DL, Kozel TR, Lendvai N, Mukherjee J, Pirofski LA, Rivera J, et al. 1998. Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies. Antimicrob Agents Chemother 42: 1437-1446.
37. Chau TT, Mai NH, Phu NH, Nghia HD, Chuong LV, Sinh DX, Duong VA, Diep PT, Campbell JI, Baker S, et al. 2010. A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam-High prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease. BMC Infect Dis 10: 199.
38. Chen J, Varma A, Diaz MR, Litvintseva AP, Wollenberg KK, Kwon-Chung KJ. 2008. Cryptococcus neoformans strains and infection in apparently immunocompetent patients, China. Emerg Infect Dis 14: 755-762.
39. Chen YL, Lehman VN, Lewit Y, Averette AF, Heitman J. 2013. Calcineurin governs thermotolerance and virulence of Cryptococcus gattii. G3 (Bethesda) 3: 527-539.
40. Choi YH, Ngamskulrungroj P, Varma A, Sionov E, Hwang SM, Carriconde F, Meyer W, Litvintseva AP, Lee WG, Shin JH, et al. 2010. Prevalence of the VNIc genotype of Cryptococcus neoformans in non-HIV-associated cryptococcosis in the Republic of Korea. FEMS Yeast Res 10: 769-778.
41. Chun CD, Brown JC, Madhani HD. 2011. A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans. Cell Host Microbe 9: 243-251.
42. Citiulo F, Jacobsen ID, Miramon P, Schild L, Brunke S, Zipfel P, Brock M, Hube B, Wilson D. 2012. Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLoS Pathog 8: e1002777.
43. Cohen MS, Smith MK, Muessig KE, Hallett TB, Powers KA, Kashuba AD. 2013. Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: Where do we go from here? Lancet 382: 1515-1524.
44. Comerio RM, Andorno AV, Botto EN. 2008. Conidiobolus coronatus isolation from a pest aphids of chives (Allium schoenoprasum L.). Rev Iberoam Micol 25: 193-195.
45. Cramer RA Jr, Perfect BZ, Pinchai N, Park S, Perlin DS, Asfaw YG, Heitman J, Perfect JR, Steinbach WJ. 2008. Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus. Eukaryot Cell 7: 1085-1097.
46. Dahl MV. 1993. Suppression of immunity and inflammation by products produced by dermatophytes. J Am Acad Dermatol 28: S19-S23.
47. Dijksterhuis J, Samson RA. 2006. Zygomycetes. In Food spoilage microorganisms (ed. Blackburn CW), pp. 415-436. CRC, Boca Raton, FL.
48. Dizbay M, Adisen E, Kustimur S, Sari N, Cengiz B, Yalcin B, Kalkanci A, Gonul I I, Sugita T. 2009. Fungemia and cutaneous zygomycosis due to Mucor circinelloides in an intensive care unit patient: Case report and review of literature. Jpn J Infect Dis 62: 146-148.
49. Echetebu CO, Ononogbu IC. 1982. Extracellular lipase and proteinase of Basidiobolus haptosporus: Possible role in subcutaneous mycosis. Mycopathologia 80: 171-177.
50. Eckhart L, Valle LD, Jaeger K, Ballaun C, Szabo S, Nardi A, Buchberger M, Hermann M, Alibardi L, Tschachler E. 2008. Identification of reptilian genes encoding hair keratin-like proteins suggests a new scenario for the evolutionary origin of hair. Proc Natl Acad Sci 105: 18419-18423.
51. Edwards JA, Alore EA, Rappleye CA. 2011. The yeast-phase virulence requirement for a-glucan synthase differs among Histoplasma capsulatum chemotypes. Eukaryot Cell 10: 87-97.
52. Edwards JA, Chen C, Kemski MM, Hu J, Mitchell TK, Rappleye CA. 2013. Histoplasma yeast and mycelial transcriptomes reveal pathogenic-phase and lineage-specific gene expression profiles. BMC Genomics 14: 695.
53. Ellis DH, Pfeiffer TJ. 1990. Natural habitat of Cryptococcus neoformans var. gattii. J Clin Microbiol 28: 1642-1644.
54. Ernst JF, Pla J. 2011. Signaling the glycoshield: Maintenance of the Candida albicans cell wall. Int J Med Microbiol 301: 378-383.
55. Findley K, Rodriguez-Carres M, Metin B, Kroiss J, Fonseca A, Vilgalys R, Heitman J. 2009. Phylogeny and phenotypic characterization of pathogenic Cryptococcus species and closely related saprobic taxa in the Tremellales. Eukaryot Cell 8: 353-361.
56. Fisher MC, Koenig GL, White TJ, San-Blas G, Negroni R, Alvarez IG, Wanke B, Taylor JW. 2001. Biogeographic range expansion into South America by Coccidioides immitis mirrors New World patterns of human migration. Proc Natl Acad Sci 98: 4558-4562.
57. Forche A, Alby K, Schaefer D, Johnson AD, Berman J, Bennett RJ. 2008. The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains. PLoS Biol 6: e110.
58. Fortes ST, Lazera MS, Nishikawa MM, Macedo RC, Wanke B. 2001. First isolation of Crypstococcus neoformans var. gattii from a native jungle tree in the Brazilian Amazon rainforest. Mycoses 44: 137-140.
59. Fortes MR, Miot HA, Kurokawa CS, Marques ME, Marques SA. 2011. Immunology of paracoccidioidomycosis. An Bras Dermatol 86: 516-524.
60. Fraser JA, Giles SS, Wenink EC, Geunes-Boyer SG, Wright JR, Diezmann S, Allen A, Stajich JE, Dietrich FS, Perfect JR, et al. 2005. Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak. Nature 437: 1360-1364.
61. Fu Y, Lee H, Collins M, Tsai HF, Spellberg B, Edwards JE Jr, Kwon-Chung KJ, Ibrahim AS. 2004. Cloning and functional characterization of the Rhizopus oryzae high affinity iron permease (rFTR1) gene. FEMS Microbiol Lett 235: 169-176.
62. Garcia-Solache MA, Casadevall A. 2010. Global warming will bring new fungal diseases for mammals. MBio 1: e00061-10.
63. Gebremariam T, Liu M, Luo G, Bruno V, Phan QT, Waring AJ, Edwards JE Jr, Filler SG, Yeaman MR, Ibrahim AS. 2014. CotH3 mediates fungal invasion of host cells during mucormycosis. J Clin Invest 124: 237-250.
64. Ghannoum MA. 2000. Potential role of phospholipases in virulence and fungal pathogenesis. Clin Microbiol Rev 13: 122-143.
65. Gigliotti F, Limper AH, Wright T. 2014. Pneumocystis. Cold Spring Harb Perspect Med. doi: 10.1101/cshperspect.a019828.
66. Goddard MR, Godfray HC, Burt A. 2005. Sex increases the efficacy of natural selection in experimental yeast populations. Nature 434: 636-640.
67. Gradisar H, Friedrich J, Krizaj I, Jerala R. 2005. Similarities and specificities of fungal keratinolytic proteases: Comparison of keratinases of Paecilomyces marquandii and Doratomyces microsporus to some known proteases. Appl Environ Microbiol 71: 3420-3426.
68. Gugnani HC. 1992. Entomophthoromycosis due to Conidiobolus. Eur J Epidemiol 8: 391-396.
69. Hagen F, Ceresini PC, Polacheck I, Ma H, van Nieuwerburgh F, Gabaldon T, Kagan S, Pursall ER, Hoogveld HL, van Iersel LJ, et al. 2013. Ancient dispersal of the human fungal pathogen Cryptococcus gattii from the Amazon rainforest. PLoS ONE 8: e71148.
70. Heckman DS, Geiser DM, Eidell BR, Stauffer RL, Kardos NL, Hedges SB. 2001. Molecular evidence for the early colonization of land by fungi and plants. Science 293: 1129-1133.
71. Hickman MA, Zeng G, Forche A, Hirakawa MP, Abbey D, Harrison BD, Wang YM, Su CH, Bennett RJ, Wang Y, et al. 2013. The “obligate diploid” Candida albicans forms mating-competent haploids. Nature 494: 55-59.
72. Hoff GL, Bigler WJ. 1981. The role of bats in the propagation and spread of histoplasmosis: A review. J Wildl Dis 17: 191-196.
73. Hoffmann K, Pawlowska J, Walther G, Wrzosek M, de Hoog GS, Benny GL, Kirk PM, Voigt K. 2013. The family structure of the Mucorales: A synoptic revision based on comprehensive multigene-genealogies. Persoonia 30: 57-76.
74. Hogan DA, Muhlschlegel FA. 2011. Candida albicans developmental regulation: Adenylyl cyclase as a coincidence detector of parallel signals. Curr Opin Microbiol 14: 682-686.
75. Holbrook ED, Rappleye CA. 2008. Histoplasma capsulatum pathogenesis: Making a lifestyle switch. Curr Opin Microbiol 11: 318-324.
76. Holland WL, Summers SA. 2008. Sphingolipids, insulin resistance, and metabolic disease: New insights from in vivo manipulation of sphingolipid metabolism. Endocr Rev 29: 381-402.
77. Hospenthal DR, Kwon-Chung KJ, Bennett JE. 1998. Concentrations of airborne Aspergillus compared to the incidence of invasive aspergillosis: Lack of correlation. Med Mycol 36: 165-168.
78. Hoyer LL, Green CB, Oh SH, Zhao X. 2008. Discovering the secrets of the Candida albicans agglutinin-like sequence (ALS) gene family-A sticky pursuit. Med Mycol 46: 1-15.
79. Hull CM, Johnson AD. 1999. Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans. Science 285: 1271-1275.
80. Humphreys CP, Franks PJ, Rees M, Bidartondo MI, Leake JR, Beerling DJ. 2010. Mutualistic mycorrhiza-like symbiosis in the most ancient group of land plants. Nat Commun 1: 103.
81. Ibrahim AS. 2011. Host cell invasion in mucormycosis: Role of iron. Curr Opin Microbiol 14: 406-411.
82. Ibrahim AS, Edwards JE Jr, Fu Y, Spellberg B. 2006. Deferiprone iron chelation as a novel therapy for experimental mucormycosis. J Antimicrob Chemother 58: 1070-1073.
83. Ibrahim AS, Spellberg B, Edwards J Jr. 2008. Iron acquisition: A novel perspective on mucormycosis pathogenesis and treatment. Curr Opin Infect Dis 21: 620-625.
84. Ibrahim AS, Gebremariam T, Lin L, Luo G, Husseiny MI, Skory CD, Fu Y, French SW, Edwards JE Jr, Spellberg B. 2010. The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis. Mol Microbiol 77: 587-604.
85. Isa-Isa R, Arenas R, Fernandez RF, Isa M. 2012. Rhinofacial conidiobolomycosis (entomophthoramycosis). Clin Dermatol 30: 409-412.
86. Kam AP, Xu J. 2002. Diversity of commensal yeasts within and among healthy hosts. Diagn Microbiol Infect Dis 43: 19-28.
87. Kasuga T, Taylor JW, White TJ. 1999. Phylogenetic relationships of varieties and geographical groups of the human pathogenic fungus Histoplasma capsulatum Darling. J Clin Microbiol 37: 653-663.
88. Kasuga T, White TJ, Koenig G, McEwen J, Restrepo A, Castaneda E, Da Silva Lacaz C, Heins-Vaccari EM, De Freitas RS, Zancope-Oliveira RM, et al. 2003. Phylogeography of the fungal pathogen Histoplasma capsulatum. Mol Ecol 12: 3383-3401.
89. Kauffman CA. 2007. Histoplasmosis: A clinical and laboratory update. Clin Microbiol Rev 20: 115-132.
90. Kennedy AD, Willment JA, Dorward DW, Williams DL, Brown GD, DeLeo FR. 2007. Dectin-1 promotes fungicidal activity of human neutrophils. Eur J Immunol 37: 467-478.
91. Khan ZU, Ahmad S, Brazda A, Chandy R. 2009. Mucor circinelloides as a cause of invasive maxillofacial zygomycosis: An emerging dimorphic pathogen with reduced susceptibility to posaconazole. J Clin Microbiol 47: 1244-1248.
92. Kidd SE, Sorrell TC, Meyer W. 2003. Isolation of two molecular types of Cryptococcus neoformans var. gattii from insect frass. Med Mycol 41: 171-176.
93. Kidd SE, Hagen F, Tscharke RL, Huynh M, Bartlett KH, Fyfe M, Macdougall L, Boekhout T, Kwon-Chung KJ, Meyer W. 2004. A rare genotype of Cryptococcus gattii caused the cryptococcosis outbreak on Vancouver Island (British Columbia, Canada). Proc Natl Acad Sci 101: 17258-17263.
94. Kidd SE, Bach PJ, Hingston AO, Mak S, Chow Y, MacDougall L, Kronstad JW, Bartlett KH. 2007. Cryptococcus gattii dispersal mechanisms, British Columbia, Canada. Emerg Infect Dis 13: 51-57.
95. Kothary MH, Chase T Jr, Macmillan JD. 1984. Correlation of elastase production by some strains of Aspergillus fumigatus with ability to cause pulmonary invasive aspergillosis in mice. Infect Immun 43: 320-325.
96. Krcmery V, Barnes AJ. 2002. Non-albicans Candidaspp. causing fungaemia: Pathogenicity and antifungal resistance. J Hosp Infect 50: 243-260.
97. Krockenberger MB, Canfield PJ, Malik R. 2002. Cryptococcus neoformans in the koala (Phascolarctos cinereus): Colonization by C. n. var. gattii and investigation of environmental sources. Med Mycol 40: 263-272.
98. Kronstad JW, Attarian R, Cadieux B, Choi J, D’Souza CA, Griffiths EJ, Geddes JM, Hu G, Jung WH, Kretschmer M, et al. 2011. Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box. Nat Rev Microbiol 9: 193-203.
99. Kronstad JW, Hu G, Jung WH. 2013. An encapsulation of iron homeostasis and virulence in Cryptococcus neoformans. Trends Microbiol 21: 457-465.
100. Kumamoto CA. 2008. Molecular mechanisms of mechano- sensing and their roles in fungal contact sensing. Nat Rev Microbiol 6: 667-673.
101. Kwon-Chung KJ. 2012. Taxonomy of fungi causing mucormycosis and entomophthoramycosis (Zygomycosis) and nomenclature of the disease: Molecular mycologic perspectives. Clin Infect Dis 54: S8-S15.
102. Kwon-Chung KJ, Sugui JA. 2013. Aspergillus fumigates- What makes the species a ubiquitous human fungal pathogen? PLoS Pathog 9: e1003743.
103. Latgé JP. 1999. Aspergillus fumigatus and aspergillosis. Clin Microbiol Rev 12: 310-350.
104. Lee SC, Li A, Calo S, Heitman J. 2013. Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides. PLoS Pathog 9: e1003625.
105. Levitz SM, Diamond RD. 1985. Mechanisms of resistance of Aspergillus fumigatus Conidia to killing by neutrophils in vitro. J Infect Dis 152: 33-42.
106. Lin JS, Huang JH, Hung LY, Wu SY, Wu-Hsieh BA. 2010. Distinct roles of complement receptor 3, Dectin-1, and sialic acids in murine macrophage interaction with Histoplasma yeast. J Leukoc Biol 88: 95-106.
107. Litvintseva AP, Mitchell TG. 2012. Population genetic analyses reveal the African origin and strain variation of Cryptococcus neoformans var. grubii. PLoS Pathog 8: e1002495.
108. Liu Y, Filler SG. 2011. Candida albicans Als3, a multifunctional adhesin and invasin. Eukaryot Cell 10: 168-173.
109. Liu OW, Chun CD, Chow ED, Chen C, Madhani HD, Noble SM. 2008. Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans. Cell 135: 174-188.
110. Liu M, Spellberg B, Phan QT, Fu Y, Lee AS, Edwards JE Jr, Filler SG, Ibrahim AS. 2010. The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice. J Clin Invest 120: 1914-1924.
111. Lockhart SR, Wu W, Radke JB, Zhao R, Soll DR. 2005. Increased virulence and competitive advantage of a/a over a/a or a/a offspring conserves the mating system of Candida albicans. Genetics 169: 1883-1890.
112. Lott TJ, Fundyga RE, Kuykendall RJ, Arnold J. 2005. The human commensal yeast, Candida albicans, has an ancient origin. Fungal Genet Biol 42: 444-451.
113. Lucking R, Huhndorf S, Pfister DH, Plata ER, Lumbsch HT. 2009. Fungi evolved right on track. Mycologia 101: 810-822.
114. Ma LJ, van der Does HC, Borkovich KA, Coleman JJ, Daboussi MJ, Di Pietro A, Dufresne M, Freitag M, Grabherr M, Henrissat B, et al. 2010. Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium. Nature 464: 367-373.
115. Magee BB, Magee PT. 2000. Induction of mating in Candida albicans by construction of MTLa and MTLa strains. Science 289: 310-313.
116. Marples MJ, Di Menna ME. 1952. The incidence of Candida albicans in Dunedin, New Zealand. J Pathol Bacteriol 64: 497-502.
117. Marques SA. 2012. Paracoccidioidomycosis. Clin Dermatol 30: 610-615.
118. Marques SA. 2013. Paracoccidioidomycosis: Epidemiological, clinical, diagnostic and treatment up-dating. An Bras Dermatol 88: 700-711.
119. McCormick A, Heesemann L, Wagener J, Marcos V, Hartl D, Loeffler J, Heesemann J, Ebel F. 2010. NETs formed by human neutrophils inhibit growth of the pathogenic mold Aspergillus fumigatus. Microbes Infect 12: 928-936.
120. McGill S, Malik R, Saul N, Beetson S, Secombe C, Robertson I, Irwin P. 2009. Cryptococcosis in domestic animals in Western Australia: A retrospective study from 1995-2006. Med Mycol 47: 625-639.
121. McMurray DN, Greer DL. 1979. Immune responses in bats following intranasal infection with Histoplasma capsulatum. Am J Trop Med Hyg 28: 1036-1039.
122. Meyer W, Castaneda A, Jackson S, Huynh M, Castaneda E. 2003. Molecular typing of IberoAmerican Cryptococcus neoformans isolates. Emerg Infect Dis 9: 189-195.
123. Millanes AM, Truong C, Westberg M, Diederich P, Wedin M. 2014. Host switching promotes diversity in host-specialized mycoparasitic fungi: Uncoupled evolution in the Biatoropsis-Usnea system. Evolution doi:10.1111/evo.12374.
124. Miller MG, Johnson AD. 2002. White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating. Cell 110: 293-302.
125. Miller WG, Padhye AA, van Bonn W, Jensen E, Brandt ME, Ridgway SH. 2002. Cryptococcosis in a bottlenose dolphin (Tursiops truncatus) caused by Cryptococcus neoformans var. gattii. J Clin Microbiol 40: 721-724.
126. Mitchell TG, Perfect JR. 1995. Cryptococcosis in the era of AIDS-100 years after the discovery of Cryptococcus neoformans. Clin Microbiol Rev 8: 515-548.
127. Molez JF. 1998. The historical question of acquired immunodeficiency syndrome in the 1960s in the Congo River basin area in relation to cryptococcal meningitis. Am J Trop Med Hyg 58: 273-276.
128. Money NP, Davis CM, Ravishankar JP. 2004. Biomechanical evidence for convergent evolution of the invasive growth process among fungi and oomycete water molds. Fungal Genet Biol 41: 872-876.
129. Morita T, Kishimoto M, Shimada A, Matsumoto Y, Shindo J. 2001. Disseminated histoplasmosis in a sea otter (Enhydra lutris). J Comp Pathol 125: 219-223.
130. Morschhäuser J. 2011. Nitrogen regulation of morphogenesis and protease secretion in Candida albicans. Int J Med Microbiol 301: 390-394.
131. Morton CO, Bouzani M, Loeffler J, Rogers TR. 2012. Direct interaction studies between Aspergillus fumigatus and human immune cells: What have we learned about pathogenicity and host immunity? Front Microbiol 3: 413.
132. Mullins J, Harvey R, Seaton A. 1976. Sources and incidence of airborne Aspergillus fumigatus (Fres). Clin Allergy 6: 209-217.
133. Neilson JB, Ivey MH, Bulmer GS. 1978. Cryptococcus neoformans: Pseudohyphal forms surviving culture with Acanthamoeba polyphaga. Infect Immun 20: 262-266.
134. Nemecek JC, Wuthrich M, Klein BS. 2006. Global control of dimorphism and virulence in fungi. Science 312: 583-588.
135. Netea MG, Warris A, Van der Meer JW, Fenton MJ, Verver-Janssen TJ, Jacobs LE, Andresen T, Verweij PE, Kullberg BJ. 2003. Aspergillus fumigatus evades immune recognition during germination through loss of toll-like receptor-4-mediated signal transduction. J Infect Dis 188: 320-326.
136. Nguyen VQ, Sil A. 2008. Temperature-induced switch to the pathogenic yeast form of Histoplasma capsulatum requires Ryp1, a conserved transcriptional regulator. Proc Natl Acad Sci 105: 4880-4885.
137. Nguyen C, Barker BM, Hoover S, Nix DE, Ampel NM, Frelinger JA, Orbach MJ, Galgiani JN. 2013. Recent advances in our understanding of the environmental, epidemiological, immunological, and clinical dimensions of coccidioidomycosis. Clin Microbiol Rev 26: 505-525.
138. Nicol MR, Adams JL, Kashuba AD. 2013. HIV PrEP trials: The road to success. Clin Investig (Lond) 3: 295-308.
139. Nielsen K, De Obaldia AL, Heitman J. 2007. Cryptococcus neoformans mates on pigeon guano: Implications for the realized ecological niche and globalization. Eukaryot Cell 6: 949-959.
140. Noble SM. 2013. Candida albicans specializations for iron homeostasis: From commensalism to virulence. Curr Opin Microbiol 16: 708-715.
141. Noble SM, French S, Kohn LA, Chen V, Johnson AD. 2010. Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity. Nat Genet 42: 590-598.
142. Nucci M, Anaissie E. 2007. Fusarium infections in immunocompromised patients. Clin Microbiol Rev 20: 695-704.
143. O’Brien HE, Parrent JL, Jackson JA, Moncalvo JM, Vilgalys R. 2005. Fungal community analysis by large-scale sequencing of environmental samples. Appl Environ Microbiol 71: 5544-5550.
144. Odds FC. 1984. Ecology and epidemiology of Candida species. Zentralbl Bakteriol Mikrobiol Hyg A 257: 207-212.
145. Odds F. 1988. Candida and candidosis: A review and bibliography. Bailliere and Tindall, London.
146. O’Donnell K, Sutton DA, Rinaldi MG, Magnon KC, Cox PA, Revankar SG, Sanche S, Geiser DM, Juba JH, van Burik JA, et al. 2004. Genetic diversity of human pathogenic members of the Fusarium oxysporum complex inferred from multilocus DNA sequence data and amplified fragment length polymorphism analyses: Evidence for the recent dispersion of a geographically widespread clonal lineage and nosocomial origin. J Clin Microbiol 42: 5109-5120.
147. Okafor JI. 1994. Purification and characterization of protease enzymes of Basidiobolus and Conidiobolus species. Mycoses 37: 265-269.
148. Okafor JI, Gugnani HC. 1990. Lipase activity of Basidiobolus and Conidiobolus species. Mycoses 33: 81-85.
149. Okafor JI, Gugnani HC, Testratke D, Yangoo BG. 1987. Extracellular enzyme activities by Basidiobolus and Conidiobolus isolates on solid media. Mykosen 30: 404-407.
150. Okagaki LH, Strain AK, Nielsen JN, Charlier C, Baltes NJ, Chretien F, Heitman J, Dromer F, Nielsen K. 2010. Cryptococcal cell morphology affects host cell interactions and pathogenicity. PLoS Pathog 6: e1000953.
151. Oliveira DL, Nakayasu ES, Joffe LS, Guimaraes AJ, Sobreira TJ, Nosanchuk JD, Cordero RJ, Frases S, Casadevall A, Almeida IC, et al. 2010. Characterization of yeast extracellular vesicles: Evidence for the participation of different pathways of cellular traffic in vesicle biogenesis. PLoS ONE 5: e11113.
152. Paris S, Debeaupuis JP, Crameri R, Carey M, Charles F, Prevost MC, Schmitt C, Philippe B, Latgé JP. 2003. Conidial hydrophobins of Aspergillus fumigatus. Appl Environ Microbiol 69: 1581-1588.
153. Park BJ, Wannemuehler KA, Marston BJ, Govender N, Pappas PG, Chiller TM. 2009. Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS 23: 525-530.
154. Perera TH, Gregory DW, Marshall D, Gow NA. 1997. Contact-sensing by hyphae of dermatophytic and saprophytic fungi. J Med Vet Mycol 35: 289-293.
155. Pfaller MA, Diekema DJ. 2007. Epidemiology of invasive candidiasis: A persistent public health problem. Clin Microbiol Rev 20: 133-163.
156. Pihet M, Vandeputte P, Tronchin G, Renier G, Saulnier P, Georgeault S, Mallet R, Chabasse D, Symoens F, Bouchara JP. 2009. Melanin is an essential component for the integrity of the cell wall of Aspergillus fumigatus conidia. BMC Microbiol 9: 177.
157. Poole CJ, Wong M. 2013. Allergic bronchopulmonary aspergillosis in garden waste (compost) collectors-Occupational implications. Occup Med (Lond) 63: 517-519.
158. Prabhu RM, Patel R. 2004. Mucormycosis and entomophthoramycosis: A review of the clinical manifestations, diagnosis and treatment. Clin Microbiol Infect 10: 31-47.
159. Puccia R, Juliano MA, Juliano L, Travassos LR, Carmona AK. 1999. Detection of the basement membrane-degrading proteolytic activity of Paracoccidioides brasiliensis after SDS-PAGE using agarose overlays containing Abz-MKALTLQ-EDDnp. Braz J Med Biol Res 32: 645-649.
160. Puccia R, McEwen JG, Cisalpino PS. 2008. Diversity in Paracoccidioides brasiliensis. The PbGP43 gene as a genetic marker. Mycopathologia 165: 275-287.
161. Puccia R, Vallejo MC, Matsuo AL, Longo LV. 2011. The paracoccidioides cell wall: Past and present layers toward understanding interaction with the host. Front Microbiol 2: 257.
162. Pukkila-Worley R, Mylonakis E. 2008. Epidemiology and management of cryptococcal meningitis: Developments and challenges. Expert Opin Pharmacother 9: 551-560.
163. Quan C, Spellberg B. 2010. Mucormycosis, pseudallescheriasis, and other uncommon mold infections. Proc Am Thorac Soc 7: 210-215.
164. Queiroz-Telles F, Escuissato DL. 2011. Pulmonary paracoccidioidomycosis. Semin Respir Crit Care Med 32: 764-774.
165. Quist EM, Belcher C, Levine G, Johnson M, Heatley JJ, Kiupel M, Giri D. 2011. Disseminated histoplasmosis with concurrent oral candidiasis in an Eclectus parrot (Eclectus roratus). Avian Pathol 40: 207-211.
166. Rappleye CA, Engle JT, Goldman WE. 2004. RNA interference in Histoplasma capsulatum demonstrates a role for a(1,3)-glucan in virulence. Mol Microbiol 53: 153-165.
167. Rappleye CA, Eissenberg LG, Goldman WE. 2007. Histoplasma capsulatum a(1,3)-glucan blocks innate immune recognition by the b-glucan receptor. Proc Natl Acad Sci 104: 1366-1370.
168. Raso TF, Werther K, Miranda ET, Mendes-Giannini MJ. 2004. Cryptococcosis outbreak in psittacine birds in Brazil. Med Mycol 42: 355-362.
169. Redecker D, Kodner R, Graham LE. 2000. Glomalean fungi from the Ordovician. Science 289: 1920-1921.
170. Rep M, Kistler HC. 2010. The genomic organization of plant pathogenicity in Fusarium species. Curr Opin Plant Biol 13: 420-426.
171. Ribes JA, Vanover-Sams CL, Baker DJ. 2000. Zygomycetes in human disease. Clin Microbiol Rev 13: 236-301.
172. Richini-Pereira VB, Bosco Sde M, Theodoro RC, Macoris SA, Bagagli E. 2009. Molecular approaches for eco-epidemiological studies of Paracoccidioides brasiliensis. Mem Inst Oswaldo Cruz 104: 636-643.
173. Robert VA, Casadevall A. 2009. Vertebrate endothermy restricts most fungi as potential pathogens. J Infect Dis 200: 1623-1626.
174. Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, Sarkisova TA, Schaufele RL, Sein M, Sein T, Chiou CC, Chu JH, et al. 2005. Epidemiology and outcome of zygomycosis: A review of 929 reported cases. Clin Infect Dis 41: 634-653.
175. Rodrigues ML, Nimrichter L, Oliveira DL, Frases S, Miranda K, Zaragoza O, Alvarez M, Nakouzi A, Feldmesser M, Casadevall A. 2007. Vesicular polysaccharide export in Cryptococcus neoformans is a eukaryotic solution to the problem of fungal trans-cell wall transport. Eukaryot Cell 6: 48-59.
176. Rodrigues ML, Nakayasu ES, Oliveira DL, Nimrichter L, Nosanchuk JD, Almeida IC, Casadevall A. 2008. Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence. Eukaryot Cell 7: 58-67.
177. Rohde JR, Cardenas ME. 2004. Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi. Curr Top Microbiol Immunol 279: 53-72.
178. Rohm M, Grimm MJ, D’Auria AC, Almyroudis NG, Segal BH, Urban CF. 2014. NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis. Infect Immun 82: 1766-1777.
179. Saijo T, Chen J, Chen SC, Rosen LB, Yi J, Sorrell TC, Bennett JE, Holland SM, Browne SK, Kwon-Chung KJ. 2014. Anti-granulocyte-macrophage colony-stimulating factor autoantibodies are a risk factor for central nervous system infection by Cryptococcus gattii in otherwise immuno- competent patients. MBio 5: e00912-14.
180. Santos WR, Meyer W, Wanke B, Costa SP, Trilles L, Nascimento JL, Medeiros R, Morales BP, Bezerra Cde C, Macedo RC, et al. 2008. Primary endemic Cryptococcosis gattii by molecular type VGII in the state of Para, Brazil. Mem Inst Oswaldo Cruz 103: 813-818.
181. Schaller M, Borelli C, Korting HC, Hube B. 2005. Hydrolytic enzymes as virulence factors of Candida albicans. Mycoses 48: 365-377.
182. Schmitt HJ, Blevins A, Sobeck K, Armstrong D. 1990. Aspergillus species from hospital air and from patients. Mycoses 33: 539-541.
183. Sebghati TS, Engle JT, Goldman WE. 2000. Intracellular parasitism by Histoplasma capsulatum: Fungal virulence and calcium dependence. Science 290: 1368-1372.
184. Shankar J, Restrepo A, Clemons KV, Stevens DA. 2011. Hormones and the resistance of women to paracoccidioido- mycosis. Clin Microbiol Rev 24: 296-313.
185. Shapiro RS, Ryan O, Boone C, Cowen LE. 2012. Regulatory circuitry governing morphogenesis in Saccharomyces cerevisiae and Candida albicans. Cell Cycle 11: 4294-4295.
186. Shen J, Cowen LE, Griffin AM, Chan L, Köhler JR. 2008. The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation. Proc Natl Acad Sci 105: 20918-20923.
187. Shi M, Li SS, Zheng C, Jones GJ, Kim KS, Zhou H, Kubes P, Mody CH. 2010. Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain. J Clin Invest 120: 1683-1693.
188. Shiraki Y, Ishibashi Y, Hiruma M, Nishikawa A, Ikeda S. 2006. Cytokine secretion profiles of human keratinocytes during Trichophyton tonsurans and Arthroderma benhamiae infections. J Med Microbiol 55: 1175-1185.
189. Siegfried N, van der Merwe L, Brocklehurst P, Sint TT. 2011. Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection. Cochrane Database Syst Rev CD003510.
190. Simwami SP, Khayhan K, Henk DA, Aanensen DM, Boekhout T, Hagen F, Brouwer AE, Harrison TS, Donnelly CA, Fisher MC. 2011. Low diversity Cryptococcus neoformans variety grubii multilocus sequence types from Thailand are consistent with an ancestral African origin. PLoS Pathog 7: e1001343.
191. Skinner CE, Fletcher DW. 1960. A review of the genus Candida. Bacteriol Rev 24: 397-416.
192. Smith RM, Schaefer MK, Kainer MA, Wise M, Finks J, Duwve J, Fontaine E, Chu A, Carothers B, Reilly A, et al. 2013. Fungal infections associated with contaminated methylprednisolone injections. N Engl J Med 369: 1598-1609.
193. Soll DR. 2002. Candida commensalism and virulence: The evolution of phenotypic plasticity. Acta Trop 81: 101-110.
194. Soll DR, Galask R, Schmid J, Hanna C, Mac K, Morrow B. 1991. Genetic dissimilarity of commensal strains of Candida spp. carried in different anatomical locations of the same healthy women. J Clin Microbiol 29: 1702-1710.
195. Speed B, Dunt D. 1995. Clinical and host differences between infections with the two varieties of Cryptococcus neoformans. Clin Infect Dis 21: 28-34; discussion 35-36.
196. Spellberg B, Edwards J Jr, Ibrahim A. 2005. Novel perspectives on mucormycosis: Pathophysiology, presentation, and management. Clin Microbiol Rev 18: 556-569.
197. Spellberg B, Andes D, Perez M, Anglim A, Bonilla H, Mathisen GE, Walsh TJ, Ibrahim AS. 2009. Safety and outcomes of open-label deferasirox iron chelation therapy for mucormycosis. Antimicrob Agents Chemother 53: 3122-3125.
198. Springer DJ, Phadke S, Billmyre B, Heitman J. 2012. Cryptococcus gattii, no longer an accidental pathogen? Curr Fungal Infect Rep 6: 245-256.
199. Staab JF, Bradway SD, Fidel PL, Sundstrom P. 1999. Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1. Science 283: 1535-1538.
200. Staib P, Kretschmar M, Nichterlein T, Hof H, Morschhäuser J. 2000. Differential activation of a Candida albicans virulence gene family during infection. Proc Natl Acad Sci 97: 6102-6107.
201. Steenbergen JN, Shuman HA, Casadevall A. 2001. Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages. Proc Natl Acad Sci 98: 15245-15250.
202. Steenbergen JN, Nosanchuk JD, Malliaris SD, Casadevall A. 2003. Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoideum. Infect Immun 71: 4862-4872.
203. Steenbergen JN, Nosanchuk JD, Malliaris SD, Casadevall A. 2004. Interaction of Blastomyces dermatitidis, Sporothrix schenckii, and Histoplasma capsulatum with Acanthamoeba castellanii. Infect Immun 72: 3478-3488.
204. Sudbery P, Gow N, Berman J. 2004. The distinct morphogenic states of Candida albicans. Trends Microbiol 12: 317-324.
205. Sundstrom P. 2002. Adhesion in Candida spp. Cell Microbiol 4: 461-469.
206. Taylor ML, Chavez-Tapia CB, Vargas-Yanez R, Rodriguez-Arellanes G, Pena-Sandoval GR, Toriello C, Perez A, Reyes-Montes MR. 1999. Environmental conditions favoring bat infection with Histoplasma capsulatum in Mexican shelters. Am J Trop Med Hyg 61: 914-919.
207. Thau N, Monod M, Crestani B, Rolland C, Tronchin G, Latgé JP, Paris S. 1994. rodletless mutants of Aspergillus fumigatus. Infect Immun 62: 4380-4388.
208. Theodoro RC, Teixeira Mde M, Felipe MS, Paduan Kdos S, Ribolla PM, San-Blas G, Bagagli E. 2012. Genus paracoccidioides: Species recognition and biogeographic aspects. PLoS ONE 7: e37694.
209. Torres HA, Rivero GA, Lewis RE, Hachem R, Raad I I, Kontoyiannis DP. 2003. Aspergillosis caused by non-fumigatus Aspergillus species: Risk factors and in vitro susceptibility compared with Aspergillus fumigatus. Diagn Microbiol Infect Dis 46: 25-28.
210. Trofa D, Soghier L, Long C, Nosanchuk JD, Gacser A, Goldman DL. 2011. A rat model of neonatal candidiasis demonstrates the importance of lipases as virulence factors for Candida albicans and Candida parapsilosis. Mycopathologia 172: 169-178.
211. Tucker SC, Casadevall A. 2002. Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm. Proc Natl Acad Sci 99: 3165-3170.
212. Underhill DM, Rossnagle E, Lowell CA, Simmons RM. 2005. Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. Blood 106: 2543-2550.
213. Untereiner WA, Scott JA, Naveau FA, Sigler L, Bachewich J, Angus A. 2004. The Ajellomycetaceae, a new family of vertebrate-associated Onygenales. Mycologia 96: 812-821.
214. Vallejo MC, Matsuo AL, Ganiko L, Medeiros LC, Miranda K, Silva LS, Freymuller-Haapalainen E, Sinigaglia-Coimbra R, Almeida IC, Puccia R. 2011. The pathogenic fungus Paracoccidioides brasiliensis exports extracellular vesicles containing highly immunogenic a-galactosyl epitopes. Eukaryot Cell 10: 343-351.
215. Vallejo MC, Nakayasu ES, Matsuo AL, Sobreira TJ, Longo LV, Ganiko L, Almeida IC, Puccia R. 2012. Vesicle and vesicle-free extracellular proteome of Paracoccidioides brasiliensis: Comparative analysis with other pathogenic fungi. J Proteome Res 11: 1676-1685.
216. Vikram HR, Smilack JD, Leighton JA, Crowell MD, De Petris G. 2012. Emergence of gastrointestinal basidiobolomycosis in the United States, with a review of worldwide cases. Clin Infect Dis 54: 1685-1691.
217. Vilela R, Rosa PS, Belone AF, Taylor JW, Diorio SM, Mendoza L. 2009. Molecular phylogeny of animal pathogen Lacazia loboi inferred from rDNA and DNA coding sequences. Mycol Res 113: 851-857.
218. Wang Y, Aisen P, Casadevall A. 1995. Cryptococcus neoformans melanin and virulence: Mechanism of action. Infect Iimmun 63: 3131-3136.
219. Wasylnka JA, Moore MM. 2003. Aspergillus fumigatus conidia survive and germinate in acidic organelles of A549 epithelial cells. J Cell Sci 116: 1579-1587.
220. Webster RH, Sil A. 2008. Conserved factors Ryp2 and Ryp3 control cell morphology and infectious spore formation in the fungal pathogen Histoplasma capsulatum. Proc Natl Acad Sci 105: 14573-14578.
221. Weissman Z, Shemer R, Conibear E, Kornitzer D. 2008. An endocytic mechanism for haemoglobin-iron acquisition in Candida albicans. Mol Microbiol 69: 201-217.
222. Weitzman I, Summerbell RC. 1995. The dermatophytes. Clin Microbiol Rev 8: 240-259.
223. Werner JL, Metz AE, Horn D, Schoeb TR, Hewitt MM, Schwiebert LM, Faro-Trindade I, Brown GD, Steele C. 2009. Requisite role for the dectin-1 b-glucan receptor in pulmonary defense against Aspergillus fumigatus. J Immunol 182: 4938-4946.
224. Wheeler RT, Fink GR. 2006. A drug-sensitive genetic network masks fungi from the immune system. PLoS Pathog 2: e35.
225. Wieloch W, Bogus MI, Ligeza M, Koszela-Piotrowska I, Szewczyk A. 2011. Coronatin-1 isolated from entomopathogenic fungus Conidiobolus coronatus kills Galleria mellonella hemocytes in vitro and forms potassium channels in planar lipid membrane. Toxicon 58: 369-379.
226. Williams MJ. 2007. Drosophila hemopoiesis and cellular immunity. J Immunol 178: 4711-4716.
227. Windus DW, Stokes TJ, Julian BA, Fenves AZ. 1987. Fatal Rhizopus infections in hemodialysis patients receiving deferoxamine. Ann Intern Med 107: 678-680.
228. Wrobel L, Whittington JK, Pujol C, Oh SH, Ruiz MO, Pfaller MA, Diekema DJ, Soll DR, Hoyer LL. 2008. Molecular phylogenetic analysis of a geographically and temporally matched set of Candida albicans isolates from humans and nonmigratory wildlife in central Illinois. Eukaryot Cell 7: 1475-1486.
229. Wu W, Lockhart SR, Pujol C, Srikantha T, Soll DR. 2007. Heterozygosity of genes on the sex chromosome regulates Candida albicans virulence. Mol Microbiol 64: 1587-1604.
230. Wu Y, Yang J, Yang F, Liu T, Leng W, Chu Y, Jin Q. 2009. Recent dermatophyte divergence revealed by comparative and phylogenetic analysis of mitochondrial genomes. BMC Genomics 10: 238.
231. Youseff BH, Dougherty JA, Rappleye CA. 2009. Reverse genetics through random mutagenesis in Histoplasma capsulatum. BMC Microbiol 9: 236.
232. Zaragoza O, Garcia-Rodas R, Nosanchuk JD, Cuenca-Estrella M, Rodriguez-Tudela JL, Casadevall A. 2010. Fungal cell gigantism during mammalian infection. PLoS Pathog 6: e1000945.
233. Zavasky DM, Samowitz W, Loftus T, Segal H, Carroll K. 1999. Gastrointestinal zygomycotic infection caused by Basidiobolus ranarum: Case report and review. Clin Infect Dis 28: 1244-1248.
234. Zimmerman LE. 1955. Fatal fungus infections complicating other diseases. Am J Clin Pathol 25: 46-65.
235. Zugmaier W, Bauer R, Oberwinkler F. 1994. Mycoparasitism of some Tremella species. Mycologia 86: 49-56.